CCDC59 (coiled-coil domain containing 59) - Rat Genome Database

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Gene: CCDC59 (coiled-coil domain containing 59) Homo sapiens
Analyze
Symbol: CCDC59
Name: coiled-coil domain containing 59
RGD ID: 1606017
HGNC Page HGNC:25005
Description: Enables RNA binding activity. Predicted to be located in nucleoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BR22; coiled-coil domain-containing protein 59; DKFZp686K1021; FLJ10294; HSPC128; TAP26; thyroid transcription factor 1-associated protein 26; TTF-1-associated protein 26; TTF-1-associated protein BR2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: LOC100288028   LOC729496  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381282,352,303 - 82,358,805 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1282,223,681 - 82,358,805 (-)EnsemblGRCh38hg38GRCh38
GRCh371282,746,082 - 82,752,584 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361281,270,220 - 81,276,330 (-)NCBINCBI36Build 36hg18NCBI36
Celera1282,413,647 - 82,420,144 (-)NCBICelera
Cytogenetic Map12q21.31NCBI
HuRef1279,803,324 - 79,809,821 (-)NCBIHuRef
CHM1_11282,711,940 - 82,718,437 (-)NCBICHM1_1
T2T-CHM13v2.01282,331,767 - 82,338,265 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (TAS)
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8125298   PMID:11042152   PMID:11152647   PMID:12477932   PMID:12882447   PMID:14702039   PMID:16341674   PMID:16344560   PMID:16630564   PMID:17207965   PMID:17353931   PMID:21244100  
PMID:21832049   PMID:22658674   PMID:23455922   PMID:24778252   PMID:25108383   PMID:25281560   PMID:25544563   PMID:25609649   PMID:26186194   PMID:27025967   PMID:27609421   PMID:27926873  
PMID:28514442   PMID:28533407   PMID:29509190   PMID:31091453   PMID:31182584   PMID:31527615   PMID:32296183   PMID:33729478   PMID:33961781   PMID:34079125   PMID:34133714   PMID:34373451  
PMID:35013218   PMID:35140242   PMID:35271311   PMID:35384245   PMID:35864588   PMID:35944360   PMID:36244648   PMID:36574265   PMID:36912080   PMID:37616343  


Genomics

Comparative Map Data
CCDC59
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381282,352,303 - 82,358,805 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1282,223,681 - 82,358,805 (-)EnsemblGRCh38hg38GRCh38
GRCh371282,746,082 - 82,752,584 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361281,270,220 - 81,276,330 (-)NCBINCBI36Build 36hg18NCBI36
Celera1282,413,647 - 82,420,144 (-)NCBICelera
Cytogenetic Map12q21.31NCBI
HuRef1279,803,324 - 79,809,821 (-)NCBIHuRef
CHM1_11282,711,940 - 82,718,437 (-)NCBICHM1_1
T2T-CHM13v2.01282,331,767 - 82,338,265 (-)NCBIT2T-CHM13v2.0
Ccdc59
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910105,677,340 - 105,683,371 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10105,676,928 - 105,683,694 (+)EnsemblGRCm39 Ensembl
GRCm3810105,841,479 - 105,847,510 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10105,841,067 - 105,847,833 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710105,278,535 - 105,284,566 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610105,245,589 - 105,251,620 (+)NCBIMGSCv36mm8
Celera10107,790,826 - 107,796,856 (+)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1055.12NCBI
Ccdc59
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8743,029,272 - 43,035,655 (+)NCBIGRCr8
mRatBN7.2741,142,760 - 41,149,143 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl741,142,760 - 41,149,143 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx743,042,448 - 43,048,836 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0745,245,512 - 45,251,900 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0744,999,901 - 45,006,288 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0747,928,138 - 47,934,690 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl747,928,060 - 47,934,929 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0747,942,423 - 47,948,975 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4744,496,241 - 44,502,624 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1744,516,930 - 44,522,810 (+)NCBI
Celera738,018,929 - 38,025,316 (+)NCBICelera
Cytogenetic Map7q21NCBI
Ccdc59
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540520,731,464 - 20,738,657 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540520,732,649 - 20,738,678 (-)NCBIChiLan1.0ChiLan1.0
CCDC59
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21090,396,588 - 90,402,652 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11290,392,986 - 90,399,103 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01279,864,105 - 79,873,182 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11282,976,079 - 82,981,650 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1282,976,079 - 82,981,650 (-)Ensemblpanpan1.1panPan2
CCDC59
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11524,364,510 - 24,373,567 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1524,364,779 - 24,373,419 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1524,795,481 - 24,804,911 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01524,743,406 - 24,752,836 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1524,743,676 - 24,752,295 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11524,320,972 - 24,330,182 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01524,369,767 - 24,379,043 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01524,610,635 - 24,620,062 (-)NCBIUU_Cfam_GSD_1.0
Ccdc59
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494535,897,608 - 35,905,140 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936507330,481 - 337,906 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936507330,481 - 337,810 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCDC59
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl599,358,330 - 99,364,091 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1599,358,726 - 99,364,092 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25104,173,569 - 104,178,937 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCDC59
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_023666037167,593,487 - 167,599,644 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccdc59
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248371,686,109 - 1,693,423 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248371,687,403 - 1,693,619 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCDC59
23 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 12q21.31(chr12:80266605-85253555)x1 copy number loss See cases [RCV000051315] Chr12:80266605..85253555 [GRCh38]
Chr12:80660385..85647333 [GRCh37]
Chr12:79184516..84171464 [NCBI36]
Chr12:12q21.31		 pathogenic
GRCh38/hg38 12q21.2-21.31(chr12:77564757-85370822)x3 copy number gain See cases [RCV000053684] Chr12:77564757..85370822 [GRCh38]
Chr12:77958537..85764600 [GRCh37]
Chr12:76482668..84288731 [NCBI36]
Chr12:12q21.2-21.31		 pathogenic
NM_032230.3(METTL25):c.208G>A (p.Glu70Lys) single nucleotide variant not provided [RCV000122574] Chr12:82358773 [GRCh38]
Chr12:82752552 [GRCh37]
Chr12:12q21.31		 uncertain significance
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33		 pathogenic
GRCh38/hg38 12q21.1-22(chr12:73485697-92795805)x1 copy number loss See cases [RCV000143099] Chr12:73485697..92795805 [GRCh38]
Chr12:73879477..93189581 [GRCh37]
Chr12:72165744..91713712 [NCBI36]
Chr12:12q21.1-22		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic|likely pathogenic
GRCh37/hg19 12q21.31(chr12:82315146-83005702)x1 copy number loss See cases [RCV000447985] Chr12:82315146..83005702 [GRCh37]
Chr12:12q21.31		 uncertain significance
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12q21.31(chr12:81666797-82808748)x3 copy number gain not provided [RCV000683459] Chr12:81666797..82808748 [GRCh37]
Chr12:12q21.31		 uncertain significance
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3 copy number gain not provided [RCV000750253] Chr12:621220..133779118 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12q15-21.33(chr12:69608090-89629345)x1 copy number loss not provided [RCV000737927] Chr12:69608090..89629345 [GRCh37]
Chr12:12q15-21.33		 pathogenic
GRCh37/hg19 12q21.31-21.32(chr12:82183041-88755577) copy number gain not provided [RCV000767570] Chr12:82183041..88755577 [GRCh37]
Chr12:12q21.31-21.32		 pathogenic
GRCh37/hg19 12q21.2-22(chr12:77737623-94330526)x1 copy number loss not provided [RCV000848027] Chr12:77737623..94330526 [GRCh37]
Chr12:12q21.2-22		 pathogenic
NM_014167.5(CCDC59):c.13A>G (p.Arg5Gly) single nucleotide variant not specified [RCV004302325] Chr12:82358364 [GRCh38]
Chr12:82752143 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_014167.5(CCDC59):c.45T>G (p.Ile15Met) single nucleotide variant not specified [RCV004326908] Chr12:82358332 [GRCh38]
Chr12:82752111 [GRCh37]
Chr12:12q21.31		 uncertain significance
GRCh37/hg19 12q21.31(chr12:82315146-83005702) copy number loss not specified [RCV002053004] Chr12:82315146..83005702 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_014167.5(CCDC59):c.393C>G (p.Asp131Glu) single nucleotide variant not specified [RCV004200555] Chr12:82357031 [GRCh38]
Chr12:82750810 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_014167.5(CCDC59):c.182T>A (p.Leu61Gln) single nucleotide variant not specified [RCV004210660] Chr12:82357242 [GRCh38]
Chr12:82751021 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_032230.3(METTL25):c.172G>A (p.Val58Met) single nucleotide variant not specified [RCV004157040] Chr12:82358737 [GRCh38]
Chr12:82752516 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_014167.5(CCDC59):c.31C>T (p.Arg11Trp) single nucleotide variant not specified [RCV004102457] Chr12:82358346 [GRCh38]
Chr12:82752125 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_014167.5(CCDC59):c.148C>T (p.Arg50Cys) single nucleotide variant not specified [RCV004234926] Chr12:82358229 [GRCh38]
Chr12:82752008 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_032230.3(METTL25):c.125A>G (p.Tyr42Cys) single nucleotide variant not specified [RCV004120903] Chr12:82358690 [GRCh38]
Chr12:82752469 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_014167.5(CCDC59):c.565G>A (p.Glu189Lys) single nucleotide variant not specified [RCV004156739] Chr12:82353312 [GRCh38]
Chr12:82747091 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_032230.3(METTL25):c.196G>A (p.Ala66Thr) single nucleotide variant not specified [RCV004152096] Chr12:82358761 [GRCh38]
Chr12:82752540 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_032230.3(METTL25):c.182C>G (p.Ala61Gly) single nucleotide variant not specified [RCV004155162] Chr12:82358747 [GRCh38]
Chr12:82752526 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_014167.5(CCDC59):c.688A>G (p.Met230Val) single nucleotide variant not specified [RCV004168881] Chr12:82353189 [GRCh38]
Chr12:82746968 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_014167.5(CCDC59):c.278T>C (p.Leu93Pro) single nucleotide variant not specified [RCV004115977] Chr12:82357146 [GRCh38]
Chr12:82750925 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_014167.5(CCDC59):c.713A>C (p.Gln238Pro) single nucleotide variant not specified [RCV004160458] Chr12:82353164 [GRCh38]
Chr12:82746943 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_014167.5(CCDC59):c.16C>G (p.Arg6Gly) single nucleotide variant not specified [RCV004178832] Chr12:82358361 [GRCh38]
Chr12:82752140 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_032230.3(METTL25):c.16C>T (p.Pro6Ser) single nucleotide variant not specified [RCV004135312] Chr12:82358581 [GRCh38]
Chr12:82752360 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_032230.3(METTL25):c.95C>G (p.Ser32Cys) single nucleotide variant not specified [RCV004081323] Chr12:82358660 [GRCh38]
Chr12:82752439 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_032230.3(METTL25):c.128C>T (p.Thr43Ile) single nucleotide variant not specified [RCV004353791] Chr12:82358693 [GRCh38]
Chr12:82752472 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_032230.3(METTL25):c.5C>T (p.Ala2Val) single nucleotide variant not specified [RCV004344759] Chr12:82358570 [GRCh38]
Chr12:82752349 [GRCh37]
Chr12:12q21.31		 uncertain significance
GRCh37/hg19 12q21.31(chr12:82424439-83222097)x4 copy number gain not provided [RCV003485362] Chr12:82424439..83222097 [GRCh37]
Chr12:12q21.31		 uncertain significance
GRCh37/hg19 12q21.31(chr12:80647969-85713707)x1 copy number loss not provided [RCV003483158] Chr12:80647969..85713707 [GRCh37]
Chr12:12q21.31		 uncertain significance
GRCh37/hg19 12q21.1-21.33(chr12:74887087-90469800)x1 copy number loss not specified [RCV003986972] Chr12:74887087..90469800 [GRCh37]
Chr12:12q21.1-21.33		 pathogenic
NM_032230.3(METTL25):c.37C>G (p.Leu13Val) single nucleotide variant not specified [RCV004424370] Chr12:82358602 [GRCh38]
Chr12:82752381 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_032230.3(METTL25):c.151G>C (p.Val51Leu) single nucleotide variant not specified [RCV004424366] Chr12:82358716 [GRCh38]
Chr12:82752495 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_014167.5(CCDC59):c.34C>T (p.Pro12Ser) single nucleotide variant not specified [RCV004427569] Chr12:82358343 [GRCh38]
Chr12:82752122 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_014167.5(CCDC59):c.586G>C (p.Glu196Gln) single nucleotide variant not specified [RCV004427570] Chr12:82353291 [GRCh38]
Chr12:82747070 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_032230.3(METTL25):c.181G>T (p.Ala61Ser) single nucleotide variant not specified [RCV004340105] Chr12:82358746 [GRCh38]
Chr12:82752525 [GRCh37]
Chr12:12q21.31		 uncertain significance
NM_014167.5(CCDC59):c.698T>G (p.Leu233Arg) single nucleotide variant not specified [RCV004313059] Chr12:82353179 [GRCh38]
Chr12:82746958 [GRCh37]
Chr12:12q21.31		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:870
Count of miRNA genes:520
Interacting mature miRNAs:577
Transcripts:ENST00000256151, ENST00000547758, ENST00000548126, ENST00000550589, ENST00000552377, ENST00000552412, ENST00000552606
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
STS-T48329  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376149,812,857 - 149,813,018UniSTSGRCh37
Build 366149,854,550 - 149,854,711RGDNCBI36
Celera6150,547,949 - 150,548,110RGD
Cytogenetic Map12q21.31UniSTS
Cytogenetic Map6q25.1UniSTS
HuRef6147,379,564 - 147,379,725UniSTS
GeneMap99-GB4 RH Map6596.91UniSTS
RH98258  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371282,750,866 - 82,751,047UniSTSGRCh37
Build 361281,274,997 - 81,275,178RGDNCBI36
Celera1282,418,429 - 82,418,610RGD
Cytogenetic Map12q21.31UniSTS
HuRef1279,808,106 - 79,808,287UniSTS
GeneMap99-GB4 RH Map12326.68UniSTS
RH118666  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371282,751,473 - 82,751,802UniSTSGRCh37
Build 361281,275,604 - 81,275,933RGDNCBI36
Celera1282,419,033 - 82,419,362RGD
Cytogenetic Map12q21.31UniSTS
HuRef1279,808,710 - 79,809,039UniSTS
TNG Radiation Hybrid Map1236618.0UniSTS
HSPC128_9574  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371282,746,477 - 82,747,035UniSTSGRCh37
Build 361281,270,608 - 81,271,166RGDNCBI36
Celera1282,414,041 - 82,414,599RGD
HuRef1279,803,718 - 79,804,276UniSTS
SHGC-56799  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371282,746,719 - 82,746,872UniSTSGRCh37
GRCh376149,812,491 - 149,812,645UniSTSGRCh37
Build 366149,854,184 - 149,854,338RGDNCBI36
Celera6150,547,583 - 150,547,737RGD
Celera1282,414,283 - 82,414,436UniSTS
Cytogenetic Map6q25.1UniSTS
Cytogenetic Map12q21.31UniSTS
HuRef1279,803,960 - 79,804,113UniSTS
HuRef6147,379,198 - 147,379,352UniSTS
TNG Radiation Hybrid Map1236452.0UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2280 1746 1376 310 1256 159 4040 1597 2361 298 1429 1600 165 1203 2517 4 1
Low 159 1245 350 314 695 306 317 600 1373 121 31 13 10 1 1 271 2 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000256151   ⟹   ENSP00000256151
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1282,352,303 - 82,358,387 (-)Ensembl
RefSeq Acc Id: ENST00000547758
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1282,356,844 - 82,358,805 (-)Ensembl
RefSeq Acc Id: ENST00000548126
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1282,352,847 - 82,358,786 (-)Ensembl
RefSeq Acc Id: ENST00000550589
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1282,352,839 - 82,356,121 (-)Ensembl
RefSeq Acc Id: ENST00000552377   ⟹   ENSP00000450183
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1282,223,681 - 82,358,396 (-)Ensembl
RefSeq Acc Id: ENST00000552412
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1282,357,115 - 82,358,292 (-)Ensembl
RefSeq Acc Id: ENST00000552606
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1282,356,857 - 82,358,409 (-)Ensembl
RefSeq Acc Id: NM_014167   ⟹   NP_054886
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381282,352,303 - 82,358,387 (-)NCBI
GRCh371282,746,083 - 82,752,584 (-)RGD
Build 361281,270,220 - 81,276,330 (-)NCBI Archive
Celera1282,413,647 - 82,420,144 (-)RGD
HuRef1279,803,324 - 79,809,821 (-)ENTREZGENE
CHM1_11282,711,940 - 82,718,052 (-)NCBI
T2T-CHM13v2.01282,331,767 - 82,337,847 (-)NCBI
Sequence:
RefSeq Acc Id: NR_033192
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381282,352,304 - 82,358,805 (-)NCBI
GRCh371282,746,083 - 82,752,584 (-)RGD
Celera1282,413,647 - 82,420,144 (-)RGD
HuRef1279,803,324 - 79,809,821 (-)ENTREZGENE
CHM1_11282,711,940 - 82,718,437 (-)NCBI
T2T-CHM13v2.01282,331,768 - 82,338,265 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_054886   ⟸   NM_014167
- UniProtKB: Q9H2V5 (UniProtKB/Swiss-Prot),   Q9NW62 (UniProtKB/Swiss-Prot),   Q9P031 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000256151   ⟸   ENST00000256151
RefSeq Acc Id: ENSP00000450183   ⟸   ENST00000552377

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9P031-F1-model_v2 AlphaFold Q9P031 1-241 view protein structure

Promoters
RGD ID:6789776
Promoter ID:HG_KWN:16246
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562
Transcripts:NM_014167,   NR_033192
Position:
Human AssemblyChrPosition (strand)Source
Build 361281,276,256 - 81,276,922 (-)MPROMDB
RGD ID:7224921
Promoter ID:EPDNEW_H18206
Type:initiation region
Name:CCDC59_1
Description:coiled-coil domain containing 59
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H18208  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381282,358,387 - 82,358,447EPDNEW
RGD ID:7224925
Promoter ID:EPDNEW_H18208
Type:initiation region
Name:CCDC59_2
Description:coiled-coil domain containing 59
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H18206  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381282,358,775 - 82,358,835EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:25005 AgrOrtholog
COSMIC CCDC59 COSMIC
Ensembl Genes ENSG00000133773 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000256151 ENTREZGENE
  ENST00000256151.8 UniProtKB/Swiss-Prot
  ENST00000552377.5 UniProtKB/TrEMBL
GTEx ENSG00000133773 GTEx
HGNC ID HGNC:25005 ENTREZGENE
Human Proteome Map CCDC59 Human Proteome Map
InterPro Fyv7/TAP26 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:29080 UniProtKB/Swiss-Prot
NCBI Gene 29080 ENTREZGENE
OMIM 619280 OMIM
PANTHER PTHR15657 UniProtKB/Swiss-Prot
  THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam rRNA_processing UniProtKB/Swiss-Prot
PharmGKB PA143485412 PharmGKB
PRINTS BR22PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt F8VNY5_HUMAN UniProtKB/TrEMBL
  Q9H2V5 ENTREZGENE
  Q9NW62 ENTREZGENE
  Q9P031 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q9H2V5 UniProtKB/Swiss-Prot
  Q9NW62 UniProtKB/Swiss-Prot