TTC33 (tetratricopeptide repeat domain 33) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: TTC33 (tetratricopeptide repeat domain 33) Homo sapiens
Analyze
Symbol: TTC33
Name: tetratricopeptide repeat domain 33
RGD ID: 1606815
HGNC Page HGNC:29959
Description: ASSOCIATED WITH Neurodevelopmental Disorders; INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; arsenite(3-)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: osmosis responsive factor; osmosis-responsive factor; OSRF; tetratricopeptide repeat protein 33; TPR repeat protein 33
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38540,711,576 - 40,755,961 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl540,512,333 - 40,755,963 (-)EnsemblGRCh38hg38GRCh38
GRCh37540,711,678 - 40,756,063 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36540,747,435 - 40,791,829 (-)NCBINCBI36Build 36hg18NCBI36
Celera540,600,249 - 40,644,657 (-)NCBICelera
Cytogenetic Map5p13.1NCBI
HuRef540,663,704 - 40,707,894 (-)NCBIHuRef
CHM1_1540,713,552 - 40,757,967 (-)NCBICHM1_1
T2T-CHM13v2.0540,967,941 - 41,012,360 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:16344560   PMID:19322201   PMID:20360068   PMID:23455924   PMID:24981860   PMID:25416956   PMID:25798074   PMID:26186194   PMID:27880917   PMID:28330616  
PMID:28514442   PMID:30021884   PMID:31515488   PMID:32296183   PMID:32814053   PMID:33961781   PMID:34189442   PMID:35271311  


Genomics

Comparative Map Data
TTC33
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38540,711,576 - 40,755,961 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl540,512,333 - 40,755,963 (-)EnsemblGRCh38hg38GRCh38
GRCh37540,711,678 - 40,756,063 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36540,747,435 - 40,791,829 (-)NCBINCBI36Build 36hg18NCBI36
Celera540,600,249 - 40,644,657 (-)NCBICelera
Cytogenetic Map5p13.1NCBI
HuRef540,663,704 - 40,707,894 (-)NCBIHuRef
CHM1_1540,713,552 - 40,757,967 (-)NCBICHM1_1
T2T-CHM13v2.0540,967,941 - 41,012,360 (-)NCBIT2T-CHM13v2.0
Ttc33
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39155,214,971 - 5,247,817 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl155,215,006 - 5,247,817 (+)EnsemblGRCm39 Ensembl
GRCm38155,185,490 - 5,218,336 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl155,185,525 - 5,218,336 (+)EnsemblGRCm38mm10GRCm38
MGSCv37155,135,560 - 5,168,336 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36155,132,775 - 5,165,551 (+)NCBIMGSCv36mm8
Celera155,035,095 - 5,067,874 (+)NCBICelera
Cytogenetic Map15A1NCBI
cM Map151.99NCBI
Ttc33
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8256,007,377 - 56,054,312 (+)NCBIGRCr8
mRatBN7.2254,279,906 - 54,326,851 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl254,279,997 - 54,323,871 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx261,386,644 - 61,428,964 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0259,445,324 - 59,487,639 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0254,455,950 - 54,498,071 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0254,897,320 - 54,944,241 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl254,897,424 - 54,939,514 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0273,921,771 - 73,967,083 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4254,367,846 - 54,409,972 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera249,927,867 - 49,969,974 (+)NCBICelera
Cytogenetic Map2q16NCBI
Ttc33
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542625,017,351 - 25,075,039 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542625,017,351 - 25,075,164 (-)NCBIChiLan1.0ChiLan1.0
TTC33
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2469,578,211 - 69,625,486 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1567,732,829 - 67,779,117 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0569,623,962 - 69,665,450 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1574,669,939 - 74,713,898 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl574,669,939 - 74,820,697 (+)Ensemblpanpan1.1panPan2
TTC33
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1468,617,895 - 68,653,104 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl468,617,594 - 68,648,929 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha468,294,841 - 68,329,833 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0469,124,959 - 69,159,953 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl469,125,220 - 69,159,910 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1468,884,203 - 68,919,180 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0468,997,291 - 69,032,287 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0469,536,372 - 69,571,370 (+)NCBIUU_Cfam_GSD_1.0
Ttc33
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213229,472,118 - 229,524,282 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365181,847,544 - 1,899,888 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365181,847,567 - 1,896,712 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTC33
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1625,674,665 - 25,741,919 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11625,695,932 - 25,741,962 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TTC33
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1439,469,874 - 39,509,570 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607129,891,667 - 29,935,967 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ttc33
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475914,178,411 - 14,236,007 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475914,178,314 - 14,241,933 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TTC33
16 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 5p14.1-q11.1(chr5:26593632-50288555)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051834]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051834]|See cases [RCV000051834] Chr5:26593632..50288555 [GRCh38]
Chr5:26593741..49584389 [GRCh37]
Chr5:26629498..49620146 [NCBI36]
Chr5:5p14.1-q11.1		 pathogenic
GRCh38/hg38 5p13.2-12(chr5:35700480-45260029)x3 copy number gain See cases [RCV000051835] Chr5:35700480..45260029 [GRCh38]
Chr5:35700582..45260131 [GRCh37]
Chr5:35736339..45295888 [NCBI36]
Chr5:5p13.2-12		 pathogenic
GRCh38/hg38 5p13.2-q11.1(chr5:36374107-51103841)x3 copy number gain See cases [RCV000051836] Chr5:36374107..51103841 [GRCh38]
Chr5:36374209..50399675 [GRCh37]
Chr5:36409966..50435432 [NCBI36]
Chr5:5p13.2-q11.1		 pathogenic
GRCh38/hg38 5p15.33-12(chr5:54839-45649861)x3 copy number gain See cases [RCV000051810] Chr5:54839..45649861 [GRCh38]
Chr5:54954..45649963 [GRCh37]
Chr5:107954..45685720 [NCBI36]
Chr5:5p15.33-12		 pathogenic
GRCh38/hg38 5p15.33-11(chr5:49978-46114984)x3 copy number gain See cases [RCV000135453] Chr5:49978..46114984 [GRCh38]
Chr5:50093..46115086 [GRCh37]
Chr5:103093..46150843 [NCBI36]
Chr5:5p15.33-11		 pathogenic
GRCh38/hg38 5p13.2-q12.1(chr5:35201559-61903141)x3 copy number gain See cases [RCV000137302] Chr5:35201559..61903141 [GRCh38]
Chr5:35201661..61198968 [GRCh37]
Chr5:35237418..61234725 [NCBI36]
Chr5:5p13.2-q12.1		 pathogenic
GRCh38/hg38 5p15.33-q13.3(chr5:22149-74412725)x3 copy number gain See cases [RCV000138780] Chr5:22149..74412725 [GRCh38]
Chr5:22149..73708550 [GRCh37]
Chr5:75149..73744306 [NCBI36]
Chr5:5p15.33-q13.3		 pathogenic
GRCh37/hg19 5p15.2-12(chr5:13461664-46098927)x3 copy number gain See cases [RCV000239779] Chr5:13461664..46098927 [GRCh37]
Chr5:5p15.2-12		 pathogenic
GRCh37/hg19 5p14.2-11(chr5:24281195-46389339)x3 copy number gain See cases [RCV000512120] Chr5:24281195..46389339 [GRCh37]
Chr5:5p14.2-11		 likely pathogenic
GRCh37/hg19 5p15.1-q35.2(chr5:17628741-176575720)x1 copy number loss See cases [RCV000511978] Chr5:17628741..176575720 [GRCh37]
Chr5:5p15.1-q35.2		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3 copy number gain See cases [RCV000512039] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789) copy number gain See cases [RCV000510723] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
Single allele deletion not provided [RCV000677930] Chr5:39250414..40714234 [GRCh38]
Chr5:39250513..40714333 [GRCh37]
Chr5:5p13.1		 uncertain significance
GRCh37/hg19 5p14.1-12(chr5:27227243-45685844)x3 copy number gain not provided [RCV000682542] Chr5:27227243..45685844 [GRCh37]
Chr5:5p14.1-12		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3 copy number gain not provided [RCV000744323] Chr5:25328..180693344 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
GRCh37/hg19 5p13.3-12(chr5:31351588-43480111)x3 copy number gain not provided [RCV000744593] Chr5:31351588..43480111 [GRCh37]
Chr5:5p13.3-12		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3 copy number gain not provided [RCV000744317] Chr5:13648..180905029 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
GRCh37/hg19 5p13.2-11(chr5:36053583-46389339)x3 copy number gain musculoskeletal system issues [RCV002284293] Chr5:36053583..46389339 [GRCh37]
Chr5:5p13.2-11		 pathogenic
Single allele deletion Neurodevelopmental disorder [RCV000787436] Chr5:14685137..149511942 [GRCh37]
Chr5:5p15.2-q32		 uncertain significance
GRCh37/hg19 5p13.2-11(chr5:34453883-46389339)x3 copy number gain not provided [RCV000848003] Chr5:34453883..46389339 [GRCh37]
Chr5:5p13.2-11		 pathogenic
GRCh37/hg19 5p13.1-q11.1(chr5:38432180-49441945)x3 copy number gain not provided [RCV001005674] Chr5:38432180..49441945 [GRCh37]
Chr5:5p13.1-q11.1		 pathogenic
NM_012382.3(TTC33):c.226C>T (p.Arg76Trp) single nucleotide variant not specified [RCV004296088] Chr5:40730339 [GRCh38]
Chr5:40730441 [GRCh37]
Chr5:5p13.1		 uncertain significance
GRCh37/hg19 5p13.3-12(chr5:29081195-45294031)x3 copy number gain See cases [RCV001310288] Chr5:29081195..45294031 [GRCh37]
Chr5:5p13.3-12		 pathogenic
GRCh37/hg19 5p13.2-11(chr5:34984696-46405042)x3 copy number gain not provided [RCV001537930] Chr5:34984696..46405042 [GRCh37]
Chr5:5p13.2-11		 pathogenic
GRCh37/hg19 5p14.1-11(chr5:26382110-46389339) copy number gain not specified [RCV002053485] Chr5:26382110..46389339 [GRCh37]
Chr5:5p14.1-11		 pathogenic
GRCh37/hg19 5p13.3-11(chr5:29348753-46389339)x3 copy number gain not provided [RCV002474514] Chr5:29348753..46389339 [GRCh37]
Chr5:5p13.3-11		 pathogenic
NM_012382.3(TTC33):c.130A>G (p.Ile44Val) single nucleotide variant not specified [RCV004141342] Chr5:40746889 [GRCh38]
Chr5:40746991 [GRCh37]
Chr5:5p13.1		 uncertain significance
NM_012382.3(TTC33):c.403C>T (p.Arg135Cys) single nucleotide variant not specified [RCV004084819] Chr5:40728377 [GRCh38]
Chr5:40728479 [GRCh37]
Chr5:5p13.1		 uncertain significance
NM_012382.3(TTC33):c.581C>T (p.Thr194Ile) single nucleotide variant not specified [RCV004231272] Chr5:40716353 [GRCh38]
Chr5:40716455 [GRCh37]
Chr5:5p13.1		 uncertain significance
NM_012382.3(TTC33):c.377C>T (p.Ser126Leu) single nucleotide variant not specified [RCV004216969] Chr5:40728403 [GRCh38]
Chr5:40728505 [GRCh37]
Chr5:5p13.1		 uncertain significance
NM_012382.3(TTC33):c.56C>G (p.Ser19Cys) single nucleotide variant not specified [RCV004123751] Chr5:40746963 [GRCh38]
Chr5:40747065 [GRCh37]
Chr5:5p13.1		 uncertain significance
NM_012382.3(TTC33):c.518C>T (p.Thr173Met) single nucleotide variant not specified [RCV004070940] Chr5:40716416 [GRCh38]
Chr5:40716518 [GRCh37]
Chr5:5p13.1		 uncertain significance
NM_012382.3(TTC33):c.743A>G (p.Asp248Gly) single nucleotide variant not specified [RCV004253501] Chr5:40716191 [GRCh38]
Chr5:40716293 [GRCh37]
Chr5:5p13.1		 uncertain significance
NM_012382.3(TTC33):c.13G>A (p.Gly5Arg) single nucleotide variant not specified [RCV004272561] Chr5:40747006 [GRCh38]
Chr5:40747108 [GRCh37]
Chr5:5p13.1		 uncertain significance
NM_012382.3(TTC33):c.428T>G (p.Ile143Arg) single nucleotide variant not specified [RCV004310116] Chr5:40728352 [GRCh38]
Chr5:40728454 [GRCh37]
Chr5:5p13.1		 uncertain significance
NM_012382.3(TTC33):c.227G>A (p.Arg76Gln) single nucleotide variant not specified [RCV004339583] Chr5:40730338 [GRCh38]
Chr5:40730440 [GRCh37]
Chr5:5p13.1		 uncertain significance
NM_012382.3(TTC33):c.557A>G (p.Lys186Arg) single nucleotide variant not specified [RCV004353920] Chr5:40716377 [GRCh38]
Chr5:40716479 [GRCh37]
Chr5:5p13.1		 uncertain significance
GRCh38/hg38 5p13.3-12(chr5:29299893-45899898)x3 copy number gain See cases [RCV003482191] Chr5:29299893..45899898 [GRCh38]
Chr5:5p13.3-12		 likely pathogenic
NM_012382.3(TTC33):c.136C>T (p.Arg46Cys) single nucleotide variant not specified [RCV004479190] Chr5:40746883 [GRCh38]
Chr5:40746985 [GRCh37]
Chr5:5p13.1		 uncertain significance
NM_012382.3(TTC33):c.505T>C (p.Ser169Pro) single nucleotide variant not specified [RCV004479191] Chr5:40716429 [GRCh38]
Chr5:40716531 [GRCh37]
Chr5:5p13.1		 uncertain significance
NM_012382.3(TTC33):c.611A>G (p.Tyr204Cys) single nucleotide variant not specified [RCV004479192] Chr5:40716323 [GRCh38]
Chr5:40716425 [GRCh37]
Chr5:5p13.1		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:729
Count of miRNA genes:442
Interacting mature miRNAs:491
Transcripts:ENST00000337702, ENST00000503936, ENST00000504251, ENST00000511730
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
STS-N63422  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37540,711,738 - 40,711,885UniSTSGRCh37
GRCh37540,711,860 - 40,712,014UniSTSGRCh37
Build 36540,747,617 - 40,747,771RGDNCBI36
Celera540,600,309 - 40,600,456UniSTS
Celera540,600,431 - 40,600,585RGD
Cytogenetic Map5p13.1UniSTS
HuRef540,663,764 - 40,663,911UniSTS
HuRef540,663,886 - 40,664,040UniSTS
GeneMap99-GB4 RH Map5147.62UniSTS
NCBI RH Map5145.8UniSTS
D5S1543  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37540,736,538 - 40,736,658UniSTSGRCh37
Build 36540,772,295 - 40,772,415RGDNCBI36
Celera540,625,121 - 40,625,241RGD
Cytogenetic Map5p13.1UniSTS
HuRef540,688,364 - 40,688,484UniSTS
Whitehead-YAC Contig Map5 UniSTS
TTC33  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37540,716,391 - 40,716,588UniSTSGRCh37
Celera540,604,962 - 40,605,159UniSTS
HuRef540,668,417 - 40,668,614UniSTS
STS-N63422  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5p13.1UniSTS
GeneMap99-GB4 RH Map5155.46UniSTS
NCBI RH Map5145.8UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 160 58 173 107 502 111 321 67 240 225 248 347 10 1 4 48 1
Low 2278 2612 1553 517 1170 354 4035 2089 3472 193 1212 1266 164 1199 2739 5 2
Below cutoff 1 321 279 1 41 22 1 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_012382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011514003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054352255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC008810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC093264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF023244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF130073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI174764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK307131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK312560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC015701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC036536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE869916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF509085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM543635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM689740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ922097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR738110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA518274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA652008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000337702   ⟹   ENSP00000338533
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl540,711,576 - 40,755,961 (-)Ensembl
RefSeq Acc Id: ENST00000503936
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl540,715,136 - 40,755,945 (-)Ensembl
RefSeq Acc Id: ENST00000504251
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl540,715,944 - 40,755,960 (-)Ensembl
RefSeq Acc Id: ENST00000511730
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl540,716,145 - 40,755,949 (-)Ensembl
RefSeq Acc Id: ENST00000636106   ⟹   ENSP00000490018
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl540,611,492 - 40,755,963 (-)Ensembl
RefSeq Acc Id: ENST00000636863   ⟹   ENSP00000490389
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl540,512,333 - 40,755,908 (-)Ensembl
RefSeq Acc Id: ENST00000637375   ⟹   ENSP00000490134
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl540,568,105 - 40,755,948 (-)Ensembl
RefSeq Acc Id: NM_012382   ⟹   NP_036514
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38540,711,576 - 40,755,961 (-)NCBI
GRCh37540,711,678 - 40,756,072 (-)RGD
GRCh37540,711,678 - 40,756,072 (-)NCBI
Build 36540,747,435 - 40,791,829 (-)NCBI Archive
Celera540,600,249 - 40,644,657 (-)RGD
HuRef540,663,704 - 40,707,894 (-)RGD
CHM1_1540,713,552 - 40,757,967 (-)NCBI
T2T-CHM13v2.0540,967,941 - 41,012,360 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011514003   ⟹   XP_011512305
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38540,711,576 - 40,755,838 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054352255   ⟹   XP_054208230
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0540,967,941 - 41,012,237 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_036514   ⟸   NM_012382
- UniProtKB: B2R6G0 (UniProtKB/Swiss-Prot),   O95105 (UniProtKB/Swiss-Prot),   Q6PID6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011512305   ⟸   XM_011514003
- Peptide Label: isoform X1
- UniProtKB: B2R6G0 (UniProtKB/Swiss-Prot),   O95105 (UniProtKB/Swiss-Prot),   Q6PID6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000490018   ⟸   ENST00000636106
RefSeq Acc Id: ENSP00000490389   ⟸   ENST00000636863
RefSeq Acc Id: ENSP00000490134   ⟸   ENST00000637375
RefSeq Acc Id: ENSP00000338533   ⟸   ENST00000337702
RefSeq Acc Id: XP_054208230   ⟸   XM_054352255
- Peptide Label: isoform X1
- UniProtKB: Q6PID6 (UniProtKB/Swiss-Prot),   B2R6G0 (UniProtKB/Swiss-Prot),   O95105 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6PID6-F1-model_v2 AlphaFold Q6PID6 1-262 view protein structure

Promoters
RGD ID:6869472
Promoter ID:EPDNEW_H7901
Type:initiation region
Name:TTC33_1
Description:tetratricopeptide repeat domain 33
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38540,755,917 - 40,755,977EPDNEW
RGD ID:6803634
Promoter ID:HG_KWN:50022
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000253831,   UC010IVG.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36540,791,481 - 40,791,987 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:29959 AgrOrtholog
COSMIC TTC33 COSMIC
Ensembl Genes ENSG00000113638 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000337702 ENTREZGENE
  ENST00000337702.5 UniProtKB/Swiss-Prot
  ENST00000636106.1 UniProtKB/TrEMBL
  ENST00000636863.1 UniProtKB/TrEMBL
  ENST00000637375.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot
GTEx ENSG00000113638 GTEx
HGNC ID HGNC:29959 ENTREZGENE
Human Proteome Map TTC33 Human Proteome Map
InterPro TPR-like_helical_dom_sf UniProtKB/Swiss-Prot
  TPR_repeat UniProtKB/Swiss-Prot
KEGG Report hsa:23548 UniProtKB/Swiss-Prot
NCBI Gene 23548 ENTREZGENE
PANTHER OSMOSIS RESPONSIVE FACTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TETRATRICOPEPTIDE REPEAT PROTEIN 33 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA162407196 PharmGKB
PROSITE TPR UniProtKB/Swiss-Prot
  TPR_REGION UniProtKB/Swiss-Prot
SMART TPR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot
UniProt A0A1B0GU95_HUMAN UniProtKB/TrEMBL
  A0A1B0GUJ4_HUMAN UniProtKB/TrEMBL
  A0A1B0GV67_HUMAN UniProtKB/TrEMBL
  B2R6G0 ENTREZGENE
  O95105 ENTREZGENE
  Q6PID6 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B2R6G0 UniProtKB/Swiss-Prot
  O95105 UniProtKB/Swiss-Prot