Eif6-ps1 (eukaryotic translation initiation factor 6, pseudogene 1) - Rat Genome Database

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Gene: Eif6-ps1 (eukaryotic translation initiation factor 6, pseudogene 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Eif6-ps1
Name: eukaryotic translation initiation factor 6, pseudogene 1
RGD ID: 1591457
Description: Predicted to enable ribosomal large subunit binding activity and translation initiation factor activity. Predicted to be involved in ribosome biogenesis and translational initiation. Predicted to be located in cytoplasm and nucleolus; INTERACTS WITH (+)-schisandrin B; tetrachloromethane.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: MODEL
Previously known as: LOC684355; similar to Eukaryotic translation initiation factor 6 (eIF-6) (B4 integrin interactor) (CAB) (p27(BBP)) (B(2)GCN homolog)
RGD Orthologs
Alliance Genes
More Info homologs ...
Related Functional Gene: Eif6  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81485,798,003 - 85,798,950 (-)NCBIGRCr8
mRatBN7.21481,584,117 - 81,585,052 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1481,584,160 - 81,584,897 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01486,979,277 - 86,980,041 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,979,280 - 86,980,017 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01480,612,041 - 80,612,850 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41487,465,006 - 87,465,743 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1480,465,219 - 80,465,983 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:15057822  


Genomics

Variants

.
Variants in Eif6-ps1
33 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)146875779683368335Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147341532392554092Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147341532392554092Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)147995092195876975Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system exocrine system hemolymphoid system hepatobiliary system renal system reproductive system respiratory system
High
Medium
Low
Below cutoff 7 2 3 2 1 6 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000083783
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1481,584,160 - 81,584,897 (-)Ensembl
Rnor_6.0 Ensembl1486,979,280 - 86,980,017 (-)Ensembl
RefSeq Acc Id: XR_594061
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1480,465,195 - 80,465,983 (-)NCBI
RefSeq Acc Id: XR_595899
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01486,979,253 - 86,980,041 (-)NCBI
Protein Sequences
Ensembl Protein ENSRNOP00000091697.1
Reference Protein Sequences

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-15055 BioCyc
Ensembl Genes ENSRNOG00000058513 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000083783.2 UniProtKB/TrEMBL
InterPro eIF6 UniProtKB/TrEMBL
NCBI Gene 684355 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 6 UniProtKB/TrEMBL
  PTHR10784 UniProtKB/TrEMBL
Pfam eIF-6 UniProtKB/TrEMBL
PhenoGen Eif6-ps1 PhenoGen
PIRSF IF-6 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000058513 RatGTEx
SMART eIF6 UniProtKB/TrEMBL
Superfamily-SCOP Pentein UniProtKB/TrEMBL
UniProt A0A8I6AC66_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-11 Eif6-ps1  eukaryotic translation initiation factor 6, pseudogene 1  LOC684355  similar to Eukaryotic translation initiation factor 6 (eIF-6) (B4 integrin interactor) (CAB) (p27(BBP)) (B(2)GCN homolog)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC684355  similar to Eukaryotic translation initiation factor 6 (eIF-6) (B4 integrin interactor) (CAB) (p27(BBP)) (B(2)GCN homolog)      Symbol and Name status set to provisional 70820 PROVISIONAL