RSPH3 (radial spoke head 3) - Rat Genome Database

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Gene: RSPH3 (radial spoke head 3) Sus scrofa
Analyze
Symbol: RSPH3
Name: radial spoke head 3
RGD ID: 14089281
Description: ASSOCIATED WITH 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (ortholog); chromosome 6q24-q25 deletion syndrome (ortholog); genetic disease (ortholog); FOUND IN cilium (inferred); cytoplasm (inferred); cytoskeleton (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: radial spoke 3 homolog; radial spoke head 3 homolog; radial spoke head protein 3 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl18,244,040 - 8,265,659 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.118,243,177 - 8,265,816 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2110,141,811 - 10,149,319 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cilium  (IBA,IEA)
cytoplasm  (IEA)
cytoskeleton  (IEA)
motile cilium  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:30032202  


Genomics

Comparative Map Data
RSPH3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl18,244,040 - 8,265,659 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.118,243,177 - 8,265,816 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2110,141,811 - 10,149,319 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RSPH3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386158,962,980 - 159,000,202 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6158,972,871 - 159,000,202 (-)EnsemblGRCh38hg38GRCh38
GRCh376159,393,903 - 159,421,234 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366159,318,254 - 159,341,186 (-)NCBINCBI36Build 36hg18NCBI36
Build 346159,368,676 - 159,391,607NCBI
Celera6160,046,571 - 160,069,312 (-)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6156,868,976 - 156,891,903 (-)NCBIHuRef
CHM1_16159,660,720 - 159,683,640 (-)NCBICHM1_1
T2T-CHM13v2.06160,212,959 - 160,245,813 (-)NCBIT2T-CHM13v2.0
Rsph3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39178,164,446 - 8,198,388 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl178,164,446 - 8,198,656 (+)EnsemblGRCm39 Ensembl
GRCm38177,945,614 - 7,979,556 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl177,945,614 - 7,979,824 (+)EnsemblGRCm38mm10GRCm38
MGSCv37178,138,479 - 8,172,421 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36177,784,157 - 7,817,660 (+)NCBIMGSCv36mm8
Celera177,474,283 - 7,474,984 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map174.82NCBI
Rsph3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8149,506,988 - 49,565,740 (-)NCBIGRCr8
mRatBN7.2147,101,961 - 47,155,201 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl147,101,961 - 47,154,232 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx147,665,045 - 47,703,111 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0153,652,529 - 53,690,574 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0147,740,516 - 47,778,582 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0147,412,151 - 47,478,924 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,426,258 - 47,477,524 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0148,729,556 - 48,780,832 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4141,313,530 - 41,336,537 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1141,316,470 - 41,370,068 (-)NCBI
Celera142,782,009 - 42,842,838 (-)NCBICelera
Cytogenetic Map1q11NCBI
Rsph3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554393,509,395 - 3,534,392 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554393,510,076 - 3,533,924 (+)NCBIChiLan1.0ChiLan1.0
RSPH3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25178,993,081 - 179,105,295 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16176,898,056 - 177,010,374 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06156,861,740 - 156,889,821 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16161,875,729 - 161,904,276 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6161,880,465 - 161,904,315 (-)Ensemblpanpan1.1panPan2
RSPH3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1148,329,171 - 48,349,924 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl148,329,211 - 48,349,088 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha149,171,625 - 49,192,001 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0148,513,493 - 48,534,673 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl148,513,534 - 48,534,213 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1148,389,455 - 48,409,743 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0148,260,340 - 48,280,628 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0148,819,818 - 48,840,110 (-)NCBIUU_Cfam_GSD_1.0
Rsph3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946143,313,711 - 143,341,249 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648910,569,541 - 10,593,100 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648910,568,736 - 10,592,912 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RSPH3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11386,562,453 - 86,582,483 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604058,957,000 - 58,976,458 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rsph3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624929661,495 - 682,072 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624929661,257 - 682,772 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RSPH3
1195 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 7 2 3 4 1 19 2 3 2
Below cutoff 3 2 1 1 4 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000004483   ⟹   ENSSSCP00000004381
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl18,244,040 - 8,265,659 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000060453   ⟹   ENSSSCP00000035240
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl18,244,040 - 8,265,659 (+)Ensembl
RefSeq Acc Id: XM_001926970   ⟹   XP_001927005
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.118,243,177 - 8,265,816 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_001927005 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000004381.4
  ENSSSCP00000035240.2
  ENSSSCP00045023362.1
Reference Protein Sequences
RefSeq Acc Id: XP_001927005   ⟸   XM_001926970
- UniProtKB: A0A8D1KZK8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000035240   ⟸   ENSSSCT00000060453
RefSeq Acc Id: ENSSSCP00000004381   ⟸   ENSSSCT00000004483


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000004055 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00045019692 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000004483.4 UniProtKB/TrEMBL
  ENSSSCT00000060453.2 UniProtKB/TrEMBL
  ENSSSCT00045033694.1 UniProtKB/TrEMBL
InterPro Radial_spoke_3 UniProtKB/TrEMBL
NCBI Gene RSPH3 ENTREZGENE
PANTHER PTHR21648 UniProtKB/TrEMBL
  RADIAL SPOKE HEAD PROTEIN 3 HOMOLOG UniProtKB/TrEMBL
Pfam Radial_spoke_3 UniProtKB/TrEMBL
UniProt A0A286ZUA2_PIG UniProtKB/TrEMBL
  A0A8D1KZK8 ENTREZGENE, UniProtKB/TrEMBL
  F1SB46_PIG UniProtKB/TrEMBL
VGNC ID VGNC:103168 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-26 RSPH3  radial spoke head 3    radial spoke head 3 homolog  Symbol and/or name change 5135510 APPROVED