FAM110D (family with sequence similarity 110 member D)

Gene: FAM110D (family with sequence similarity 110 member D) Homo sapiens

Analyze

Symbol:

FAM110D

Name:

family with sequence similarity 110 member D

RGD ID:

1602464

HGNC Page

HGNC:25860

Description:

ASSOCIATED WITH autosomal recessive hypercholesterolemia; retinitis pigmentosa 59; INTERACTS WITH all-trans-retinoic acid; arsane; arsenic atom

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

family with sequence similarity 110, member D; FLJ14050; glycine/arginine rich protein 1; glycine/arginine-rich protein 1; GRRP1; RP11-96L14.5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	26,159,079 - 26,163,962 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	26,159,079 - 26,163,962 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	26,485,570 - 26,490,453 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	26,358,098 - 26,361,706 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	24,882,208 - 24,885,816 (+)	NCBI		Celera
Cytogenetic Map	1	p36.11	NCBI
HuRef	1	24,739,879 - 24,743,487 (+)	NCBI		HuRef
CHM1_1	1	26,598,737 - 26,602,345 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	25,996,509 - 26,001,393 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive hypercholesterolemia (IAGP)

retinitis pigmentosa 59 (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (ISO)

acrylamide (ISO)

all-trans-retinoic acid (EXP)

arsane (EXP)

arsenic atom (EXP)

benzo[a]pyrene (EXP,ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

choline (ISO)

chromium(6+) (ISO)

chrysene (ISO)

epoxiconazole (ISO)

folic acid (ISO)

fulvestrant (EXP)

isoprenaline (ISO)

ketamine (ISO)

L-methionine (ISO)

ozone (ISO)

paracetamol (ISO)

paraquat (ISO)

sunitinib (EXP)

tetraphene (ISO)

thioacetamide (ISO)

triclosan (EXP)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:14702039	PMID:16344560	PMID:33621312	PMID:33961781

Genomics

Comparative Map Data

FAM110D
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	26,159,079 - 26,163,962 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	26,159,079 - 26,163,962 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	26,485,570 - 26,490,453 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	26,358,098 - 26,361,706 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	24,882,208 - 24,885,816 (+)	NCBI		Celera
Cytogenetic Map	1	p36.11	NCBI
HuRef	1	24,739,879 - 24,743,487 (+)	NCBI		HuRef
CHM1_1	1	26,598,737 - 26,602,345 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	25,996,509 - 26,001,393 (+)	NCBI		T2T-CHM13v2.0

Fam110d
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	133,978,413 - 133,993,528 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	133,978,421 - 133,981,417 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	134,251,102 - 134,266,196 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	134,251,110 - 134,254,106 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	133,807,025 - 133,810,021 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	133,523,186 - 133,540,462 (-)	NCBI		MGSCv36	mm8
Celera	4	132,430,926 - 132,433,919 (-)	NCBI		Celera
Cytogenetic Map	4	D2.3	NCBI
cM Map	4	66.5	NCBI

Fam110d
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	151,754,773 - 151,757,743 (-)	NCBI		GRCr8
mRatBN7.2	5	146,471,048 - 146,474,019 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	146,471,049 - 146,474,056 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	149,173,025 - 149,175,988 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	150,943,194 - 150,946,157 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	150,929,239 - 150,932,202 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	152,470,898 - 152,473,903 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	152,470,905 - 152,473,868 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	156,229,913 - 156,232,912 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	152,996,110 - 152,999,073 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	144,888,738 - 144,891,701 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

Fam110d
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	5,603,203 - 5,605,815 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	5,603,203 - 5,605,815 (+)	NCBI	ChiLan1.0	ChiLan1.0

FAM110D
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	200,708,665 - 200,712,290 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	199,806,780 - 199,810,395 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	25,420,411 - 25,424,036 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	26,487,460 - 26,491,058 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

FAM110D
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	73,826,573 - 73,834,040 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	73,826,900 - 73,827,727 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	70,402,903 - 70,410,311 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	74,389,688 - 74,397,083 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	74,389,710 - 74,392,744 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	71,214,080 - 71,221,463 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	72,219,813 - 72,227,203 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	73,223,734 - 73,231,149 (-)	NCBI		UU_Cfam_GSD_1.0

Fam110d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	44,857,144 - 44,860,939 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	10,683,979 - 10,685,074 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	10,682,107 - 10,685,721 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FAM110D
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	83,581,362 - 83,584,444 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	83,581,341 - 83,584,444 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

FAM110D
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	106,605,468 - 106,610,006 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	106,606,018 - 106,606,836 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	9,810,036 - 9,813,674 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fam110d
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	10,211,953 - 10,214,647 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	10,180,642 - 10,215,199 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in FAM110D
13 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 1p36.11-34.2(chr1:24381206-41401517)x3	copy number gain	See cases [RCV000138891]	Chr1:24381206..41401517 [GRCh38] Chr1:24707696..41886350 [GRCh37] Chr1:24580283..41658937 [NCBI36] Chr1:1p36.11-34.2	pathogenic
GRCh37/hg19 1p36.12-12(chr1:20608823-120546301)x3	copy number loss	not provided [RCV000762767]	Chr1:20608823..120546301 [GRCh37] Chr1:1p36.12-12	likely benign
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3	copy number gain	See cases [RCV000510383]	Chr1:849467..249224684 [GRCh37] Chr1:1p36.33-q44	pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)	copy number gain	See cases [RCV000510926]	Chr1:849467..249224684 [GRCh37] Chr1:1p36.33-q44	pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3	copy number gain	not provided [RCV000736295]	Chr1:47851..249228449 [GRCh37] Chr1:1p36.33-q44	pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3	copy number gain	not provided [RCV000736305]	Chr1:82154..249218992 [GRCh37] Chr1:1p36.33-q44	pathogenic
GRCh37/hg19 1p36.22-21.1(chr1:103343285-103455144)x3	copy number gain	Global developmental delay [RCV000787285]	Chr1:103343285..103455144 [GRCh37] Chr1:1p36.22-21.1	uncertain significance
NC_000001.10:g.(?_25870180)_(26795632_?)del	deletion	Hypercholesterolemia, familial, 4 [RCV001385284]	Chr1:25870180..26795632 [GRCh37] Chr1:1p36.11	pathogenic
GRCh37/hg19 1p36.11(chr1:26246213-27044118)x3	copy number gain	not provided [RCV001829142]	Chr1:26246213..27044118 [GRCh37] Chr1:1p36.11	uncertain significance
NC_000001.10:g.(?_25870190)_(27278871_?)dup	duplication	Retinitis pigmentosa 59 [RCV003122734]	Chr1:25870190..27278871 [GRCh37] Chr1:1p36.11	uncertain significance
NM_024869.3(FAM110D):c.200C>T (p.Pro67Leu)	single nucleotide variant	not specified [RCV004182215]	Chr1:26161491 [GRCh38] Chr1:26487982 [GRCh37] Chr1:1p36.11	uncertain significance
NM_024869.3(FAM110D):c.725C>T (p.Pro242Leu)	single nucleotide variant	not specified [RCV004133146]	Chr1:26162016 [GRCh38] Chr1:26488507 [GRCh37] Chr1:1p36.11	uncertain significance
NM_024869.3(FAM110D):c.547C>G (p.Arg183Gly)	single nucleotide variant	not specified [RCV004110626]	Chr1:26161838 [GRCh38] Chr1:26488329 [GRCh37] Chr1:1p36.11	uncertain significance
NM_024869.3(FAM110D):c.725C>G (p.Pro242Arg)	single nucleotide variant	not specified [RCV004165062]	Chr1:26162016 [GRCh38] Chr1:26488507 [GRCh37] Chr1:1p36.11	uncertain significance
NM_024869.3(FAM110D):c.616G>C (p.Gly206Arg)	single nucleotide variant	not specified [RCV004267207]	Chr1:26161907 [GRCh38] Chr1:26488398 [GRCh37] Chr1:1p36.11	uncertain significance
NM_024869.3(FAM110D):c.100G>C (p.Val34Leu)	single nucleotide variant	not specified [RCV004268697]	Chr1:26161391 [GRCh38] Chr1:26487882 [GRCh37] Chr1:1p36.11	uncertain significance
NM_024869.3(FAM110D):c.272G>A (p.Arg91Gln)	single nucleotide variant	not specified [RCV004273896]	Chr1:26161563 [GRCh38] Chr1:26488054 [GRCh37] Chr1:1p36.11	uncertain significance
NM_024869.3(FAM110D):c.737T>C (p.Val246Ala)	single nucleotide variant	not specified [RCV004267854]	Chr1:26162028 [GRCh38] Chr1:26488519 [GRCh37] Chr1:1p36.11	uncertain significance
NM_024869.3(FAM110D):c.590C>G (p.Ala197Gly)	single nucleotide variant	not specified [RCV004249844]	Chr1:26161881 [GRCh38] Chr1:26488372 [GRCh37] Chr1:1p36.11	uncertain significance
NM_024869.3(FAM110D):c.640A>C (p.Ser214Arg)	single nucleotide variant	not specified [RCV004348815]	Chr1:26161931 [GRCh38] Chr1:26488422 [GRCh37] Chr1:1p36.11	uncertain significance
NM_024869.3(FAM110D):c.35G>C (p.Gly12Ala)	single nucleotide variant	not specified [RCV004354053]	Chr1:26161326 [GRCh38] Chr1:26487817 [GRCh37] Chr1:1p36.11	uncertain significance
NM_024869.3(FAM110D):c.604C>G (p.Pro202Ala)	single nucleotide variant	not specified [RCV004360377]	Chr1:26161895 [GRCh38] Chr1:26488386 [GRCh37] Chr1:1p36.11	uncertain significance
GRCh38/hg38 1p36.33-35.1(chr1:99125-34026935)x3	copy number gain	Trisomy 12p [RCV003447845]	Chr1:99125..34026935 [GRCh38] Chr1:1p36.33-35.1	pathogenic
NM_024869.3(FAM110D):c.394G>T (p.Ala132Ser)	single nucleotide variant	not specified [RCV004378513]	Chr1:26161685 [GRCh38] Chr1:26488176 [GRCh37] Chr1:1p36.11	likely benign
NM_024869.3(FAM110D):c.427C>G (p.Pro143Ala)	single nucleotide variant	not specified [RCV004378514]	Chr1:26161718 [GRCh38] Chr1:26488209 [GRCh37] Chr1:1p36.11	uncertain significance
NM_024869.3(FAM110D):c.751C>T (p.Arg251Cys)	single nucleotide variant	not specified [RCV004378518]	Chr1:26162042 [GRCh38] Chr1:26488533 [GRCh37] Chr1:1p36.11	uncertain significance
NM_024869.3(FAM110D):c.698C>T (p.Ala233Val)	single nucleotide variant	not specified [RCV004378516]	Chr1:26161989 [GRCh38] Chr1:26488480 [GRCh37] Chr1:1p36.11	uncertain significance
NM_024869.3(FAM110D):c.718C>T (p.Arg240Cys)	single nucleotide variant	not specified [RCV004378517]	Chr1:26162009 [GRCh38] Chr1:26488500 [GRCh37] Chr1:1p36.11	uncertain significance

miRNA Target Status

Confirmed Target Of

miRNA Gene	Mature miRNA	Method Name	Result Type	Data Type	Support Type	PMID
MIR1915	hsa-miR-1915-5p	Mirtarbase	external_info	CLASH	Functional MTI (Weak)	23622248

Predicted Target Of

	Summary Value
Count of predictions:	334
Count of miRNA genes:	238
Interacting mature miRNAs:	241
Transcripts:	ENST00000374268
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

visual system

adipose tissue

appendage

entire extraembryonic component

pharyngeal arch

High

Medium

325

211

325

1050

235

370

208

488

808

489

Low

2005

1965

1139

384

535

222

3157

1910

3215

333

1120

954

164

396

2235

Below cutoff

677

243

226

695

230

108

135

102

122

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_024869	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AK024112	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK290715	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL391650	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AU119858	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC025658	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068277	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000374268 ⟹ ENSP00000363386

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	26,159,079 - 26,163,962 (+)	Ensembl

RefSeq Acc Id:

NM_024869 ⟹ NP_079145

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	26,159,079 - 26,163,962 (+)	NCBI
GRCh37	1	26,485,511 - 26,489,119 (+)	RGD
Build 36	1	26,358,098 - 26,361,706 (+)	NCBI Archive
Celera	1	24,882,208 - 24,885,816 (+)	RGD
HuRef	1	24,739,879 - 24,743,487 (+)	RGD
CHM1_1	1	26,598,737 - 26,602,345 (+)	NCBI
T2T-CHM13v2.0	1	25,996,509 - 26,001,393 (+)	NCBI

Sequence:

show sequence

AGTCTGGACCTGCCCAAGGACCCCTGCAATTAGGCCTCCCATGCAGAGGTCAGTGAGAGCCCAA
GCCAATTGCTCTAGGCCCCGTGGCTGGCTACTTATGGGGCACTGTCCTGACCAGCTCTGCTAAG
ATGCTCCTGGCCCCTCCCTCCACCCCGTCCAGAGGACGGACCCCCAGCGCCGTGGAGAGGCTGG
AAGCCGACAAAGCCAAGTATGTCAAGACGCACCAGGTGATAGCTAGGCGACAGGAGCCAGCCCT
GCGTGGGAGTCCTGGGCCGCTCACGCCGCACCCCTGCAACGAGCTGGGGCCCCCTGCATCGCCC
AGGACGCCCAGGCCGGTCCGCCGGGGAAGCGGCAGGCGGCTGCCGAGGCCTGATTCCCTCATCT
TCTACCGCCAGAAGCGGGACTGCAAGGCTTCGGTGAACAAAGAGAACGCCAAGGGCCAGGGTCT
GGTGCGGCGCCTCTTTCTGGGTGCCCCGCGGGACGCTGCCCCGAGCAGCCCGGCCTCCACAGAG
CGACCTGCGGCTTCAGGGGGTTGGGCTGCGCCCCAGGATGCCCCGGAAGCGGCGGGAAAGCGGG
CGCTGTGTCCCACGTGCTCGCTGCCCCTGTCGGAGAAGGAGCGCTTCTTCAACTACTGCGGCCT
GGAGCGCGCGCTGGTGGAGGTGCTGGGCGCAGAGCGCTTCTCCCCGCAGAGCTGGGGAGCCGAC
GCCAGCCCGCAGGCCGGAACTTCGCCGCCGCCCGGCTCCGGGGACGCCAGCGACTGGACATCCA
GCGACAGGGGCGTGGACAGCCCGGGCGGCGCGGGCGGCGGCGGCGGCTCGGAGGCAGCGGGCTC
GGCGCGGGACCGGCGCCCCCCGGTGTCGGTGGTGGAGCGCAACGCGCGCGTCATCCAGTGGCTG
TACGGCTGCCAGCGCGCCCGCGGACCGCCGCGCGAGTCCGAGGTGTGACCGCCGCGGCTCCGGA
CTGGCCCCGGGACTGGCCCCGGGCACGGAAAAGGACACCCCTCTTCTGGCGCGCTGGGTGCCTT
TGCGTAAGCCCTTCCTTCTGGAACTCAGTTTCGCGTCTGAACCTTGGGGAGGTGGAACAAGTTG
CTGCCGAAGGCCCTTCCCTGCTCCCGCGGCGAAGGGGGAGGGAGAGGCCTCTTGGTCCCTGTGG
AGACCCGGTCTGGGGAGTCACGATTGGGGTGGGAGATGAGCAAACCTGCTGAATAAAGTTAAAA
CGTTATTTAAATGGGGAGCTGAGGAAGGAGCAAACGGGTTTTCGCGGTTAAACCCGTGGGTTTT
GGAATGTGTGTTCCCGGCTGTGTGATCCTGGGCAAGAACTTGACCTCCCTGGACGCAGCGGCAC
CCCTCGGTTATTAAGGAGGGAGGAGTAGGGGATAGAAGTATTTCAAAATAGTTGTAATGCGCAT
GGCAAAGTGCCCAGCATATAGAAAGTGCTCAATAAACGATAACTGCTGTGACTTCTACCGAATG
AGTACTAACACTGTTGTGATCTCCACTGGCCTCCAGGTCGATCCAAACTAGAGCTGGGAGCTGG
GAATAATGCGCTTTGGGAGCCCGAGGAGGCGTCTGCTCCAGAAATCTGGGCTCCACCAGATCCT
AAAAGGCCCCATTCCCGGAGTTTTGCTGCCCCAGTTGTGGTCACTGGGTATGAAGGGCTGAGAT
CCAACCTTTCGGACACAAAAAGAAGGGAACCGGGCCGGGCGCGGTGGCTCAGGCCTGTAATCCC
AGCACTTTGGGAGGCTGAGGAGGGTAGATCACGAGATCAGGAGTTCGAGACCAGCCTGGCCAAC
ATGGGCTCTACTAAAAATACAAAAATTAGCTGAGCTTGGAGGCGCGCGCCTGTAATCCCAGCTA
CTCGGGAGGCTGAGGCAGGAGAATCGCTTGAATCCCAGAGGCGGAGGTTGCAGTGAGCCGAGAT
CGAGCCATTGCACTCCAGCCTGGGCAACAGGGCCAGACTCCGTCTCAAAAAATAAAAATAAAAA
TAAAAAAAGAAAAGAAGGAAACCTTTCCTGCCAGCCGGCAGGCTCCTGCCACTGCCTCCCTTTC
CTGCAAGGACACACAAGTTCGCCTATTTTCATCACAGGTTCGCACCTCCAAGCCTGCATCCTTC
ATGCACCTCCTTCCTTTGCCTGGGTTGCCGTTCCTTTTCTCTCTGCTCTTCCTTCTCTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTG
GCGGGATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTC
CCAAGTAGCTGGGACTACAGGCGCCCGCCACTACGCCCGGCTAATTTTTTGTATTTTTAGTAGA
GACGGGGTTTCACCGTTTTAGCCGGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTC
GGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCCCCTTCTTCCTTCTCG
GAGATAACGTATATTCTCCTCCAGGAAGCCGTCCTGAATGCCCCCAGTCAGCCTCACCTGCTCT
GAGCTCCCAAGTACAGTCCTATTTTTGGGCCTCAATTTGTCACCTTTTGTGGGACCCGCTGGTA
CTCTGGGTTCTCTAGTTAATCTTTGACCTTTTTCCTAGTACAGGGACGGCGCACATAGTAGGGC
CACAGGCACAGTTTGTTGAATTAAATGAGGCTGGAGAGGGCGATGGACGCAGTCCTCTGGAGCT
CTCCAACTTCCTGGAAAGTTGTACCTTAAATAAAAAACCCATCCTGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_079145	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH25658	(Get FASTA)	NCBI Sequence Viewer
	BAB14829	(Get FASTA)	NCBI Sequence Viewer
	BAF83404	(Get FASTA)	NCBI Sequence Viewer
	EAX07844	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000363386
	ENSP00000363386.3
GenBank Protein	Q8TAY7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_079145 ⟸ NM_024869

- UniProtKB:

A8K3V0 (UniProtKB/Swiss-Prot), Q9H7Z4 (UniProtKB/Swiss-Prot), Q8TAY7 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MLLAPPSTPSRGRTPSAVERLEADKAKYVKTHQVIARRQEPALRGSPGPLTPHPCNELGPPASP
RTPRPVRRGSGRRLPRPDSLIFYRQKRDCKASVNKENAKGQGLVRRLFLGAPRDAAPSSPASTE
RPAASGGWAAPQDAPEAAGKRALCPTCSLPLSEKERFFNYCGLERALVEVLGAERFSPQSWGAD
ASPQAGTSPPPGSGDASDWTSSDRGVDSPGGAGGGGGSEAAGSARDRRPPVSVVERNARVIQWL
YGCQRARGPPRESEV

hide sequence

RefSeq Acc Id:

ENSP00000363386 ⟸ ENST00000374268

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8TAY7-F1-model_v2	AlphaFold	Q8TAY7	1-271	view protein structure

Promoters

RGD ID:

6854608

Promoter ID:

EPDNEW_H469

Type:

initiation region

Name:

FAM110D_1

Description:

family with sequence similarity 110 member D

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	26,159,079 - 26,159,139	EPDNEW

RGD ID:

6785710

Promoter ID:

HG_KWN:1470

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

K562

Transcripts:

UC009VSC.1

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	1	26,360,731 - 26,361,231 (+)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:25860	AgrOrtholog
COSMIC	FAM110D	COSMIC
Ensembl Genes	ENSG00000197245	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000374268	ENTREZGENE
	ENST00000374268.5	UniProtKB/Swiss-Prot
GTEx	ENSG00000197245	GTEx
HGNC ID	HGNC:25860	ENTREZGENE
Human Proteome Map	FAM110D	Human Proteome Map
InterPro	FAM110	UniProtKB/Swiss-Prot
	FAM110_C	UniProtKB/Swiss-Prot
	FAM110_N	UniProtKB/Swiss-Prot
KEGG Report	hsa:79927	UniProtKB/Swiss-Prot
NCBI Gene	79927	ENTREZGENE
PANTHER	PROTEIN FAM110D	UniProtKB/Swiss-Prot
	PTHR14758	UniProtKB/Swiss-Prot
Pfam	FAM110_C	UniProtKB/Swiss-Prot
	FAM110_N	UniProtKB/Swiss-Prot
PharmGKB	PA142671706	PharmGKB
UniProt	A8K3V0	ENTREZGENE
	F110D_HUMAN	UniProtKB/Swiss-Prot, ENTREZGENE
	Q9H7Z4	ENTREZGENE
UniProt Secondary	A8K3V0	UniProtKB/Swiss-Prot
	Q9H7Z4	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-11-24	FAM110D	family with sequence similarity 110 member D		family with sequence similarity 110, member D	Symbol and/or name change	5135510	APPROVED
2011-12-06	FAM110D	family with sequence similarity 110, member D	GRRP1	glycine/arginine rich protein 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar