ZNF362 (zinc finger protein 362) - Rat Genome Database

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Gene: ZNF362 (zinc finger protein 362) Homo sapiens
Analyze
Symbol: ZNF362
Name: zinc finger protein 362
RGD ID: 1602182
HGNC Page HGNC:18079
Description: Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FLJ25476; lin-29; MGC138318; RN; rotund homolog
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38133,127,522 - 33,300,719 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl133,256,492 - 33,300,719 (+)EnsemblGRCh38hg38GRCh38
GRCh37133,722,093 - 33,766,320 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36133,494,761 - 33,538,907 (+)NCBINCBI36Build 36hg18NCBI36
Celera132,007,735 - 32,037,981 (+)NCBICelera
Cytogenetic Map1p35.1NCBI
HuRef131,852,429 - 31,882,672 (+)NCBIHuRef
CHM1_1133,837,666 - 33,881,773 (+)NCBICHM1_1
T2T-CHM13v2.0132,987,140 - 33,162,335 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10737800   PMID:12477932   PMID:19322201   PMID:21873635   PMID:25281560   PMID:27880917   PMID:28611215   PMID:28712289   PMID:28794006   PMID:29180619   PMID:29395067   PMID:29844126  
PMID:30554943   PMID:30585729   PMID:30804394   PMID:31091453   PMID:31586073   PMID:31753913   PMID:32203420   PMID:32891193   PMID:33640491   PMID:33961781   PMID:34079125   PMID:34189442  
PMID:34597346   PMID:35013218   PMID:36089195   PMID:36373674   PMID:36424410   PMID:36543142   PMID:37689310  


Genomics

Comparative Map Data
ZNF362
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38133,127,522 - 33,300,719 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl133,256,492 - 33,300,719 (+)EnsemblGRCh38hg38GRCh38
GRCh37133,722,093 - 33,766,320 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36133,494,761 - 33,538,907 (+)NCBINCBI36Build 36hg18NCBI36
Celera132,007,735 - 32,037,981 (+)NCBICelera
Cytogenetic Map1p35.1NCBI
HuRef131,852,429 - 31,882,672 (+)NCBIHuRef
CHM1_1133,837,666 - 33,881,773 (+)NCBICHM1_1
T2T-CHM13v2.0132,987,140 - 33,162,335 (+)NCBIT2T-CHM13v2.0
Zfp362
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394128,666,881 - 128,700,118 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4128,666,881 - 128,699,838 (-)EnsemblGRCm39 Ensembl
GRCm384128,773,085 - 128,806,112 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4128,773,088 - 128,806,045 (-)EnsemblGRCm38mm10GRCm38
MGSCv374128,450,329 - 128,483,356 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364128,275,389 - 128,308,416 (-)NCBIMGSCv36mm8
Celera4127,111,767 - 127,144,880 (-)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map462.25NCBI
Zfp362
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85146,403,469 - 146,437,707 (-)NCBIGRCr8
mRatBN7.25141,119,073 - 141,153,304 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5141,119,898 - 141,156,716 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5143,815,734 - 143,837,877 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05145,585,563 - 145,607,703 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05145,586,344 - 145,608,239 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05146,951,195 - 146,985,450 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5146,952,653 - 146,973,932 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05150,688,705 - 150,722,873 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45148,000,281 - 148,022,124 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15148,009,499 - 148,032,636 (-)NCBI
Celera5139,604,031 - 139,625,856 (-)NCBICelera
Cytogenetic Map5q36NCBI
Znf362
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545211,450,057 - 11,472,940 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545211,449,950 - 11,472,777 (+)NCBIChiLan1.0ChiLan1.0
ZNF362
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21193,526,113 - 193,704,825 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11192,648,304 - 192,827,005 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0132,412,726 - 32,586,712 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1133,740,196 - 33,772,024 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl133,741,628 - 33,770,353 (+)Ensemblpanpan1.1panPan2
ZNF362
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1268,142,574 - 68,182,938 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl268,142,342 - 68,168,440 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha264,720,734 - 64,761,050 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0268,704,668 - 68,744,994 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl268,704,668 - 68,744,942 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1265,517,366 - 65,557,724 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0266,539,932 - 66,580,230 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0267,531,981 - 67,572,304 (-)NCBIUU_Cfam_GSD_1.0
Znf362
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505850,281,656 - 50,306,534 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647416,107,640 - 16,133,004 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647416,106,820 - 16,131,889 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF362
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl689,513,851 - 89,554,930 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1689,513,826 - 89,555,149 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2683,543,198 - 83,565,916 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF362
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12099,579,814 - 99,607,528 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2099,579,622 - 99,601,860 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603317,071,703 - 17,113,728 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf362
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476416,307,980 - 16,335,875 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476416,295,631 - 16,336,100 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ZNF362
33 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1p35.2-35.1(chr1:30766758-33359428)x1 copy number loss See cases [RCV000053802] Chr1:30766758..33359428 [GRCh38]
Chr1:31239605..33825029 [GRCh37]
Chr1:31012192..33597616 [NCBI36]
Chr1:1p35.2-35.1		 pathogenic
GRCh38/hg38 1p36.11-34.2(chr1:24381206-41401517)x3 copy number gain See cases [RCV000138891] Chr1:24381206..41401517 [GRCh38]
Chr1:24707696..41886350 [GRCh37]
Chr1:24580283..41658937 [NCBI36]
Chr1:1p36.11-34.2		 pathogenic
GRCh37/hg19 1p36.12-12(chr1:20608823-120546301)x3 copy number loss not provided [RCV000762767] Chr1:20608823..120546301 [GRCh37]
Chr1:1p36.12-12		 likely benign
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
NM_152493.3(ZNF362):c.237C>G (p.Ser79Arg) single nucleotide variant not specified [RCV004304713] Chr1:33276482 [GRCh38]
Chr1:33742083 [GRCh37]
Chr1:1p35.1		 uncertain significance
NC_000001.10:g.(?_33241563)_(46663513_?)dup duplication Charcot-Marie-Tooth disease dominant intermediate C [RCV000708276] Chr1:33241563..46663513 [GRCh37]
Chr1:1p35.1-34.1		 uncertain significance
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p35.2-34.3(chr1:31562164-37421958)x3 copy number gain not provided [RCV000748949] Chr1:31562164..37421958 [GRCh37]
Chr1:1p35.2-34.3		 pathogenic
GRCh37/hg19 1p36.22-21.1(chr1:103343285-103455144)x3 copy number gain Global developmental delay [RCV000787285] Chr1:103343285..103455144 [GRCh37]
Chr1:1p36.22-21.1		 uncertain significance
NM_018207.3(TRIM62):c.1105C>A (p.His369Asn) single nucleotide variant not specified [RCV004283843] Chr1:33147500 [GRCh38]
Chr1:33613101 [GRCh37]
Chr1:1p35.1		 uncertain significance
GRCh37/hg19 1p35.2-35.1(chr1:30819875-34380419)x3 copy number gain not provided [RCV001005079] Chr1:30819875..34380419 [GRCh37]
Chr1:1p35.2-35.1		 likely pathogenic
NC_000001.10:g.(?_33241563)_(46663513_?)dup duplication Charcot-Marie-Tooth disease, dominant intermediate C [RCV001308684] Chr1:33241563..46663513 [GRCh37]
Chr1:1p35.1-34.1		 uncertain significance
GRCh37/hg19 1p35.1-33(chr1:33285582-47891811) copy number gain not specified [RCV002052781] Chr1:33285582..47891811 [GRCh37]
Chr1:1p35.1-33		 pathogenic
NM_018207.3(TRIM62):c.702G>A (p.Glu234=) single nucleotide variant not provided [RCV000962924] Chr1:33159747 [GRCh38]
Chr1:33625348 [GRCh37]
Chr1:1p35.1		 benign
NM_018207.3(TRIM62):c.621G>A (p.Thr207=) single nucleotide variant not provided [RCV000923212] Chr1:33159828 [GRCh38]
Chr1:33625429 [GRCh37]
Chr1:1p35.1		 likely benign
NM_018207.3(TRIM62):c.633C>T (p.Ile211=) single nucleotide variant not provided [RCV000901507] Chr1:33159816 [GRCh38]
Chr1:33625417 [GRCh37]
Chr1:1p35.1		 likely benign
NM_018207.3(TRIM62):c.1417G>A (p.Val473Ile) single nucleotide variant not provided [RCV000955697] Chr1:33147188 [GRCh38]
Chr1:33612789 [GRCh37]
Chr1:1p35.1		 benign
NM_018207.3(TRIM62):c.523C>A (p.Arg175=) single nucleotide variant not provided [RCV000917532] Chr1:33159926 [GRCh38]
Chr1:33625527 [GRCh37]
Chr1:1p35.1		 likely benign
NM_018207.3(TRIM62):c.1002C>T (p.Phe334=) single nucleotide variant not provided [RCV000901506] Chr1:33147603 [GRCh38]
Chr1:33613204 [GRCh37]
Chr1:1p35.1		 likely benign
NM_018207.3(TRIM62):c.616C>T (p.Arg206Cys) single nucleotide variant not specified [RCV004290969] Chr1:33159833 [GRCh38]
Chr1:33625434 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.752T>C (p.Leu251Pro) single nucleotide variant not specified [RCV004112621] Chr1:33159697 [GRCh38]
Chr1:33625298 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_152493.3(ZNF362):c.1234G>C (p.Gly412Arg) single nucleotide variant not specified [RCV004215114] Chr1:33299017 [GRCh38]
Chr1:33764618 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.349C>T (p.Pro117Ser) single nucleotide variant not specified [RCV004139651] Chr1:33181084 [GRCh38]
Chr1:33646685 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.135G>C (p.Gln45His) single nucleotide variant not specified [RCV004220448] Chr1:33181298 [GRCh38]
Chr1:33646899 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_152493.3(ZNF362):c.1255C>T (p.Leu419Phe) single nucleotide variant not specified [RCV004121669] Chr1:33299038 [GRCh38]
Chr1:33764639 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.718G>A (p.Asp240Asn) single nucleotide variant not specified [RCV004184182] Chr1:33159731 [GRCh38]
Chr1:33625332 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_152493.3(ZNF362):c.244G>A (p.Val82Ile) single nucleotide variant not specified [RCV004083356] Chr1:33276489 [GRCh38]
Chr1:33742090 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_152493.3(ZNF362):c.191C>T (p.Ser64Leu) single nucleotide variant not specified [RCV004111840] Chr1:33276436 [GRCh38]
Chr1:33742037 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.1003G>A (p.Asp335Asn) single nucleotide variant not specified [RCV004203748] Chr1:33147602 [GRCh38]
Chr1:33613203 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_152493.3(ZNF362):c.226G>A (p.Ala76Thr) single nucleotide variant not specified [RCV004148062] Chr1:33276471 [GRCh38]
Chr1:33742072 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_152493.3(ZNF362):c.431C>T (p.Thr144Ile) single nucleotide variant not specified [RCV004115970] Chr1:33280205 [GRCh38]
Chr1:33745806 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.467C>T (p.Ala156Val) single nucleotide variant not specified [RCV004110922] Chr1:33165508 [GRCh38]
Chr1:33631109 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.161G>C (p.Arg54Pro) single nucleotide variant not specified [RCV004306378] Chr1:33181272 [GRCh38]
Chr1:33646873 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.482A>G (p.Lys161Arg) single nucleotide variant not specified [RCV004335571] Chr1:33165493 [GRCh38]
Chr1:33631094 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.902C>T (p.Pro301Leu) single nucleotide variant not specified [RCV004339783] Chr1:33147703 [GRCh38]
Chr1:33613304 [GRCh37]
Chr1:1p35.1		 uncertain significance
Single allele inversion Bilateral polymicrogyria [RCV003459046] Chr1:33246132..61045156 [GRCh38]
Chr1:1p35.1-31.3		 likely pathogenic
GRCh38/hg38 1p36.33-35.1(chr1:99125-34026935)x3 copy number gain Trisomy 12p [RCV003447845] Chr1:99125..34026935 [GRCh38]
Chr1:1p36.33-35.1		 pathogenic
NM_152493.3(ZNF362):c.1233C>T (p.Pro411=) single nucleotide variant not provided [RCV003406294] Chr1:33299016 [GRCh38]
Chr1:33764617 [GRCh37]
Chr1:1p35.1		 likely benign
NM_018207.3(TRIM62):c.408+4599G>A single nucleotide variant not provided [RCV003406293] Chr1:33176426 [GRCh38]
Chr1:33642027 [GRCh37]
Chr1:1p35.1		 likely benign
NM_152493.3(ZNF362):c.799G>A (p.Ala267Thr) single nucleotide variant not specified [RCV004486719] Chr1:33281702 [GRCh38]
Chr1:33747303 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_152493.3(ZNF362):c.1223C>T (p.Thr408Met) single nucleotide variant not specified [RCV004486718] Chr1:33299006 [GRCh38]
Chr1:33764607 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.1400C>T (p.Pro467Leu) single nucleotide variant not specified [RCV004476043] Chr1:33147205 [GRCh38]
Chr1:33612806 [GRCh37]
Chr1:1p35.1		 uncertain significance
GRCh37/hg19 1p35.1-34.3(chr1:32859415-36454915) copy number loss not provided [RCV000767772] Chr1:32859415..36454915 [GRCh37]
Chr1:1p35.1-34.3		 pathogenic
NM_018207.3(TRIM62):c.575G>A (p.Arg192His) single nucleotide variant not specified [RCV004110238] Chr1:33159874 [GRCh38]
Chr1:33625475 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_152493.3(ZNF362):c.611G>T (p.Gly204Val) single nucleotide variant not specified [RCV004256030] Chr1:33280385 [GRCh38]
Chr1:33745986 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.1421G>A (p.Arg474His) single nucleotide variant not specified [RCV004323983] Chr1:33147184 [GRCh38]
Chr1:33612785 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_152493.3(ZNF362):c.605C>T (p.Pro202Leu) single nucleotide variant not specified [RCV004334376] Chr1:33280379 [GRCh38]
Chr1:33745980 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_152493.3(ZNF362):c.185C>T (p.Ser62Leu) single nucleotide variant not specified [RCV004360790] Chr1:33276430 [GRCh38]
Chr1:33742031 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.595G>A (p.Glu199Lys) single nucleotide variant not specified [RCV004476047] Chr1:33159854 [GRCh38]
Chr1:33625455 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.617G>A (p.Arg206His) single nucleotide variant not specified [RCV004476048] Chr1:33159832 [GRCh38]
Chr1:33625433 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.1274G>T (p.Gly425Val) single nucleotide variant not specified [RCV004476041] Chr1:33147331 [GRCh38]
Chr1:33612932 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.1289A>G (p.Tyr430Cys) single nucleotide variant not specified [RCV004476042] Chr1:33147316 [GRCh38]
Chr1:33612917 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.329T>C (p.Leu110Pro) single nucleotide variant not specified [RCV004476045] Chr1:33181104 [GRCh38]
Chr1:33646705 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.356T>C (p.Leu119Pro) single nucleotide variant not specified [RCV004476046] Chr1:33181077 [GRCh38]
Chr1:33646678 [GRCh37]
Chr1:1p35.1		 uncertain significance
NM_018207.3(TRIM62):c.68G>A (p.Ser23Asn) single nucleotide variant not specified [RCV004476049] Chr1:33181365 [GRCh38]
Chr1:33646966 [GRCh37]
Chr1:1p35.1		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3150
Count of miRNA genes:925
Interacting mature miRNAs:1150
Transcripts:ENST00000373428, ENST00000477934, ENST00000483388, ENST00000490959, ENST00000539719
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
G21909  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37133,766,173 - 33,766,297UniSTSGRCh37
Build 36133,538,760 - 33,538,884RGDNCBI36
Celera132,037,834 - 32,037,958RGD
Cytogenetic Map1p35.1UniSTS
HuRef131,882,525 - 31,882,649UniSTS
SHGC-30968  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37133,764,983 - 33,765,132UniSTSGRCh37
Build 36133,537,570 - 33,537,719RGDNCBI36
Celera132,036,644 - 32,036,793RGD
Cytogenetic Map1p35.1UniSTS
HuRef131,881,335 - 31,881,484UniSTS
TNG Radiation Hybrid Map115835.0UniSTS
GeneMap99-GB4 RH Map1111.15UniSTS
Whitehead-RH Map1129.5UniSTS
NCBI RH Map1251.9UniSTS
SGC34497  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37133,750,368 - 33,750,492UniSTSGRCh37
Build 36133,522,955 - 33,523,079RGDNCBI36
Celera132,022,020 - 32,022,144RGD
Cytogenetic Map1p35.1UniSTS
HuRef131,866,714 - 31,866,838UniSTS
GeneMap99-GB4 RH Map1110.26UniSTS
Whitehead-RH Map1112.4UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2136 2129 1295 226 939 69 4035 1701 3320 275 1401 1529 169 1173 2477 3
Low 302 858 430 397 999 395 322 496 412 144 59 84 5 1 31 311 3 2
Below cutoff 4 1 1 11 1 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001370212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_152493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005270507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005270508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047447107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047447108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047447109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047447110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054334630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054334631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054334632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054334633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054334634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054334635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF318356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK098342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL020995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL513327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW204855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC065039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC071632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC103704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC104779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC112113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF743001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX283663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT584103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000373428   ⟹   ENSP00000362527
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl133,270,575 - 33,300,719 (+)Ensembl
RefSeq Acc Id: ENST00000477934
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl133,280,350 - 33,281,973 (+)Ensembl
RefSeq Acc Id: ENST00000483388   ⟹   ENSP00000438354
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl133,256,545 - 33,280,414 (+)Ensembl
RefSeq Acc Id: ENST00000490959
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl133,256,619 - 33,275,248 (+)Ensembl
RefSeq Acc Id: ENST00000539719   ⟹   ENSP00000446335
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl133,256,492 - 33,300,719 (+)Ensembl
RefSeq Acc Id: NM_001370212   ⟹   NP_001357141
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38133,269,693 - 33,300,719 (+)NCBI
T2T-CHM13v2.0133,131,291 - 33,162,335 (+)NCBI
Sequence:
RefSeq Acc Id: NM_152493   ⟹   NP_689706
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38133,256,492 - 33,300,719 (+)NCBI
GRCh37133,721,908 - 33,766,321 (+)NCBI
Build 36133,494,761 - 33,538,907 (+)NCBI Archive
Celera132,007,735 - 32,037,981 (+)RGD
HuRef131,852,429 - 31,882,672 (+)ENTREZGENE
CHM1_1133,837,666 - 33,881,773 (+)NCBI
T2T-CHM13v2.0133,118,089 - 33,162,335 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005270507   ⟹   XP_005270564
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38133,256,492 - 33,300,719 (+)NCBI
GRCh37133,721,908 - 33,766,321 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005270508   ⟹   XP_005270565
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38133,269,693 - 33,300,719 (+)NCBI
GRCh37133,721,908 - 33,766,321 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047447107   ⟹   XP_047303063
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38133,238,579 - 33,300,719 (+)NCBI
RefSeq Acc Id: XM_047447108   ⟹   XP_047303064
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38133,127,522 - 33,300,719 (+)NCBI
RefSeq Acc Id: XM_047447109   ⟹   XP_047303065
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38133,256,865 - 33,300,719 (+)NCBI
RefSeq Acc Id: XM_047447110   ⟹   XP_047303066
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38133,256,492 - 33,300,719 (+)NCBI
RefSeq Acc Id: XM_054334630   ⟹   XP_054190605
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0133,100,155 - 33,162,335 (+)NCBI
RefSeq Acc Id: XM_054334631   ⟹   XP_054190606
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0132,987,140 - 33,162,335 (+)NCBI
RefSeq Acc Id: XM_054334632   ⟹   XP_054190607
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0133,118,465 - 33,162,335 (+)NCBI
RefSeq Acc Id: XM_054334633   ⟹   XP_054190608
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0133,118,089 - 33,162,335 (+)NCBI
RefSeq Acc Id: XM_054334634   ⟹   XP_054190609
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0133,131,291 - 33,162,335 (+)NCBI
RefSeq Acc Id: XM_054334635   ⟹   XP_054190610
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0133,118,089 - 33,162,335 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_689706   ⟸   NM_152493
- UniProtKB: Q8WYU4 (UniProtKB/Swiss-Prot),   Q5T0B9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005270564   ⟸   XM_005270507
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_005270565   ⟸   XM_005270508
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: NP_001357141   ⟸   NM_001370212
- UniProtKB: Q5T0B9 (UniProtKB/Swiss-Prot),   Q8WYU4 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSP00000362527   ⟸   ENST00000373428
RefSeq Acc Id: ENSP00000438354   ⟸   ENST00000483388
RefSeq Acc Id: ENSP00000446335   ⟸   ENST00000539719
RefSeq Acc Id: XP_047303064   ⟸   XM_047447108
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047303063   ⟸   XM_047447107
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047303066   ⟸   XM_047447110
- Peptide Label: isoform X4
RefSeq Acc Id: XP_047303065   ⟸   XM_047447109
- Peptide Label: isoform X2
- UniProtKB: Q5T0B9 (UniProtKB/Swiss-Prot),   Q8WYU4 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_054190606   ⟸   XM_054334631
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054190605   ⟸   XM_054334630
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054190610   ⟸   XM_054334635
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054190608   ⟸   XM_054334633
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054190607   ⟸   XM_054334632
- Peptide Label: isoform X2
- UniProtKB: Q5T0B9 (UniProtKB/Swiss-Prot),   Q8WYU4 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_054190609   ⟸   XM_054334634
- Peptide Label: isoform X3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5T0B9-F1-model_v2 AlphaFold Q5T0B9 1-420 view protein structure

Promoters
RGD ID:6854894
Promoter ID:EPDNEW_H612
Type:initiation region
Name:ZNF362_2
Description:zinc finger protein 362
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H613  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38133,238,587 - 33,238,647EPDNEW
RGD ID:6854896
Promoter ID:EPDNEW_H613
Type:initiation region
Name:ZNF362_1
Description:zinc finger protein 362
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H612  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38133,255,637 - 33,255,697EPDNEW
RGD ID:6787271
Promoter ID:HG_KWN:1886
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_152493,   OTTHUMT00000011858,   OTTHUMT00000011859
Position:
Human AssemblyChrPosition (strand)Source
Build 36133,493,776 - 33,495,207 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:18079 AgrOrtholog
COSMIC ZNF362 COSMIC
Ensembl Genes ENSG00000160094 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000373428 ENTREZGENE
  ENST00000373428.5 UniProtKB/Swiss-Prot
  ENST00000483388.5 UniProtKB/TrEMBL
  ENST00000539719 ENTREZGENE
  ENST00000539719.6 UniProtKB/Swiss-Prot
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot
GTEx ENSG00000160094 GTEx
HGNC ID HGNC:18079 ENTREZGENE
Human Proteome Map ZNF362 Human Proteome Map
InterPro Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report hsa:149076 UniProtKB/Swiss-Prot
NCBI Gene 149076 ENTREZGENE
PANTHER KRUEPPEL-LIKE FACTOR 15 UniProtKB/Swiss-Prot
  KRUEPPEL-LIKE TRANSCRIPTION FACTOR UniProtKB/Swiss-Prot
Pfam zf-C2H2 UniProtKB/Swiss-Prot
PharmGKB PA38290 PharmGKB
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
SMART ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot
UniProt F5H055_HUMAN UniProtKB/TrEMBL
  Q5T0B9 ENTREZGENE
  Q8WYU4 ENTREZGENE
  ZN362_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary Q8WYU4 UniProtKB/Swiss-Prot