Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | She (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | ISO | She (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:27291303 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | She (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | She (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SHE mRNA | CTD | PMID:15328365 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | She (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SHE mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | She (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SHE mRNA | CTD | PMID:22298810 | 4,4'-sulfonyldiphenol | increases expression | ISO | She (Mus musculus) | 6480464 | bisphenol S results in increased expression of SHE mRNA | CTD | PMID:30951980 | 4,4'-sulfonyldiphenol | increases methylation | ISO | She (Mus musculus) | 6480464 | bisphenol S results in increased methylation of SHE exon | CTD | PMID:33297965 | 4-hydroxyphenyl retinamide | increases expression | ISO | She (Mus musculus) | 6480464 | Fenretinide results in increased expression of SHE mRNA | CTD | PMID:28973697 | 5-aza-2'-deoxycytidine | affects expression | EXP | | 6480464 | Decitabine affects the expression of SHE mRNA | CTD | PMID:23300844 | acrylamide | decreases expression | ISO | She (Rattus norvegicus) | 6480464 | Acrylamide results in decreased expression of SHE mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases methylation | EXP | | 6480464 | Aflatoxin B1 results in increased methylation of SHE intron | CTD | PMID:30157460 | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of SHE mRNA | CTD | PMID:21934132 | amphetamine | decreases expression | ISO | She (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of SHE mRNA | CTD | PMID:30779732 | arsane | decreases expression | ISO | She (Mus musculus) | 6480464 | Arsenic results in decreased expression of SHE mRNA | CTD | PMID:19654921 | arsenic atom | decreases expression | ISO | She (Mus musculus) | 6480464 | Arsenic results in decreased expression of SHE mRNA | CTD | PMID:19654921 | benzo[a]pyrene | increases expression | ISO | She (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of SHE mRNA | CTD | PMID:32417428 | bisphenol A | increases expression | ISO | She (Mus musculus) | 6480464 | bisphenol A results in increased expression of SHE mRNA | CTD | PMID:26063408 and PMID:30951980 | bisphenol A | affects expression | ISO | She (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of SHE mRNA | CTD | PMID:25181051 | bisphenol F | increases expression | ISO | She (Mus musculus) | 6480464 | bisphenol F results in increased expression of SHE mRNA | CTD | PMID:30951980 | calcitriol | increases expression | EXP | | 6480464 | Calcitriol results in increased expression of SHE mRNA | CTD | PMID:16002434 and PMID:26485663 | carbon nanotube | decreases expression | ISO | She (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SHE gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | ISO | She (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of SHE mRNA | CTD | PMID:37019170 | cisplatin | affects expression | EXP | | 6480464 | Cisplatin affects the expression of SHE mRNA | CTD | PMID:23300844 | copper atom | increases expression | ISO | She (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of SHE mRNA | CTD | PMID:26033743 | copper(0) | increases expression | ISO | She (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of SHE mRNA | CTD | PMID:26033743 | decabromodiphenyl ether | increases expression | ISO | She (Rattus norvegicus) | 6480464 | decabromobiphenyl ether results in increased expression of SHE mRNA | CTD | PMID:23640034 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SHE mRNA | CTD | PMID:27188386 | entinostat | increases expression | EXP | | 6480464 | entinostat results in increased expression of SHE mRNA | CTD | PMID:26272509 and PMID:27188386 | entinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SHE mRNA | CTD | PMID:27188386 | folic acid | decreases expression | ISO | She (Mus musculus) | 6480464 | Folic Acid results in decreased expression of SHE mRNA | CTD | PMID:25629700 | ozone | multiple interactions | ISO | She (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of SHE mRNA | CTD | PMID:34911549 | paracetamol | decreases expression | ISO | She (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of SHE mRNA | CTD | PMID:33387578 | PCB138 | multiple interactions | ISO | She (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | pioglitazone | multiple interactions | ISO | She (Mus musculus) | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SHE mRNA | CTD | PMID:27935865 | potassium dichromate | decreases expression | ISO | She (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of SHE mRNA | CTD | PMID:23608068 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SHE mRNA | CTD | PMID:27188386 | sodium arsenate | increases expression | ISO | She (Mus musculus) | 6480464 | sodium arsenate results in increased expression of SHE mRNA | CTD | PMID:30953684 | sulforaphane | decreases expression | ISO | She (Mus musculus) | 6480464 | sulforaphane results in decreased expression of SHE mRNA | CTD | PMID:30529165 | titanium dioxide | decreases expression | ISO | She (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of SHE mRNA | CTD | PMID:29264374 | trichloroethene | increases expression | ISO | She (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of SHE mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | EXP | | 6480464 | trichostatin A results in increased expression of SHE mRNA | CTD | PMID:24935251 | trimellitic anhydride | decreases expression | ISO | She (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of SHE mRNA | CTD | PMID:19042947 | triptonide | increases expression | ISO | She (Mus musculus) | 6480464 | triptonide results in increased expression of SHE mRNA | CTD | PMID:33045310 | valproic acid | affects expression | ISO | She (Mus musculus) | 6480464 | Valproic Acid affects the expression of SHE mRNA | CTD | PMID:17292431 | valproic acid | increases methylation | EXP | | 6480464 | Valproic Acid results in increased methylation of SHE gene | CTD | PMID:29154799 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of SHE mRNA | CTD | PMID:23179753 more ... | |