SNORA22 (small nucleolar RNA, H/ACA box 22) - Rat Genome Database

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Gene: SNORA22 (small nucleolar RNA, H/ACA box 22) Homo sapiens
Analyze
No known orthologs.
Symbol: SNORA22
Name: small nucleolar RNA, H/ACA box 22
RGD ID: 1602589
HGNC Page HGNC:32612
Description: Predicted to be involved in RNA processing. Predicted to be located in nucleolus; INTERACTS WITH 2-hydroxypropanoic acid; aflatoxin B1; bisphenol A.
Type: snorna
RefSeq Status: VALIDATED
Previously known as: ACA22; SNORA22A
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38765,755,526 - 65,755,659 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl765,755,526 - 65,755,659 (+)EnsemblGRCh38hg38GRCh38
GRCh37765,220,513 - 65,220,646 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36764,857,948 - 64,858,081 (+)NCBINCBI36Build 36hg18NCBI36
Celera758,335,933 - 58,336,066 (+)NCBICelera
Cytogenetic Map7q11.21NCBI
HuRef761,408,776 - 61,408,909 (+)NCBIHuRef
CHM1_1765,315,816 - 65,315,949 (+)NCBICHM1_1
T2T-CHM13v2.0766,977,656 - 66,977,789 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2764,558,033 - 64,558,166 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleolus  (IEA)

References
Additional References at PubMed
PMID:15199136   PMID:16381836   PMID:19446021  


Genomics


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1 copy number loss See cases [RCV000135401] Chr7:54185..159282390 [GRCh38]
Chr7:54185..159075079 [GRCh37]
Chr7:149268..158767840 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7q11.21(chr7:65039567-65804880)x1 copy number loss See cases [RCV000135810] Chr7:65039567..65804880 [GRCh38]
Chr7:64499945..65208605 [GRCh37]
Chr7:64137380..64907302 [NCBI36]
Chr7:7q11.21		 uncertain significance
GRCh38/hg38 7q11.21(chr7:65017875-65835330)x1 copy number loss See cases [RCV000139720] Chr7:65017875..65835330 [GRCh38]
Chr7:64478253..65300317 [GRCh37]
Chr7:64115688..64937752 [NCBI36]
Chr7:7q11.21		 likely benign
GRCh38/hg38 7q11.21-11.23(chr7:62977085-75415352)x3 copy number gain See cases [RCV000142242] Chr7:62977085..75415352 [GRCh38]
Chr7:62437463..75044630 [GRCh37]
Chr7:62074898..74882566 [NCBI36]
Chr7:7q11.21-11.23		 pathogenic
GRCh38/hg38 7q11.21-11.23(chr7:62736364-75432710)x1 copy number loss See cases [RCV000142528] Chr7:62736364..75432710 [GRCh38]
Chr7:62196742..75061986 [GRCh37]
Chr7:61834177..74899922 [NCBI36]
Chr7:7q11.21-11.23		 pathogenic
GRCh38/hg38 7q11.21(chr7:62977012-66848675) copy number gain See cases [RCV000143449] Chr7:62977012..66848675 [GRCh38]
Chr7:62437390..66313662 [GRCh37]
Chr7:62074825..65951097 [NCBI36]
Chr7:7q11.21		 likely pathogenic
GRCh38/hg38 7q11.21-11.22(chr7:64657050-72243063)x1 copy number loss See cases [RCV000050606] Chr7:64657050..72243063 [GRCh38]
Chr7:64117428..71708048 [GRCh37]
Chr7:63754863..71345984 [NCBI36]
Chr7:7q11.21-11.22		 pathogenic
GRCh38/hg38 7q11.21-11.22(chr7:62570287-67823956)x3 copy number gain See cases [RCV000050687] Chr7:62570287..67823956 [GRCh38]
Chr7:62030665..67288943 [GRCh37]
Chr7:61668100..66926378 [NCBI36]
Chr7:7q11.21-11.22		 pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1 copy number loss See cases [RCV000052250] Chr7:53985..159282531 [GRCh38]
Chr7:53985..159075220 [GRCh37]
Chr7:149068..158767981 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7q11.21-21.11(chr7:64560824-79186156)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052318]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052318]|See cases [RCV000052318] Chr7:64560824..79186156 [GRCh38]
Chr7:64021202..78815472 [GRCh37]
Chr7:63658637..78653408 [NCBI36]
Chr7:7q11.21-21.11		 pathogenic
GRCh38/hg38 7p12.1-q11.22(chr7:53274059-68576213)x3 copy number gain See cases [RCV000053534] Chr7:53274059..68576213 [GRCh38]
Chr7:53341752..68041200 [GRCh37]
Chr7:53309246..67679136 [NCBI36]
Chr7:7p12.1-q11.22		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:112
Count of miRNA genes:109
Interacting mature miRNAs:111
Transcripts:ENST00000383907
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High 1 1
Medium 11 8 5 130 6 16 19 1 17 32 1 1
Low 1882 850 1017 322 801 232 2321 862 1618 231 935 1186 102 691 1196 3
Below cutoff 349 855 382 153 224 105 932 544 1110 72 261 220 48 324 666

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000383907
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl765,755,526 - 65,755,659 (+)Ensembl
RefSeq Acc Id: NR_002961
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38765,755,526 - 65,755,659 (+)NCBI
GRCh37765,220,513 - 65,220,646 (+)RGD
Build 36764,857,948 - 64,858,081 (+)NCBI Archive
Celera758,335,933 - 58,336,066 (+)RGD
HuRef761,408,776 - 61,408,909 (+)ENTREZGENE
CHM1_1765,315,816 - 65,315,949 (+)NCBI
T2T-CHM13v2.0766,977,656 - 66,977,789 (+)NCBI
CRA_TCAGchr7v2764,558,033 - 64,558,166 (+)ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC SNORA22 COSMIC
Ensembl Genes ENSG00000206634 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000383907 ENTREZGENE
GTEx ENSG00000206634 GTEx
HGNC ID HGNC:32612 ENTREZGENE
Human Proteome Map SNORA22 Human Proteome Map
NCBI Gene 677807 ENTREZGENE
PharmGKB PA144596346 PharmGKB
RNAcentral URS000028CE2F RNACentral