TMEM62 (transmembrane protein 62) - Rat Genome Database

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Gene: TMEM62 (transmembrane protein 62) Sus scrofa
Analyze
Symbol: TMEM62
Name: transmembrane protein 62
RGD ID: 14146652
Description: ENCODES a protein that exhibits hydrolase activity (inferred); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); FOUND IN membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1128,269,599 - 128,306,056 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11128,269,590 - 128,306,128 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21143,085,560 - 143,102,893 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
TMEM62
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1128,269,599 - 128,306,056 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11128,269,590 - 128,306,128 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21143,085,560 - 143,102,893 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM62
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381543,133,115 - 43,185,144 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1543,123,279 - 43,185,144 (+)EnsemblGRCh38hg38GRCh38
GRCh371543,425,313 - 43,477,342 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361541,213,014 - 41,264,634 (+)NCBINCBI36Build 36hg18NCBI36
Celera1520,196,546 - 20,248,167 (+)NCBICelera
Cytogenetic Map15q15.2NCBI
HuRef1520,273,823 - 20,326,137 (+)NCBIHuRef
CHM1_11543,544,545 - 43,596,164 (+)NCBICHM1_1
T2T-CHM13v2.01540,940,411 - 40,992,433 (+)NCBIT2T-CHM13v2.0
Tmem62
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392120,806,959 - 120,838,333 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2120,807,498 - 120,838,333 (+)EnsemblGRCm39 Ensembl
GRCm382120,976,478 - 121,007,849 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2120,977,017 - 121,007,852 (+)EnsemblGRCm38mm10GRCm38
MGSCv372120,802,798 - 120,833,579 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362120,668,503 - 120,699,284 (+)NCBIMGSCv36mm8
Celera2122,126,497 - 122,157,454 (+)NCBICelera
Cytogenetic Map2E5NCBI
cM Map260.37NCBI
Tmem62
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83128,380,366 - 128,415,583 (+)NCBIGRCr8
mRatBN7.23107,921,940 - 107,961,830 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3107,927,307 - 107,961,795 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3111,601,610 - 111,635,771 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03120,197,172 - 120,231,349 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03117,857,561 - 117,891,753 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03112,915,415 - 112,950,418 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3112,916,217 - 112,949,728 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03119,459,008 - 119,493,453 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43107,752,430 - 107,786,727 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13107,649,217 - 107,682,580 (+)NCBI
Celera3106,832,043 - 106,866,765 (+)NCBICelera
Cytogenetic Map3q35NCBI
Tmem62
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554169,737,616 - 9,772,738 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554169,731,871 - 9,772,738 (+)NCBIChiLan1.0ChiLan1.0
TMEM62
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21632,381,858 - 32,436,848 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11536,543,655 - 36,598,638 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01522,091,408 - 22,146,419 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11540,248,948 - 40,301,280 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1540,248,952 - 40,301,280 (+)Ensemblpanpan1.1panPan2
TMEM62
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13010,007,112 - 10,053,501 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3010,021,868 - 10,052,992 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3010,065,964 - 10,112,867 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03010,142,626 - 10,189,946 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3010,158,041 - 10,189,940 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13010,059,859 - 10,106,766 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03010,180,840 - 10,227,743 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03010,300,533 - 10,347,490 (+)NCBIUU_Cfam_GSD_1.0
Tmem62
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864088,475,190 - 88,517,054 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364716,323,531 - 6,364,679 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364716,323,196 - 6,365,111 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM62
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12639,808,067 - 39,851,865 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2639,807,923 - 39,851,611 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048101,157,986 - 101,205,090 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem62
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480410,225,414 - 10,287,773 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480410,225,724 - 10,287,773 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TMEM62
754 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3 3 2 4 1 3 1
Low 7 4 3 2 19 1 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000005208   ⟹   ENSSSCP00000005082
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1128,269,606 - 128,306,056 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000023322   ⟹   ENSSSCP00000021800
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1128,269,606 - 128,306,056 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000061188   ⟹   ENSSSCP00000032103
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1128,269,599 - 128,305,831 (-)Ensembl
RefSeq Acc Id: XM_021097051   ⟹   XP_020952710
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11128,269,590 - 128,306,119 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021097060   ⟹   XP_020952719
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11128,269,593 - 128,306,128 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021097069   ⟹   XP_020952728
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11128,269,593 - 128,305,729 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021097078   ⟹   XP_020952737
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11128,269,593 - 128,303,781 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020952710   ⟸   XM_021097051
- Peptide Label: isoform X1
- UniProtKB: A0A4X1V1J6 (UniProtKB/TrEMBL),   F1SI46 (UniProtKB/TrEMBL),   A0A8D0Z8V6 (UniProtKB/TrEMBL),   A0A8D1GWV9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020952719   ⟸   XM_021097060
- Peptide Label: isoform X2
- UniProtKB: A0A4X1V705 (UniProtKB/TrEMBL),   A0A286ZKL6 (UniProtKB/TrEMBL),   A0A8D0Z5E5 (UniProtKB/TrEMBL),   A0A8D1GPQ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020952728   ⟸   XM_021097069
- Peptide Label: isoform X3
- UniProtKB: A0A8D0LPF1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020952737   ⟸   XM_021097078
- Peptide Label: isoform X4
- UniProtKB: A0A8D2BHI4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000005082   ⟸   ENSSSCT00000005208
RefSeq Acc Id: ENSSSCP00000032103   ⟸   ENSSSCT00000061188
RefSeq Acc Id: ENSSSCP00000021800   ⟸   ENSSSCT00000023322
Protein Domains
Calcineurin-like phosphoesterase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000004716 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005024020 UniProtKB/TrEMBL
  ENSSSCG00015079251 UniProtKB/TrEMBL
  ENSSSCG00025076591 UniProtKB/TrEMBL
  ENSSSCG00030062921 UniProtKB/TrEMBL
  ENSSSCG00035023143 UniProtKB/TrEMBL
  ENSSSCG00040027647 UniProtKB/TrEMBL
  ENSSSCG00045005906 UniProtKB/TrEMBL
  ENSSSCG00050050408 UniProtKB/TrEMBL
  ENSSSCG00055016449 UniProtKB/TrEMBL
  ENSSSCG00060033885 UniProtKB/TrEMBL
  ENSSSCG00065048990 UniProtKB/TrEMBL
  ENSSSCG00070021825 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000005208 ENTREZGENE
  ENSSSCT00000005208.3 UniProtKB/TrEMBL
  ENSSSCT00000023322.3 UniProtKB/TrEMBL
  ENSSSCT00000061188 ENTREZGENE
  ENSSSCT00000061188.3 UniProtKB/TrEMBL
  ENSSSCT00005038459.1 UniProtKB/TrEMBL
  ENSSSCT00015107625.1 UniProtKB/TrEMBL
  ENSSSCT00015107639.1 UniProtKB/TrEMBL
  ENSSSCT00015107668.1 UniProtKB/TrEMBL
  ENSSSCT00025106135.1 UniProtKB/TrEMBL
  ENSSSCT00025106167.1 UniProtKB/TrEMBL
  ENSSSCT00025106181.1 UniProtKB/TrEMBL
  ENSSSCT00030088107.1 UniProtKB/TrEMBL
  ENSSSCT00030088117.1 UniProtKB/TrEMBL
  ENSSSCT00030088139.1 UniProtKB/TrEMBL
  ENSSSCT00035030313.1 UniProtKB/TrEMBL
  ENSSSCT00035030317.1 UniProtKB/TrEMBL
  ENSSSCT00035030322.1 UniProtKB/TrEMBL
  ENSSSCT00040037201.1 UniProtKB/TrEMBL
  ENSSSCT00040037271.1 UniProtKB/TrEMBL
  ENSSSCT00040037360.1 UniProtKB/TrEMBL
  ENSSSCT00045009824.1 UniProtKB/TrEMBL
  ENSSSCT00045009845.1 UniProtKB/TrEMBL
  ENSSSCT00045009854.1 UniProtKB/TrEMBL
  ENSSSCT00050068603.1 UniProtKB/TrEMBL
  ENSSSCT00050068611.1 UniProtKB/TrEMBL
  ENSSSCT00050068632.1 UniProtKB/TrEMBL
  ENSSSCT00055032721.1 UniProtKB/TrEMBL
  ENSSSCT00055032765.1 UniProtKB/TrEMBL
  ENSSSCT00055032836.1 UniProtKB/TrEMBL
  ENSSSCT00060045955.1 UniProtKB/TrEMBL
  ENSSSCT00065067038.1 UniProtKB/TrEMBL
  ENSSSCT00065067052.1 UniProtKB/TrEMBL
  ENSSSCT00065067057.1 UniProtKB/TrEMBL
  ENSSSCT00070043431.1 UniProtKB/TrEMBL
  ENSSSCT00070043434.1 UniProtKB/TrEMBL
  ENSSSCT00070043440.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.21.10 UniProtKB/TrEMBL
InterPro Calcineurin-like_PHP_ApaH UniProtKB/TrEMBL
  Metallo-depent_PP-like UniProtKB/TrEMBL
  MPP_TMEM62 UniProtKB/TrEMBL
NCBI Gene TMEM62 ENTREZGENE
PANTHER HELICASE RELATED UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 62 UniProtKB/TrEMBL
Pfam Metallophos UniProtKB/TrEMBL
Superfamily-SCOP SSF56300 UniProtKB/TrEMBL
UniProt A0A286ZKL6 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V1J6 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V4P7_PIG UniProtKB/TrEMBL
  A0A4X1V705 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0LPF1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Z2Q1_PIG UniProtKB/TrEMBL
  A0A8D0Z5E5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Z8V6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1GPQ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1GPS7_PIG UniProtKB/TrEMBL
  A0A8D1GWV9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D2BHI4 ENTREZGENE, UniProtKB/TrEMBL
  F1SI46 ENTREZGENE, UniProtKB/TrEMBL
  I3LCM5_PIG UniProtKB/TrEMBL
VGNC ID VGNC:94196 ENTREZGENE