INHA (inhibin subunit alpha) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: INHA (inhibin subunit alpha) Sus scrofa
Analyze
Symbol: INHA
Name: inhibin subunit alpha
RGD ID: 14247253
Description: ENCODES a protein that exhibits inhibin binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN hemoglobin biosynthetic process (ortholog); male gonad development (ortholog); negative regulation of follicle-stimulating hormone secretion (ortholog); ASSOCIATED WITH dysgerminoma (ortholog); embryonal carcinoma (ortholog); Endometrial Neoplasms (ortholog); FOUND IN extracellular space (ortholog); inhibin A complex (ortholog); inhibin B complex (ortholog); INTERACTS WITH lead diacetate
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: inhibin alpha chain; inhibin alpha subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15121,580,803 - 121,586,006 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115121,581,847 - 121,586,020 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215134,507,304 - 134,511,349 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap15q2.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:2417121   PMID:3016724   PMID:8661698   PMID:10341086   PMID:12030943   PMID:14681463   PMID:16879365   PMID:17132910   PMID:22301074   PMID:23226944   PMID:26097017   PMID:26208435  
PMID:26521695   PMID:28082104   PMID:30032202   PMID:34502034  


Genomics

Comparative Map Data
INHA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15121,580,803 - 121,586,006 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115121,581,847 - 121,586,020 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215134,507,304 - 134,511,349 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap15q2.5NCBI
INHA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,572,310 - 219,575,711 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2219,569,162 - 219,575,711 (+)EnsemblGRCh38hg38GRCh38
GRCh372220,437,032 - 220,440,433 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362220,145,198 - 220,148,671 (+)NCBINCBI36Build 36hg18NCBI36
Build 342220,262,458 - 220,265,932NCBI
Celera2214,206,917 - 214,210,389 (+)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2212,289,982 - 212,293,463 (+)NCBIHuRef
CHM1_12220,442,773 - 220,446,254 (+)NCBICHM1_1
T2T-CHM13v2.02220,057,015 - 220,060,416 (+)NCBIT2T-CHM13v2.0
Inha
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39175,483,872 - 75,487,010 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl175,483,721 - 75,487,010 (+)EnsemblGRCm39 Ensembl
GRCm38175,507,077 - 75,510,366 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl175,507,077 - 75,510,366 (+)EnsemblGRCm38mm10GRCm38
MGSCv37175,503,652 - 75,506,929 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36175,390,225 - 75,393,502 (+)NCBIMGSCv36mm8
Celera175,996,369 - 75,999,645 (+)NCBICelera
Cytogenetic Map1C4NCBI
cM Map139.16NCBI
Inha
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8984,443,109 - 84,446,010 (+)NCBIGRCr8
mRatBN7.2976,994,465 - 76,997,366 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl976,993,589 - 76,997,248 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx985,438,700 - 85,441,597 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0990,567,579 - 90,570,476 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0988,953,758 - 88,956,655 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0982,700,482 - 82,703,383 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl982,700,468 - 82,703,400 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0982,469,743 - 82,472,644 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4974,781,223 - 74,784,124 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1974,928,355 - 74,931,217 (+)NCBI
Celera974,564,342 - 74,567,243 (+)NCBICelera
Cytogenetic Map9q33NCBI
Inha
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545313,902,277 - 13,905,008 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545313,902,443 - 13,905,008 (-)NCBIChiLan1.0ChiLan1.0
INHA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213122,201,726 - 122,205,889 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B122,216,786 - 122,220,855 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B106,828,948 - 106,832,993 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B225,419,747 - 225,423,386 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B225,419,176 - 225,423,386 (+)Ensemblpanpan1.1panPan2
INHA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13726,080,465 - 26,083,570 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3726,080,510 - 26,083,391 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3726,905,885 - 26,908,990 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03726,095,548 - 26,098,652 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3726,095,593 - 26,098,473 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13725,999,522 - 26,002,625 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03725,935,517 - 25,938,622 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03725,956,124 - 25,959,282 (+)NCBIUU_Cfam_GSD_1.0
Inha
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303175,606,985 - 175,611,402 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365691,950,297 - 1,954,165 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365691,949,747 - 1,954,179 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INHA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110105,467,575 - 105,471,388 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10105,467,963 - 105,471,688 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604093,930,128 - 93,933,947 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Inha
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248235,487,278 - 5,491,635 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248235,487,930 - 5,491,447 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in INHA
140 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system nervous system reproductive system
High
Medium
Low 2
Below cutoff 1 12 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_214189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021074693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF510728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK234503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK235034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK347411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK394852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK394935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK395463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK400634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK400739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY028465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY028466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ356013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU847280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FP565246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M13980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X03265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000031176   ⟹   ENSSSCP00000021670
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15121,580,803 - 121,586,006 (+)Ensembl
RefSeq Acc Id: NM_214189   ⟹   NP_999354
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115121,581,977 - 121,586,020 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021074693   ⟹   XP_020930352
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115121,581,847 - 121,586,010 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020930352   ⟸   XM_021074693
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_999354   ⟸   NM_214189
- Peptide Label: precursor
- UniProtKB: Q2I0D4 (UniProtKB/Swiss-Prot),   P04087 (UniProtKB/Swiss-Prot),   A0A480NX98 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000021670   ⟸   ENSSSCT00000031176
Protein Domains
TGF-beta family profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000020771 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSSSCG00005006134 UniProtKB/Swiss-Prot
  ENSSSCG00015038605 UniProtKB/Swiss-Prot
  ENSSSCG00025012180 UniProtKB/Swiss-Prot
  ENSSSCG00030009605 UniProtKB/Swiss-Prot
  ENSSSCG00035010763 UniProtKB/Swiss-Prot
  ENSSSCG00040022088 UniProtKB/Swiss-Prot
  ENSSSCG00045030122 UniProtKB/Swiss-Prot
  ENSSSCG00055003175 UniProtKB/Swiss-Prot
  ENSSSCG00060070487 UniProtKB/Swiss-Prot
  ENSSSCG00065030658 UniProtKB/Swiss-Prot
  ENSSSCG00070015921 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000031176 ENTREZGENE
  ENSSSCT00000031176.4 UniProtKB/Swiss-Prot
  ENSSSCT00005009325.1 UniProtKB/Swiss-Prot
  ENSSSCT00015051408.1 UniProtKB/Swiss-Prot
  ENSSSCT00025016118.1 UniProtKB/Swiss-Prot
  ENSSSCT00030013150.1 UniProtKB/Swiss-Prot
  ENSSSCT00035013462.1 UniProtKB/Swiss-Prot
  ENSSSCT00040029621.1 UniProtKB/Swiss-Prot
  ENSSSCT00045051365.1 UniProtKB/Swiss-Prot
  ENSSSCT00055006153.1 UniProtKB/Swiss-Prot
  ENSSSCT00060096207.1 UniProtKB/Swiss-Prot
  ENSSSCT00065041439.1 UniProtKB/Swiss-Prot
  ENSSSCT00070031278.1 UniProtKB/Swiss-Prot
Gene3D-CATH 2.10.90.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Inhibin_asu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGF-b_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGF-beta-rel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGFb_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397386 UniProtKB/Swiss-Prot
NCBI Gene INHA ENTREZGENE
PANTHER PTHR11848 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11848:SF117 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TGF_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF Inhibin_alpha_subunit UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS INHIBINA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TGF_BETA_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGF_BETA_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART TGFB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A480NX98 ENTREZGENE, UniProtKB/TrEMBL
  B5AFX1_PIG UniProtKB/TrEMBL
  INHA_PIG UniProtKB/Swiss-Prot, ENTREZGENE
  Q2I0D4 ENTREZGENE
  Q8SPF4_PIG UniProtKB/TrEMBL
UniProt Secondary Q2I0D4 UniProtKB/Swiss-Prot
VGNC ID VGNC:96372 ENTREZGENE