AGBL1 (AGBL carboxypeptidase 1) - Rat Genome Database

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Gene: AGBL1 (AGBL carboxypeptidase 1) Sus scrofa
Analyze
Symbol: AGBL1
Name: AGBL carboxypeptidase 1
RGD ID: 14085592
Description: ENCODES a protein that exhibits tubulin binding (ortholog); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); Corneal Dystrophy, Fuchs Endothelial, 8 (ortholog); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP/GTP binding protein like 1; cytosolic carboxypeptidase 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1192,722,847 - 193,534,417 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11192,725,367 - 193,534,530 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21214,550,551 - 214,964,434 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA)

Cellular Component
cytosol  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
AGBL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1192,722,847 - 193,534,417 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11192,725,367 - 193,534,530 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21214,550,551 - 214,964,434 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AGBL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381586,079,620 - 87,031,476 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1586,079,871 - 87,049,169 (+)EnsemblGRCh38hg38GRCh38
GRCh371586,622,851 - 87,572,283 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361584,486,246 - 85,373,287 (+)NCBINCBI36Build 36hg18NCBI36
Celera1563,086,740 - 63,973,544 (+)NCBICelera
Cytogenetic Map15q25.3NCBI
HuRef1562,798,057 - 63,684,981 (+)NCBIHuRef
CHM1_11586,526,864 - 87,413,136 (+)NCBICHM1_1
T2T-CHM13v2.01583,834,387 - 84,785,395 (+)NCBIT2T-CHM13v2.0
Agbl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39775,879,311 - 76,774,446 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl775,879,635 - 76,774,446 (+)EnsemblGRCm39 Ensembl
GRCm38776,229,591 - 77,124,698 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl776,229,887 - 77,124,698 (+)EnsemblGRCm38mm10GRCm38
MGSCv37783,465,022 - 84,031,140 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36776,284,575 - 76,573,636 (+)NCBIMGSCv36mm8
Celera773,765,804 - 74,340,195 (+)NCBICelera
Cytogenetic Map7D1NCBI
cM Map743.87NCBI
Agbl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81139,453,667 - 140,360,473 (+)NCBIGRCr8
mRatBN7.21130,043,914 - 130,950,739 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1130,043,970 - 130,951,638 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01137,798,862 - 138,711,126 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1137,799,185 - 138,711,126 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01138,789,634 - 139,710,124 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41131,756,893 - 131,944,875 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1122,147,459 - 123,040,161 (+)NCBICelera
Cytogenetic Map1q31NCBI
Agbl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541618,130,605 - 18,686,108 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541617,885,757 - 18,686,124 (-)NCBIChiLan1.0ChiLan1.0
AGBL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21675,629,121 - 76,224,884 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11579,333,797 - 79,929,696 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01564,774,408 - 65,603,628 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11583,986,366 - 84,938,359 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1584,048,348 - 84,938,150 (+)Ensemblpanpan1.1panPan2
AGBL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1349,639,425 - 50,331,421 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl349,639,304 - 50,331,227 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha352,415,838 - 53,000,674 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0350,198,066 - 50,781,019 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl350,060,828 - 50,751,728 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1349,692,597 - 50,306,456 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0349,929,690 - 50,515,701 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0350,269,103 - 50,854,979 (+)NCBIUU_Cfam_GSD_1.0
Agbl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640133,839,393 - 133,880,423 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648312,358,754 - 12,586,674 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648312,358,731 - 13,056,267 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGBL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1294,702,646 - 5,528,743 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl294,703,207 - 5,294,973 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605941,633,731 - 42,381,338 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Agbl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476813,470,674 - 14,239,465 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476813,470,809 - 14,325,563 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in AGBL1
20325 total Variants

Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000062307   ⟹   ENSSSCP00000074870
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1192,722,847 - 193,534,417 (-)Ensembl
RefSeq Acc Id: XM_021062610   ⟹   XP_020918269
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11192,725,367 - 193,534,530 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020918269 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000074870
  ENSSSCP00000074870.1
Reference Protein Sequences
RefSeq Acc Id: XP_020918269   ⟸   XM_021062610
- UniProtKB: A0A8W4F6Q4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000074870   ⟸   ENSSSCT00000062307
Protein Domains
Cytosolic carboxypeptidase N-terminal   Peptidase M14 carboxypeptidase A


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000036551 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000062307 ENTREZGENE
  ENSSSCT00000062307.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.3120 UniProtKB/TrEMBL
  Leucine-rich Repeat Variant UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  CBPC1/4 UniProtKB/TrEMBL
  Pepdidase_M14_N UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
NCBI Gene AGBL1 ENTREZGENE
PANTHER CYTOSOLIC CARBOXYPEPTIDASE UniProtKB/TrEMBL
  CYTOSOLIC CARBOXYPEPTIDASE 4 UniProtKB/TrEMBL
Pfam Pepdidase_M14_N UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
Superfamily-SCOP ARM repeat UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A8W4F6Q4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-02-10 AGBL1  AGBL carboxypeptidase 1  AGBL1  ATP/GTP binding protein like 1  Symbol and/or name change 5135510 APPROVED