SPRYD4 (SPRY domain containing 4) - Rat Genome Database

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Gene: SPRYD4 (SPRY domain containing 4) Homo sapiens
Analyze
Symbol: SPRYD4
Name: SPRY domain containing 4
RGD ID: 1603522
HGNC Page HGNC:27468
Description: Located in nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DKFZp686N0877; SPRY domain-containing protein 4
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381256,468,578 - 56,479,708 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1256,468,578 - 56,479,708 (+)EnsemblGRCh38hg38GRCh38
GRCh371256,862,362 - 56,873,492 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361255,148,629 - 55,150,067 (+)NCBINCBI36Build 36hg18NCBI36
Celera1256,515,670 - 56,518,138 (+)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1253,901,342 - 53,903,812 (+)NCBIHuRef
CHM1_11256,829,960 - 56,832,430 (+)NCBICHM1_1
T2T-CHM13v2.01256,436,289 - 56,447,410 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:16344560   PMID:17852359   PMID:20877624   PMID:22286219   PMID:22658674   PMID:22916037   PMID:24144296   PMID:24292625   PMID:26496610   PMID:27499296  
PMID:28514442   PMID:29568061   PMID:30238408   PMID:31056398   PMID:31586073   PMID:32296183   PMID:32628020   PMID:32877691   PMID:33950983   PMID:33961781   PMID:34079125   PMID:36215168  
PMID:37142983  


Genomics

Comparative Map Data
SPRYD4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381256,468,578 - 56,479,708 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1256,468,578 - 56,479,708 (+)EnsemblGRCh38hg38GRCh38
GRCh371256,862,362 - 56,873,492 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361255,148,629 - 55,150,067 (+)NCBINCBI36Build 36hg18NCBI36
Celera1256,515,670 - 56,518,138 (+)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1253,901,342 - 53,903,812 (+)NCBIHuRef
CHM1_11256,829,960 - 56,832,430 (+)NCBICHM1_1
T2T-CHM13v2.01256,436,289 - 56,447,410 (+)NCBIT2T-CHM13v2.0
Spryd4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,045,777 - 128,047,663 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10128,045,777 - 128,047,676 (-)EnsemblGRCm39 Ensembl
GRCm3810128,209,908 - 128,211,794 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,209,908 - 128,211,807 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710127,646,964 - 127,648,850 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610127,612,857 - 127,614,743 (-)NCBIMGSCv36mm8
Celera10130,604,745 - 130,606,633 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1076.44NCBI
Spryd4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,217,984 - 1,222,231 (-)NCBIGRCr8
mRatBN7.27633,400 - 637,564 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7633,394 - 637,557 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,391,989 - 3,393,809 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,268,005 - 5,269,825 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.075,569,826 - 5,571,646 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.072,621,960 - 2,625,982 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,621,961 - 2,623,781 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,600,836 - 2,604,858 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,495,475 - 1,497,060 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.171,495,959 - 1,497,054 (-)NCBI
Celera7512,078 - 513,899 (-)NCBICelera
Cytogenetic Map7q11NCBI
Spryd4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554584,051,978 - 4,053,734 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554584,051,978 - 4,053,734 (+)NCBIChiLan1.0ChiLan1.0
SPRYD4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21037,860,329 - 37,862,800 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11237,858,066 - 37,859,565 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01232,443,657 - 32,446,127 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11232,696,661 - 32,699,160 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1232,696,670 - 32,699,160 (-)Ensemblpanpan1.1panPan2
SPRYD4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110720,099 - 722,139 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10720,046 - 722,119 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10783,303 - 785,354 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.010729,070 - 731,121 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl10729,026 - 732,353 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.110706,134 - 708,185 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.010949,239 - 951,290 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0101,072,964 - 1,075,015 (+)NCBIUU_Cfam_GSD_1.0
Spryd4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,044,244 - 58,046,508 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936646823,682 - 828,266 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936646823,724 - 825,659 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPRYD4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,804,394 - 21,816,681 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,804,345 - 21,816,760 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2523,527,854 - 23,529,936 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SPRYD4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,427,903 - 52,429,407 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1152,427,919 - 52,428,958 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037193,552,056 - 193,554,563 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spryd4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480211,559,820 - 11,561,942 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480211,559,817 - 11,561,852 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SPRYD4
22 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic|likely pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
NM_013267.4(GLS2):c.1411C>T (p.Arg471Trp) single nucleotide variant not specified [RCV004326959] Chr12:56473266 [GRCh38]
Chr12:56867050 [GRCh37]
Chr12:12q13.3
uncertain significance
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3 copy number gain not provided [RCV000750253] Chr12:621220..133779118 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
NM_013267.4(GLS2):c.929+3A>G single nucleotide variant not provided [RCV000841425] Chr12:56475621 [GRCh38]
Chr12:56869405 [GRCh37]
Chr12:12q13.3
likely benign
NM_013267.4(GLS2):c.1589G>A (p.Gly530Glu) single nucleotide variant not specified [RCV004324739] Chr12:56471836 [GRCh38]
Chr12:56865620 [GRCh37]
Chr12:12q13.3
uncertain significance
NM_013267.4(GLS2):c.1011G>A (p.Gly337=) single nucleotide variant not provided [RCV000963967] Chr12:56474882 [GRCh38]
Chr12:56868666 [GRCh37]
Chr12:12q13.3
benign
GRCh37/hg19 12q13.2-14.1(chr12:55552371-62126304)x3 copy number gain not provided [RCV001006505] Chr12:55552371..62126304 [GRCh37]
Chr12:12q13.2-14.1
pathogenic
GRCh37/hg19 12q13.2-13.3(chr12:56333262-57010442) copy number gain not specified [RCV002052997] Chr12:56333262..57010442 [GRCh37]
Chr12:12q13.2-13.3
uncertain significance
Single allele duplication not specified [RCV002286382] Chr12:55986511..56885590 [GRCh38]
Chr12:12q13.2-13.3
uncertain significance
NM_207344.4(SPRYD4):c.106G>A (p.Glu36Lys) single nucleotide variant not specified [RCV004111794] Chr12:56469059 [GRCh38]
Chr12:56862843 [GRCh37]
Chr12:12q13.3
uncertain significance
NM_013267.4(GLS2):c.898G>A (p.Gly300Arg) single nucleotide variant not specified [RCV004142053] Chr12:56475655 [GRCh38]
Chr12:56869439 [GRCh37]
Chr12:12q13.3
uncertain significance
NM_013267.4(GLS2):c.973G>A (p.Gly325Ser) single nucleotide variant not specified [RCV004208121] Chr12:56475067 [GRCh38]
Chr12:56868851 [GRCh37]
Chr12:12q13.3
uncertain significance
NM_013267.4(GLS2):c.1084G>A (p.Val362Ile) single nucleotide variant not specified [RCV004092149] Chr12:56474684 [GRCh38]
Chr12:56868468 [GRCh37]
Chr12:12q13.3
uncertain significance
NM_013267.4(GLS2):c.1258G>A (p.Ala420Thr) single nucleotide variant not specified [RCV004169104] Chr12:56473561 [GRCh38]
Chr12:56867345 [GRCh37]
Chr12:12q13.3
uncertain significance
NM_013267.4(GLS2):c.1741C>T (p.Leu581Phe) single nucleotide variant not specified [RCV004080140] Chr12:56471555 [GRCh38]
Chr12:56865339 [GRCh37]
Chr12:12q13.3
uncertain significance
NM_207344.4(SPRYD4):c.359G>A (p.Arg120His) single nucleotide variant not specified [RCV004251183] Chr12:56469312 [GRCh38]
Chr12:56863096 [GRCh37]
Chr12:12q13.3
uncertain significance
NM_013267.4(GLS2):c.683T>C (p.Ile228Thr) single nucleotide variant not specified [RCV004318256] Chr12:56478028 [GRCh38]
Chr12:56871812 [GRCh37]
Chr12:12q13.3
uncertain significance
NM_013267.4(GLS2):c.910A>G (p.Met304Val) single nucleotide variant not specified [RCV004350354] Chr12:56475643 [GRCh38]
Chr12:56869427 [GRCh37]
Chr12:12q13.3
uncertain significance
NM_013267.4(GLS2):c.757A>C (p.Lys253Gln) single nucleotide variant not specified [RCV004360414] Chr12:56477954 [GRCh38]
Chr12:56871738 [GRCh37]
Chr12:12q13.3
uncertain significance
NM_013267.4(GLS2):c.756C>G (p.Asn252Lys) single nucleotide variant not specified [RCV004360413] Chr12:56477955 [GRCh38]
Chr12:56871739 [GRCh37]
Chr12:12q13.3
uncertain significance
NM_013267.4(GLS2):c.1101C>T (p.Leu367=) single nucleotide variant not provided [RCV003390262] Chr12:56474667 [GRCh38]
Chr12:56868451 [GRCh37]
Chr12:12q13.3
likely benign
NM_013267.4(GLS2):c.496C>T (p.Arg166Cys) single nucleotide variant not specified [RCV004393249] Chr12:56479090 [GRCh38]
Chr12:56872874 [GRCh37]
Chr12:12q13.3
uncertain significance
NM_013267.4(GLS2):c.959G>A (p.Arg320Gln) single nucleotide variant not specified [RCV004393251] Chr12:56475081 [GRCh38]
Chr12:56868865 [GRCh37]
Chr12:12q13.3
uncertain significance
NM_207344.4(SPRYD4):c.512C>T (p.Ser171Phe) single nucleotide variant not specified [RCV004465308] Chr12:56469465 [GRCh38]
Chr12:56863249 [GRCh37]
Chr12:12q13.3
uncertain significance
NM_013267.4(GLS2):c.698T>G (p.Leu233Arg) single nucleotide variant not specified [RCV004393250] Chr12:56478013 [GRCh38]
Chr12:56871797 [GRCh37]
Chr12:12q13.3
uncertain significance
NM_013267.4(GLS2):c.1448G>A (p.Arg483Gln) single nucleotide variant not specified [RCV004393247] Chr12:56473229 [GRCh38]
Chr12:56867013 [GRCh37]
Chr12:12q13.3
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:705
Count of miRNA genes:500
Interacting mature miRNAs:553
Transcripts:ENST00000338146
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH93044  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371256,864,533 - 56,864,653UniSTSGRCh37
Build 361255,150,800 - 55,150,920RGDNCBI36
Celera1256,517,902 - 56,518,022RGD
Cytogenetic Map12q13UniSTS
Cytogenetic Map12q13.3UniSTS
HuRef1253,903,576 - 53,903,696UniSTS
GeneMap99-GB4 RH Map12252.1UniSTS
RH93492  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371256,864,872 - 56,864,992UniSTSGRCh37
Build 361255,151,139 - 55,151,259RGDNCBI36
Celera1256,518,241 - 56,518,361RGD
Cytogenetic Map12q13UniSTS
Cytogenetic Map12q13.3UniSTS
HuRef1253,903,915 - 53,904,035UniSTS
GeneMap99-GB4 RH Map12252.42UniSTS
A006P42  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371256,864,763 - 56,864,869UniSTSGRCh37
Build 361255,151,030 - 55,151,136RGDNCBI36
Celera1256,518,132 - 56,518,238RGD
Cytogenetic Map12q13UniSTS
Cytogenetic Map12q13.3UniSTS
HuRef1253,903,806 - 53,903,912UniSTS
GeneMap99-GB4 RH Map12249.21UniSTS
RH70287  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371256,863,509 - 56,863,687UniSTSGRCh37
Build 361255,149,776 - 55,149,954RGDNCBI36
Celera1256,516,878 - 56,517,056RGD
Cytogenetic Map12q13.3UniSTS
HuRef1253,902,550 - 53,902,730UniSTS
GeneMap99-GB4 RH Map12252.42UniSTS
NCBI RH Map12458.1UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 96 1 489 402 186 403 45 6 293 226 195 156 4
Low 2337 2750 1235 220 1562 61 4310 2152 3350 193 1255 1451 172 1204 2784 5
Below cutoff 1 237 2 201 1 36 84 5 4 2 1 1

Sequence


RefSeq Acc Id: ENST00000338146   ⟹   ENSP00000338034
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1256,468,578 - 56,479,708 (+)Ensembl
RefSeq Acc Id: NM_207344   ⟹   NP_997227
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381256,468,578 - 56,479,708 (+)NCBI
GRCh371256,862,301 - 56,864,769 (+)RGD
Build 361255,148,629 - 55,150,067 (+)NCBI Archive
Celera1256,515,670 - 56,518,138 (+)RGD
HuRef1253,901,342 - 53,903,812 (+)RGD
CHM1_11256,829,960 - 56,832,430 (+)NCBI
T2T-CHM13v2.01256,436,289 - 56,447,410 (+)NCBI
Sequence:
RefSeq Acc Id: NP_997227   ⟸   NM_207344
- UniProtKB: A8K7A5 (UniProtKB/Swiss-Prot),   Q8WW59 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000338034   ⟸   ENST00000338146
Protein Domains
B30.2/SPRY

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8WW59-F1-model_v2 AlphaFold Q8WW59 1-207 view protein structure

Promoters
RGD ID:6790513
Promoter ID:HG_KWN:15912
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_207344
Position:
Human AssemblyChrPosition (strand)Source
Build 361255,148,341 - 55,148,841 (+)MPROMDB
RGD ID:7224437
Promoter ID:EPDNEW_H17964
Type:initiation region
Name:SPRYD4_1
Description:SPRY domain containing 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381256,468,578 - 56,468,638EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:27468 AgrOrtholog
COSMIC SPRYD4 COSMIC
Ensembl Genes ENSG00000176422 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000338146 ENTREZGENE
  ENST00000338146.7 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.920 UniProtKB/Swiss-Prot
GTEx ENSG00000176422 GTEx
HGNC ID HGNC:27468 ENTREZGENE
Human Proteome Map SPRYD4 Human Proteome Map
InterPro B30.2/SPRY UniProtKB/Swiss-Prot
  B30.2/SPRY_sf UniProtKB/Swiss-Prot
  Butyrophylin_SPRY UniProtKB/Swiss-Prot
  ConA-like_dom_sf UniProtKB/Swiss-Prot
  SPRY_dom UniProtKB/Swiss-Prot
KEGG Report hsa:283377 UniProtKB/Swiss-Prot
NCBI Gene 283377 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED UniProtKB/Swiss-Prot
  RING-TYPE E3 UBIQUITIN TRANSFERASE UniProtKB/Swiss-Prot
Pfam SPRY UniProtKB/Swiss-Prot
PharmGKB PA143485622 PharmGKB
PRINTS BUTYPHLNCDUF UniProtKB/Swiss-Prot
PROSITE B302_SPRY UniProtKB/Swiss-Prot
SMART SPRY UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49899 UniProtKB/Swiss-Prot
UniProt A8K7A5 ENTREZGENE
  Q8WW59 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A8K7A5 UniProtKB/Swiss-Prot