Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | ATOSA | Human | (+)-schisandrin B | multiple interactions | ISO | Atosa (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ATOSA mRNA] | CTD | PMID:31150632 | ATOSA | Human | (1->4)-beta-D-glucan | multiple interactions | ISO | Atosa (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of FAM214A mRNA | CTD | PMID:36331819 | ATOSA | Human | 1-naphthyl isothiocyanate | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of ATOSA mRNA | CTD | PMID:30723492 | ATOSA | Human | 17beta-estradiol | increases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of FAM214A mRNA | CTD | PMID:32145629 | ATOSA | Human | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of ATOSA mRNA | CTD | PMID:31614463 | ATOSA | Human | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | EXP | | 6480464 | Dihydrotestosterone results in increased expression of ATOSA mRNA | CTD | PMID:29581250 | ATOSA | Human | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ATOSA mRNA | CTD | PMID:22298810 | ATOSA | Human | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ATOSA mRNA | CTD | PMID:21215274 and PMID:21724226 | ATOSA | Human | 2-hydroxypropanoic acid | decreases expression | EXP | | 6480464 | Lactic Acid results in decreased expression of ATOSA mRNA | CTD | PMID:30851411 | ATOSA | Human | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of ATOSA mRNA | CTD | PMID:28628672 | ATOSA | Human | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of ATOSA mRNA | CTD | PMID:28628672 | ATOSA | Human | 4,4'-sulfonyldiphenol | decreases expression | ISO | Atosa (Mus musculus) | 6480464 | bisphenol S results in decreased expression of ATOSA mRNA | CTD | PMID:33297965 | ATOSA | Human | 4-hydroxyphenyl retinamide | decreases expression | ISO | Atosa (Mus musculus) | 6480464 | Fenretinide results in decreased expression of ATOSA mRNA | CTD | PMID:28973697 | ATOSA | Human | 6-propyl-2-thiouracil | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of FAM214A mRNA | CTD | PMID:30047161 | ATOSA | Human | acrolein | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ATOSA mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ATOSA mRNA | CTD | PMID:32699268 | ATOSA | Human | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of ATOSA mRNA | CTD | PMID:32763439 | ATOSA | Human | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of ATOSA mRNA | CTD | PMID:21641981 and PMID:27153756 | ATOSA | Human | alpha-pinene | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ATOSA mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ATOSA mRNA | CTD | PMID:32699268 | ATOSA | Human | amitrole | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of FAM214A mRNA | CTD | PMID:30047161 | ATOSA | Human | azoxystrobin | multiple interactions | ISO | Atosa (Rattus norvegicus) | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ATOSA mRNA | CTD | PMID:33854195 | ATOSA | Human | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of ATOSA mRNA | CTD | PMID:21632981 | ATOSA | Human | benzo[b]fluoranthene | increases expression | ISO | Atosa (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of ATOSA mRNA | CTD | PMID:26377693 | ATOSA | Human | bis(2-chloroethyl) sulfide | increases expression | EXP | | 6480464 | Mustard Gas results in increased expression of ATOSA mRNA | CTD | PMID:25102026 | ATOSA | Human | bisphenol A | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of ATOSA mRNA | CTD | PMID:25181051 and PMID:30816183 | ATOSA | Human | bisphenol A | decreases expression | ISO | Atosa (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ATOSA mRNA | CTD | PMID:32156529 | ATOSA | Human | bisphenol A | increases expression | ISO | Atosa (Mus musculus) | 6480464 | bisphenol A results in increased expression of ATOSA mRNA | CTD | PMID:25594700 and PMID:35598803 | ATOSA | Human | butanal | decreases expression | EXP | | 6480464 | butyraldehyde results in decreased expression of ATOSA mRNA | CTD | PMID:26079696 | ATOSA | Human | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATOSA mRNA | CTD | PMID:35301059 | ATOSA | Human | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATOSA mRNA | CTD | PMID:35301059 | ATOSA | Human | carbon nanotube | decreases expression | ISO | Atosa (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | ATOSA | Human | chloroacetaldehyde | decreases expression | EXP | | 6480464 | chloroacetaldehyde results in decreased expression of ATOSA mRNA | CTD | PMID:25596134 | ATOSA | Human | chlorpyrifos | multiple interactions | ISO | Atosa (Rattus norvegicus) | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ATOSA mRNA | CTD | PMID:33854195 | ATOSA | Human | chlorpyrifos | decreases expression | ISO | Atosa (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of ATOSA mRNA | CTD | PMID:32715474 | ATOSA | Human | cidofovir anhydrous | decreases expression | EXP | | 6480464 | Cidofovir results in decreased expression of ATOSA mRNA | CTD | PMID:25596134 | ATOSA | Human | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of ATOSA mRNA | CTD | PMID:25596134 | ATOSA | Human | clodronic acid | decreases expression | EXP | | 6480464 | Clodronic Acid results in decreased expression of ATOSA mRNA | CTD | PMID:25596134 | ATOSA | Human | clofibrate | decreases expression | ISO | Atosa (Mus musculus) | 6480464 | Clofibrate results in decreased expression of ATOSA mRNA | CTD | PMID:23811191 | ATOSA | Human | copper atom | increases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Copper results in increased expression of ATOSA mRNA | CTD | PMID:30556269 | ATOSA | Human | copper(0) | increases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Copper results in increased expression of ATOSA mRNA | CTD | PMID:30556269 | ATOSA | Human | copper(II) sulfate | increases expression | EXP | | 6480464 | Copper Sulfate results in increased expression of ATOSA mRNA | CTD | PMID:19549813 | ATOSA | Human | coumestrol | decreases expression | EXP | | 6480464 | Coumestrol results in decreased expression of ATOSA mRNA | CTD | PMID:19167446 | ATOSA | Human | coumestrol | multiple interactions | EXP | | 6480464 | [Coumestrol co-treated with 2 more ... | CTD | PMID:19167446 | ATOSA | Human | crocidolite asbestos | increases expression | EXP | | 6480464 | Asbestos and Crocidolite results in increased expression of ATOSA mRNA | CTD | PMID:18687144 | ATOSA | Human | crocidolite asbestos | decreases expression | ISO | Atosa (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of ATOSA mRNA | CTD | PMID:29279043 | ATOSA | Human | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of ATOSA mRNA | CTD | PMID:21632981 more ... | ATOSA | Human | dexamethasone | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of ATOSA mRNA | CTD | PMID:28628672 | ATOSA | Human | dexamethasone | increases expression | ISO | Atosa (Mus musculus) | 6480464 | Dexamethasone results in increased expression of ATOSA mRNA | CTD | PMID:22733784 | ATOSA | Human | dioxygen | decreases expression | EXP | | 6480464 | Oxygen deficiency results in decreased expression of ATOSA mRNA | CTD | PMID:25596134 | ATOSA | Human | dioxygen | multiple interactions | ISO | Atosa (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ATOSA mRNA | CTD | PMID:30529165 | ATOSA | Human | diuron | increases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Diuron results in increased expression of ATOSA mRNA | CTD | PMID:25152437 | ATOSA | Human | Enterolactone | multiple interactions | EXP | | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ATOSA mRNA | CTD | PMID:19167446 | ATOSA | Human | ethanol | affects expression | ISO | Atosa (Mus musculus) | 6480464 | Ethanol affects the expression of ATOSA mRNA | CTD | PMID:30319688 | ATOSA | Human | fenofibrate | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Fenofibrate results in decreased expression of ATOSA mRNA | CTD | PMID:25596134 | ATOSA | Human | fenthion | decreases expression | ISO | Atosa (Mus musculus) | 6480464 | Fenthion results in decreased expression of ATOSA mRNA | CTD | PMID:34813904 | ATOSA | Human | fenvalerate | increases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | fenvalerate results in increased expression of ATOSA mRNA | CTD | PMID:30307764 | ATOSA | Human | ferric oxide | increases expression | ISO | Atosa (Mus musculus) | 6480464 | ferric oxide analog results in increased expression of ATOSA mRNA | CTD | PMID:25086211 | ATOSA | Human | flutamide | increases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of ATOSA mRNA | CTD | PMID:24793618 | ATOSA | Human | glafenine | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Glafenine results in decreased expression of ATOSA mRNA | CTD | PMID:24136188 | ATOSA | Human | glyphosate | multiple interactions | ISO | Atosa (Rattus norvegicus) | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ATOSA mRNA | CTD | PMID:33854195 | ATOSA | Human | ifosfamide | decreases expression | EXP | | 6480464 | Ifosfamide results in decreased expression of ATOSA mRNA | CTD | PMID:25596134 | ATOSA | Human | imidacloprid | multiple interactions | ISO | Atosa (Rattus norvegicus) | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ATOSA mRNA | CTD | PMID:33854195 | ATOSA | Human | indometacin | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of ATOSA mRNA | CTD | PMID:28628672 | ATOSA | Human | leflunomide | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Leflunomide results in decreased expression of ATOSA mRNA | CTD | PMID:24136188 | ATOSA | Human | maneb | multiple interactions | ISO | Atosa (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of FAM214A mRNA | CTD | PMID:36117858 | ATOSA | Human | metformin | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Metformin results in decreased expression of ATOSA mRNA | CTD | PMID:25596134 | ATOSA | Human | methapyrilene | increases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Methapyrilene results in increased expression of ATOSA mRNA | CTD | PMID:28935588 | ATOSA | Human | methimazole | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of FAM214A mRNA | CTD | PMID:30047161 | ATOSA | Human | methylparaben | increases expression | EXP | | 6480464 | methylparaben results in increased expression of ATOSA mRNA | CTD | PMID:31745603 | ATOSA | Human | nefazodone | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | nefazodone results in decreased expression of ATOSA mRNA | CTD | PMID:24136188 | ATOSA | Human | nimesulide | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | nimesulide results in decreased expression of ATOSA mRNA | CTD | PMID:24136188 | ATOSA | Human | ozone | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ATOSA mRNA more ... | CTD | PMID:32699268 and PMID:35430440 | ATOSA | Human | paracetamol | multiple interactions | ISO | Atosa (Mus musculus) | 6480464 | PANX1 gene mutant form promotes the reaction [Acetaminophen results in decreased expression of ATOSA mRNA] | CTD | PMID:29246445 | ATOSA | Human | paracetamol | decreases expression | ISO | Atosa (Mus musculus) | 6480464 | Acetaminophen results in decreased expression of ATOSA mRNA | CTD | PMID:19420014 and PMID:29246445 | ATOSA | Human | paraquat | multiple interactions | ISO | Atosa (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of FAM214A mRNA | CTD | PMID:36117858 | ATOSA | Human | perfluorooctane-1-sulfonic acid | decreases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in decreased expression of ATOSA mRNA | CTD | PMID:27153767 | ATOSA | Human | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Atosa (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of FAM214A mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of FAM214A mRNA | CTD | PMID:36331819 | ATOSA | Human | pirinixic acid | decreases expression | ISO | Atosa (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of ATOSA mRNA | CTD | PMID:23811191 | ATOSA | Human | potassium chromate | decreases expression | EXP | | 6480464 | potassium chromate(VI) results in decreased expression of ATOSA mRNA | CTD | PMID:22714537 | ATOSA | Human | rac-lactic acid | decreases expression | EXP | | 6480464 | Lactic Acid results in decreased expression of ATOSA mRNA | CTD | PMID:30851411 | ATOSA | Human | resveratrol | multiple interactions | EXP | | 6480464 | [Coumestrol co-treated with Resveratrol] results in decreased expression of ATOSA mRNA | CTD | PMID:19167446 | ATOSA | Human | rotenone | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Rotenone results in decreased expression of ATOSA mRNA | CTD | PMID:28374803 | ATOSA | Human | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide analog results in decreased expression of ATOSA mRNA | CTD | PMID:25895662 | ATOSA | Human | sodium arsenite | affects expression | EXP | | 6480464 | sodium arsenite affects the expression of ATOSA mRNA | CTD | PMID:34032870 | ATOSA | Human | sodium dichromate | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | sodium bichromate results in decreased expression of ATOSA mRNA | CTD | PMID:25993096 | ATOSA | Human | sulfadimethoxine | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of FAM214A mRNA | CTD | PMID:30047161 | ATOSA | Human | tetrachloromethane | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of ATOSA mRNA | CTD | PMID:31150632 | ATOSA | Human | tetrachloromethane | decreases expression | ISO | Atosa (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of ATOSA mRNA | CTD | PMID:27339419 and PMID:31919559 | ATOSA | Human | tetrachloromethane | multiple interactions | ISO | Atosa (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ATOSA mRNA] | CTD | PMID:31150632 | ATOSA | Human | tetraphene | increases expression | ISO | Atosa (Mus musculus) | 6480464 | benz(a)anthracene results in increased expression of ATOSA mRNA | CTD | PMID:26377693 | ATOSA | Human | thiabendazole | multiple interactions | ISO | Atosa (Rattus norvegicus) | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ATOSA mRNA | CTD | PMID:33854195 | ATOSA | Human | titanium dioxide | increases expression | ISO | Atosa (Mus musculus) | 6480464 | titanium dioxide results in increased expression of ATOSA mRNA | CTD | PMID:29264374 | ATOSA | Human | trichostatin A | affects expression | EXP | | 6480464 | trichostatin A affects the expression of ATOSA mRNA | CTD | PMID:28542535 | ATOSA | Human | triptonide | increases expression | ISO | Atosa (Mus musculus) | 6480464 | triptonide results in increased expression of ATOSA mRNA | CTD | PMID:33045310 | ATOSA | Human | urethane | increases expression | EXP | | 6480464 | Urethane results in increased expression of ATOSA mRNA | CTD | PMID:28818685 | ATOSA | Human | vinclozolin | increases methylation | ISO | Atosa (Rattus norvegicus) | 6480464 | vinclozolin results in increased methylation of ATOSA gene | CTD | PMID:31682807 | ATOSA | Human | zinc atom | multiple interactions | ISO | Atosa (Rattus norvegicus) | 6480464 | Zinc inhibits the reaction [Zinc deficiency results in decreased expression of ATOSA mRNA] | CTD | PMID:16140947 | ATOSA | Human | zinc atom | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Zinc deficiency results in decreased expression of ATOSA mRNA | CTD | PMID:16140947 | ATOSA | Human | zinc(0) | multiple interactions | ISO | Atosa (Rattus norvegicus) | 6480464 | Zinc inhibits the reaction [Zinc deficiency results in decreased expression of ATOSA mRNA] | CTD | PMID:16140947 | ATOSA | Human | zinc(0) | decreases expression | ISO | Atosa (Rattus norvegicus) | 6480464 | Zinc deficiency results in decreased expression of ATOSA mRNA | CTD | PMID:16140947 | ATOSA | Human | zoledronic acid | increases expression | EXP | | 6480464 | Zoledronic Acid results in increased expression of ATOSA mRNA | CTD | PMID:25596134 | |
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Gene Ontology Annotations Click to see Annotation Detail View
Cellular Component
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Imported Human Phenotype Annotations - ClinVar
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Phenotype Annotations
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:10718198 | PMID:12477932 | PMID:14702039 | PMID:16344560 | PMID:20936779 | PMID:22990118 | PMID:25416956 | PMID:26760575 | PMID:32513696 | PMID:35319107 | PMID:38113892 |
Genomics
Comparative Map Data
| ATOSA (Homo sapiens - human) |
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| Atosa (Mus musculus - house mouse) |
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| Atosa (Rattus norvegicus - Norway rat) |
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| Atosa (Chinchilla lanigera - long-tailed chinchilla) |
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| ATOSA (Pan paniscus - bonobo/pygmy chimpanzee) |
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| ATOSA (Canis lupus familiaris - dog) |
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| Atosa (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| ATOSA (Sus scrofa - pig) |
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| ATOSA (Chlorocebus sabaeus - green monkey) |
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| Atosa (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in ATOSA
18 total Variants 
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