RGS13 (regulator of G protein signaling 13) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: RGS13 (regulator of G protein signaling 13) Homo sapiens
Analyze
Symbol: RGS13
Name: regulator of G protein signaling 13
RGD ID: 1604849
HGNC Page HGNC:9995
Description: Predicted to enable GTPase activity. Predicted to be involved in negative regulation of signal transduction. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and negative regulation of G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: MGC17173; regulator of G-protein signaling 13; regulator of G-protein signalling 13
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381192,636,147 - 192,660,311 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1192,636,138 - 192,660,311 (+)EnsemblGRCh38hg38GRCh38
GRCh371192,605,277 - 192,629,441 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361190,871,905 - 190,896,013 (+)NCBINCBI36Build 36hg18NCBI36
Celera1165,715,071 - 165,739,113 (+)NCBICelera
Cytogenetic Map1q31.2NCBI
HuRef1163,841,268 - 163,865,380 (+)NCBIHuRef
CHM1_11194,027,097 - 194,051,266 (+)NCBICHM1_1
T2T-CHM13v2.01191,983,284 - 192,007,378 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)
nucleus  (IEA)
plasma membrane  (IEA,TAS)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8602223   PMID:11829488   PMID:11875076   PMID:12193720   PMID:12477932   PMID:12970790   PMID:15489334   PMID:16565322   PMID:16710414   PMID:19017978   PMID:20468064   PMID:20627871  
PMID:20974683   PMID:21531726   PMID:22199357   PMID:28514442   PMID:30308012   PMID:32296183   PMID:33961781   PMID:35156780   PMID:35256949   PMID:36217030  


Genomics

Comparative Map Data
RGS13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381192,636,147 - 192,660,311 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1192,636,138 - 192,660,311 (+)EnsemblGRCh38hg38GRCh38
GRCh371192,605,277 - 192,629,441 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361190,871,905 - 190,896,013 (+)NCBINCBI36Build 36hg18NCBI36
Celera1165,715,071 - 165,739,113 (+)NCBICelera
Cytogenetic Map1q31.2NCBI
HuRef1163,841,268 - 163,865,380 (+)NCBIHuRef
CHM1_11194,027,097 - 194,051,266 (+)NCBICHM1_1
T2T-CHM13v2.01191,983,284 - 192,007,378 (+)NCBIT2T-CHM13v2.0
Rgs13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391144,013,083 - 144,053,240 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1144,014,392 - 144,053,110 (-)EnsemblGRCm39 Ensembl
GRCm381144,137,386 - 144,177,372 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1144,138,654 - 144,177,372 (-)EnsemblGRCm38mm10GRCm38
MGSCv371145,985,797 - 146,024,502 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361145,900,885 - 145,939,590 (-)NCBIMGSCv36mm8
Celera1146,698,430 - 146,735,959 (-)NCBICelera
Cytogenetic Map1FNCBI
cM Map162.56NCBI
Rgs13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81358,472,604 - 58,505,922 (-)NCBIGRCr8
mRatBN7.21355,922,290 - 55,955,753 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1355,922,395 - 55,955,648 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01360,970,172 - 61,004,260 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1360,970,247 - 61,003,744 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01365,957,018 - 65,989,542 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41358,016,245 - 58,042,762 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1355,997,004 - 56,031,895 (-)NCBICelera
Cytogenetic Map13q21NCBI
Rgs13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540630,111,760 - 30,135,283 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540630,111,770 - 30,134,605 (+)NCBIChiLan1.0ChiLan1.0
RGS13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2157,128,862 - 57,152,921 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1156,791,844 - 56,815,911 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01168,073,338 - 168,124,215 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11172,395,240 - 172,419,307 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1172,395,240 - 172,419,307 (+)Ensemblpanpan1.1panPan2
RGS13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1386,291,146 - 6,316,662 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl386,291,182 - 6,315,198 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha386,385,503 - 6,413,908 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0386,305,783 - 6,334,197 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl386,308,730 - 6,334,213 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1386,304,512 - 6,332,968 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0386,670,204 - 6,698,602 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0386,905,903 - 6,934,312 (-)NCBIUU_Cfam_GSD_1.0
Rgs13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934481,181,016 - 81,210,806 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936638940,677 - 963,585 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936638940,691 - 963,585 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl101,057,622 - 1,082,222 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1101,056,920 - 1,082,394 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2102,695,589 - 2,702,748 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RGS13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12536,775,602 - 36,802,311 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2536,776,345 - 36,791,180 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605537,725,660 - 37,749,745 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rgs13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624814916,732 - 931,380 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624814914,509 - 1,012,924 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RGS13
8 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1q31.1-42.11(chr1:187143981-224299417)x3 copy number gain See cases [RCV000051857] Chr1:187143981..224299417 [GRCh38]
Chr1:187113113..224487119 [GRCh37]
Chr1:185379736..222553742 [NCBI36]
Chr1:1q31.1-42.11		 pathogenic
GRCh38/hg38 1q31.2(chr1:192567876-193180049)x1 copy number loss See cases [RCV000053950] Chr1:192567876..193180049 [GRCh38]
Chr1:192537006..193149179 [GRCh37]
Chr1:190803629..191415802 [NCBI36]
Chr1:1q31.2		 pathogenic
GRCh38/hg38 1q25.2-32.1(chr1:179032905-199724897)x1 copy number loss See cases [RCV000053948] Chr1:179032905..199724897 [GRCh38]
Chr1:179002040..199694025 [GRCh37]
Chr1:177268663..197960648 [NCBI36]
Chr1:1q25.2-32.1		 pathogenic
GRCh38/hg38 1q25.2-31.3(chr1:176595962-196301688)x1 copy number loss See cases [RCV000134144] Chr1:176595962..196301688 [GRCh38]
Chr1:176565098..196270818 [GRCh37]
Chr1:174831721..194537441 [NCBI36]
Chr1:1q25.2-31.3		 pathogenic
GRCh38/hg38 1q31.1-32.1(chr1:189034483-199615866)x1 copy number loss See cases [RCV000135590] Chr1:189034483..199615866 [GRCh38]
Chr1:189003614..199584994 [GRCh37]
Chr1:187270237..197851617 [NCBI36]
Chr1:1q31.1-32.1		 pathogenic
GRCh37/hg19 1q25.2-32.1(chr1:179413479-201764737)x1 copy number loss See cases [RCV000445748] Chr1:179413479..201764737 [GRCh37]
Chr1:1q25.2-32.1		 pathogenic
GRCh37/hg19 1q25.2-32.1(chr1:179073386-200192265)x1 copy number loss See cases [RCV000448809] Chr1:179073386..200192265 [GRCh37]
Chr1:1q25.2-32.1		 pathogenic
GRCh37/hg19 1q24.3-31.3(chr1:171990029-195086758)x1 copy number loss See cases [RCV000448686] Chr1:171990029..195086758 [GRCh37]
Chr1:1q24.3-31.3		 pathogenic
GRCh37/hg19 1q25.2-32.1(chr1:179011314-199022759)x1 copy number loss See cases [RCV000512128] Chr1:179011314..199022759 [GRCh37]
Chr1:1q25.2-32.1		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
NM_002927.5(RGS13):c.436T>C (p.Tyr146His) single nucleotide variant not specified [RCV004288652] Chr1:192659479 [GRCh38]
Chr1:192628609 [GRCh37]
Chr1:1q31.2		 uncertain significance
Single allele deletion Hyperparathyroidism 1 [RCV000677958] Chr1:191919194..194615758 [GRCh38]
Chr1:191888324..194584888 [GRCh37]
Chr1:1q31.2-31.3		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1q25.3-41(chr1:185644663-221698833)x3 copy number gain not provided [RCV000749265] Chr1:185644663..221698833 [GRCh37]
Chr1:1q25.3-41		 pathogenic
GRCh37/hg19 1q25.3-44(chr1:182388773-249111240)x3 copy number gain not provided [RCV000845852] Chr1:182388773..249111240 [GRCh37]
Chr1:1q25.3-44		 pathogenic
GRCh37/hg19 1q25.2-32.1(chr1:177551193-199599056)x1 copy number loss not provided [RCV001005157] Chr1:177551193..199599056 [GRCh37]
Chr1:1q25.2-32.1		 pathogenic
NC_000001.10:g.(?_130980840)_(248900000_?)dup duplication Gastrointestinal stromal tumor [RCV001300221]|Parathyroid carcinoma [RCV001341077] Chr1:130980840..248900000 [GRCh37]
Chr1:1q12-44		 uncertain significance
GRCh37/hg19 1q25.2-32.1(chr1:179073386-200192265) copy number loss not specified [RCV002053769] Chr1:179073386..200192265 [GRCh37]
Chr1:1q25.2-32.1		 pathogenic
GRCh37/hg19 1q24.3-31.3(chr1:171990029-195086758) copy number loss not specified [RCV002053736] Chr1:171990029..195086758 [GRCh37]
Chr1:1q24.3-31.3		 pathogenic
GRCh37/hg19 1q25.2-32.1(chr1:179413479-201764737) copy number loss not specified [RCV002053780] Chr1:179413479..201764737 [GRCh37]
Chr1:1q25.2-32.1		 pathogenic
NM_002927.5(RGS13):c.451A>G (p.Lys151Glu) single nucleotide variant not specified [RCV004305315] Chr1:192659494 [GRCh38]
Chr1:192628624 [GRCh37]
Chr1:1q31.2		 uncertain significance
GRCh37/hg19 1q31.1-32.1(chr1:189633885-199854163)x1 copy number loss not provided [RCV002472500] Chr1:189633885..199854163 [GRCh37]
Chr1:1q31.1-32.1		 likely pathogenic
GRCh37/hg19 1q25.3-32.3(chr1:181453460-213107248)x3 copy number gain not provided [RCV002475637] Chr1:181453460..213107248 [GRCh37]
Chr1:1q25.3-32.3		 pathogenic
NM_002927.5(RGS13):c.389T>C (p.Met130Thr) single nucleotide variant not specified [RCV004242979] Chr1:192659432 [GRCh38]
Chr1:192628562 [GRCh37]
Chr1:1q31.2		 uncertain significance
NM_002927.5(RGS13):c.58C>T (p.Pro20Ser) single nucleotide variant not specified [RCV004212746] Chr1:192644392 [GRCh38]
Chr1:192613522 [GRCh37]
Chr1:1q31.2		 uncertain significance
NM_002927.5(RGS13):c.10C>T (p.Arg4Trp) single nucleotide variant not specified [RCV004179683] Chr1:192644344 [GRCh38]
Chr1:192613474 [GRCh37]
Chr1:1q31.2		 uncertain significance
NM_002927.5(RGS13):c.8G>A (p.Arg3Lys) single nucleotide variant not specified [RCV004255251] Chr1:192644342 [GRCh38]
Chr1:192613472 [GRCh37]
Chr1:1q31.2		 uncertain significance
NM_002927.5(RGS13):c.311C>T (p.Ser104Leu) single nucleotide variant not specified [RCV004253568] Chr1:192659354 [GRCh38]
Chr1:192628484 [GRCh37]
Chr1:1q31.2		 uncertain significance
NM_002927.5(RGS13):c.192G>T (p.Trp64Cys) single nucleotide variant not specified [RCV004449123] Chr1:192658265 [GRCh38]
Chr1:192627395 [GRCh37]
Chr1:1q31.2		 uncertain significance
NM_002927.5(RGS13):c.302T>C (p.Ile101Thr) single nucleotide variant not specified [RCV004449124] Chr1:192659345 [GRCh38]
Chr1:192628475 [GRCh37]
Chr1:1q31.2		 uncertain significance
NM_002927.5(RGS13):c.47C>A (p.Ser16Tyr) single nucleotide variant not specified [RCV004449125] Chr1:192644381 [GRCh38]
Chr1:192613511 [GRCh37]
Chr1:1q31.2		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:481
Count of miRNA genes:214
Interacting mature miRNAs:222
Transcripts:ENST00000391995, ENST00000462955, ENST00000482095, ENST00000543215
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-76069  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371192,629,113 - 192,629,293UniSTSGRCh37
Build 361190,895,736 - 190,895,916RGDNCBI36
Celera1165,738,836 - 165,739,016RGD
Cytogenetic Map1q31.2UniSTS
HuRef1163,865,052 - 163,865,232UniSTS
TNG Radiation Hybrid Map193750.0UniSTS
GeneMap99-GB4 RH Map1646.97UniSTS
RH98634  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371192,603,386 - 192,603,531UniSTSGRCh37
Build 361190,870,009 - 190,870,154RGDNCBI36
Celera1165,713,175 - 165,713,320RGD
Cytogenetic Map1q31.2UniSTS
HuRef1163,839,387 - 163,839,532UniSTS
GeneMap99-GB4 RH Map1650.15UniSTS
RGS13_2430  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371192,628,699 - 192,629,557UniSTSGRCh37
Build 361190,895,322 - 190,896,180RGDNCBI36
Celera1165,738,422 - 165,739,280RGD
HuRef1163,864,638 - 163,865,496UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 4 2 200 1 1 5
Low 1098 107 78 58 556 15 1093 533 230 45 288 578 46 515 526 1
Below cutoff 1192 2359 1152 356 751 237 2848 1402 2099 189 912 602 118 687 2077 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000391995   ⟹   ENSP00000375853
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1192,636,147 - 192,660,311 (+)Ensembl
RefSeq Acc Id: ENST00000462955
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1192,636,145 - 192,660,260 (+)Ensembl
RefSeq Acc Id: ENST00000482095
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1192,644,531 - 192,659,862 (+)Ensembl
RefSeq Acc Id: ENST00000543215   ⟹   ENSP00000442837
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1192,636,138 - 192,660,306 (+)Ensembl
RefSeq Acc Id: NM_002927   ⟹   NP_002918
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381192,636,147 - 192,660,311 (+)NCBI
GRCh371192,605,268 - 192,629,441 (+)ENTREZGENE
Build 361190,871,905 - 190,896,013 (+)NCBI Archive
Celera1165,715,071 - 165,739,113 (+)RGD
HuRef1163,841,268 - 163,865,380 (+)ENTREZGENE
CHM1_11194,027,097 - 194,051,266 (+)NCBI
T2T-CHM13v2.01191,983,284 - 192,007,378 (+)NCBI
Sequence:
RefSeq Acc Id: NM_144766   ⟹   NP_658912
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381192,636,147 - 192,660,311 (+)NCBI
GRCh371192,605,268 - 192,629,441 (+)ENTREZGENE
Build 361190,871,905 - 190,896,013 (+)NCBI Archive
Celera1165,715,071 - 165,739,113 (+)RGD
HuRef1163,841,268 - 163,865,380 (+)ENTREZGENE
CHM1_11194,027,097 - 194,051,266 (+)NCBI
T2T-CHM13v2.01191,983,284 - 192,007,378 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_002918   ⟸   NM_002927
- UniProtKB: Q8TD63 (UniProtKB/Swiss-Prot),   Q6PGR2 (UniProtKB/Swiss-Prot),   Q9BX45 (UniProtKB/Swiss-Prot),   O14921 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_658912   ⟸   NM_144766
- UniProtKB: Q8TD63 (UniProtKB/Swiss-Prot),   Q6PGR2 (UniProtKB/Swiss-Prot),   Q9BX45 (UniProtKB/Swiss-Prot),   O14921 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000442837   ⟸   ENST00000543215
RefSeq Acc Id: ENSP00000375853   ⟸   ENST00000391995
Protein Domains
RGS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O14921-F1-model_v2 AlphaFold O14921 1-159 view protein structure

Promoters
RGD ID:6786420
Promoter ID:HG_KWN:6621
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:OTTHUMT00000086400,   OTTHUMT00000086401
Position:
Human AssemblyChrPosition (strand)Source
Build 361190,871,641 - 190,872,141 (+)MPROMDB
RGD ID:6858426
Promoter ID:EPDNEW_H2378
Type:initiation region
Name:RGS13_2
Description:regulator of G protein signaling 13
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H2377  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381192,636,158 - 192,636,218EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:9995 AgrOrtholog
COSMIC RGS13 COSMIC
Ensembl Genes ENSG00000127074 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000391995 ENTREZGENE
  ENST00000391995.7 UniProtKB/Swiss-Prot
  ENST00000543215 ENTREZGENE
  ENST00000543215.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.167.10 UniProtKB/Swiss-Prot
  1.10.196.10 UniProtKB/Swiss-Prot
GTEx ENSG00000127074 GTEx
HGNC ID HGNC:9995 ENTREZGENE
Human Proteome Map RGS13 Human Proteome Map
InterPro RGS UniProtKB/Swiss-Prot
  RGS_sf UniProtKB/Swiss-Prot
  RGS_subdom1/3 UniProtKB/Swiss-Prot
  RGS_subdomain_2 UniProtKB/Swiss-Prot
KEGG Report hsa:6003 UniProtKB/Swiss-Prot
NCBI Gene 6003 ENTREZGENE
OMIM 607190 OMIM
PANTHER PTHR10845:SF32 UniProtKB/Swiss-Prot
  REGULATOR OF G PROTEIN SIGNALING UniProtKB/Swiss-Prot
Pfam RGS UniProtKB/Swiss-Prot
PharmGKB PA34365 PharmGKB
PRINTS RGSPROTEIN UniProtKB/Swiss-Prot
PROSITE RGS UniProtKB/Swiss-Prot
SMART RGS UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48097 UniProtKB/Swiss-Prot
UniProt O14921 ENTREZGENE
  Q6PGR2 ENTREZGENE
  Q8TD63 ENTREZGENE
  Q9BX45 ENTREZGENE
  RGS13_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary Q6PGR2 UniProtKB/Swiss-Prot
  Q8TD63 UniProtKB/Swiss-Prot
  Q9BX45 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-04-18 RGS13  regulator of G protein signaling 13  RGS13  regulator of G-protein signaling 13  Symbol and/or name change 5135510 APPROVED