KCTD19 (potassium channel tetramerization domain containing 19) - Rat Genome Database

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Gene: KCTD19 (potassium channel tetramerization domain containing 19) Sus scrofa
Analyze
Symbol: KCTD19
Name: potassium channel tetramerization domain containing 19
RGD ID: 14279135
Description: ENCODES a protein that exhibits cullin family protein binding (inferred); INVOLVED IN male meiotic nuclear division (inferred); protein homooligomerization (inferred); ubiquitin-dependent protein catabolic process (inferred); ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); Cerebral Visual Impairment and Intellectual Disability (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BTB/POZ domain-containing protein KCTD19
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl627,931,930 - 27,966,277 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1627,932,783 - 27,966,294 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2625,200,078 - 25,233,394 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
KCTD19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl627,931,930 - 27,966,277 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1627,932,783 - 27,966,294 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2625,200,078 - 25,233,394 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCTD19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381667,289,432 - 67,326,741 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1667,289,428 - 67,326,760 (-)EnsemblGRCh38hg38GRCh38
GRCh371667,323,335 - 67,360,644 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361665,880,894 - 65,918,162 (-)NCBINCBI36Build 36hg18NCBI36
Celera1651,831,659 - 51,868,918 (-)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1653,196,456 - 53,233,724 (-)NCBIHuRef
CHM1_11668,730,749 - 68,768,015 (-)NCBICHM1_1
T2T-CHM13v2.01673,083,729 - 73,121,039 (-)NCBIT2T-CHM13v2.0
Kctd19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398106,109,433 - 106,140,134 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8106,109,439 - 106,140,134 (-)EnsemblGRCm39 Ensembl
GRCm388105,382,801 - 105,413,502 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8105,382,807 - 105,413,502 (-)EnsemblGRCm38mm10GRCm38
MGSCv378107,906,712 - 107,937,387 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368108,271,941 - 108,302,616 (-)NCBIMGSCv36mm8
Celera8109,605,959 - 109,636,599 (-)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.04NCBI
Kctd19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81950,169,814 - 50,202,121 (-)NCBIGRCr8
mRatBN7.21933,259,869 - 33,292,011 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,259,970 - 33,292,006 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1940,075,570 - 40,107,604 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01940,728,896 - 40,760,929 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01943,017,883 - 43,049,714 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,338,399 - 37,370,438 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,337,639 - 37,370,429 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01948,203,745 - 48,236,110 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41935,197,670 - 35,230,132 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1932,688,418 - 32,720,316 (-)NCBICelera
Cytogenetic Map19q12NCBI
Kctd19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554849,310,147 - 9,344,882 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554849,282,976 - 9,344,882 (+)NCBIChiLan1.0ChiLan1.0
KCTD19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21876,818,696 - 76,856,046 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11682,731,348 - 82,768,754 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01647,634,636 - 47,671,934 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11667,023,849 - 67,061,230 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1667,023,847 - 67,061,230 (-)Ensemblpanpan1.1panPan2
KCTD19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1582,060,946 - 82,093,248 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl582,061,449 - 82,093,246 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha582,050,522 - 82,082,832 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0582,496,190 - 82,528,486 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl582,496,688 - 82,528,484 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1582,322,300 - 82,354,589 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0582,007,860 - 82,040,165 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0582,647,106 - 82,679,410 (+)NCBIUU_Cfam_GSD_1.0
Kctd19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934941,812,405 - 41,843,076 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647517,744,645 - 17,814,726 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647517,746,121 - 17,776,537 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCTD19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1560,126,657 - 60,164,880 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl560,132,938 - 60,165,570 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604722,879,382 - 22,917,922 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kctd19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474619,005,068 - 19,036,989 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474619,004,964 - 19,037,146 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in KCTD19
555 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system musculoskeletal system nervous system
High
Medium
Low 1 1
Below cutoff 2 2 3 1 9

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000003079   ⟹   ENSSSCP00000003000
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl627,931,930 - 27,966,277 (-)Ensembl
RefSeq Acc Id: XM_003126929   ⟹   XP_003126977
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1627,932,783 - 27,966,294 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005664423   ⟹   XP_005664480
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1627,932,783 - 27,966,294 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013998242   ⟹   XP_013853696
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1627,932,783 - 27,966,294 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005664480   ⟸   XM_005664423
- Peptide Label: isoform X3
- UniProtKB: A0A8D0V1Y6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013853696   ⟸   XM_013998242
- Peptide Label: isoform X2
- UniProtKB: A0A8D0V1Y6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003126977   ⟸   XM_003126929
- Peptide Label: isoform X1
- UniProtKB: F1RFX6 (UniProtKB/TrEMBL),   A0A8D0V1Y6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000003000   ⟸   ENSSSCT00000003079
Protein Domains
Potassium channel tetramerisation-type BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000002781 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015062407 UniProtKB/TrEMBL
  ENSSSCG00025075315 UniProtKB/TrEMBL
  ENSSSCG00035041779 UniProtKB/TrEMBL
  ENSSSCG00060052717 UniProtKB/TrEMBL
  ENSSSCG00065009756 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000003079 ENTREZGENE
  ENSSSCT00000003079.5 UniProtKB/TrEMBL
  ENSSSCT00015083724.1 UniProtKB/TrEMBL
  ENSSSCT00025104000.1 UniProtKB/TrEMBL
  ENSSSCT00035055570.1 UniProtKB/TrEMBL
  ENSSSCT00060071782.1 UniProtKB/TrEMBL
  ENSSSCT00065012977.1 UniProtKB/TrEMBL
InterPro SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  T1-type_BTB UniProtKB/TrEMBL
NCBI Gene KCTD19 ENTREZGENE
PANTHER BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD6 UniProtKB/TrEMBL
  POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING UniProtKB/TrEMBL
Pfam BTB_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/TrEMBL
UniProt A0A8D0V1Y6 ENTREZGENE, UniProtKB/TrEMBL
  F1RFX6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:89397 ENTREZGENE