Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Megf11 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MEGF11 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Megf11 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MEGF11 mRNA | CTD | PMID:33387578 | 6-propyl-2-thiouracil | decreases expression | ISO | Megf11 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of MEGF11 mRNA | CTD | PMID:24780913 | acrylamide | increases expression | ISO | Megf11 (Rattus norvegicus) | 6480464 | Acrylamide results in increased expression of MEGF11 mRNA | CTD | PMID:28959563 | Aflatoxin B2 alpha | increases methylation | EXP | | 6480464 | aflatoxin B2 results in increased methylation of MEGF11 intron | CTD | PMID:30157460 | all-trans-retinoic acid | multiple interactions | ISO | Megf11 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MEGF11 mRNA | CTD | PMID:36189433 | alpha-Zearalanol | multiple interactions | ISO | Megf11 (Rattus norvegicus) | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of MEGF11 mRNA | CTD | PMID:35163327 | aristolochic acid A | increases expression | EXP | | 6480464 | aristolochic acid I results in increased expression of MEGF11 mRNA | CTD | PMID:33212167 | arsane | affects methylation | EXP | | 6480464 | Arsenic affects the methylation of MEGF11 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | EXP | | 6480464 | Arsenic affects the methylation of MEGF11 gene | CTD | PMID:25304211 | atrazine | affects methylation | ISO | Megf11 (Rattus norvegicus) | 6480464 | Atrazine affects the methylation of MEGF11 gene | CTD | PMID:28931070 and PMID:35440735 | benzo[a]pyrene | decreases expression | ISO | Megf11 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of MEGF11 mRNA | CTD | PMID:27195522 | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of MEGF11 promoter | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of MEGF11 5' UTR and Benzo(a)pyrene affects the methylation of MEGF11 intron | CTD | PMID:27901495 and PMID:30157460 | benzo[e]pyrene | increases methylation | EXP | | 6480464 | benzo(e)pyrene results in increased methylation of MEGF11 intron | CTD | PMID:30157460 | bisphenol A | decreases expression | ISO | Megf11 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of MEGF11 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Megf11 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of MEGF11 mRNA | CTD | PMID:32156529 | bisphenol A | affects methylation | EXP | | 6480464 | bisphenol A affects the methylation of MEGF11 gene | CTD | PMID:31601247 | cadmium atom | multiple interactions | ISO | Megf11 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MEGF11 mRNA | CTD | PMID:37325564 | cadmium dichloride | multiple interactions | ISO | Megf11 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MEGF11 mRNA | CTD | PMID:37325564 | chlorpyrifos | increases expression | ISO | Megf11 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of MEGF11 mRNA | CTD | PMID:37019170 | clothianidin | multiple interactions | ISO | Megf11 (Rattus norvegicus) | 6480464 | [enilconazole co-treated with clothianidin] results in decreased expression of MEGF11 mRNA and [thiacloprid co-treated with clothianidin] results in decreased expression of MEGF11 mRNA | CTD | PMID:33426623 | clothianidin | decreases expression | ISO | Megf11 (Rattus norvegicus) | 6480464 | clothianidin results in decreased expression of MEGF11 mRNA | CTD | PMID:33426623 | enilconazole | multiple interactions | ISO | Megf11 (Rattus norvegicus) | 6480464 | [enilconazole co-treated with clothianidin] results in decreased expression of MEGF11 mRNA and [thiacloprid co-treated with enilconazole] results in decreased expression of MEGF11 mRNA | CTD | PMID:33426623 | enilconazole | decreases expression | ISO | Megf11 (Rattus norvegicus) | 6480464 | enilconazole results in decreased expression of MEGF11 mRNA | CTD | PMID:33426623 | ethylparaben | decreases expression | EXP | | 6480464 | ethyl-p-hydroxybenzoate results in decreased expression of MEGF11 mRNA | CTD | PMID:37690743 | fipronil | decreases expression | ISO | Megf11 (Rattus norvegicus) | 6480464 | fipronil results in decreased expression of MEGF11 mRNA | CTD | PMID:23962444 | folic acid | decreases expression | ISO | Megf11 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of MEGF11 mRNA | CTD | PMID:25629700 | Genipin | multiple interactions | ISO | Megf11 (Mus musculus) | 6480464 | genipin inhibits the reaction [Lipopolysaccharides results in increased expression of MEGF11 mRNA] | CTD | PMID:22687549 | GW 4064 | decreases expression | ISO | Megf11 (Mus musculus) | 6480464 | GW 4064 results in decreased expression of MEGF11 mRNA | CTD | PMID:26655953 | lipopolysaccharide | multiple interactions | ISO | Megf11 (Mus musculus) | 6480464 | genipin inhibits the reaction [Lipopolysaccharides results in increased expression of MEGF11 mRNA] | CTD | PMID:22687549 | lipopolysaccharide | increases expression | ISO | Megf11 (Mus musculus) | 6480464 | Lipopolysaccharides results in increased expression of MEGF11 mRNA | CTD | PMID:22687549 | methapyrilene | increases methylation | EXP | | 6480464 | Methapyrilene results in increased methylation of MEGF11 intron | CTD | PMID:30157460 | methoxychlor | affects methylation | ISO | Megf11 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of MEGF11 gene | CTD | PMID:35440735 | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | Megf11 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MEGF11 mRNA | CTD | PMID:36189433 | ozone | multiple interactions | ISO | Megf11 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of MEGF11 mRNA | CTD | PMID:27106289 | pentanal | increases expression | EXP | | 6480464 | pentanal results in increased expression of MEGF11 mRNA | CTD | PMID:26079696 | perfluorohexanesulfonic acid | decreases expression | ISO | Megf11 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of MEGF11 mRNA | CTD | PMID:37995155 | perfluorooctanoic acid | multiple interactions | ISO | Megf11 (Rattus norvegicus) | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of MEGF11 mRNA | CTD | PMID:35163327 | propanal | increases expression | EXP | | 6480464 | propionaldehyde results in increased expression of MEGF11 mRNA | CTD | PMID:26079696 | resveratrol | multiple interactions | EXP | | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of MEGF11 mRNA | CTD | PMID:23557933 | tetrachloromethane | decreases expression | ISO | Megf11 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of MEGF11 mRNA | CTD | PMID:31150632 | thiacloprid | decreases expression | ISO | Megf11 (Rattus norvegicus) | 6480464 | thiacloprid results in decreased expression of MEGF11 mRNA | CTD | PMID:33426623 | thiacloprid | multiple interactions | ISO | Megf11 (Rattus norvegicus) | 6480464 | [thiacloprid co-treated with clothianidin] results in decreased expression of MEGF11 mRNA and [thiacloprid co-treated with enilconazole] results in decreased expression of MEGF11 mRNA | CTD | PMID:33426623 | trichloroethene | decreases expression | ISO | Megf11 (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased expression of MEGF11 mRNA | CTD | PMID:33387578 | valproic acid | affects expression | ISO | Megf11 (Mus musculus) | 6480464 | Valproic Acid affects the expression of MEGF11 mRNA | CTD | PMID:17963808 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of MEGF11 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of MEGF11 mRNA | CTD | PMID:23179753 more ... | vinclozolin | increases methylation | ISO | Megf11 (Rattus norvegicus) | 6480464 | vinclozolin results in increased methylation of MEGF11 gene | CTD | PMID:31079544 | zoledronic acid | increases expression | EXP | | 6480464 | zoledronic acid results in increased expression of MEGF11 mRNA | CTD | PMID:24714768 | |