DEFB121 (defensin beta 121) - Rat Genome Database

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Gene: DEFB121 (defensin beta 121) Sus scrofa
Analyze
Symbol: DEFB121
Name: defensin beta 121
RGD ID: 14264153
Description: INVOLVED IN defense response to bacterium (inferred); innate immune response (inferred); FOUND IN extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BD123; beta-defensin 121; prepro-beta-defensin 123 protein
RGD Orthologs
Human
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1735,154,178 - 35,155,737 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11735,154,177 - 35,155,772 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21739,907,588 - 39,909,158 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:16596454   PMID:22301074  


Genomics

Comparative Map Data
DEFB121
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1735,154,178 - 35,155,737 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11735,154,177 - 35,155,772 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21739,907,588 - 39,909,158 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DEFB121
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382031,404,845 - 31,418,522 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2031,404,845 - 31,412,838 (-)EnsemblGRCh38hg38GRCh38
GRCh372029,992,648 - 30,000,641 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362029,456,361 - 29,457,651 (-)NCBINCBI36Build 36hg18NCBI36
Build 342029,456,360 - 29,457,651NCBI
Celera2026,748,893 - 26,756,886 (-)NCBICelera
Cytogenetic Map20q11.21NCBI
HuRef2026,781,405 - 26,789,398 (-)NCBIHuRef
CHM1_12029,896,619 - 29,904,612 (-)NCBICHM1_1
T2T-CHM13v2.02033,129,041 - 33,142,726 (-)NCBIT2T-CHM13v2.0
Defb121
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542229,525,435 - 29,526,857 (+)NCBIChiLan1.0ChiLan1.0
DEFB121
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22137,102,303 - 37,110,292 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12037,095,400 - 37,103,389 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02027,700,176 - 27,708,166 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12028,336,247 - 28,344,230 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2028,336,247 - 28,344,598 (-)Ensemblpanpan1.1panPan2
DEFB121
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12420,924,129 - 20,928,918 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2420,927,337 - 20,929,231 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2420,573,192 - 20,577,350 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02421,611,356 - 21,616,160 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2421,614,581 - 21,616,016 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12420,889,668 - 20,894,472 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02420,995,331 - 20,999,483 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02421,425,391 - 21,429,607 (-)NCBIUU_Cfam_GSD_1.0
Defb121
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640170,009,788 - 170,011,728 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648518,441,152 - 18,443,116 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DEFB121
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl235,826,052 - 35,827,289 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605091,124,277 - 91,132,197 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in DEFB121
62 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

renal system
High
Medium
Low 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000025432   ⟹   ENSSSCP00000020510
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1735,154,518 - 35,155,738 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000102682   ⟹   ENSSSCP00000075732
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1735,154,178 - 35,155,737 (-)Ensembl
RefSeq Acc Id: XM_005654238   ⟹   XP_005654295
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11735,154,177 - 35,155,772 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005654295 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein DAA05755 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000075732
  ENSSSCP00000075732.1
Reference Protein Sequences
RefSeq Acc Id: XP_005654295   ⟸   XM_005654238
- UniProtKB: A0A8E8LS78 (UniProtKB/TrEMBL),   Q1RLJ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000020510   ⟸   ENSSSCT00000025432
RefSeq Acc Id: ENSSSCP00000075732   ⟸   ENSSSCT00000102682
Protein Domains
Beta-defensin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000028629 Ensembl
  ENSSSCG00000062567 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000102682 ENTREZGENE
  ENSSSCT00000102682.1 UniProtKB/TrEMBL
InterPro Beta_defensin UniProtKB/TrEMBL
KEGG Report ssc:100188899 UniProtKB/TrEMBL
NCBI Gene DEFB121 ENTREZGENE
PANTHER BETA-DEFENSIN 121 UniProtKB/TrEMBL
  BETA-DEFENSIN 123-RELATED UniProtKB/TrEMBL
Pfam Defensin_beta_2 UniProtKB/TrEMBL
UniProt A0A8E8LS78 ENTREZGENE, UniProtKB/TrEMBL
  Q1RLJ6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:97962 ENTREZGENE