RPAP3 (RNA polymerase II associated protein 3) - Rat Genome Database

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Gene: RPAP3 (RNA polymerase II associated protein 3) Homo sapiens
Analyze
Symbol: RPAP3
Name: RNA polymerase II associated protein 3
RGD ID: 1603005
HGNC Page HGNC:26151
Description: Located in RPAP3/R2TP/prefoldin-like complex; cytosol; and protein folding chaperone complex. Part of R2TP complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: FLJ21908; hSpagh; RNA polymerase II-associated protein 3; Tah1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381247,661,249 - 47,706,030 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1247,661,249 - 47,706,030 (-)EnsemblGRCh38hg38GRCh38
GRCh371248,055,032 - 48,099,813 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361246,343,341 - 46,386,041 (-)NCBINCBI36Build 36hg18NCBI36
Celera1246,853,186 - 46,897,316 (-)NCBICelera
Cytogenetic Map12q13.11NCBI
HuRef1245,086,823 - 45,130,955 (-)NCBIHuRef
CHM1_11248,021,629 - 48,065,751 (-)NCBICHM1_1
T2T-CHM13v2.01247,622,569 - 47,667,355 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14676191   PMID:15761153   PMID:16055720   PMID:16344560   PMID:17643375   PMID:18538670   PMID:19180575   PMID:19450687   PMID:19875381   PMID:19953087   PMID:20098747  
PMID:20371770   PMID:20801936   PMID:20864032   PMID:20864038   PMID:21044950   PMID:21078300   PMID:21145461   PMID:21184742   PMID:21360678   PMID:21415862   PMID:21832049   PMID:21873635  
PMID:22939629   PMID:22990118   PMID:23159623   PMID:23667685   PMID:23940030   PMID:24366813   PMID:24510904   PMID:24550385   PMID:24794838   PMID:24965446   PMID:24981860   PMID:25036637  
PMID:25071155   PMID:25241763   PMID:25277244   PMID:25404746   PMID:25515538   PMID:25544563   PMID:25659891   PMID:25921289   PMID:26186194   PMID:26344197   PMID:26496610   PMID:26549023  
PMID:26638075   PMID:26673895   PMID:26711270   PMID:26972000   PMID:27173435   PMID:27432908   PMID:27780869   PMID:27880917   PMID:28330616   PMID:28514442   PMID:28515276   PMID:28561026  
PMID:28718761   PMID:29229926   PMID:29395067   PMID:29467282   PMID:29513927   PMID:29662061   PMID:30033218   PMID:30344098   PMID:31048545   PMID:31519766   PMID:31586073   PMID:31617661  
PMID:31738558   PMID:31762063   PMID:32640226   PMID:32707033   PMID:32877691   PMID:32912968   PMID:33397691   PMID:33417871   PMID:33536335   PMID:33742100   PMID:33916271   PMID:33957083  
PMID:33961781   PMID:34079125   PMID:34373451   PMID:34672954   PMID:34709266   PMID:34709727   PMID:34795231   PMID:35007762   PMID:35032548   PMID:35271311   PMID:35439318   PMID:35831314  
PMID:35944360   PMID:36114006   PMID:36215168   PMID:36232890   PMID:36526897   PMID:36674791   PMID:37151849   PMID:37827155   PMID:38280479  


Genomics

Comparative Map Data
RPAP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381247,661,249 - 47,706,030 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1247,661,249 - 47,706,030 (-)EnsemblGRCh38hg38GRCh38
GRCh371248,055,032 - 48,099,813 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361246,343,341 - 46,386,041 (-)NCBINCBI36Build 36hg18NCBI36
Celera1246,853,186 - 46,897,316 (-)NCBICelera
Cytogenetic Map12q13.11NCBI
HuRef1245,086,823 - 45,130,955 (-)NCBIHuRef
CHM1_11248,021,629 - 48,065,751 (-)NCBICHM1_1
T2T-CHM13v2.01247,622,569 - 47,667,355 (-)NCBIT2T-CHM13v2.0
Rpap3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391597,572,978 - 97,603,746 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1597,572,978 - 97,603,706 (-)EnsemblGRCm39 Ensembl
GRCm381597,675,097 - 97,705,822 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1597,675,097 - 97,705,825 (-)EnsemblGRCm38mm10GRCm38
MGSCv371597,505,536 - 97,536,253 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361597,503,139 - 97,533,856 (-)NCBIMGSCv36mm8
Celera1599,802,797 - 99,833,872 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1553.54NCBI
Rpap3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87130,689,923 - 130,719,411 (-)NCBIGRCr8
mRatBN7.27128,810,820 - 128,840,006 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7128,810,827 - 128,839,950 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7130,607,902 - 130,635,622 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07132,833,436 - 132,861,156 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07132,745,891 - 132,773,611 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07139,167,302 - 139,196,468 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7139,167,303 - 139,196,416 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07139,359,664 - 139,386,634 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47136,382,843 - 136,415,654 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17136,459,279 - 136,492,091 (-)NCBI
Celera7125,302,242 - 125,329,913 (-)NCBICelera
Cytogenetic Map7q36NCBI
Rpap3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555006,585,969 - 6,595,219 (-)NCBIChiLan1.0ChiLan1.0
RPAP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21046,462,129 - 46,508,651 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11246,458,886 - 46,505,093 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01241,027,791 - 41,074,925 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11241,901,843 - 41,947,756 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1241,901,843 - 41,947,756 (+)Ensemblpanpan1.1panPan2
RPAP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1277,060,179 - 7,097,417 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl277,059,154 - 7,097,233 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2739,209,667 - 39,251,044 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0277,124,127 - 7,165,693 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl277,124,155 - 7,167,544 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1277,060,569 - 7,102,121 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0277,095,929 - 7,137,295 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02739,491,245 - 39,539,227 (-)NCBIUU_Cfam_GSD_1.0
Rpap3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494567,561,159 - 67,596,324 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365125,568,500 - 5,603,654 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365125,568,500 - 5,603,613 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPAP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl578,032,748 - 78,066,224 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1577,968,171 - 78,066,252 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RPAP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11143,887,992 - 43,926,720 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1143,885,062 - 43,926,709 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037202,454,886 - 202,495,018 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rpap3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248164,578,769 - 4,611,647 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248164,578,749 - 4,620,038 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RPAP3
26 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic|likely pathogenic
GRCh37/hg19 12p11.21-q13.12(chr12:31886971-50360461)x3 copy number gain See cases [RCV000207454] Chr12:31886971..50360461 [GRCh37]
Chr12:12p11.21-q13.12		 pathogenic
GRCh37/hg19 12q11-13.12(chr12:37857750-49791459)x3 copy number gain See cases [RCV000448835] Chr12:37857750..49791459 [GRCh37]
Chr12:12q11-13.12		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
NM_024604.3(RPAP3):c.1750A>G (p.Lys584Glu) single nucleotide variant not specified [RCV004315113] Chr12:47667815 [GRCh38]
Chr12:48061598 [GRCh37]
Chr12:12q13.11		 uncertain significance
NC_000012.11:g.26370251_54361538inv inversion not specified [RCV000714265] Chr12:26370251..54361538 [GRCh37]
Chr12:12p12.1-q13.13		 uncertain significance
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3 copy number gain not provided [RCV000750253] Chr12:621220..133779118 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
NM_024604.3(RPAP3):c.1864A>G (p.Lys622Glu) single nucleotide variant not specified [RCV004322354] Chr12:47667028 [GRCh38]
Chr12:48060811 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.862C>T (p.Arg288Trp) single nucleotide variant not specified [RCV004326394] Chr12:47687878 [GRCh38]
Chr12:48081661 [GRCh37]
Chr12:12q13.11		 uncertain significance
GRCh37/hg19 12q11-13.12(chr12:37873948-49578619)x3 copy number gain See cases [RCV001353185] Chr12:37873948..49578619 [GRCh37]
Chr12:12q11-13.12		 likely pathogenic
GRCh37/hg19 12q11-13.12(chr12:37857750-49791459) copy number gain not specified [RCV002052988] Chr12:37857750..49791459 [GRCh37]
Chr12:12q11-13.12		 pathogenic
GRCh37/hg19 12q12-13.11(chr12:44661149-48921204)x1 copy number loss not provided [RCV002291537] Chr12:44661149..48921204 [GRCh37]
Chr12:12q12-13.11		 pathogenic
NM_024604.3(RPAP3):c.928G>A (p.Ala310Thr) single nucleotide variant not specified [RCV004202677] Chr12:47686844 [GRCh38]
Chr12:48080627 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1865A>G (p.Lys622Arg) single nucleotide variant not specified [RCV004088276] Chr12:47667027 [GRCh38]
Chr12:48060810 [GRCh37]
Chr12:12q13.11		 likely benign
NM_024604.3(RPAP3):c.343C>G (p.Leu115Val) single nucleotide variant not specified [RCV004156801] Chr12:47697671 [GRCh38]
Chr12:48091454 [GRCh37]
Chr12:12q13.11		 likely benign
NM_024604.3(RPAP3):c.1276C>T (p.Pro426Ser) single nucleotide variant not specified [RCV004127277] Chr12:47679504 [GRCh38]
Chr12:48073287 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1463C>T (p.Thr488Ile) single nucleotide variant not specified [RCV004174299] Chr12:47670170 [GRCh38]
Chr12:48063953 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.367G>A (p.Glu123Lys) single nucleotide variant not specified [RCV004094247] Chr12:47697647 [GRCh38]
Chr12:48091430 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1855T>C (p.Ser619Pro) single nucleotide variant not specified [RCV004074883] Chr12:47667037 [GRCh38]
Chr12:48060820 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.326A>G (p.Asp109Gly) single nucleotide variant not specified [RCV004113322] Chr12:47697688 [GRCh38]
Chr12:48091471 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.487G>A (p.Asp163Asn) single nucleotide variant not specified [RCV004137313] Chr12:47696334 [GRCh38]
Chr12:48090117 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1453C>T (p.Leu485Phe) single nucleotide variant not specified [RCV004182965] Chr12:47670180 [GRCh38]
Chr12:48063963 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1462A>C (p.Thr488Pro) single nucleotide variant not specified [RCV004249487] Chr12:47670171 [GRCh38]
Chr12:48063954 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1960A>G (p.Ser654Gly) single nucleotide variant not specified [RCV004267016] Chr12:47663543 [GRCh38]
Chr12:48057326 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1372C>T (p.Pro458Ser) single nucleotide variant not specified [RCV004252111] Chr12:47670261 [GRCh38]
Chr12:48064044 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1549G>A (p.Asp517Asn) single nucleotide variant not specified [RCV004323267] Chr12:47669080 [GRCh38]
Chr12:48062863 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.324C>A (p.Asp108Glu) single nucleotide variant not specified [RCV004336554] Chr12:47697690 [GRCh38]
Chr12:48091473 [GRCh37]
Chr12:12q13.11		 likely benign
NM_024604.3(RPAP3):c.1401T>G (p.Asn467Lys) single nucleotide variant not specified [RCV004310225] Chr12:47670232 [GRCh38]
Chr12:48064015 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1032A>T (p.Leu344Phe) single nucleotide variant not specified [RCV004308622] Chr12:47681778 [GRCh38]
Chr12:48075561 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1653G>T (p.Gln551His) single nucleotide variant not specified [RCV004071461] Chr12:47668976 [GRCh38]
Chr12:48062759 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.298C>T (p.Arg100Cys) single nucleotide variant not specified [RCV004217369] Chr12:47697716 [GRCh38]
Chr12:48091499 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1685C>G (p.Ser562Cys) single nucleotide variant not specified [RCV004365606] Chr12:47668944 [GRCh38]
Chr12:48062727 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.607G>C (p.Ala203Pro) single nucleotide variant not specified [RCV004354896] Chr12:47690578 [GRCh38]
Chr12:48084361 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1306A>T (p.Ile436Phe) single nucleotide variant not specified [RCV004347353] Chr12:47670327 [GRCh38]
Chr12:48064110 [GRCh37]
Chr12:12q13.11		 uncertain significance
GRCh37/hg19 12q12-13.11(chr12:38258635-48235837)x3 copy number gain not specified [RCV003987001] Chr12:38258635..48235837 [GRCh37]
Chr12:12q12-13.11		 pathogenic
NM_024604.3(RPAP3):c.1253A>C (p.Lys418Thr) single nucleotide variant not specified [RCV004449756] Chr12:47679527 [GRCh38]
Chr12:48073310 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1309A>C (p.Ile437Leu) single nucleotide variant not specified [RCV004449757] Chr12:47670324 [GRCh38]
Chr12:48064107 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1322G>A (p.Gly441Asp) single nucleotide variant not specified [RCV004449758] Chr12:47670311 [GRCh38]
Chr12:48064094 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1568G>A (p.Ser523Asn) single nucleotide variant not specified [RCV004449759] Chr12:47669061 [GRCh38]
Chr12:48062844 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1628C>T (p.Pro543Leu) single nucleotide variant not specified [RCV004449760] Chr12:47669001 [GRCh38]
Chr12:48062784 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.1696T>G (p.Leu566Val) single nucleotide variant not specified [RCV004449761] Chr12:47668933 [GRCh38]
Chr12:48062716 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.349C>G (p.Gln117Glu) single nucleotide variant not specified [RCV004449763] Chr12:47697665 [GRCh38]
Chr12:48091448 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.478A>T (p.Met160Leu) single nucleotide variant not specified [RCV004449764] Chr12:47696343 [GRCh38]
Chr12:48090126 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.98A>G (p.Lys33Arg) single nucleotide variant not specified [RCV004449765] Chr12:47702743 [GRCh38]
Chr12:48096526 [GRCh37]
Chr12:12q13.11		 uncertain significance
NM_024604.3(RPAP3):c.211G>C (p.Glu71Gln) single nucleotide variant not specified [RCV004337580] Chr12:47701547 [GRCh38]
Chr12:48095330 [GRCh37]
Chr12:12q13.11		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:450
Count of miRNA genes:329
Interacting mature miRNAs:342
Transcripts:ENST00000005386, ENST00000380650, ENST00000432584, ENST00000547706, ENST00000548211, ENST00000548296, ENST00000551293
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
WI-16433  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371248,055,754 - 48,055,881UniSTSGRCh37
Build 361246,342,021 - 46,342,148RGDNCBI36
Celera1246,853,225 - 46,853,352RGD
Cytogenetic Map12q13.11UniSTS
HuRef1245,086,862 - 45,086,989UniSTS
GeneMap99-GB4 RH Map12201.66UniSTS
Whitehead-RH Map12293.7UniSTS
NCBI RH Map12357.8UniSTS
D12S2170  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371248,093,984 - 48,094,097UniSTSGRCh37
Build 361246,380,251 - 46,380,364RGDNCBI36
Celera1246,891,456 - 46,891,569RGD
Cytogenetic Map12q13.11UniSTS
HuRef1245,125,096 - 45,125,209UniSTS
WIAF-1692  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371248,056,094 - 48,056,296UniSTSGRCh37
Build 361246,342,361 - 46,342,563RGDNCBI36
Celera1246,853,565 - 46,853,767RGD
Cytogenetic Map12q13.11UniSTS
HuRef1245,087,202 - 45,087,404UniSTS
GeneMap99-GB4 RH Map12211.47UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1066 750 756 175 980 126 2054 701 1396 258 1251 942 66 1 342 1412 5 2
Low 1373 2201 970 449 946 339 2303 1481 2338 161 209 671 109 862 1376 1
Below cutoff 40 25 15

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000005386   ⟹   ENSP00000005386
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1247,661,249 - 47,706,030 (-)Ensembl
RefSeq Acc Id: ENST00000380650   ⟹   ENSP00000370024
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1247,663,293 - 47,705,986 (-)Ensembl
RefSeq Acc Id: ENST00000432584   ⟹   ENSP00000401823
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1247,663,292 - 47,706,026 (-)Ensembl
RefSeq Acc Id: ENST00000547706
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1247,700,015 - 47,702,816 (-)Ensembl
RefSeq Acc Id: ENST00000548211
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1247,663,290 - 47,664,843 (-)Ensembl
RefSeq Acc Id: ENST00000548296
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1247,695,942 - 47,697,701 (-)Ensembl
RefSeq Acc Id: ENST00000551293
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1247,701,191 - 47,705,999 (-)Ensembl
RefSeq Acc Id: NM_001146075   ⟹   NP_001139547
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381247,661,249 - 47,706,030 (-)NCBI
GRCh371248,055,715 - 48,099,844 (-)RGD
Celera1246,853,186 - 46,897,316 (-)RGD
HuRef1245,086,823 - 45,130,955 (-)RGD
CHM1_11248,021,629 - 48,065,751 (-)NCBI
T2T-CHM13v2.01247,622,569 - 47,667,355 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001146076   ⟹   NP_001139548
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381247,661,249 - 47,706,030 (-)NCBI
GRCh371248,055,715 - 48,099,844 (-)RGD
Celera1246,853,186 - 46,897,316 (-)RGD
HuRef1245,086,823 - 45,130,955 (-)RGD
CHM1_11248,021,629 - 48,065,751 (-)NCBI
T2T-CHM13v2.01247,622,569 - 47,667,355 (-)NCBI
Sequence:
RefSeq Acc Id: NM_024604   ⟹   NP_078880
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381247,661,249 - 47,706,030 (-)NCBI
GRCh371248,055,715 - 48,099,844 (-)RGD
Build 361246,343,341 - 46,386,041 (-)NCBI Archive
Celera1246,853,186 - 46,897,316 (-)RGD
HuRef1245,086,823 - 45,130,955 (-)RGD
CHM1_11248,021,629 - 48,065,751 (-)NCBI
T2T-CHM13v2.01247,622,569 - 47,667,355 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_078880   ⟸   NM_024604
- Peptide Label: isoform 1
- UniProtKB: B4DRW9 (UniProtKB/Swiss-Prot),   Q6PHR5 (UniProtKB/Swiss-Prot),   Q9H6T3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001139547   ⟸   NM_001146075
- Peptide Label: isoform 2
- UniProtKB: Q9H6T3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001139548   ⟸   NM_001146076
- Peptide Label: isoform 3
- UniProtKB: Q9H6T3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000005386   ⟸   ENST00000005386
RefSeq Acc Id: ENSP00000401823   ⟸   ENST00000432584
RefSeq Acc Id: ENSP00000370024   ⟸   ENST00000380650

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9H6T3-F1-model_v2 AlphaFold Q9H6T3 1-665 view protein structure

Promoters
RGD ID:6790454
Promoter ID:HG_KWN:15456
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001146075,   NM_001146076,   NM_024604
Position:
Human AssemblyChrPosition (strand)Source
Build 361246,385,916 - 46,386,992 (-)MPROMDB
RGD ID:7223713
Promoter ID:EPDNEW_H17602
Type:initiation region
Name:RPAP3_1
Description:RNA polymerase II associated protein 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381247,706,006 - 47,706,066EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:26151 AgrOrtholog
COSMIC RPAP3 COSMIC
Ensembl Genes ENSG00000005175 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000005386 ENTREZGENE
  ENST00000005386.8 UniProtKB/Swiss-Prot
  ENST00000380650 ENTREZGENE
  ENST00000380650.4 UniProtKB/Swiss-Prot
  ENST00000432584 ENTREZGENE
  ENST00000432584.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot
GTEx ENSG00000005175 GTEx
HGNC ID HGNC:26151 ENTREZGENE
Human Proteome Map RPAP3 Human Proteome Map
InterPro RPAP3-like_C UniProtKB/Swiss-Prot
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot
  TPR_1 UniProtKB/Swiss-Prot
  TPR_repeat UniProtKB/Swiss-Prot
KEGG Report hsa:79657 UniProtKB/Swiss-Prot
NCBI Gene 79657 ENTREZGENE
OMIM 611477 OMIM
PANTHER RNA POLYMERASE II-ASSOCIATED PROTEIN 3 UniProtKB/Swiss-Prot
  RNA POLYMERASE II-ASSOCIATED PROTEIN 3 UniProtKB/Swiss-Prot
Pfam RPAP3_C UniProtKB/Swiss-Prot
  TPR_1 UniProtKB/Swiss-Prot
  TPR_16 UniProtKB/Swiss-Prot
  TPR_8 UniProtKB/Swiss-Prot
PharmGKB PA162401982 PharmGKB
PROSITE TPR UniProtKB/Swiss-Prot
  TPR_REGION UniProtKB/Swiss-Prot
SMART TPR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot
UniProt B4DRW9 ENTREZGENE
  Q6PHR5 ENTREZGENE
  Q9H6T3 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B4DRW9 UniProtKB/Swiss-Prot
  Q6PHR5 UniProtKB/Swiss-Prot