IL17RC (interleukin 17 receptor C)

Gene: IL17RC (interleukin 17 receptor C) Sus scrofa

Analyze

Symbol:

IL17RC

Name:

interleukin 17 receptor C

RGD ID:

14122990

Description:

ENCODES a protein that exhibits coreceptor activity (ortholog); interleukin-17 receptor activity (ortholog); signaling receptor binding (ortholog); INVOLVED IN defense response to fungus (ortholog); granulocyte chemotaxis (ortholog); interleukin-17A-mediated signaling pathway (ortholog); ASSOCIATED WITH Atrioventricular Septal Defect 2 (ortholog); Candidiasis, Familial, 9 (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cell surface (ortholog); plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

IL17RC_tv1; interleukin-17 receptor C

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	13	66,179,298 - 66,194,750 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	73,254,652 - 73,270,469 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Atrioventricular Septal Defect 2 (ISO)

Candidiasis, Familial, 9 (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

long QT syndrome (ISO)

Neurodevelopmental Disorders (ISO)

Prostatic Neoplasms (ISO)

severe congenital neutropenia 6 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

defense response to fungus (ISO)

granulocyte chemotaxis (ISO)

interleukin-17A-mediated signaling pathway (ISO)

positive regulation of cytokine production involved in inflammatory response (ISO)

positive regulation of interleukin-6 production (ISO)

Cellular Component

cell surface (ISO)

plasma membrane (ISO)

Molecular Function

coreceptor activity (ISO)

interleukin-17 receptor activity (ISO)

protein binding (ISO)

signaling receptor binding (ISO)

References

Additional References at PubMed

PMID:14681463	PMID:17145712	PMID:30032202

Genomics

Comparative Map Data

IL17RC
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	13	66,179,298 - 66,194,750 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	73,254,652 - 73,270,469 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IL17RC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	9,917,098 - 9,933,621 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	9,917,074 - 9,933,630 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	9,958,782 - 9,975,305 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	9,933,782 - 9,950,314 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	3	9,894,245 - 9,910,766 (+)	NCBI		Celera
Cytogenetic Map	3	p25.3	NCBI
HuRef	3	9,895,102 - 9,911,628 (+)	NCBI		HuRef
CHM1_1	3	9,908,906 - 9,925,428 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	9,909,121 - 9,925,611 (+)	NCBI		T2T-CHM13v2.0

Il17rc
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	113,448,416 - 113,460,124 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	113,448,388 - 113,460,101 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	113,471,455 - 113,483,163 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	113,471,427 - 113,483,140 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	113,421,449 - 113,433,132 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	113,437,351 - 113,448,915 (+)	NCBI		MGSCv36	mm8
Celera	6	115,298,416 - 115,310,099 (+)	NCBI		Celera
Cytogenetic Map	6	E3	NCBI
cM Map	6	52.77	NCBI

Il17rc
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	148,174,573 - 148,187,071 (+)	NCBI		GRCr8
mRatBN7.2	4	146,618,321 - 146,631,444 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	146,619,004 - 146,631,442 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	152,002,952 - 152,015,394 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	147,783,795 - 147,796,235 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	146,406,105 - 146,418,521 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	145,426,647 - 145,439,845 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	145,427,367 - 145,439,843 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	208,724,714 - 208,737,144 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	149,362,504 - 149,374,934 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	149,608,503 - 149,619,775 (+)	NCBI
Celera	4	135,174,928 - 135,187,360 (+)	NCBI		Celera
Cytogenetic Map	4	q42	NCBI

Il17rc
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955561	1,410,941 - 1,423,023 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955561	1,410,100 - 1,423,041 (+)	NCBI	ChiLan1.0	ChiLan1.0

IL17RC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	9,920,929 - 9,937,679 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	9,925,695 - 9,942,438 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	9,861,423 - 9,878,154 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	10,210,241 - 10,226,796 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	10,210,241 - 10,226,796 (+)	Ensembl	panpan1.1		panPan2

IL17RC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	8,342,622 - 8,355,996 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	8,334,345 - 8,355,387 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	8,376,296 - 8,390,079 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	8,371,888 - 8,385,638 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	8,371,888 - 8,384,687 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	8,094,198 - 8,107,969 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	8,439,708 - 8,453,451 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	8,412,789 - 8,426,541 (-)	NCBI		UU_Cfam_GSD_1.0

Il17rc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404942	15,627,696 - 15,642,317 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936602	3,267,425 - 3,282,040 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936602	3,267,397 - 3,281,985 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IL17RC
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	45,944,385 - 45,960,188 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	45,944,669 - 45,960,164 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	120,602,953 - 120,618,740 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Il17rc
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624731	4,525,556 - 4,536,858 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624731	4,524,090 - 4,536,879 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in IL17RC
285 total Variants

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021069809	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK347630	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK396665	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU464019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GACC01000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01007212	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_021069809 ⟹ XP_020925468

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	13	66,179,298 - 66,194,750 (+)	NCBI

Sequence:

show sequence

ATGCCTGTGCCCTGGTTCCTTCTGTCCTTGGCACTGGGCCGAAACCCTGTGGTCCTCTCTCTAG
AGAGGTTTGGGGCTCAGGACGCTGCCCGCTGCTCTCCGACAGAACTGGTGCTAAGGTGCCACAA
GGAGACCGACTGCGACCTCTGTGTGCGTGTGGCTGTCCACTTGGCTGTGCATGCACTGGGCTTC
TTGGAAGGAAGCCAAAGCCAGAGCGGCCTCTCTCAGGCCCATGTGGTGCTGTCCTTCCAGGCCT
ACCCTACTGCCCGCTGCGTCCTGCTGGAGGTGCAAATAGAGAAGCTGAGGCTTGTAGAGGAAAG
TCTGTGGCTGGATCCACGTCTGGCGGACTTCCTGCACATCATGTCTGTCCCACATGACACTGTG
GAAGCGGCCCTGCCCTGGCTCAACGTGTCTGCTGATGGCGACCATGTGCGCCTTGTGCTGGACG
TCTCTGAGGAACAGCGCTTCGGCCTCTCCCTGTACTGGAACCAGACCCAGGGCCCTGCAAAACC
CTGGTGGCACAGAAACCTGACTGGGCCACAGACCATTACCTTGAACCACACAGACCTGGTTCCC
TGCCTCTGTATTCAGGACTCCTACCTGTGCTTCGTGCCCTCTTCAGATGTCATCGCCCCCTTGA
AGACCCTCGCGCACACAGGAACTCTGGCGTGCAGCCCGGTTGCAGCTGCTGCCTTCGCAGGACT
GGCGGCTGGATGCGCCGTGCTCCCTGCCCGCCGAGGCCACGCTGTGCTGGCAGGCACAGGATGG
GGGCCCTGCCAGCCGCTGGTTCCGCCGCTGCCCCGAGCAAATGTCACCGTGAATGTGAGCACCT
GGGAGAAGCTGCAGCTTCAAGAGTGCCTGTGGACTGACTCCCTGGGGCCCCTCAAGGATGACAT
GCTGGTGGTGGAGACAAGAGATTCCCAGGACAACAGATCACTCTGTGCCTTGGAACCCAGTGGC
TGCACCCCACTGCTCAGCAGAGCTTCCACGCGGCTGCCGCCAGGAGCCGAGTGGCTTTGCTCCT
CTACTCCCCGACGACGCAGGCTTCGAGCGCCTCGTGGCGCCCTGGCGTCAGCGCTGTGTCAGCT
GCCGCTGCGCGTGGCCGTGGACCTGTGGAGCCGCCGCGAACTGAGCGCACAGGGGCCCCTGGCC
TGGTTCCACGCGCAGCGGCGCCAGACCCTCCAGGAAGGCGGCGTGGTGGTCCTGCTCTTCTCGC
CAGGGGCCGTGGCCATGTGCCACGAGTGGCTGCAGGATGCGGCGTCAGCGCCCGGGGCACACGG
CCCGCACGACGCCTTCACCGCCTCGCTCAGCTGCGTGCTGCCAGACTTCTTGCAGGGCCGGGCA
CCCGGCCGCTACATCGGGGCCTACTTCGACAGACTGCTGCCCCCGGACGCCGTGCCCGCCCTGT
TCCGCAGCGTGCCGGTCTTCTCACTGCCCTCACAGCTGCCCGACTTCCTGGGACCCTACAGGGG
CCCGGCGCCCTCCGCTCGAGGCGGCTCGCGGAGAGAGCGGATCAAGTGTCCCGGGCCCTGCAGC
CCGCCCTGGACAGCTGCTTCTGCGGCAAATCAGGACTGCCGCGCTCAACCGGTATCCCCGCGGC
CCTTTAACAACCCCGACAGGTGCAGCCCGTAG

hide sequence

Protein Sequences


Protein RefSeqs	XP_020925468	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	JAA53788	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_020925468 ⟸ XM_021069809

- Sequence:

show sequence

MPVPWFLLSLALGRNPVVLSLERFGAQDAARCSPTELVLRCHKETDCDLCVRVAVHLAVHALGF
LEGSQSQSGLSQAHVVLSFQAYPTARCVLLEVQIEKLRLVEESLWLDPRLADFLHIMSVPHDTV
EAALPWLNVSADGDHVRLVLDVSEEQRFGLSLYWNQTQGPAKPWWHRNLTGPQTITLNHTDLVP
CLCIQDSYLCFVPSSDVIAPLKTLAHTGTLACSPVAAAAFAGLAAGCAVLPARRGHAVLAGTGW
GPCQPLVPPLPRANVTVNVSTWEKLQLQECLWTDSLGPLKDDMLVVETRDSQDNRSLCALEPSG
CTPLLSRASTRLPPGAEWLCSSTPRRRRLRAPRGALASALCQLPLRVAVDLWSRRELSAQGPLA
WFHAQRRQTLQEGGVVVLLFSPGAVAMCHEWLQDAASAPGAHGPHDAFTASLSCVLPDFLQGRA
PGRYIGAYFDRLLPPDAVPALFRSVPVFSLPSQLPDFLGPYRGPAPSARGGSRRERIKCPGPCS
PPWTAASAANQDCRAQPVSPRPFNNPDRCSP

hide sequence

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	IL17RC	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - OMIM