IGFL2 (IGF like family member 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: IGFL2 (IGF like family member 2) Homo sapiens
Analyze
Symbol: IGFL2
Name: IGF like family member 2
RGD ID: 1604232
HGNC Page HGNC:32929
Description: Enables signaling receptor binding activity. Located in extracellular space.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: IGF-like family member 2; insulin growth factor-like family member 2; LOC124908086; uncharacterized LOC124908086; UNQ645; VPRI645
RGD Orthologs
Bonobo
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381946,078,513 - 46,215,362 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1946,143,106 - 46,161,298 (+)EnsemblGRCh38hg38GRCh38
GRCh371946,651,039 - 46,664,546 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361951,342,879 - 51,356,386 (+)NCBINCBI36Build 36hg18NCBI36
Celera1943,456,014 - 43,469,536 (+)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1943,078,534 - 43,092,040 (+)NCBIHuRef
CHM1_11946,653,241 - 46,666,747 (+)NCBICHM1_1
T2T-CHM13v2.01948,905,965 - 49,042,808 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:12975309   PMID:14702039   PMID:16890402   PMID:21454693   PMID:21873635   PMID:32296183  


Genomics

Comparative Map Data
IGFL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381946,078,513 - 46,215,362 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1946,143,106 - 46,161,298 (+)EnsemblGRCh38hg38GRCh38
GRCh371946,651,039 - 46,664,546 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361951,342,879 - 51,356,386 (+)NCBINCBI36Build 36hg18NCBI36
Celera1943,456,014 - 43,469,536 (+)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1943,078,534 - 43,092,040 (+)NCBIHuRef
CHM1_11946,653,241 - 46,666,747 (+)NCBICHM1_1
T2T-CHM13v2.01948,905,965 - 49,042,808 (+)NCBIT2T-CHM13v2.0
IGFL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22052,338,877 - 52,340,795 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11954,210,020 - 54,211,938 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01943,095,495 - 43,184,377 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11951,706,887 - 51,720,296 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1951,719,406 - 51,720,097 (+)Ensemblpanpan1.1panPan2

Variants

.
Variants in IGFL2
13 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19q13.32(chr19:45595873-46600026)x1 copy number loss See cases [RCV000050710] Chr19:45595873..46600026 [GRCh38]
Chr19:46099131..47103283 [GRCh37]
Chr19:50790971..51795123 [NCBI36]
Chr19:19q13.32		 pathogenic
GRCh38/hg38 19q13.32-13.33(chr19:44971420-48257402)x3 copy number gain See cases [RCV000136578] Chr19:44971420..48257402 [GRCh38]
Chr19:45474677..48760659 [GRCh37]
Chr19:50166517..53452471 [NCBI36]
Chr19:19q13.32-13.33		 pathogenic
GRCh38/hg38 19q13.32(chr19:45387389-46831000)x1 copy number loss See cases [RCV000137832] Chr19:45387389..46831000 [GRCh38]
Chr19:45890647..47334257 [GRCh37]
Chr19:50582487..52026097 [NCBI36]
Chr19:19q13.32		 likely pathogenic
GRCh37/hg19 19q13.2-13.32(chr19:43013365-47241534)x1 copy number loss See cases [RCV000240182] Chr19:43013365..47241534 [GRCh37]
Chr19:19q13.2-13.32		 pathogenic
GRCh37/hg19 19q13.32(chr19:46638760-46743231)x3 copy number gain not provided [RCV000762780] Chr19:46638760..46743231 [GRCh37]
Chr19:19q13.32		 likely benign
GRCh37/hg19 19q13.32-13.33(chr19:46404248-48488721)x1 copy number loss See cases [RCV000511362] Chr19:46404248..48488721 [GRCh37]
Chr19:19q13.32-13.33		 likely pathogenic
NM_001135113.2(IGFL2):c.80C>T (p.Ala27Val) single nucleotide variant not specified [RCV004283788] Chr19:46160620 [GRCh38]
Chr19:46663877 [GRCh37]
Chr19:19q13.32		 likely benign
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
NM_207393.2(IGFL3):c.128G>A (p.Cys43Tyr) single nucleotide variant not specified [RCV004309468] Chr19:46124108 [GRCh38]
Chr19:46627365 [GRCh37]
Chr19:19q13.32		 uncertain significance
NM_207393.2(IGFL3):c.32T>C (p.Val11Ala) single nucleotide variant not specified [RCV004305817] Chr19:46124315 [GRCh38]
Chr19:46627572 [GRCh37]
Chr19:19q13.32		 uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19q13.31-13.42(chr19:44738088-53621561)x3 copy number gain not provided [RCV001007050] Chr19:44738088..53621561 [GRCh37]
Chr19:19q13.31-13.42		 pathogenic
GRCh37/hg19 19q11-13.33(chr19:28271106-49213832)x3 copy number gain not provided [RCV000845733] Chr19:28271106..49213832 [GRCh37]
Chr19:19q11-13.33		 pathogenic
GRCh37/hg19 19q13.32-13.33(chr19:45531056-48174177)x3 copy number gain not provided [RCV001007051] Chr19:45531056..48174177 [GRCh37]
Chr19:19q13.32-13.33		 uncertain significance
GRCh37/hg19 19q13.32(chr19:46645877-46868805)x1 copy number loss not provided [RCV001259942] Chr19:46645877..46868805 [GRCh37]
Chr19:19q13.32		 uncertain significance
NM_207393.2(IGFL3):c.316T>G (p.Cys106Gly) single nucleotide variant not specified [RCV004162902] Chr19:46123920 [GRCh38]
Chr19:46627177 [GRCh37]
Chr19:19q13.32		 uncertain significance
NM_001135113.2(IGFL2):c.61A>G (p.Arg21Gly) single nucleotide variant not specified [RCV004092087] Chr19:46160456 [GRCh38]
Chr19:46663713 [GRCh37]
Chr19:19q13.32		 uncertain significance
NM_207393.2(IGFL3):c.257C>T (p.Ser86Phe) single nucleotide variant not specified [RCV004145519] Chr19:46123979 [GRCh38]
Chr19:46627236 [GRCh37]
Chr19:19q13.32		 uncertain significance
NM_207393.2(IGFL3):c.316T>C (p.Cys106Arg) single nucleotide variant not specified [RCV004108777] Chr19:46123920 [GRCh38]
Chr19:46627177 [GRCh37]
Chr19:19q13.32		 uncertain significance
NM_001135113.2(IGFL2):c.223T>C (p.Cys75Arg) single nucleotide variant not specified [RCV004075531] Chr19:46160763 [GRCh38]
Chr19:46664020 [GRCh37]
Chr19:19q13.32		 uncertain significance
NM_207393.2(IGFL3):c.217T>G (p.Cys73Gly) single nucleotide variant not specified [RCV004231877] Chr19:46124019 [GRCh38]
Chr19:46627276 [GRCh37]
Chr19:19q13.32		 uncertain significance
NM_207393.2(IGFL3):c.116C>T (p.Pro39Leu) single nucleotide variant not specified [RCV004257445] Chr19:46124120 [GRCh38]
Chr19:46627377 [GRCh37]
Chr19:19q13.32		 uncertain significance
NM_001135113.2(IGFL2):c.55T>A (p.Cys19Ser) single nucleotide variant not specified [RCV004344178] Chr19:46160450 [GRCh38]
Chr19:46663707 [GRCh37]
Chr19:19q13.32		 uncertain significance
NM_001135113.2(IGFL2):c.266A>G (p.Asp89Gly) single nucleotide variant not specified [RCV004402525] Chr19:46160806 [GRCh38]
Chr19:46664063 [GRCh37]
Chr19:19q13.32		 uncertain significance
NM_001135113.2(IGFL2):c.350G>A (p.Arg117His) single nucleotide variant not specified [RCV004402526] Chr19:46161078 [GRCh38]
Chr19:46664335 [GRCh37]
Chr19:19q13.32		 uncertain significance
NM_207393.2(IGFL3):c.215C>A (p.Thr72Asn) single nucleotide variant not specified [RCV004402527] Chr19:46124021 [GRCh38]
Chr19:46627278 [GRCh37]
Chr19:19q13.32		 likely benign
NM_207393.2(IGFL3):c.268C>A (p.Gln90Lys) single nucleotide variant not specified [RCV004402528] Chr19:46123968 [GRCh38]
Chr19:46627225 [GRCh37]
Chr19:19q13.32		 uncertain significance
NM_207393.2(IGFL3):c.344G>A (p.Cys115Tyr) single nucleotide variant not specified [RCV004402529] Chr19:46123892 [GRCh38]
Chr19:46627149 [GRCh37]
Chr19:19q13.32		 uncertain significance
NM_207393.2(IGFL3):c.82G>A (p.Ala28Thr) single nucleotide variant not specified [RCV004402530] Chr19:46124154 [GRCh38]
Chr19:46627411 [GRCh37]
Chr19:19q13.32		 uncertain significance
NM_001135113.2(IGFL2):c.166G>A (p.Ala56Thr) single nucleotide variant not specified [RCV004344454] Chr19:46160706 [GRCh38]
Chr19:46663963 [GRCh37]
Chr19:19q13.32		 uncertain significance
NM_207393.2(IGFL3):c.11G>A (p.Arg4Gln) single nucleotide variant not specified [RCV004288273] Chr19:46124639 [GRCh38]
Chr19:46627896 [GRCh37]
Chr19:19q13.32		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:414
Count of miRNA genes:168
Interacting mature miRNAs:172
Transcripts:ENST00000377693, ENST00000434646, ENST00000593592, ENST00000600243, ENST00000601052
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH92919  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371946,664,095 - 46,664,435UniSTSGRCh37
Build 361951,355,935 - 51,356,275RGDNCBI36
Celera1943,469,070 - 43,469,410RGD
Cytogenetic Map19q13.32UniSTS
HuRef1943,091,574 - 43,091,914UniSTS
GeneMap99-GB4 RH Map19252.34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 35 1 12 7 1 3 1275 2 4 269 30 6 34 688 1
Low 250 166 234 56 70 25 471 28 846 33 374 209 36 329 378 2
Below cutoff 1640 1878 712 260 854 152 1779 1319 2521 146 543 771 113 581 1255 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001002915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001135113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011526501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024451381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047438227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047438228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054319899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054319900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054319901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054319902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054319903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054319904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054319905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001753604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001753605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007066604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007066605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007066606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007066607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007066608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007066609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007066610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007066611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007066612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007066613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007066614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007066615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007066616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007066617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007089175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_935743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_935744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC006262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC007785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK093330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK125754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW009166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY358692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY672112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC130490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC130492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF511271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OA987066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000377693   ⟹   ENSP00000366922
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1946,148,238 - 46,161,289 (+)Ensembl
RefSeq Acc Id: ENST00000434646   ⟹   ENSP00000395219
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1946,147,782 - 46,161,289 (+)Ensembl
RefSeq Acc Id: ENST00000593592
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1946,159,046 - 46,161,298 (+)Ensembl
RefSeq Acc Id: ENST00000600243
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1946,143,106 - 46,161,288 (+)Ensembl
RefSeq Acc Id: ENST00000601052   ⟹   ENSP00000471085
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1946,160,643 - 46,161,288 (+)Ensembl
RefSeq Acc Id: NM_001002915   ⟹   NP_001002915
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,147,782 - 46,161,289 (+)NCBI
GRCh371946,651,039 - 46,664,561 (+)RGD
Build 361951,342,879 - 51,356,386 (+)NCBI Archive
Celera1943,456,014 - 43,469,536 (+)RGD
HuRef1943,078,534 - 43,092,040 (+)RGD
CHM1_11946,653,241 - 46,666,747 (+)NCBI
T2T-CHM13v2.01948,975,170 - 48,988,661 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001135113   ⟹   NP_001128585
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,148,238 - 46,161,289 (+)NCBI
GRCh371946,651,039 - 46,664,561 (+)RGD
Celera1943,456,014 - 43,469,536 (+)RGD
HuRef1943,078,534 - 43,092,040 (+)RGD
CHM1_11946,653,702 - 46,666,747 (+)NCBI
T2T-CHM13v2.01948,975,626 - 48,988,661 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024451381   ⟹   XP_024307149
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,079,132 - 46,161,289 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047438227   ⟹   XP_047294183
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,148,238 - 46,161,289 (+)NCBI
RefSeq Acc Id: XM_047438228   ⟹   XP_047294184
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,079,132 - 46,161,289 (+)NCBI
RefSeq Acc Id: XM_054319899   ⟹   XP_054175874
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 48,988,661 (+)NCBI
RefSeq Acc Id: XM_054319900   ⟹   XP_054175875
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 48,988,661 (+)NCBI
RefSeq Acc Id: XM_054319901   ⟹   XP_054175876
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 48,988,661 (+)NCBI
RefSeq Acc Id: XM_054319902   ⟹   XP_054175877
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,975,701 - 48,988,661 (+)NCBI
RefSeq Acc Id: XM_054319903   ⟹   XP_054175878
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,975,626 - 48,988,671 (+)NCBI
RefSeq Acc Id: XM_054319904   ⟹   XP_054175879
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 48,988,661 (+)NCBI
RefSeq Acc Id: XM_054319905   ⟹   XP_054175880
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 48,988,661 (+)NCBI
RefSeq Acc Id: XR_001753604
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,078,513 - 46,160,707 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001753605
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,078,513 - 46,160,707 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002958257
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,079,132 - 46,214,838 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002958269
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,079,132 - 46,214,838 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002958271
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,079,132 - 46,197,647 (+)NCBI
Sequence:
RefSeq Acc Id: XR_007066604
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,078,513 - 46,160,707 (+)NCBI
RefSeq Acc Id: XR_007066605
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,078,513 - 46,196,824 (+)NCBI
RefSeq Acc Id: XR_007066606
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,078,513 - 46,160,628 (+)NCBI
RefSeq Acc Id: XR_007066607
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,079,132 - 46,214,838 (+)NCBI
RefSeq Acc Id: XR_007066608
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,079,132 - 46,215,362 (+)NCBI
RefSeq Acc Id: XR_007066609
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,079,132 - 46,214,838 (+)NCBI
RefSeq Acc Id: XR_007066610
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,079,132 - 46,214,838 (+)NCBI
RefSeq Acc Id: XR_007066611
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,079,132 - 46,214,838 (+)NCBI
RefSeq Acc Id: XR_007066612
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,079,132 - 46,214,838 (+)NCBI
RefSeq Acc Id: XR_007066613
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,079,132 - 46,214,838 (+)NCBI
RefSeq Acc Id: XR_007066614
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,079,132 - 46,214,838 (+)NCBI
RefSeq Acc Id: XR_007066615
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,079,132 - 46,214,838 (+)NCBI
RefSeq Acc Id: XR_007066616
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,079,132 - 46,214,838 (+)NCBI
RefSeq Acc Id: XR_007066617
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,079,132 - 46,214,838 (+)NCBI
RefSeq Acc Id: XR_007089175
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 49,025,074 (+)NCBI
RefSeq Acc Id: XR_008485088
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,905,965 - 48,988,079 (+)NCBI
RefSeq Acc Id: XR_008485089
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,905,965 - 48,988,079 (+)NCBI
RefSeq Acc Id: XR_008485090
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,905,965 - 48,988,661 (+)NCBI
RefSeq Acc Id: XR_008485091
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,905,965 - 48,988,000 (+)NCBI
RefSeq Acc Id: XR_008485092
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 49,042,282 (+)NCBI
RefSeq Acc Id: XR_008485093
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 49,042,282 (+)NCBI
RefSeq Acc Id: XR_008485094
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 49,042,808 (+)NCBI
RefSeq Acc Id: XR_008485095
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 49,042,282 (+)NCBI
RefSeq Acc Id: XR_008485096
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 49,042,282 (+)NCBI
RefSeq Acc Id: XR_008485097
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 49,042,282 (+)NCBI
RefSeq Acc Id: XR_008485098
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 49,042,282 (+)NCBI
RefSeq Acc Id: XR_008485099
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 49,042,282 (+)NCBI
RefSeq Acc Id: XR_008485100
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 49,042,282 (+)NCBI
RefSeq Acc Id: XR_008485101
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 49,042,282 (+)NCBI
RefSeq Acc Id: XR_008485102
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 49,042,282 (+)NCBI
RefSeq Acc Id: XR_008485103
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 49,042,282 (+)NCBI
RefSeq Acc Id: XR_008485104
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01948,906,490 - 49,042,282 (+)NCBI
RefSeq Acc Id: XR_935743
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,078,513 - 46,161,289 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001002915   ⟸   NM_001002915
- Peptide Label: isoform a
- UniProtKB: Q6UWQ7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001128585   ⟸   NM_001135113
- Peptide Label: isoform b precursor
- UniProtKB: E9PAV1 (UniProtKB/Swiss-Prot),   Q6B9Z3 (UniProtKB/Swiss-Prot),   Q6UWQ7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_024307149   ⟸   XM_024451381
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSP00000366922   ⟸   ENST00000377693
RefSeq Acc Id: ENSP00000471085   ⟸   ENST00000601052
RefSeq Acc Id: ENSP00000395219   ⟸   ENST00000434646
RefSeq Acc Id: XP_047294184   ⟸   XM_047438228
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047294183   ⟸   XM_047438227
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054175874   ⟸   XM_054319899
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054175879   ⟸   XM_054319904
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054175875   ⟸   XM_054319900
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054175880   ⟸   XM_054319905
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054175876   ⟸   XM_054319901
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054175878   ⟸   XM_054319903
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054175877   ⟸   XM_054319902
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6UWQ7-F1-model_v2 AlphaFold Q6UWQ7 1-119 view protein structure

Promoters
RGD ID:12914155
Promoter ID:EPDNEW_H25989
Type:initiation region
Name:IGFL2_1
Description:IGF like family member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381946,148,239 - 46,148,299EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:32929 AgrOrtholog
COSMIC IGFL2 COSMIC
Ensembl Genes ENSG00000204866 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000377693 ENTREZGENE
  ENST00000377693.5 UniProtKB/Swiss-Prot
  ENST00000434646 ENTREZGENE
  ENST00000434646.6 UniProtKB/Swiss-Prot
  ENST00000601052.1 UniProtKB/TrEMBL
GTEx ENSG00000204866 GTEx
HGNC ID HGNC:32929 ENTREZGENE
Human Proteome Map IGFL2 Human Proteome Map
InterPro IGFL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:147920 UniProtKB/Swiss-Prot
NCBI Gene 147920 ENTREZGENE
OMIM 610545 OMIM
PANTHER INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR34827 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IGFL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA147357935 PharmGKB
UniProt E9PAV1 ENTREZGENE
  IGFL2_HUMAN UniProtKB/Swiss-Prot
  M0R089_HUMAN UniProtKB/TrEMBL
  Q6B9Z3 ENTREZGENE
  Q6UWQ7 ENTREZGENE
UniProt Secondary E9PAV1 UniProtKB/Swiss-Prot
  Q6B9Z3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-03-23 IGFL2  IGF like family member 2  LOC124908086  uncharacterized LOC124908086  Data merged from RGD:151674130 737654 PROVISIONAL
2015-11-24 IGFL2  IGF like family member 2  IGFL2  IGF-like family member 2  Symbol and/or name change 5135510 APPROVED