Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | RTL8A | Human | (+)-schisandrin B | multiple interactions | ISO | Rtl8a (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of RTL8A mRNA] | CTD | PMID:31150632 | RTL8A | Human | (-)-alpha-phellandrene | increases expression | EXP | | 6480464 | alpha phellandrene results in increased expression of RTL8A mRNA | CTD | PMID:25075043 | RTL8A | Human | 17alpha-ethynylestradiol | affects expression | ISO | Rtl8a (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of RTL8A mRNA | CTD | PMID:17555576 | RTL8A | Human | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Rtl8a (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RTL8A mRNA | CTD | PMID:33387578 | RTL8A | Human | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Rtl8a (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of RTL8A mRNA | CTD | PMID:20188158 | RTL8A | Human | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of RTL8A mRNA | CTD | PMID:28628672 | RTL8A | Human | alpha-phellandrene | increases expression | EXP | | 6480464 | alpha phellandrene results in increased expression of RTL8A mRNA | CTD | PMID:25075043 | RTL8A | Human | antirheumatic drug | increases expression | EXP | | 6480464 | Antirheumatic Agents results in increased expression of RTL8A mRNA | CTD | PMID:24449571 | RTL8A | Human | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of RTL8A promoter | CTD | PMID:27901495 | RTL8A | Human | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of RTL8A 3' UTR and Benzo(a)pyrene results in increased methylation of RTL8A 5' UTR | CTD | PMID:27901495 | RTL8A | Human | benzo[b]fluoranthene | increases expression | ISO | Rtl8a (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of RTL8A mRNA | CTD | PMID:26377693 | RTL8A | Human | bisphenol A | increases expression | ISO | Rtl8a (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of RTL8A mRNA | CTD | PMID:34947998 | RTL8A | Human | bisphenol A | increases expression | ISO | Rtl8a (Mus musculus) | 6480464 | bisphenol A results in increased expression of RTL8A mRNA | CTD | PMID:35479511 | RTL8A | Human | bisphenol F | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of RTL8A mRNA | CTD | PMID:28628672 | RTL8A | Human | cadmium dichloride | decreases expression | ISO | Rtl8a (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased expression of RTL8A mRNA | CTD | PMID:33453195 | RTL8A | Human | carbon nanotube | increases expression | ISO | Rtl8a (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in increased expression of RTL8A mRNA | CTD | PMID:25554681 | RTL8A | Human | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of RTL8A mRNA | CTD | PMID:19320972 | RTL8A | Human | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of RTL8A mRNA | CTD | PMID:20106945 | RTL8A | Human | dexamethasone | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of RTL8A mRNA | CTD | PMID:28628672 | RTL8A | Human | dibenz[a,h]anthracene | increases expression | ISO | Rtl8a (Mus musculus) | 6480464 | 1 more ... | CTD | PMID:26377693 | RTL8A | Human | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of RTL8A mRNA | CTD | PMID:29803840 | RTL8A | Human | elemental selenium | multiple interactions | EXP | | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of RTL8A mRNA | CTD | PMID:19244175 | RTL8A | Human | ethanol | affects expression | ISO | Rtl8a (Mus musculus) | 6480464 | Ethanol affects the expression of RTL8A mRNA | CTD | PMID:30319688 | RTL8A | Human | ethanol | increases expression | ISO | Rtl8a (Mus musculus) | 6480464 | Ethanol results in increased expression of RTL8A mRNA | CTD | PMID:30319688 | RTL8A | Human | fenthion | increases expression | ISO | Rtl8a (Mus musculus) | 6480464 | Fenthion results in increased expression of RTL8A mRNA | CTD | PMID:34813904 | RTL8A | Human | gentamycin | decreases expression | ISO | Rtl8a (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of RTL8A mRNA | CTD | PMID:33387578 | RTL8A | Human | hydrogen peroxide | affects expression | EXP | | 6480464 | Hydrogen Peroxide affects the expression of RTL8A mRNA | CTD | PMID:21179406 | RTL8A | Human | indometacin | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of RTL8A mRNA | CTD | PMID:28628672 | RTL8A | Human | microcystin RR | decreases expression | EXP | | 6480464 | microcystin RR results in decreased expression of RTL8A protein | CTD | PMID:19111056 | RTL8A | Human | ozone | multiple interactions | ISO | Rtl8a (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of RTL8A mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of RTL8A mRNA | CTD | PMID:34911549 | RTL8A | Human | paracetamol | affects expression | ISO | Rtl8a (Mus musculus) | 6480464 | Acetaminophen affects the expression of RTL8A mRNA | CTD | PMID:17562736 | RTL8A | Human | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of RTL8A mRNA | CTD | PMID:29067470 | RTL8A | Human | selenium atom | multiple interactions | EXP | | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of RTL8A mRNA | CTD | PMID:19244175 | RTL8A | Human | tamoxifen | affects expression | ISO | Rtl8a (Mus musculus) | 6480464 | Tamoxifen affects the expression of RTL8A mRNA | CTD | PMID:17555576 | RTL8A | Human | tetrachloromethane | decreases expression | ISO | Rtl8a (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of RTL8A mRNA | CTD | PMID:31150632 | RTL8A | Human | tetrachloromethane | multiple interactions | ISO | Rtl8a (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of RTL8A mRNA] | CTD | PMID:31150632 | RTL8A | Human | thimerosal | decreases expression | EXP | | 6480464 | Thimerosal results in decreased expression of RTL8A mRNA | CTD | PMID:27188386 | RTL8A | Human | thioacetamide | decreases expression | ISO | Rtl8a (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of RTL8A mRNA | CTD | PMID:34492290 | RTL8A | Human | titanium dioxide | increases expression | ISO | Rtl8a (Mus musculus) | 6480464 | titanium dioxide results in increased expression of RTL8A mRNA | CTD | PMID:29264374 | RTL8A | Human | trichloroethene | decreases expression | ISO | Rtl8a (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased expression of RTL8A mRNA | CTD | PMID:33387578 | RTL8A | Human | valproic acid | decreases methylation | EXP | | 6480464 | Valproic Acid results in decreased methylation of RTL8A gene | CTD | PMID:29154799 | RTL8A | Human | vitamin E | increases expression | EXP | | 6480464 | Vitamin E results in increased expression of RTL8A mRNA | CTD | PMID:19244175 | RTL8A | Human | vitamin E | multiple interactions | EXP | | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of RTL8A mRNA | CTD | PMID:19244175 | RTL8A | Human | XL147 | multiple interactions | ISO | Rtl8a (Mus musculus) | 6480464 | XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of RTL8A mRNA] | CTD | PMID:29891994 | |