LOC100517145 (complement C3) - Rat Genome Database

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Pathways
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Gene: LOC100517145 (complement C3) Sus scrofa
Analyze
Symbol: LOC100517145
Name: complement C3
RGD ID: 14209549
Description: ENCODES a protein that exhibits endopeptidase inhibitor activity (inferred); INVOLVED IN complement activation, alternative pathway (inferred); complement activation, classical pathway (inferred); inflammatory response (inferred); FOUND IN extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1268,890,218 - 68,920,763 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2269,218,486 - 69,248,943 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074  


Genomics

Comparative Map Data
LOC100517145
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1268,890,218 - 68,920,763 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2269,218,486 - 69,248,943 (+)NCBISscrofa10.2Sscrofa10.2susScr3
C3P1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,041,356 - 10,074,138 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1910,037,803 - 10,074,135 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl1910,041,841 - 10,074,770 (+)EnsemblGRCh38hg38GRCh38
GRCh371910,152,032 - 10,184,814 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,013,032 - 10,045,811 (+)NCBINCBI36Build 36hg18NCBI36
Celera1910,047,526 - 10,080,306 (+)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef199,732,544 - 9,765,101 (+)NCBIHuRef
CHM1_11910,151,844 - 10,185,085 (+)NCBICHM1_1
T2T-CHM13v2.01910,167,564 - 10,200,369 (+)NCBIT2T-CHM13v2.0

Variants

.
Variants in LOC100517145
513 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system nervous system reproductive system
High
Medium
Low 1
Below cutoff 1 4

Sequence


Reference Sequences
RefSeq Acc Id: XM_005654852   ⟹   XP_005654909
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1268,890,218 - 68,920,763 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005654909   ⟸   XM_005654852
- UniProtKB: F1S3H9 (UniProtKB/TrEMBL),   A0A4X1V0B2 (UniProtKB/TrEMBL),   A0A480I0T0 (UniProtKB/TrEMBL),   A0A8D1JDJ7 (UniProtKB/TrEMBL),   A0A8D0JNM5 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Anaphylatoxin-like   NTR


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000013665 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005028618 UniProtKB/TrEMBL
  ENSSSCG00015068297 UniProtKB/TrEMBL
  ENSSSCG00025053004 UniProtKB/TrEMBL
  ENSSSCG00035014987 UniProtKB/TrEMBL
  ENSSSCG00040002014 UniProtKB/TrEMBL
  ENSSSCG00045039481 UniProtKB/TrEMBL
  ENSSSCG00055029917 UniProtKB/TrEMBL
  ENSSSCG00060045173 UniProtKB/TrEMBL
  ENSSSCG00065058135 UniProtKB/TrEMBL
  ENSSSCG00070019874 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000014929 ENTREZGENE
  ENSSSCT00000014929.5 UniProtKB/TrEMBL
  ENSSSCT00000037204.3 UniProtKB/TrEMBL
  ENSSSCT00000052304.3 UniProtKB/TrEMBL
  ENSSSCT00000064148.3 UniProtKB/TrEMBL
  ENSSSCT00000073176.2 UniProtKB/TrEMBL
  ENSSSCT00005048242.1 UniProtKB/TrEMBL
  ENSSSCT00005048367.1 UniProtKB/TrEMBL
  ENSSSCT00005048399.1 UniProtKB/TrEMBL
  ENSSSCT00005048422.1 UniProtKB/TrEMBL
  ENSSSCT00015091576.1 UniProtKB/TrEMBL
  ENSSSCT00015092128.1 UniProtKB/TrEMBL
  ENSSSCT00025072609.1 UniProtKB/TrEMBL
  ENSSSCT00025073543.1 UniProtKB/TrEMBL
  ENSSSCT00025074038.1 UniProtKB/TrEMBL
  ENSSSCT00035019050.1 UniProtKB/TrEMBL
  ENSSSCT00035019062.1 UniProtKB/TrEMBL
  ENSSSCT00035019082.1 UniProtKB/TrEMBL
  ENSSSCT00040002478.1 UniProtKB/TrEMBL
  ENSSSCT00040002536.1 UniProtKB/TrEMBL
  ENSSSCT00040002598.1 UniProtKB/TrEMBL
  ENSSSCT00045068787.1 UniProtKB/TrEMBL
  ENSSSCT00045068801.1 UniProtKB/TrEMBL
  ENSSSCT00055059545.1 UniProtKB/TrEMBL
  ENSSSCT00055059639.1 UniProtKB/TrEMBL
  ENSSSCT00055059684.1 UniProtKB/TrEMBL
  ENSSSCT00060061298.1 UniProtKB/TrEMBL
  ENSSSCT00060061339.1 UniProtKB/TrEMBL
  ENSSSCT00065079557.1 UniProtKB/TrEMBL
  ENSSSCT00065079571.1 UniProtKB/TrEMBL
  ENSSSCT00065079576.1 UniProtKB/TrEMBL
  ENSSSCT00070041024.1 UniProtKB/TrEMBL
  ENSSSCT00070041250.1 UniProtKB/TrEMBL
  ENSSSCT00070041366.1 UniProtKB/TrEMBL
  ENSSSCT00070041476.1 UniProtKB/TrEMBL
Gene3D-CATH 1.50.10.20 UniProtKB/TrEMBL
  2.20.130.20 UniProtKB/TrEMBL
  2.40.50.120 UniProtKB/TrEMBL
  2.60.120.1540 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  2.60.40.1930 UniProtKB/TrEMBL
  2.60.40.1940 UniProtKB/TrEMBL
  2.60.40.690 UniProtKB/TrEMBL
  6.20.50.160 UniProtKB/TrEMBL
  Anaphylotoxins (complement system) UniProtKB/TrEMBL
InterPro A-macroglobulin_rcpt-bd UniProtKB/TrEMBL
  A-macroglobulin_rcpt-bd_sf UniProtKB/TrEMBL
  A2M_N_BRD UniProtKB/TrEMBL
  Alpha-macroglob_thiol-ester_cl UniProtKB/TrEMBL
  Alpha-macroglobulin_TED UniProtKB/TrEMBL
  Anaphylatoxin/fibulin UniProtKB/TrEMBL
  Anaphylatoxin_comp_syst UniProtKB/TrEMBL
  C3/4/5_MG1 UniProtKB/TrEMBL
  C3_CUB2 UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Macroglobln_a2 UniProtKB/TrEMBL
  MG2 UniProtKB/TrEMBL
  MG3 UniProtKB/TrEMBL
  MG4 UniProtKB/TrEMBL
  Netrin_domain UniProtKB/TrEMBL
  Netrin_module_non-TIMP UniProtKB/TrEMBL
  Terpenoid_cyclase/PrenylTrfase UniProtKB/TrEMBL
  TIMP-like_OB-fold UniProtKB/TrEMBL
KEGG Report ssc:100517145 UniProtKB/TrEMBL
NCBI Gene LOC100517145 ENTREZGENE
PANTHER ANAPHYLATOXIN-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  MACROGLOBULIN / COMPLEMENT UniProtKB/TrEMBL
Pfam A2M UniProtKB/TrEMBL
  A2M_BRD UniProtKB/TrEMBL
  A2M_recep UniProtKB/TrEMBL
  ANATO UniProtKB/TrEMBL
  C3_CUB2 UniProtKB/TrEMBL
  MG1 UniProtKB/TrEMBL
  MG2 UniProtKB/TrEMBL
  MG3 UniProtKB/TrEMBL
  MG4 UniProtKB/TrEMBL
  NTR UniProtKB/TrEMBL
  TED_complement UniProtKB/TrEMBL
PROSITE ANAPHYLATOXIN_1 UniProtKB/TrEMBL
  ANAPHYLATOXIN_2 UniProtKB/TrEMBL
  NTR UniProtKB/TrEMBL
SMART A2M UniProtKB/TrEMBL
  A2M_N_2 UniProtKB/TrEMBL
  A2M_recep UniProtKB/TrEMBL
  ANATO UniProtKB/TrEMBL
  C345C UniProtKB/TrEMBL
  Thiol-ester_cl UniProtKB/TrEMBL
Superfamily-SCOP SSF47686 UniProtKB/TrEMBL
  SSF48239 UniProtKB/TrEMBL
  SSF49410 UniProtKB/TrEMBL
  SSF50242 UniProtKB/TrEMBL
UniProt A0A287A5Z8_PIG UniProtKB/TrEMBL
  A0A287B5U4_PIG UniProtKB/TrEMBL
  A0A287B8S9_PIG UniProtKB/TrEMBL
  A0A480I0T0 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V0B2 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V0T5_PIG UniProtKB/TrEMBL
  A0A4X1V1C1_PIG UniProtKB/TrEMBL
  A0A4X1V229_PIG UniProtKB/TrEMBL
  A0A5G2QAW9_PIG UniProtKB/TrEMBL
  A0A8D0JNM5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0LSD8_PIG UniProtKB/TrEMBL
  A0A8D1JDJ7 ENTREZGENE
  A0A8D1JHZ6_PIG UniProtKB/TrEMBL
  A0A8D1JKQ8_PIG UniProtKB/TrEMBL
  F1S3H9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A8D1JDJ7 UniProtKB/TrEMBL