PRPSAP1 (phosphoribosyl pyrophosphate synthetase associated protein 1) - Rat Genome Database

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Gene: PRPSAP1 (phosphoribosyl pyrophosphate synthetase associated protein 1) Sus scrofa
Analyze
Symbol: PRPSAP1
Name: phosphoribosyl pyrophosphate synthetase associated protein 1
RGD ID: 14217189
Description: ENCODES a protein that exhibits enzyme regulator activity (ortholog); kinase binding (ortholog); INVOLVED IN negative regulation of kinase activity (ortholog); FOUND IN protein-containing complex (ortholog); ribose phosphate diphosphokinase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphoribosyl pyrophosphate synthase-associated protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,144,069 - 5,174,382 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,141,223 - 5,174,383 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,047,807 - 5,078,207 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PRPSAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,144,069 - 5,174,382 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,141,223 - 5,174,383 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,047,807 - 5,078,207 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRPSAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381776,309,478 - 76,354,198 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1776,309,478 - 76,384,521 (-)EnsemblGRCh38hg38GRCh38
GRCh371774,305,559 - 74,350,279 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,818,610 - 71,861,526 (-)NCBINCBI36Build 36hg18NCBI36
Build 341771,818,609 - 71,861,526NCBI
Celera1770,901,207 - 70,943,527 (-)NCBICelera
Cytogenetic Map17q25.1NCBI
HuRef1769,735,400 - 69,778,716 (-)NCBIHuRef
CHM1_11774,371,766 - 74,415,154 (-)NCBICHM1_1
T2T-CHM13v2.01777,206,033 - 77,250,766 (-)NCBIT2T-CHM13v2.0
Prpsap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911116,361,641 - 116,385,739 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11116,361,671 - 116,385,461 (-)EnsemblGRCm39 Ensembl
GRCm3811116,470,816 - 116,494,913 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11116,470,845 - 116,494,202 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711116,332,130 - 116,351,660 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611116,286,588 - 116,315,017 (-)NCBIMGSCv36mm8
Celera11128,239,926 - 128,259,180 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1181.34NCBI
Prpsap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810102,199,949 - 102,221,642 (-)NCBIGRCr8
mRatBN7.210101,701,094 - 101,750,753 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10101,701,096 - 101,750,751 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10106,757,499 - 106,779,133 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010106,220,577 - 106,242,211 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010101,621,981 - 101,643,676 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010105,430,516 - 105,492,154 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10105,430,520 - 105,452,228 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010105,092,063 - 105,113,772 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410106,582,381 - 106,604,072 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110106,596,897 - 106,618,475 (-)NCBI
Celera10100,273,440 - 100,295,162 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Prpsap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555065,951,210 - 5,987,658 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555065,951,210 - 5,987,658 (+)NCBIChiLan1.0ChiLan1.0
PRPSAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21992,353,684 - 92,397,196 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11797,178,894 - 97,222,407 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01770,258,663 - 70,302,287 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11775,810,423 - 75,853,442 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1775,810,423 - 75,853,442 (-)Ensemblpanpan1.1panPan2
PRPSAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.194,346,282 - 4,372,067 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl94,346,297 - 4,372,067 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,026,361 - 5,052,101 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.095,018,066 - 5,042,293 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl95,018,081 - 5,042,694 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.195,056,383 - 5,082,115 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.095,166,189 - 5,191,954 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.095,239,252 - 5,251,685 (+)NCBIUU_Cfam_GSD_1.0
Prpsap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056024,960,002 - 4,985,410 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365941,427,122 - 1,456,562 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365941,426,549 - 1,451,984 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRPSAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11645,326,152 - 45,368,636 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1645,314,259 - 45,370,274 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607716,068,148 - 16,113,868 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prpsap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248016,177,277 - 6,206,786 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248016,177,277 - 6,206,846 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PRPSAP1
1632 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 9 4 3 5 2 23 2 3 3
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000018709   ⟹   ENSSSCP00000018208
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl125,144,069 - 5,174,382 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000063667   ⟹   ENSSSCP00000037846
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl125,144,069 - 5,174,382 (+)Ensembl
RefSeq Acc Id: XM_003131174   ⟹   XP_003131222
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1125,144,058 - 5,174,383 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005656921   ⟹   XP_005656978
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1125,144,058 - 5,174,375 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021066595   ⟹   XP_020922254
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1125,141,223 - 5,174,375 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020922254   ⟸   XM_021066595
- Peptide Label: isoform X2
- UniProtKB: A0A8D0I851 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003131222   ⟸   XM_003131174
- Peptide Label: isoform X1
- UniProtKB: F1RWP0 (UniProtKB/TrEMBL),   A0A4X1UUX0 (UniProtKB/TrEMBL),   A0A8D0V8F2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005656978   ⟸   XM_005656921
- Peptide Label: isoform X2
- UniProtKB: A0A8D0I851 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000018208   ⟸   ENSSSCT00000018709
RefSeq Acc Id: ENSSSCP00000037846   ⟸   ENSSSCT00000063667
Protein Domains
Ribose-phosphate pyrophosphokinase N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000017184 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005008566 UniProtKB/TrEMBL
  ENSSSCG00025049838 UniProtKB/TrEMBL
  ENSSSCG00030003917 UniProtKB/TrEMBL
  ENSSSCG00035055901 UniProtKB/TrEMBL
  ENSSSCG00040074913 UniProtKB/TrEMBL
  ENSSSCG00045036241 UniProtKB/TrEMBL
  ENSSSCG00050014063 UniProtKB/TrEMBL
  ENSSSCG00055009076 UniProtKB/TrEMBL
  ENSSSCG00060064903 UniProtKB/TrEMBL
  ENSSSCG00065064775 UniProtKB/TrEMBL
  ENSSSCG00070020033 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000018709 ENTREZGENE
  ENSSSCT00000018709.4 UniProtKB/TrEMBL
  ENSSSCT00000063667.3 UniProtKB/TrEMBL
  ENSSSCT00005013140.1 UniProtKB/TrEMBL
  ENSSSCT00025068065.1 UniProtKB/TrEMBL
  ENSSSCT00030005121.1 UniProtKB/TrEMBL
  ENSSSCT00030005133.1 UniProtKB/TrEMBL
  ENSSSCT00035074588.1 UniProtKB/TrEMBL
  ENSSSCT00040103735.1 UniProtKB/TrEMBL
  ENSSSCT00040103762.1 UniProtKB/TrEMBL
  ENSSSCT00045062380.1 UniProtKB/TrEMBL
  ENSSSCT00050018970.1 UniProtKB/TrEMBL
  ENSSSCT00050018982.1 UniProtKB/TrEMBL
  ENSSSCT00055017824.1 UniProtKB/TrEMBL
  ENSSSCT00060088601.1 UniProtKB/TrEMBL
  ENSSSCT00065088912.1 UniProtKB/TrEMBL
  ENSSSCT00070039715.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.2020 UniProtKB/TrEMBL
InterPro Pribosyltran_N UniProtKB/TrEMBL
  PRibTrfase_dom UniProtKB/TrEMBL
  PRTase-like UniProtKB/TrEMBL
  Rib-P_diPkinase UniProtKB/TrEMBL
KEGG Report ssc:100517776 UniProtKB/TrEMBL
NCBI Gene PRPSAP1 ENTREZGENE
PANTHER PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE-ASSOCIATED PROTEIN 1 UniProtKB/TrEMBL
  PTHR10210 UniProtKB/TrEMBL
Pfam Pribosyl_synth UniProtKB/TrEMBL
  Pribosyltran_N UniProtKB/TrEMBL
SMART Pribosyltran_N UniProtKB/TrEMBL
Superfamily-SCOP SSF53271 UniProtKB/TrEMBL
UniProt A0A287A1P5_PIG UniProtKB/TrEMBL
  A0A4X1UUX0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0I851 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0SAK2_PIG UniProtKB/TrEMBL
  A0A8D0V8F2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1G695_PIG UniProtKB/TrEMBL
  F1RWP0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:91849 ENTREZGENE