EIF1AD (eukaryotic translation initiation factor 1A domain containing) - Rat Genome Database

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Gene: EIF1AD (eukaryotic translation initiation factor 1A domain containing) Homo sapiens
Analyze
Symbol: EIF1AD
Name: eukaryotic translation initiation factor 1A domain containing
RGD ID: 1601944
HGNC Page HGNC:28147
Description: Predicted to enable RNA binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Located in cytosol and nucleoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: eukaryotic translation initiation factor 1A domain-containing protein; haponin; hypothetical protein mgc11102; MGC11102; OBELIX; probable RNA-binding protein EIF1AD
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,996,545 - 66,002,157 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,996,545 - 66,002,176 (-)EnsemblGRCh38hg38GRCh38
GRCh371165,764,016 - 65,769,628 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361165,520,593 - 65,526,154 (-)NCBINCBI36Build 36hg18NCBI36
Celera1163,088,432 - 63,093,993 (-)NCBICelera
Cytogenetic Map11q13.1NCBI
HuRef1162,090,111 - 62,095,733 (-)NCBIHuRef
CHM1_11165,648,146 - 65,653,767 (-)NCBICHM1_1
T2T-CHM13v2.01165,990,678 - 65,996,291 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14702039   PMID:15342556   PMID:16189514   PMID:16344560   PMID:16751776   PMID:17207965   PMID:18173130   PMID:19322201   PMID:21516116   PMID:21873635   PMID:22095125  
PMID:22658674   PMID:24927181   PMID:24981860   PMID:25416956   PMID:28514442   PMID:28700943   PMID:30180896   PMID:31515488   PMID:32296183   PMID:32640226   PMID:33226137   PMID:33961781  
PMID:34373451   PMID:35271311   PMID:35831314   PMID:35944360  


Genomics

Comparative Map Data
EIF1AD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,996,545 - 66,002,157 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,996,545 - 66,002,176 (-)EnsemblGRCh38hg38GRCh38
GRCh371165,764,016 - 65,769,628 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361165,520,593 - 65,526,154 (-)NCBINCBI36Build 36hg18NCBI36
Celera1163,088,432 - 63,093,993 (-)NCBICelera
Cytogenetic Map11q13.1NCBI
HuRef1162,090,111 - 62,095,733 (-)NCBIHuRef
CHM1_11165,648,146 - 65,653,767 (-)NCBICHM1_1
T2T-CHM13v2.01165,990,678 - 65,996,291 (-)NCBIT2T-CHM13v2.0
Eif1ad
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39195,416,841 - 5,421,546 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl195,416,769 - 5,421,554 (+)EnsemblGRCm39 Ensembl
GRCm38195,366,813 - 5,371,518 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl195,366,741 - 5,371,526 (+)EnsemblGRCm38mm10GRCm38
MGSCv37195,366,813 - 5,371,511 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36195,366,813 - 5,371,511 (+)NCBIMGSCv36mm8
Celera195,239,138 - 5,243,840 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.31NCBI
Eif1ad
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81212,103,715 - 212,109,015 (+)NCBIGRCr8
mRatBN7.21202,674,362 - 202,679,662 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1202,674,185 - 202,679,658 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1211,027,028 - 211,032,330 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,119,784 - 218,125,084 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01210,810,833 - 210,816,133 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01220,746,387 - 220,751,687 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1220,746,387 - 220,751,684 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01227,675,718 - 227,681,018 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41208,010,510 - 208,015,810 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11208,163,962 - 208,169,260 (+)NCBI
Celera1200,209,677 - 200,214,977 (+)NCBICelera
Cytogenetic Map1q43NCBI
Eif1ad
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542219,339,111 - 19,345,109 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542219,339,111 - 19,343,673 (+)NCBIChiLan1.0ChiLan1.0
EIF1AD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2967,208,036 - 67,234,776 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11168,254,659 - 68,277,622 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01161,356,142 - 61,366,589 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11164,689,797 - 64,693,534 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1164,689,797 - 64,693,534 (-)Ensemblpanpan1.1panPan2
EIF1AD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11851,271,850 - 51,276,215 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1851,272,855 - 51,274,487 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1849,879,845 - 49,884,759 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01852,309,334 - 52,314,262 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1852,309,802 - 52,313,211 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11851,409,562 - 51,412,782 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01850,983,848 - 50,988,764 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01851,773,608 - 51,778,523 (+)NCBIUU_Cfam_GSD_1.0
Eif1ad
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049477,112,840 - 7,116,094 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365993,555,273 - 3,562,842 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365993,555,273 - 3,558,443 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF1AD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl26,334,197 - 6,340,112 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.126,334,882 - 6,340,125 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.225,438,839 - 5,443,814 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EIF1AD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.118,255,904 - 8,259,278 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl18,255,378 - 8,259,104 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038105,540,590 - 105,544,081 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif1ad
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476720,437,053 - 20,439,796 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476720,436,929 - 20,439,796 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in EIF1AD
9 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3		 pathogenic
GRCh38/hg38 11q13.1-13.2(chr11:65741431-67705669)x1 copy number loss See cases [RCV000142881] Chr11:65741431..67705669 [GRCh38]
Chr11:65508902..67473140 [GRCh37]
Chr11:65265478..67229716 [NCBI36]
Chr11:11q13.1-13.2		 pathogenic
NM_001242481.2(EIF1AD):c.-322_-321dup duplication Nestor-Guillermo progeria syndrome [RCV000305201] Chr11:66002113..66002114 [GRCh38]
Chr11:65769584..65769585 [GRCh37]
Chr11:11q13.1		 uncertain significance
NM_001242481.2(EIF1AD):c.-329G>A single nucleotide variant Nestor-Guillermo progeria syndrome [RCV000357516] Chr11:66002122 [GRCh38]
Chr11:65769593 [GRCh37]
Chr11:11q13.1		 likely benign|uncertain significance
NM_001242481.2(EIF1AD):c.-316C>T single nucleotide variant Nestor-Guillermo progeria syndrome [RCV000266406] Chr11:66002109 [GRCh38]
Chr11:65769580 [GRCh37]
Chr11:11q13.1		 uncertain significance
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 copy number gain MISSED ABORTION [RCV002282973] Chr11:32799481..134938470 [GRCh37]
Chr11:11p13-q25		 pathogenic
NM_001242481.2(EIF1AD):c.-308C>G single nucleotide variant Nestor-Guillermo progeria syndrome [RCV000363414] Chr11:66002101 [GRCh38]
Chr11:65769572 [GRCh37]
Chr11:11q13.1		 uncertain significance
NM_001242481.2(EIF1AD):c.-297T>C single nucleotide variant Nestor-Guillermo progeria syndrome [RCV000306436] Chr11:66002090 [GRCh38]
Chr11:65769561 [GRCh37]
Chr11:11q13.1		 uncertain significance
GRCh37/hg19 11q13.1-13.2(chr11:64501919-67129258)x3 copy number gain See cases [RCV000511632] Chr11:64501919..67129258 [GRCh37]
Chr11:11q13.1-13.2		 likely pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
NM_001242481.2(EIF1AD):c.173G>A (p.Arg58His) single nucleotide variant not specified [RCV004327703] Chr11:66000076 [GRCh38]
Chr11:65767547 [GRCh37]
Chr11:11q13.1		 uncertain significance
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11q13.1-13.2(chr11:65138976-67574402) copy number gain not provided [RCV000767601] Chr11:65138976..67574402 [GRCh37]
Chr11:11q13.1-13.2		 pathogenic
NC_000011.9:g.(?_65633902)_(66115026_?)dup duplication Cutis laxa, autosomal recessive, type 1B [RCV000798155] Chr11:65866431..66347555 [GRCh38]
Chr11:65633902..66115026 [GRCh37]
Chr11:11q13.1-13.2		 uncertain significance
NC_000011.9:g.(?_64973914)_(70052579_?)dup duplication Aicardi-Goutieres syndrome 3 [RCV003113322]|FADD-related immunodeficiency [RCV003107753] Chr11:64973914..70052579 [GRCh37]
Chr11:11q13.1-13.3		 uncertain significance
NC_000011.9:g.(?_59596957)_(68707199_?)dup duplication Familial temporal lobe epilepsy 8 [RCV001372442] Chr11:59596957..68707199 [GRCh37]
Chr11:11q12.1-13.3		 uncertain significance
NC_000011.9:g.(?_65633902)_(66115026_?)dup duplication Autosomal recessive cutis laxa type 1B [RCV001305354] Chr11:65633902..66115026 [GRCh37]
Chr11:11q13.1-13.2		 uncertain significance
GRCh37/hg19 11q13.1-13.2(chr11:64935724-66405514) copy number loss not specified [RCV002052930] Chr11:64935724..66405514 [GRCh37]
Chr11:11q13.1-13.2		 uncertain significance
NC_000011.9:g.(?_64522783)_(66283694_?)del deletion Bardet-Biedl syndrome [RCV002014493]|Glycogen storage disease, type V [RCV002004587] Chr11:64522783..66283694 [GRCh37]
Chr11:11q13.1-13.2		 pathogenic
NM_001242481.2(EIF1AD):c.49G>A (p.Glu17Lys) single nucleotide variant not specified [RCV004151840] Chr11:66000341 [GRCh38]
Chr11:65767812 [GRCh37]
Chr11:11q13.1		 uncertain significance
GRCh37/hg19 11q12.2-13.5(chr11:59923608-76272324)x3 copy number gain not provided [RCV003484842] Chr11:59923608..76272324 [GRCh37]
Chr11:11q12.2-13.5		 pathogenic
GRCh37/hg19 11q12.1-13.3(chr11:56895955-69295402)x3 copy number gain not specified [RCV003986944] Chr11:56895955..69295402 [GRCh37]
Chr11:11q12.1-13.3		 likely pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3908
Count of miRNA genes:1006
Interacting mature miRNAs:1219
Transcripts:ENST00000312234, ENST00000525767, ENST00000526449, ENST00000526451, ENST00000527051, ENST00000527249, ENST00000529964, ENST00000529973, ENST00000530462, ENST00000532707, ENST00000533544
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH69702  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371165,771,349 - 65,771,493UniSTSGRCh37
GRCh372231,589,608 - 231,589,752UniSTSGRCh37
Build 362231,297,852 - 231,297,996RGDNCBI36
Celera1163,095,770 - 63,095,914UniSTS
Celera2225,366,043 - 225,366,187RGD
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map11q13.1UniSTS
HuRef1162,097,438 - 62,097,582UniSTS
HuRef2223,429,585 - 223,429,729UniSTS
RH93037  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371165,765,897 - 65,766,053UniSTSGRCh37
Build 361165,522,473 - 65,522,629RGDNCBI36
Celera1163,090,312 - 63,090,468RGD
Cytogenetic Map11q13.1UniSTS
HuRef1162,091,992 - 62,092,148UniSTS
GeneMap99-GB4 RH Map11247.67UniSTS
RH16528  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371165,764,167 - 65,764,287UniSTSGRCh37
Build 361165,520,743 - 65,520,863RGDNCBI36
Celera1163,088,582 - 63,088,702RGD
Cytogenetic Map11q13.1UniSTS
HuRef1162,090,262 - 62,090,382UniSTS
GeneMap99-GB4 RH Map11244.55UniSTS
NCBI RH Map11573.2UniSTS
WIAF-1719  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371165,764,133 - 65,764,273UniSTSGRCh37
Build 361165,520,709 - 65,520,849RGDNCBI36
Celera1163,088,548 - 63,088,688RGD
Cytogenetic Map11q13.1UniSTS
HuRef1162,090,228 - 62,090,368UniSTS
GeneMap99-GB4 RH Map11247.67UniSTS
NCBI RH Map11573.2UniSTS
GDB:335751  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1q42.12UniSTS
Cytogenetic Map9q34.13UniSTS
Cytogenetic Map9p13.3-p12UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map9q22.3UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map11q24.2UniSTS
Cytogenetic Map10q23.1UniSTS
Cytogenetic Map10q24.1UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map10q11.1UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map3q22.2UniSTS
Cytogenetic Map15q14UniSTS
Cytogenetic Map11q23.1UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map8q22UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map7p21.2UniSTS
Cytogenetic Map3p21-p12UniSTS
Cytogenetic Map3q26.2UniSTS
Cytogenetic Map9q21.32UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map10q26.3UniSTS
Cytogenetic Map18p11.31UniSTS
Cytogenetic Map17q24.1UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map13q11UniSTS
Cytogenetic Map10q11.22UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map6p21.1-p12.2UniSTS
Cytogenetic Map9p12UniSTS
Cytogenetic Map21q22.11UniSTS
Cytogenetic Map13q14.3UniSTS
Cytogenetic Map1q21.3UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map3q27.1UniSTS
Cytogenetic Map22q13UniSTS
Cytogenetic Map16q12.1UniSTS
Cytogenetic Map10q24.32UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map12q24UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map1p34.1UniSTS
Cytogenetic Map3q21UniSTS
Cytogenetic Map5q11.2UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map13q12.13UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map11q13.4UniSTS
Cytogenetic Map2q14.3UniSTS
Cytogenetic Map10q23.33UniSTS
Cytogenetic MapXq24UniSTS
Cytogenetic Map2q37.3UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map20q13.33UniSTS
Cytogenetic Map5p12UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map6q22.1UniSTS
Cytogenetic Map17p13UniSTS
Cytogenetic Map8p11UniSTS
Cytogenetic Map18q21.33UniSTS
Cytogenetic Map14q23.2UniSTS
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map10q26UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map3p14.3UniSTS
Cytogenetic Map22q13.1-q13.2UniSTS
Cytogenetic Map14q32UniSTS
Cytogenetic Map9q31.3UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map7q11.21UniSTS
Cytogenetic Map4q24UniSTS
Cytogenetic Map19q13.11UniSTS
Cytogenetic Map10p11.21UniSTS
Cytogenetic Map6p12.3UniSTS
Cytogenetic Map3q12.1UniSTS
Cytogenetic Map6q13UniSTS
Cytogenetic Map1q32.3UniSTS
Cytogenetic Map1q21.1UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map5p13UniSTS
Cytogenetic Map15q11.2UniSTS
Cytogenetic Map10q24-q25UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map21q22.2UniSTS
Cytogenetic Map11q13.5UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map6p24.1UniSTS
Cytogenetic Map9q22.32UniSTS
D1S1361  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16q11.2UniSTS
Cytogenetic Map12q24UniSTS
Cytogenetic Map20q13.32UniSTS
Cytogenetic Map12q13.2UniSTS
Cytogenetic Map9q32UniSTS
Cytogenetic Map1q44UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic MapXq21.1UniSTS
Cytogenetic Map2q21.1UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map1p35.3UniSTS
Cytogenetic Map8q24UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map22q11.2UniSTS
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map1p34UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map6p21.1-p12.1UniSTS
Cytogenetic Map1q21.3UniSTS
Cytogenetic Map1q42.12UniSTS
Cytogenetic Map16p13.12UniSTS
Cytogenetic Map4q22.1UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map5q21UniSTS
Cytogenetic Map3q25.33UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map1q25.3UniSTS
Cytogenetic Map19p13.13UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic Map10q24UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map5p13.1UniSTS
Cytogenetic MapXq24UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map5p13.3UniSTS
Cytogenetic Map5q22.2UniSTS
Cytogenetic Map1p31UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map20q13.2UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map6p21.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map5q33.1UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map7p22.3UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map21q22.2UniSTS
Cytogenetic Map17q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2068 1471 1354 309 1340 165 3813 1250 1678 301 1405 1551 160 1 1070 2300 4 2
Low 371 1518 372 315 609 300 544 947 2056 118 55 62 15 134 488 2
Below cutoff 2 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001242481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001242482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001242483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001242484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001242485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001242486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_032325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017018412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054370174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AI831454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK094129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK311891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP006287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW872373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE669813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE791453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG149615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP328412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU790195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS300548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA024526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ600634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000312234   ⟹   ENSP00000309175
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,996,545 - 66,002,157 (-)Ensembl
RefSeq Acc Id: ENST00000525767   ⟹   ENSP00000434796
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,998,389 - 66,002,161 (-)Ensembl
RefSeq Acc Id: ENST00000526449
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,999,898 - 66,002,157 (-)Ensembl
RefSeq Acc Id: ENST00000526451   ⟹   ENSP00000436644
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,996,545 - 66,002,156 (-)Ensembl
RefSeq Acc Id: ENST00000527051   ⟹   ENSP00000432135
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,999,637 - 66,000,742 (-)Ensembl
RefSeq Acc Id: ENST00000527249   ⟹   ENSP00000435439
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,998,567 - 66,002,176 (-)Ensembl
RefSeq Acc Id: ENST00000529964   ⟹   ENSP00000435942
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,998,433 - 66,002,166 (-)Ensembl
RefSeq Acc Id: ENST00000529973   ⟹   ENSP00000436876
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,998,614 - 66,000,482 (-)Ensembl
RefSeq Acc Id: ENST00000530462   ⟹   ENSP00000435891
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,999,360 - 66,002,160 (-)Ensembl
RefSeq Acc Id: ENST00000532707   ⟹   ENSP00000433320
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,999,363 - 66,002,136 (-)Ensembl
RefSeq Acc Id: ENST00000533544   ⟹   ENSP00000434056
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,996,545 - 66,002,157 (-)Ensembl
RefSeq Acc Id: NM_001242481   ⟹   NP_001229410
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,996,545 - 66,002,157 (-)NCBI
GRCh371165,764,016 - 65,769,637 (-)ENTREZGENE
HuRef1162,090,111 - 62,095,733 (-)ENTREZGENE
CHM1_11165,648,146 - 65,653,767 (-)NCBI
T2T-CHM13v2.01165,990,678 - 65,996,291 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001242482   ⟹   NP_001229411
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,996,545 - 66,002,157 (-)NCBI
GRCh371165,764,016 - 65,769,637 (-)ENTREZGENE
HuRef1162,090,111 - 62,095,733 (-)ENTREZGENE
CHM1_11165,648,146 - 65,653,767 (-)NCBI
T2T-CHM13v2.01165,990,678 - 65,996,291 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001242483   ⟹   NP_001229412
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,996,545 - 66,002,157 (-)NCBI
GRCh371165,764,016 - 65,769,637 (-)ENTREZGENE
HuRef1162,090,111 - 62,095,733 (-)ENTREZGENE
CHM1_11165,648,146 - 65,653,767 (-)NCBI
T2T-CHM13v2.01165,990,678 - 65,996,291 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001242484   ⟹   NP_001229413
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,996,545 - 66,002,157 (-)NCBI
GRCh371165,764,016 - 65,769,637 (-)ENTREZGENE
HuRef1162,090,111 - 62,095,733 (-)ENTREZGENE
CHM1_11165,648,146 - 65,653,767 (-)NCBI
T2T-CHM13v2.01165,990,678 - 65,996,291 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001242485   ⟹   NP_001229414
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,996,545 - 66,002,157 (-)NCBI
GRCh371165,764,016 - 65,769,637 (-)ENTREZGENE
HuRef1162,090,111 - 62,095,733 (-)ENTREZGENE
CHM1_11165,648,146 - 65,653,767 (-)NCBI
T2T-CHM13v2.01165,990,678 - 65,996,291 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001242486   ⟹   NP_001229415
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,996,545 - 66,002,157 (-)NCBI
GRCh371165,764,016 - 65,769,637 (-)ENTREZGENE
HuRef1162,090,111 - 62,095,733 (-)ENTREZGENE
CHM1_11165,648,146 - 65,653,767 (-)NCBI
T2T-CHM13v2.01165,990,678 - 65,996,291 (-)NCBI
Sequence:
RefSeq Acc Id: NM_032325   ⟹   NP_115701
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,996,545 - 66,002,157 (-)NCBI
GRCh371165,764,016 - 65,769,637 (-)ENTREZGENE
Build 361165,520,593 - 65,526,154 (-)NCBI Archive
Celera1163,088,432 - 63,093,993 (-)RGD
HuRef1162,090,111 - 62,095,733 (-)ENTREZGENE
CHM1_11165,648,146 - 65,653,767 (-)NCBI
T2T-CHM13v2.01165,990,678 - 65,996,291 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017018412   ⟹   XP_016873901
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,996,545 - 66,002,157 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054370174   ⟹   XP_054226149
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01165,990,678 - 65,996,264 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_115701   ⟸   NM_032325
- UniProtKB: B2R4N5 (UniProtKB/Swiss-Prot),   Q9BSC1 (UniProtKB/Swiss-Prot),   Q8N9N8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001229415   ⟸   NM_001242486
- UniProtKB: B2R4N5 (UniProtKB/Swiss-Prot),   Q9BSC1 (UniProtKB/Swiss-Prot),   Q8N9N8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001229414   ⟸   NM_001242485
- UniProtKB: B2R4N5 (UniProtKB/Swiss-Prot),   Q9BSC1 (UniProtKB/Swiss-Prot),   Q8N9N8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001229413   ⟸   NM_001242484
- UniProtKB: B2R4N5 (UniProtKB/Swiss-Prot),   Q9BSC1 (UniProtKB/Swiss-Prot),   Q8N9N8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001229412   ⟸   NM_001242483
- UniProtKB: B2R4N5 (UniProtKB/Swiss-Prot),   Q9BSC1 (UniProtKB/Swiss-Prot),   Q8N9N8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001229411   ⟸   NM_001242482
- UniProtKB: B2R4N5 (UniProtKB/Swiss-Prot),   Q9BSC1 (UniProtKB/Swiss-Prot),   Q8N9N8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001229410   ⟸   NM_001242481
- UniProtKB: B2R4N5 (UniProtKB/Swiss-Prot),   Q9BSC1 (UniProtKB/Swiss-Prot),   Q8N9N8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016873901   ⟸   XM_017018412
- Peptide Label: isoform X1
- UniProtKB: B2R4N5 (UniProtKB/Swiss-Prot),   Q9BSC1 (UniProtKB/Swiss-Prot),   Q8N9N8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000435891   ⟸   ENST00000530462
RefSeq Acc Id: ENSP00000433320   ⟸   ENST00000532707
RefSeq Acc Id: ENSP00000434056   ⟸   ENST00000533544
RefSeq Acc Id: ENSP00000309175   ⟸   ENST00000312234
RefSeq Acc Id: ENSP00000434796   ⟸   ENST00000525767
RefSeq Acc Id: ENSP00000436644   ⟸   ENST00000526451
RefSeq Acc Id: ENSP00000432135   ⟸   ENST00000527051
RefSeq Acc Id: ENSP00000435439   ⟸   ENST00000527249
RefSeq Acc Id: ENSP00000435942   ⟸   ENST00000529964
RefSeq Acc Id: ENSP00000436876   ⟸   ENST00000529973
RefSeq Acc Id: XP_054226149   ⟸   XM_054370174
- Peptide Label: isoform X1
- UniProtKB: Q8N9N8 (UniProtKB/Swiss-Prot),   B2R4N5 (UniProtKB/Swiss-Prot),   Q9BSC1 (UniProtKB/Swiss-Prot)
Protein Domains
S1-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8N9N8-F1-model_v2 AlphaFold Q8N9N8 1-165 view protein structure

Promoters
RGD ID:6788737
Promoter ID:HG_KWN:13375
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_032325,   UC001OGN.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361165,526,156 - 65,527,057 (-)MPROMDB
RGD ID:7221105
Promoter ID:EPDNEW_H16298
Type:initiation region
Name:EIF1AD_1
Description:eukaryotic translation initiation factor 1A domain containing
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H16300  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381166,002,156 - 66,002,216EPDNEW
RGD ID:7221109
Promoter ID:EPDNEW_H16300
Type:initiation region
Name:EIF1AD_2
Description:eukaryotic translation initiation factor 1A domain containing
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H16298  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381166,002,472 - 66,002,532EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:28147 AgrOrtholog
COSMIC EIF1AD COSMIC
Ensembl Genes ENSG00000175376 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000312234 ENTREZGENE
  ENST00000312234.6 UniProtKB/Swiss-Prot
  ENST00000525767.5 UniProtKB/TrEMBL
  ENST00000526451 ENTREZGENE
  ENST00000526451.5 UniProtKB/Swiss-Prot
  ENST00000527051.1 UniProtKB/TrEMBL
  ENST00000527249 ENTREZGENE
  ENST00000527249.5 UniProtKB/Swiss-Prot
  ENST00000529964 ENTREZGENE
  ENST00000529964.5 UniProtKB/Swiss-Prot
  ENST00000529973.1 UniProtKB/TrEMBL
  ENST00000530462.5 UniProtKB/TrEMBL
  ENST00000532707.5 UniProtKB/TrEMBL
  ENST00000533544 ENTREZGENE
  ENST00000533544.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.1200.180 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.40.50.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000175376 GTEx
HGNC ID HGNC:28147 ENTREZGENE
Human Proteome Map EIF1AD Human Proteome Map
InterPro EIF1AD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA-binding_domain_S1_IF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIF_eIF-1A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:84285 UniProtKB/Swiss-Prot
NCBI Gene 84285 ENTREZGENE
OMIM 618473 OMIM
PANTHER PTHR21641 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA-BINDING PROTEIN EIF1AD-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam eIF-1a UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA162384553 PharmGKB
PROSITE S1_IF1_TYPE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART eIF1a UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50249 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2R4N5 ENTREZGENE
  E9PLI6_HUMAN UniProtKB/TrEMBL
  E9PNH5_HUMAN UniProtKB/TrEMBL
  E9PQD0_HUMAN UniProtKB/TrEMBL
  E9PS30_HUMAN UniProtKB/TrEMBL
  E9PS76_HUMAN UniProtKB/TrEMBL
  EIF1A_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q9BSC1 ENTREZGENE
UniProt Secondary B2R4N5 UniProtKB/Swiss-Prot
  Q9BSC1 UniProtKB/Swiss-Prot