ARL8A (ADP ribosylation factor like GTPase 8A) - Rat Genome Database

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Gene: ARL8A (ADP ribosylation factor like GTPase 8A) Sus scrofa
Analyze
Symbol: ARL8A
Name: ADP ribosylation factor like GTPase 8A
RGD ID: 14169959
Description: ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); INVOLVED IN anterograde axonal transport (inferred); protein transport (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); familial adult myoclonic epilepsy 5 (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN axon cytoplasm (inferred); cytolytic granule membrane (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ADP-ribosylation factor-like protein 8A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1024,314,932 - 24,324,228 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11024,314,929 - 24,324,225 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21028,715,516 - 28,718,510 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ARL8A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1024,314,932 - 24,324,228 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11024,314,929 - 24,324,225 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21028,715,516 - 28,718,510 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARL8A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381202,133,404 - 202,144,737 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1202,133,404 - 202,144,743 (-)EnsemblGRCh38hg38GRCh38
GRCh371202,102,532 - 202,113,865 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361200,368,600 - 200,380,489 (-)NCBINCBI36Build 36hg18NCBI36
Build 341198,833,633 - 198,845,523NCBI
Celera1175,225,835 - 175,237,724 (-)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1173,268,070 - 173,279,422 (-)NCBIHuRef
CHM1_11203,524,823 - 203,536,155 (-)NCBICHM1_1
T2T-CHM13v2.01201,390,975 - 201,402,296 (-)NCBIT2T-CHM13v2.0
Arl8a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391135,074,572 - 135,084,007 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1135,074,562 - 135,084,007 (+)EnsemblGRCm39 Ensembl
GRCm381135,146,834 - 135,156,268 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1135,146,824 - 135,156,269 (+)EnsemblGRCm38mm10GRCm38
MGSCv371137,043,411 - 137,052,845 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361136,963,245 - 136,972,679 (+)NCBIMGSCv36mm8
Celera1137,773,693 - 137,783,013 (+)NCBICelera
Cytogenetic Map1E4NCBI
Arl8a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81349,137,632 - 49,146,633 (+)NCBIGRCr8
mRatBN7.21346,585,845 - 46,594,851 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1346,585,845 - 46,594,851 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1349,192,596 - 49,201,567 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01350,480,668 - 50,489,635 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01347,746,744 - 47,755,694 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01351,972,974 - 51,981,976 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1351,972,974 - 51,981,976 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01357,024,684 - 57,033,686 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41348,108,242 - 48,117,244 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1346,911,113 - 46,920,108 (+)NCBICelera
Cytogenetic Map13q13NCBI
Arl8a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540638,224,124 - 38,226,542 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540638,223,115 - 38,226,563 (-)NCBIChiLan1.0ChiLan1.0
ARL8A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2147,237,090 - 47,248,414 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1147,201,781 - 47,213,092 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01177,731,381 - 177,742,688 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11182,033,376 - 182,045,145 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1182,033,376 - 182,045,145 (-)Ensemblpanpan1.1panPan2
ARL8A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.17875,679 - 877,184 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha7922,825 - 931,231 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.07878,512 - 887,030 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.17866,867 - 875,258 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.07975,161 - 983,495 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.07999,160 - 1,007,493 (+)NCBIUU_Cfam_GSD_1.0
Arl8a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934473,160,437 - 73,170,294 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365672,395,111 - 2,404,972 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365672,395,098 - 2,404,974 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARL8A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12527,261,506 - 27,272,477 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2527,261,562 - 27,271,416 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605528,041,575 - 28,052,548 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arl8a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248078,593,619 - 8,602,647 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248078,594,097 - 8,602,640 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ARL8A
226 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1 21
Low 10 4 2 4 2 2 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000038003   ⟹   ENSSSCP00000037990
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1024,314,932 - 24,324,228 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000081596   ⟹   ENSSSCP00000067103
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1024,314,932 - 24,324,228 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000097973   ⟹   ENSSSCP00000078715
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1024,316,302 - 24,324,228 (-)Ensembl
RefSeq Acc Id: XM_021064533   ⟹   XP_020920192
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11024,314,929 - 24,324,225 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020920192   ⟸   XM_021064533
- UniProtKB: A0A287A2L0 (UniProtKB/TrEMBL),   A0A4X1SDU0 (UniProtKB/TrEMBL),   A0A8W4FAY4 (UniProtKB/TrEMBL),   A0A8W4FPI3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000067103   ⟸   ENSSSCT00000081596
RefSeq Acc Id: ENSSSCP00000037990   ⟸   ENSSSCT00000038003
RefSeq Acc Id: ENSSSCP00000078715   ⟸   ENSSSCT00000097973


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011535 UniProtKB/TrEMBL
  ENSSSCG00000036967 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00030038502 UniProtKB/TrEMBL
  ENSSSCG00035048017 UniProtKB/TrEMBL
  ENSSSCG00040044144 UniProtKB/TrEMBL
  ENSSSCG00045017543 UniProtKB/TrEMBL
  ENSSSCG00050079043 UniProtKB/TrEMBL
  ENSSSCG00055016287 UniProtKB/TrEMBL
  ENSSSCG00060046500 UniProtKB/TrEMBL
  ENSSSCG00065053072 UniProtKB/TrEMBL
  ENSSSCG00070000218 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000038003 ENTREZGENE
  ENSSSCT00000038003.3 UniProtKB/TrEMBL
  ENSSSCT00000081596.2 UniProtKB/TrEMBL
  ENSSSCT00000097973.1 UniProtKB/TrEMBL
  ENSSSCT00000101511.1 UniProtKB/TrEMBL
  ENSSSCT00000101580.1 UniProtKB/TrEMBL
  ENSSSCT00030053617.1 UniProtKB/TrEMBL
  ENSSSCT00035063955.1 UniProtKB/TrEMBL
  ENSSSCT00035063957.1 UniProtKB/TrEMBL
  ENSSSCT00040059182.1 UniProtKB/TrEMBL
  ENSSSCT00040059283.1 UniProtKB/TrEMBL
  ENSSSCT00045029887.1 UniProtKB/TrEMBL
  ENSSSCT00045029967.1 UniProtKB/TrEMBL
  ENSSSCT00050109132.1 UniProtKB/TrEMBL
  ENSSSCT00055032216.1 UniProtKB/TrEMBL
  ENSSSCT00060063125.1 UniProtKB/TrEMBL
  ENSSSCT00065072678.1 UniProtKB/TrEMBL
  ENSSSCT00065072700.1 UniProtKB/TrEMBL
  ENSSSCT00070000401.1 UniProtKB/TrEMBL
  ENSSSCT00070000408.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro Arl8a/8b UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase_ARF/SAR UniProtKB/TrEMBL
NCBI Gene ARL8A ENTREZGENE
PANTHER ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 UniProtKB/TrEMBL
  ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8A UniProtKB/TrEMBL
  ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8B UniProtKB/TrEMBL
Pfam Arf UniProtKB/TrEMBL
PRINTS SAR1GTPBP UniProtKB/TrEMBL
PROSITE ARF UniProtKB/TrEMBL
  RAB UniProtKB/TrEMBL
  SAR1 UniProtKB/TrEMBL
SMART ARF UniProtKB/TrEMBL
  RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  SAR UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A287A2L0 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SDU0 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SDX0_PIG UniProtKB/TrEMBL
  A0A5G2QYT5_PIG UniProtKB/TrEMBL
  A0A8W4FAY4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FK82_PIG UniProtKB/TrEMBL
  A0A8W4FPI3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:96067 ENTREZGENE