Mospd1l1 (motile sperm domain containing 1 like 1) - Rat Genome Database

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Gene: Mospd1l1 (motile sperm domain containing 1 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Mospd1l1 (Ensembl: LOC686087)
Name: motile sperm domain containing 1 like 1 (Ensembl:similar to motile sperm domain containing 1)
RGD ID: 1586609
Description: Predicted to be located in Golgi membrane and endoplasmic reticulum membrane. Orthologous to human MOSPD1 (motile sperm domain containing 1).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC686087; motile sperm domain-containing protein 1; similar to motile sperm domain containing 1
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81486,501,415 - 86,503,257 (-)NCBIGRCr8
mRatBN7.21482,286,939 - 82,289,413 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1482,286,939 - 82,289,374 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01487,699,481 - 87,701,956 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1487,699,494 - 87,701,884 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01481,329,774 - 81,332,224 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41488,226,209 - 88,227,102 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1481,320,317 - 81,363,808 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Mospd1l1
8 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)146875779683368335Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147341532392554092Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147341532392554092Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)147995092195876975Rat
4889951Bss92Bone structure and strength QTL 923.9tibia area (VT:1000281)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)148205747195876975Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 80 28 20 9 20 10 14 104 34 33 13 10
Low 6 6 86 62 29 62 6 8 44 36 46 9 6
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_063273786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000079338   ⟹   ENSRNOP00000073210
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1482,286,939 - 82,289,374 (-)Ensembl
Rnor_6.0 Ensembl1487,699,494 - 87,701,884 (-)Ensembl
RefSeq Acc Id: XM_063273786   ⟹   XP_063129856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81486,501,415 - 86,503,257 (-)NCBI
Protein Sequences
Protein RefSeqs XP_063129856 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000076964.1
  ENSRNOP00055043991
  ENSRNOP00065026548
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000073210   ⟸   ENSRNOT00000079338
RefSeq Acc Id: XP_063129856   ⟸   XM_063273786
Protein Domains
MSP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5RJS6-F1-model_v2 AlphaFold Q5RJS6 1-213 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699487
Promoter ID:EPDNEW_R10008
Type:single initiation site
Name:LOC686087_1
Description:similar to motile sperm domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01487,701,936 - 87,701,996EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1586609 AgrOrtholog
BioCyc Gene G2FUF-15046 BioCyc
Ensembl Genes ENSRNOG00000058316 Ensembl, ENTREZGENE
  ENSRNOG00000066239 UniProtKB/TrEMBL
  ENSRNOG00055030681 UniProtKB/Swiss-Prot
  ENSRNOG00065019698 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000102965.1 UniProtKB/TrEMBL
  ENSRNOT00055053228 UniProtKB/Swiss-Prot
  ENSRNOT00065033183 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MOSPD1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MSP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PapD-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:317312 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  rno:686087 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 686087 ENTREZGENE
PANTHER MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR34441 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Motile_Sperm UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mospd1l1 PhenoGen
PROSITE MSP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000058316 RatGTEx
  ENSRNOG00000066239 RatGTEx
  ENSRNOG00055030681 RatGTEx
  ENSRNOG00065019698 RatGTEx
Superfamily-SCOP SSF49354 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5Y568_RAT UniProtKB/TrEMBL
  A6KUJ2_RAT UniProtKB/TrEMBL
  MSPD1_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Mospd1l1  motile sperm domain containing 1 like 1  LOC686087  similar to motile sperm domain containing 1  Symbol and Name Changed 1299863 APPROVED
2006-11-19 LOC686087  similar to motile sperm domain containing 1      Symbol and Name status set to provisional 70820 PROVISIONAL