PLXNA3 (plexin A3) - Rat Genome Database

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Gene: PLXNA3 (plexin A3) Sus scrofa
Analyze
Symbol: PLXNA3
Name: plexin A3
RGD ID: 14187694
Description: ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); semaphorin receptor activity (inferred); INVOLVED IN axon extension involved in axon guidance (ortholog); axon guidance (ortholog); hippocampus development (ortholog); ASSOCIATED WITH adrenoleukodystrophy (ortholog); autistic disorder (ortholog); Barth syndrome (ortholog); FOUND IN plasma membrane (inferred); semaphorin receptor complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: plexin-A3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,983,943 - 124,997,072 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X124,982,307 - 124,997,098 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X143,588,358 - 143,603,211 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PLXNA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,983,943 - 124,997,072 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X124,982,307 - 124,997,098 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X143,588,358 - 143,603,211 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLXNA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X154,458,281 - 154,477,779 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX154,458,281 - 154,477,779 (+)EnsemblGRCh38hg38GRCh38
GRCh37X153,686,621 - 153,706,118 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,339,817 - 153,355,179 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X153,250,326 - 153,265,688NCBI
CeleraX153,847,674 - 153,863,036 (+)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX142,263,786 - 142,279,038 (+)NCBIHuRef
CHM1_1X153,598,267 - 153,613,626 (+)NCBICHM1_1
T2T-CHM13v2.0X152,694,791 - 152,714,288 (+)NCBIT2T-CHM13v2.0
Plxna3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X73,372,644 - 73,388,295 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX73,372,672 - 73,388,295 (+)EnsemblGRCm39 Ensembl
GRCm38X74,328,290 - 74,344,689 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX74,329,066 - 74,344,689 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X71,574,405 - 71,590,028 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X70,581,819 - 70,596,483 (+)NCBIMGSCv36mm8
CeleraX65,582,855 - 65,598,478 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX38.0NCBI
Plxna3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X157,266,986 - 157,282,896 (+)NCBIGRCr8
mRatBN7.2X152,115,699 - 152,131,608 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX152,115,819 - 152,131,603 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX154,256,947 - 154,272,736 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X157,820,173 - 157,835,962 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X155,491,971 - 155,507,760 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X156,363,400 - 156,379,433 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX156,363,405 - 156,379,189 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01152,103,535 - 152,119,342 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X160,261,781 - 160,277,570 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1135,765,043 - 135,780,832 (-)NCBICelera
Cytogenetic MapXq37NCBI
Plxna3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955580957,860 - 972,772 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955580958,033 - 972,123 (+)NCBIChiLan1.0ChiLan1.0
PLXNA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X154,432,646 - 154,448,014 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X154,436,251 - 154,455,295 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X143,900,029 - 143,915,391 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X153,772,700 - 153,786,167 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX153,772,700 - 153,786,167 (+)Ensemblpanpan1.1panPan2
PLXNA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X122,165,460 - 122,180,727 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX122,167,144 - 122,180,951 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X125,307,120 - 125,321,660 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX125,306,775 - 125,321,599 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X121,076,136 - 121,090,670 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X123,591,257 - 123,605,728 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X123,352,967 - 123,367,509 (+)NCBIUU_Cfam_GSD_1.0
Plxna3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X119,471,987 - 119,488,955 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049368091,209,743 - 1,226,728 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049368091,209,787 - 1,226,726 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLXNA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X128,706,354 - 128,721,971 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX128,708,424 - 128,721,971 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606566,695,159 - 66,710,804 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plxna3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624946926,521 - 939,483 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624946924,956 - 939,483 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PLXNA3
218 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 7 3 3 5 2 23 2 3 3
Below cutoff 3 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000024845   ⟹   ENSSSCP00000027839
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX124,983,943 - 124,997,072 (+)Ensembl
RefSeq Acc Id: XM_021080740   ⟹   XP_020936399
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X124,982,307 - 124,997,098 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020936399 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000027839
  ENSSSCP00000027839.4
  ENSSSCP00025025822.1
  ENSSSCP00035025148.1
  ENSSSCP00045000173.1
  ENSSSCP00055010213.1
  ENSSSCP00065004273.1
  ENSSSCP00070010849.1
Reference Protein Sequences
RefSeq Acc Id: XP_020936399   ⟸   XM_021080740
- UniProtKB: A0A4X1T6S2 (UniProtKB/TrEMBL),   A0A8D1XDT7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000027839   ⟸   ENSSSCT00000024845
Protein Domains
Sema


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000023483 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025044813 UniProtKB/TrEMBL
  ENSSSCG00035046821 UniProtKB/TrEMBL
  ENSSSCG00045000283 UniProtKB/TrEMBL
  ENSSSCG00055006649 UniProtKB/TrEMBL
  ENSSSCG00065007616 UniProtKB/TrEMBL
  ENSSSCG00070006852 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000024845 ENTREZGENE
  ENSSSCT00000024845.4 UniProtKB/TrEMBL
  ENSSSCT00025060849.1 UniProtKB/TrEMBL
  ENSSSCT00035062280.1 UniProtKB/TrEMBL
  ENSSSCT00045000364.1 UniProtKB/TrEMBL
  ENSSSCT00055012996.1 UniProtKB/TrEMBL
  ENSSSCT00065010242.1 UniProtKB/TrEMBL
  ENSSSCT00070013169.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
  IPT_dom UniProtKB/TrEMBL
  Plexin UniProtKB/TrEMBL
  Plexin_cytoplasmic_RasGAP_dom UniProtKB/TrEMBL
  Plexin_RBD UniProtKB/TrEMBL
  Plexin_repeat UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  Semap_dom UniProtKB/TrEMBL
  Semap_dom_sf UniProtKB/TrEMBL
  TIG1_plexin UniProtKB/TrEMBL
  TIG2_plexin UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
NCBI Gene PLXNA3 ENTREZGENE
PANTHER PLEXIN-A3 UniProtKB/TrEMBL
  PTHR22625 UniProtKB/TrEMBL
Pfam Plexin_cytopl UniProtKB/TrEMBL
  Plexin_RBD UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
  TIG UniProtKB/TrEMBL
  TIG_2 UniProtKB/TrEMBL
  TIG_plexin UniProtKB/TrEMBL
PROSITE SEMA UniProtKB/TrEMBL
SMART IPT UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
Superfamily-SCOP Plexin repeat UniProtKB/TrEMBL
  SSF101912 UniProtKB/TrEMBL
  SSF48350 UniProtKB/TrEMBL
  SSF81296 UniProtKB/TrEMBL
UniProt A0A4X1T6S2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1PZW6_PIG UniProtKB/TrEMBL
  A0A8D1XDT7 ENTREZGENE, UniProtKB/TrEMBL
  I3LUN9_PIG UniProtKB/TrEMBL
VGNC ID VGNC:91581 ENTREZGENE