BFSP1 (beaded filament structural protein 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: BFSP1 (beaded filament structural protein 1) Sus scrofa
Analyze
Symbol: BFSP1
Name: beaded filament structural protein 1
RGD ID: 14224252
Description: ENCODES a protein that exhibits structural constituent of eye lens (inferred); INVOLVED IN cell maturation (ortholog); lens fiber cell development (ortholog); ASSOCIATED WITH cataract (ortholog); cataract 33 (ortholog); coloboma (ortholog); FOUND IN cell cortex (inferred); cytoplasm (inferred); cytoskeleton (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: filensin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1725,933,900 - 25,967,005 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11725,933,743 - 25,966,940 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21729,343,023 - 29,376,119 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
BFSP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1725,933,900 - 25,967,005 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11725,933,743 - 25,966,940 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21729,343,023 - 29,376,119 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BFSP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382017,493,905 - 17,569,220 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2017,493,905 - 17,569,220 (-)EnsemblGRCh38hg38GRCh38
GRCh372017,474,550 - 17,549,865 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362017,422,550 - 17,459,974 (-)NCBINCBI36Build 36hg18NCBI36
Build 342017,422,550 - 17,459,974NCBI
Celera2017,549,027 - 17,614,092 (-)NCBICelera
Cytogenetic Map20p12.1NCBI
HuRef2017,437,512 - 17,512,555 (-)NCBIHuRef
CHM1_12017,474,583 - 17,549,870 (-)NCBICHM1_1
T2T-CHM13v2.02017,544,579 - 17,619,878 (-)NCBIT2T-CHM13v2.0
Bfsp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392143,668,448 - 143,757,320 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2143,668,448 - 143,705,093 (-)EnsemblGRCm39 Ensembl
GRCm382143,826,528 - 143,915,219 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2143,826,528 - 143,863,173 (-)EnsemblGRCm38mm10GRCm38
MGSCv372143,652,264 - 143,688,909 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362143,517,969 - 143,554,614 (-)NCBIMGSCv36mm8
Celera2145,009,411 - 145,046,263 (-)NCBICelera
Cytogenetic Map2G1NCBI
cM Map270.89NCBI
Bfsp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83151,648,588 - 151,706,153 (-)NCBIGRCr8
mRatBN7.23131,195,087 - 131,252,668 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3131,195,087 - 131,229,337 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3135,118,796 - 135,153,286 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03143,702,870 - 143,737,362 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03141,406,079 - 141,440,571 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03137,935,345 - 137,992,652 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3137,935,345 - 137,969,658 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03144,374,721 - 144,424,049 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43132,268,138 - 132,302,378 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13132,173,710 - 132,207,951 (-)NCBI
Celera3130,092,931 - 130,121,949 (-)NCBICelera
Cytogenetic Map3q41NCBI
Bfsp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541526,507,528 - 26,535,551 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541526,507,381 - 26,535,545 (-)NCBIChiLan1.0ChiLan1.0
BFSP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22118,382,481 - 18,425,974 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12018,379,319 - 18,422,812 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02017,452,664 - 17,527,917 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12017,430,466 - 17,505,954 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2017,430,635 - 17,467,819 (-)Ensemblpanpan1.1panPan2
BFSP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1245,432,098 - 5,500,278 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl245,439,512 - 5,499,307 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha245,364,812 - 5,432,325 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0245,840,195 - 5,907,896 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl245,839,364 - 5,907,718 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1245,484,491 - 5,521,881 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0245,547,459 - 5,614,907 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0245,823,137 - 5,890,458 (+)NCBIUU_Cfam_GSD_1.0
Bfsp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640154,106,016 - 154,168,580 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364852,566,521 - 2,600,030 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364852,566,698 - 2,599,946 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BFSP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1246,558,767 - 46,596,962 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660781,225,801 - 1,264,218 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bfsp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474118,653,108 - 18,681,652 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474118,652,956 - 18,682,307 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in BFSP1
1678 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system nervous system renal system reproductive system
High
Medium
Low 8 1
Below cutoff 3 1 9 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000007756   ⟹   ENSSSCP00000007547
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1725,933,900 - 25,967,005 (-)Ensembl
RefSeq Acc Id: XM_013985099   ⟹   XP_013840553
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11725,933,743 - 25,966,938 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021077954   ⟹   XP_020933613
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11725,933,743 - 25,966,940 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013840553 (Get FASTA)   NCBI Sequence Viewer  
  XP_020933613 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000007547
  ENSSSCP00000007547.5
  ENSSSCP00060005319.1
Reference Protein Sequences
RefSeq Acc Id: XP_020933613   ⟸   XM_021077954
- Peptide Label: isoform X2
- UniProtKB: A0A8D1UHS4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013840553   ⟸   XM_013985099
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSSSCP00000007547   ⟸   ENSSSCT00000007756
Protein Domains
IF rod


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000007084 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00060010674 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000007756 ENTREZGENE
  ENSSSCT00000007756.5 UniProtKB/TrEMBL
  ENSSSCT00060013887.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  Vasodilator-stimulated phosphoprotein UniProtKB/TrEMBL
InterPro BFSP1 UniProtKB/TrEMBL
  IF_rod_dom UniProtKB/TrEMBL
NCBI Gene BFSP1 ENTREZGENE
PANTHER FILENSIN UniProtKB/TrEMBL
  PTHR14069 UniProtKB/TrEMBL
Pfam Filament UniProtKB/TrEMBL
PROSITE IF_ROD_2 UniProtKB/TrEMBL
SMART Filament UniProtKB/TrEMBL
Superfamily-SCOP Intermediate filament protein, coiled coil region UniProtKB/TrEMBL
UniProt A0A8D1UHS4 ENTREZGENE, UniProtKB/TrEMBL
  F1SBI4_PIG UniProtKB/TrEMBL
VGNC ID VGNC:95472 ENTREZGENE