4932415M13Rikl (RIKEN cDNA 4932415M13 gene like) - Rat Genome Database

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Gene: 4932415M13Rikl (RIKEN cDNA 4932415M13 gene like) Rattus norvegicus
Analyze
No known orthologs.
Symbol: 4932415M13Rikl (Ensembl: LOC301165)
Name: RIKEN cDNA 4932415M13 gene like (Ensembl:similar to hypothetical protein 4932415M13)
RGD ID: 1564986
Description: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC301165; LOC100359586; LOC301165; MGC114490; putative sperm motility kinase W; serine/threonine-protein kinase MARK2-like; similar to hypothetical protein 4932415M13; uncharacterized protein LOC301165
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr896,944,600 - 6,966,705 (+)NCBIGRCr8
mRatBN7.296,707,991 - 6,732,613 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl96,708,011 - 6,730,700 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxPNT010000434.125,505 - 43,311 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0913,823,030 - 13,840,836 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0912,577,170 - 12,594,975 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.094,731,989 - 4,741,552 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl94,377,209 - 4,393,213 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.093,772,184 - 3,781,747 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49831,904 - 833,828 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic Map9q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics

Variants

.
Variants in 4932415M13Rikl
892 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:166
Count of miRNA genes:132
Interacting mature miRNAs:143
Transcripts:ENSRNOT00000072923
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054141Gmadr4Adrenal mass QTL 42.450.0074adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)9114209783Rat
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
1578675Bss17Bone structure and strength QTL 173.8femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)9336865213533896Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system hemolymphoid system integumental system musculoskeletal system nervous system reproductive system appendage
High
Medium 5
Low 3
Below cutoff 1 6 7 1 1 1 3 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000061893   ⟹   ENSRNOP00000058608
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl96,708,011 - 6,730,700 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000072923   ⟹   ENSRNOP00000064208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl96,708,053 - 6,725,883 (+)Ensembl
Rnor_6.0 Ensembl94,377,209 - 4,393,213 (-)Ensembl
RefSeq Acc Id: NR_172061
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr896,944,653 - 6,962,483 (+)NCBI
mRatBN7.296,708,053 - 6,725,883 (+)NCBI
RefSeq Acc Id: XR_008934173
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr896,944,600 - 6,962,483 (+)NCBI
mRatBN7.296,707,991 - 6,725,883 (+)NCBI
RefSeq Acc Id: XR_008934175
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr896,944,600 - 6,966,705 (+)NCBI
mRatBN7.296,707,991 - 6,732,613 (+)NCBI
RefSeq Acc Id: XR_008934176
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr896,944,600 - 6,962,483 (+)NCBI
mRatBN7.296,707,991 - 6,725,883 (+)NCBI
RefSeq Acc Id: XR_008934178
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr896,944,600 - 6,962,483 (+)NCBI
mRatBN7.296,707,991 - 6,725,883 (+)NCBI
RefSeq Acc Id: XR_010054573
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr896,944,600 - 6,962,483 (+)NCBI
RefSeq Acc Id: XR_010054574
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr896,944,600 - 6,960,630 (+)NCBI
RefSeq Acc Id: XR_010054575
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr896,944,600 - 6,962,483 (+)NCBI
Protein Sequences
Ensembl Protein ENSRNOP00000058608.5
  ENSRNOP00000064208.2
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000064208   ⟸   ENSRNOT00000072923
RefSeq Acc Id: ENSRNOP00000058608   ⟸   ENSRNOT00000061893
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R4C6-F1-model_v2 AlphaFold M0R4C6 1-509 view protein structure
AF-E9PSM2-F1-model_v2 AlphaFold E9PSM2 1-512 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-28392 BioCyc
Ensembl Genes ENSRNOG00000046714 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000061893.5 UniProtKB/TrEMBL
  ENSRNOT00000072923 ENTREZGENE
  ENSRNOT00000072923.2 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7455751 IMAGE-MGC_LOAD
InterPro Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
MGC_CLONE MGC:114490 IMAGE-MGC_LOAD
NCBI Gene 301165 ENTREZGENE
PANTHER GENE 10662-RELATED UniProtKB/TrEMBL
  KP78A-RELATED UniProtKB/TrEMBL
  MAP/MICROTUBULE AFFINITY-REGULATING KINASE UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen 4932415M13Rikl PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046714 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt E9PSM2_RAT UniProtKB/TrEMBL
  M0R4C6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 4932415M13Rikl  RIKEN cDNA 4932415M13 gene like  LOC301165  similar to hypothetical protein 4932415M13  Symbol and Name Changed 1299863 APPROVED
2021-03-09 LOC301165  similar to hypothetical protein 4932415M13  LOC100359586  serine/threonine-protein kinase MARK2-like  Data merged from RGD:2323608 737654 PROVISIONAL
2010-05-06 LOC100359586  serine/threonine-protein kinase MARK2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-02-09 LOC301165  similar to hypothetical protein 4932415M13      Symbol and Name status set to provisional 70820 PROVISIONAL