GRM8-AS1 (GRM8 antisense RNA 1) - Rat Genome Database

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Gene: GRM8-AS1 (GRM8 antisense RNA 1) Homo sapiens
Analyze
Symbol: GRM8-AS1
Name: GRM8 antisense RNA 1
RGD ID: 14700739
HGNC Page HGNC:40268
Description:
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387127,215,127 - 127,229,921 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7127,215,127 - 127,229,927 (+)EnsemblGRCh38hg38GRCh38
GRCh377126,855,181 - 126,869,975 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map7q31.33NCBI
HuRef7121,215,859 - 121,230,636 (+)NCBIHuRef
CHM1_17126,788,452 - 126,803,284 (+)NCBICHM1_1
T2T-CHM13v2.07128,526,795 - 128,541,594 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:12477932  


Genomics

Variants

.
Variants in GRM8-AS1
1 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 7q31.2-33(chr7:117326805-134790689)x1 copy number loss See cases [RCV000138226] Chr7:117326805..134790689 [GRCh38]
Chr7:116966859..134475440 [GRCh37]
Chr7:116754095..134125980 [NCBI36]
Chr7:7q31.2-33		 pathogenic
GRCh38/hg38 7q31.32-36.3(chr7:121863759-159335865)x3 copy number gain See cases [RCV000138847] Chr7:121863759..159335865 [GRCh38]
Chr7:121503813..159128555 [GRCh37]
Chr7:121291049..158821316 [NCBI36]
Chr7:7q31.32-36.3		 pathogenic
GRCh38/hg38 7q31.32-32.1(chr7:122018122-128907727)x1 copy number loss See cases [RCV000142521] Chr7:122018122..128907727 [GRCh38]
Chr7:121658176..128547780 [GRCh37]
Chr7:121445412..128335016 [NCBI36]
Chr7:7q31.32-32.1		 pathogenic
GRCh38/hg38 7q31.32-32.1(chr7:123829366-127947731)x1 copy number loss See cases [RCV000137416] Chr7:123829366..127947731 [GRCh38]
Chr7:123469420..127587784 [GRCh37]
Chr7:123256656..127375020 [NCBI36]
Chr7:7q31.32-32.1		 likely pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1 copy number loss See cases [RCV000052250] Chr7:53985..159282531 [GRCh38]
Chr7:53985..159075220 [GRCh37]
Chr7:149068..158767981 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7q31.33-33(chr7:124170657-134163594)x1 copy number loss See cases [RCV000142552] Chr7:124170657..134163594 [GRCh38]
Chr7:123810711..133848346 [GRCh37]
Chr7:123597947..133498886 [NCBI36]
Chr7:7q31.33-33		 pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1 copy number loss See cases [RCV000135401] Chr7:54185..159282390 [GRCh38]
Chr7:54185..159075079 [GRCh37]
Chr7:149268..158767840 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7q31.2-36.3(chr7:115459015-159325817)x3 copy number gain See cases [RCV000141413] Chr7:115459015..159325817 [GRCh38]
Chr7:115099069..159118507 [GRCh37]
Chr7:114886305..158811268 [NCBI36]
Chr7:7q31.2-36.3		 pathogenic
GRCh38/hg38 7q21.3-36.3(chr7:97419852-158923762)x3 copy number gain See cases [RCV000136717] Chr7:97419852..158923762 [GRCh38]
Chr7:97049164..158716453 [GRCh37]
Chr7:96887100..158409214 [NCBI36]
Chr7:7q21.3-36.3		 pathogenic
GRCh38/hg38 7q31.33-32.3(chr7:126859732-132750936)x1 copy number loss See cases [RCV000054171] Chr7:126859732..132750936 [GRCh38]
Chr7:126499786..132435696 [GRCh37]
Chr7:126287022..132086236 [NCBI36]
Chr7:7q31.33-32.3		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:122
Count of miRNA genes:121
Interacting mature miRNAs:121
Transcripts:ENST00000413812, ENST00000450061
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage
High
Medium 31
Low 1 1 1 2 316 1
Below cutoff 91 81 69 17 30 15 141 63 279 21 77 63 2 36 82

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000413812
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7127,215,127 - 127,229,921 (+)Ensembl
RefSeq Acc Id: ENST00000450061
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7127,215,127 - 127,229,033 (+)Ensembl
RefSeq Acc Id: ENST00000667616
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7127,215,127 - 127,229,927 (+)Ensembl
RefSeq Acc Id: NR_110194
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387127,215,127 - 127,229,921 (+)NCBI
T2T-CHM13v2.07128,526,795 - 128,541,594 (+)NCBI
Sequence:
RefSeq Acc Id: NR_110195
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387127,215,127 - 127,229,921 (+)NCBI
T2T-CHM13v2.07128,526,795 - 128,541,594 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC GRM8-AS1 COSMIC
Ensembl Genes ENSG00000236340 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000413812 ENTREZGENE
  ENST00000667616 ENTREZGENE
GTEx ENSG00000236340 GTEx
HGNC ID HGNC:40268 ENTREZGENE
Human Proteome Map GRM8-AS1 Human Proteome Map
NCBI Gene GRM8-AS1 ENTREZGENE
RNAcentral URS000075B023 RNACentral
  URS000075D3C7 RNACentral