CD109 (CD109 molecule) - Rat Genome Database

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Gene: CD109 (CD109 molecule) Sus scrofa
Analyze
Symbol: CD109
Name: CD109 molecule
RGD ID: 14086823
Description: ENCODES a protein that exhibits endopeptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); transforming growth factor beta binding (inferred); INVOLVED IN hair follicle development (ortholog); keratinocyte proliferation (ortholog); negative regulation of keratinocyte proliferation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Neoplasms (ortholog); High Myopia (ortholog); FOUND IN cytosol (inferred); extracellular region (inferred); extracellular space (inferred); INTERACTS WITH deoxynivalenol; ethanol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CD109 antigen
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl192,054,821 - 92,286,730 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1192,081,675 - 92,241,079 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21103,135,603 - 103,292,354 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
deoxynivalenol  (EXP)
ethanol  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CD109
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl192,054,821 - 92,286,730 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1192,081,675 - 92,241,079 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21103,135,603 - 103,292,354 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD109
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38673,679,192 - 73,828,313 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl673,695,785 - 73,828,316 (+)EnsemblGRCh38hg38GRCh38
GRCh37674,405,926 - 74,538,037 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36674,462,235 - 74,594,761 (+)NCBINCBI36Build 36hg18NCBI36
Build 34674,462,547 - 74,591,509NCBI
Celera674,800,739 - 74,932,977 (+)NCBICelera
Cytogenetic Map6q13NCBI
HuRef671,605,012 - 71,737,517 (+)NCBIHuRef
CHM1_1674,571,928 - 74,704,279 (+)NCBICHM1_1
T2T-CHM13v2.0674,857,189 - 75,006,336 (+)NCBIT2T-CHM13v2.0
Cd109
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39978,522,828 - 78,623,542 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl978,522,828 - 78,623,535 (+)EnsemblGRCm39 Ensembl
GRCm38978,615,546 - 78,716,260 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl978,615,546 - 78,716,253 (+)EnsemblGRCm38mm10GRCm38
MGSCv37978,463,353 - 78,564,067 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36978,401,461 - 78,501,937 (+)NCBIMGSCv36mm8
Celera975,790,926 - 75,891,369 (+)NCBICelera
Cytogenetic Map9E1NCBI
cM Map943.65NCBI
Cd109
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8888,334,736 - 88,449,463 (+)NCBIGRCr8
mRatBN7.2879,454,480 - 79,569,195 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl879,454,480 - 79,569,194 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx884,984,275 - 85,092,412 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0883,261,419 - 83,369,553 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0881,084,098 - 81,192,223 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0885,951,420 - 86,065,411 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl885,951,191 - 86,065,409 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0885,500,667 - 85,615,070 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4883,576,559 - 83,672,664 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1883,578,579 - 83,692,225 (+)NCBI
Celera879,200,276 - 79,310,457 (+)NCBICelera
Cytogenetic Map8q31NCBI
Cd109
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554889,281,661 - 9,378,490 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554889,281,407 - 9,378,354 (-)NCBIChiLan1.0ChiLan1.0
CD109
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2593,722,849 - 93,859,415 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1691,574,608 - 91,734,821 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0671,519,293 - 71,654,300 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1674,801,384 - 74,937,414 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl674,801,384 - 74,937,414 (+)Ensemblpanpan1.1panPan2
CD109
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11235,712,589 - 35,839,153 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1235,712,271 - 35,839,044 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1235,583,900 - 35,710,288 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01236,269,369 - 36,395,815 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1236,268,808 - 36,395,710 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11235,808,332 - 35,938,613 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01235,830,291 - 35,960,639 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01235,954,644 - 36,085,062 (+)NCBIUU_Cfam_GSD_1.0
Cd109
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494671,014,831 - 71,146,089 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936859484,923 - 595,316 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936859467,958 - 595,337 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD109
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1171,322,681 - 1,461,945 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl171,324,105 - 1,416,491 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660587,225,201 - 7,365,431 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd109
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624819862,194 - 1,009,755 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624819861,095 - 1,013,674 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CD109
3772 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 2 2
Low 8 4 3 5 2 23 1 1
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000004956   ⟹   ENSSSCP00000004839
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl192,081,691 - 92,240,700 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000035127   ⟹   ENSSSCP00000029634
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl192,054,821 - 92,240,700 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000035901   ⟹   ENSSSCP00000028508
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl192,081,691 - 92,240,700 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000066498   ⟹   ENSSSCP00000071720
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl192,081,691 - 92,240,700 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000068892   ⟹   ENSSSCP00000060853
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl192,081,682 - 92,286,730 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000080465   ⟹   ENSSSCP00000060297
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl192,081,691 - 92,240,700 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000084275   ⟹   ENSSSCP00000064479
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl192,081,691 - 92,240,700 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000094194   ⟹   ENSSSCP00000077383
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl192,081,682 - 92,204,310 (-)Ensembl
RefSeq Acc Id: XM_001927545   ⟹   XP_001927580
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1192,081,675 - 92,241,079 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021092387   ⟹   XP_020948046
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1192,081,675 - 92,199,127 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_001927580   ⟸   XM_001927545
- Peptide Label: isoform X1
- UniProtKB: K7GKY0 (UniProtKB/TrEMBL),   A0A8D1AXL6 (UniProtKB/TrEMBL),   A0A4X1TYA4 (UniProtKB/TrEMBL),   A0A8D0XU23 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020948046   ⟸   XM_021092387
- Peptide Label: isoform X2
- UniProtKB: F1RQH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000060853   ⟸   ENSSSCT00000068892
RefSeq Acc Id: ENSSSCP00000029634   ⟸   ENSSSCT00000035127
RefSeq Acc Id: ENSSSCP00000064479   ⟸   ENSSSCT00000084275
RefSeq Acc Id: ENSSSCP00000028508   ⟸   ENSSSCT00000035901
RefSeq Acc Id: ENSSSCP00000060297   ⟸   ENSSSCT00000080465
RefSeq Acc Id: ENSSSCP00000071720   ⟸   ENSSSCT00000066498
RefSeq Acc Id: ENSSSCP00000004839   ⟸   ENSSSCT00000004956
RefSeq Acc Id: ENSSSCP00000077383   ⟸   ENSSSCT00000094194
Protein Domains
Alpha-2-macroglobulin   Alpha-2-macroglobulin bait region   Alpha-macroglobulin receptor-binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000004485 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005006616 UniProtKB/TrEMBL
  ENSSSCG00025024823 UniProtKB/TrEMBL
  ENSSSCG00030062486 UniProtKB/TrEMBL
  ENSSSCG00035071766 UniProtKB/TrEMBL
  ENSSSCG00040007452 UniProtKB/TrEMBL
  ENSSSCG00045027330 UniProtKB/TrEMBL
  ENSSSCG00060025117 UniProtKB/TrEMBL
  ENSSSCG00070013603 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000004956.5 UniProtKB/TrEMBL
  ENSSSCT00000035127.4 UniProtKB/TrEMBL
  ENSSSCT00000035901 ENTREZGENE
  ENSSSCT00000035901.3 UniProtKB/TrEMBL
  ENSSSCT00000066498.1 UniProtKB/TrEMBL
  ENSSSCT00000068892.2 UniProtKB/TrEMBL
  ENSSSCT00000080465.1 UniProtKB/TrEMBL
  ENSSSCT00000084275.1 UniProtKB/TrEMBL
  ENSSSCT00000094194 ENTREZGENE
  ENSSSCT00000094194.1 UniProtKB/TrEMBL
  ENSSSCT00005010008.1 UniProtKB/TrEMBL
  ENSSSCT00005010768.1 UniProtKB/TrEMBL
  ENSSSCT00005011062.1 UniProtKB/TrEMBL
  ENSSSCT00005011102.1 UniProtKB/TrEMBL
  ENSSSCT00005011183.1 UniProtKB/TrEMBL
  ENSSSCT00025033615.1 UniProtKB/TrEMBL
  ENSSSCT00025034294.1 UniProtKB/TrEMBL
  ENSSSCT00025034665.1 UniProtKB/TrEMBL
  ENSSSCT00025035468.1 UniProtKB/TrEMBL
  ENSSSCT00030087434.1 UniProtKB/TrEMBL
  ENSSSCT00030087483.1 UniProtKB/TrEMBL
  ENSSSCT00030087519.1 UniProtKB/TrEMBL
  ENSSSCT00030087532.1 UniProtKB/TrEMBL
  ENSSSCT00030087545.1 UniProtKB/TrEMBL
  ENSSSCT00035097070.1 UniProtKB/TrEMBL
  ENSSSCT00035097108.1 UniProtKB/TrEMBL
  ENSSSCT00035097126.1 UniProtKB/TrEMBL
  ENSSSCT00035097150.1 UniProtKB/TrEMBL
  ENSSSCT00040009841.1 UniProtKB/TrEMBL
  ENSSSCT00040009875.1 UniProtKB/TrEMBL
  ENSSSCT00040009890.1 UniProtKB/TrEMBL
  ENSSSCT00040009903.1 UniProtKB/TrEMBL
  ENSSSCT00045049329.1 UniProtKB/TrEMBL
  ENSSSCT00045049713.1 UniProtKB/TrEMBL
  ENSSSCT00045050262.1 UniProtKB/TrEMBL
  ENSSSCT00045050532.1 UniProtKB/TrEMBL
  ENSSSCT00045050712.1 UniProtKB/TrEMBL
  ENSSSCT00045051063.1 UniProtKB/TrEMBL
  ENSSSCT00060034315.1 UniProtKB/TrEMBL
  ENSSSCT00060034341.1 UniProtKB/TrEMBL
  ENSSSCT00060034351.1 UniProtKB/TrEMBL
  ENSSSCT00060034389.1 UniProtKB/TrEMBL
  ENSSSCT00070026974.1 UniProtKB/TrEMBL
  ENSSSCT00070026977.1 UniProtKB/TrEMBL
  ENSSSCT00070027001.1 UniProtKB/TrEMBL
  ENSSSCT00070027006.1 UniProtKB/TrEMBL
  ENSSSCT00070027011.1 UniProtKB/TrEMBL
  ENSSSCT00070027015.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.50.70 UniProtKB/TrEMBL
  1.50.10.20 UniProtKB/TrEMBL
  2.20.130.20 UniProtKB/TrEMBL
  2.60.120.1540 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  2.60.40.1930 UniProtKB/TrEMBL
  2.60.40.1940 UniProtKB/TrEMBL
  2.60.40.2950 UniProtKB/TrEMBL
  2.60.40.690 UniProtKB/TrEMBL
  6.20.50.160 UniProtKB/TrEMBL
InterPro A-macroglobulin_rcpt-bd UniProtKB/TrEMBL
  A-macroglobulin_rcpt-bd_sf UniProtKB/TrEMBL
  A2M_N_BRD UniProtKB/TrEMBL
  A2M_TED UniProtKB/TrEMBL
  Alpha-macroglob_thiol-ester_cl UniProtKB/TrEMBL
  Alpha-macroglobulin_TED UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
  Macroglobln_a2 UniProtKB/TrEMBL
  MacrogloblnA2_CS UniProtKB/TrEMBL
  MG2 UniProtKB/TrEMBL
  MG3 UniProtKB/TrEMBL
  Terpenoid_cyclase/PrenylTrfase UniProtKB/TrEMBL
KEGG Report ssc:100155478 UniProtKB/TrEMBL
NCBI Gene CD109 ENTREZGENE
PANTHER CD109 ANTIGEN UniProtKB/TrEMBL
  MACROGLOBULIN / COMPLEMENT UniProtKB/TrEMBL
Pfam A2M UniProtKB/TrEMBL
  A2M_BRD UniProtKB/TrEMBL
  A2M_recep UniProtKB/TrEMBL
  MG2 UniProtKB/TrEMBL
  MG3 UniProtKB/TrEMBL
  TED_complement UniProtKB/TrEMBL
PROSITE ALPHA_2_MACROGLOBULIN UniProtKB/TrEMBL
SMART A2M UniProtKB/TrEMBL
  A2M_N_2 UniProtKB/TrEMBL
  A2M_recep UniProtKB/TrEMBL
  Thiol-ester_cl UniProtKB/TrEMBL
Superfamily-SCOP SSF48239 UniProtKB/TrEMBL
  SSF49410 UniProtKB/TrEMBL
  SSF81296 UniProtKB/TrEMBL
UniProt A0A4X1TYA4 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TYC6_PIG UniProtKB/TrEMBL
  A0A4X1TYD0_PIG UniProtKB/TrEMBL
  A0A4X1U395_PIG UniProtKB/TrEMBL
  A0A4X1U3B5_PIG UniProtKB/TrEMBL
  A0A4X1U3Y0_PIG UniProtKB/TrEMBL
  A0A5G2Q991_PIG UniProtKB/TrEMBL
  A0A5G2QKF8_PIG UniProtKB/TrEMBL
  A0A5G2QPT1_PIG UniProtKB/TrEMBL
  A0A5G2R5W3_PIG UniProtKB/TrEMBL
  A0A8D0I3F6_PIG UniProtKB/TrEMBL
  A0A8D0I4S6_PIG UniProtKB/TrEMBL
  A0A8D0IC35_PIG UniProtKB/TrEMBL
  A0A8D0LFP8_PIG UniProtKB/TrEMBL
  A0A8D0LG72_PIG UniProtKB/TrEMBL
  A0A8D0XNQ0_PIG UniProtKB/TrEMBL
  A0A8D0XU23 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0XU32_PIG UniProtKB/TrEMBL
  A0A8D0XUY3_PIG UniProtKB/TrEMBL
  A0A8D1AXL6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1B7H0_PIG UniProtKB/TrEMBL
  A0A8D1B860_PIG UniProtKB/TrEMBL
  A0A8D1ILH1_PIG UniProtKB/TrEMBL
  A0A8D1L3X3_PIG UniProtKB/TrEMBL
  A0A8D1L522_PIG UniProtKB/TrEMBL
  A0A8W4FDJ2_PIG UniProtKB/TrEMBL
  F1RQH9 ENTREZGENE, UniProtKB/TrEMBL
  K7GKY0 ENTREZGENE, UniProtKB/TrEMBL
  K7GP25_PIG UniProtKB/TrEMBL
VGNC ID VGNC:86388 ENTREZGENE