SEC14L1 (SEC14 like lipid binding 1) - Rat Genome Database

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Gene: SEC14L1 (SEC14 like lipid binding 1) Sus scrofa
Analyze
Symbol: SEC14L1
Name: SEC14 like lipid binding 1
RGD ID: 14084534
Description: ENCODES a protein that exhibits protein sequestering activity (inferred); RIG-I binding (inferred); INVOLVED IN choline transport (inferred); negative regulation of RIG-I signaling pathway (inferred); ASSOCIATED WITH Monoclonal B-Cell Lymphocytosis (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); Golgi apparatus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SEC14-like 1; SEC14-like protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl124,441,114 - 4,489,081 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1124,439,045 - 4,489,078 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2124,186,754 - 4,236,079 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)
cytosol  (IBA,IEA)
Golgi apparatus  (IEA)
nucleoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SEC14L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl124,441,114 - 4,489,081 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1124,439,045 - 4,489,078 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2124,186,754 - 4,236,079 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SEC14L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381777,088,685 - 77,217,101 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1777,088,749 - 77,217,101 (+)EnsemblGRCh38hg38GRCh38
GRCh371775,084,767 - 75,213,183 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361772,648,647 - 72,724,778 (+)NCBINCBI36Build 36hg18NCBI36
Build 341772,648,616 - 72,724,774NCBI
Celera1771,732,575 - 71,808,664 (+)NCBICelera
Cytogenetic Map17q25.2-q25.3NCBI
HuRef1770,511,931 - 70,641,030 (+)NCBIHuRef
CHM1_11775,149,639 - 75,278,075 (+)NCBICHM1_1
T2T-CHM13v2.01777,981,537 - 78,110,663 (+)NCBIT2T-CHM13v2.0
Sec14l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911117,005,994 - 117,050,094 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11117,005,994 - 117,050,094 (+)EnsemblGRCm39 Ensembl
GRCm3811117,115,168 - 117,159,268 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11117,115,168 - 117,159,268 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711116,976,486 - 117,020,582 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611116,931,339 - 116,975,311 (+)NCBIMGSCv36mm8
Celera11128,859,607 - 128,903,470 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1181.99NCBI
Sec14l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810102,818,693 - 102,865,841 (+)NCBIGRCr8
mRatBN7.210102,319,920 - 102,367,070 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10102,319,920 - 102,367,068 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10107,422,983 - 107,470,216 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010106,886,082 - 106,933,320 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010102,240,737 - 102,287,882 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010106,065,712 - 106,112,859 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10106,065,712 - 106,112,857 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010105,718,075 - 105,765,282 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410107,220,734 - 107,267,940 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera10100,886,819 - 100,933,978 (+)NCBICelera
Cytogenetic Map10q32.2NCBI
Sec14l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555065,158,805 - 5,232,551 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555065,159,090 - 5,231,827 (-)NCBIChiLan1.0ChiLan1.0
SEC14L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21993,194,000 - 93,269,776 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11798,023,131 - 98,098,962 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01771,221,870 - 71,297,142 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11776,730,168 - 76,857,856 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1776,785,559 - 76,857,848 (+)Ensemblpanpan1.1panPan2
SEC14L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.193,683,328 - 3,740,271 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl93,659,451 - 3,739,213 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha94,365,609 - 4,422,239 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.094,360,709 - 4,417,642 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl94,360,714 - 4,417,622 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.194,384,488 - 4,441,395 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.094,505,242 - 4,562,080 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.094,587,564 - 4,644,483 (-)NCBIUU_Cfam_GSD_1.0
Sec14l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056024,303,778 - 4,363,669 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365942,048,054 - 2,100,859 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365942,048,146 - 2,100,808 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEC14L1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11644,490,927 - 44,565,922 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1644,489,852 - 44,565,853 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607715,216,709 - 15,293,938 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sec14l1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248016,890,134 - 6,945,443 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248016,890,278 - 6,942,724 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SEC14L1
1779 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 2 4 5 2 1 1
Low 8 2 3 1 2 18 2 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000018693   ⟹   ENSSSCP00000018192
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl124,441,114 - 4,489,081 (-)Ensembl
RefSeq Acc Id: XM_005653864   ⟹   XP_005653921
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1124,439,045 - 4,489,078 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005653921 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000018192
  ENSSSCP00000018192.4
  ENSSSCP00015023143.1
Reference Protein Sequences
RefSeq Acc Id: XP_005653921   ⟸   XM_005653864
- UniProtKB: A0A480J515 (UniProtKB/TrEMBL),   A0A8D0NTK0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000018192   ⟸   ENSSSCT00000018693
Protein Domains
CRAL-TRIO   GOLD   PRELI/MSF1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000017169 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015042833 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000018693 ENTREZGENE
  ENSSSCT00000018693.5 UniProtKB/TrEMBL
  ENSSSCT00015057744.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.525.10 UniProtKB/TrEMBL
  GOLD domain UniProtKB/TrEMBL
InterPro CRAL-TRIO_dom UniProtKB/TrEMBL
  CRAL-TRIO_dom_sf UniProtKB/TrEMBL
  CRAL/TRIO_N_dom UniProtKB/TrEMBL
  CRAL/TRIO_N_dom_sf UniProtKB/TrEMBL
  GOLD_dom UniProtKB/TrEMBL
  GOLD_dom_sf UniProtKB/TrEMBL
  PRELI/MSF1_dom UniProtKB/TrEMBL
KEGG Report ssc:100515921 UniProtKB/TrEMBL
NCBI Gene SEC14L1 ENTREZGENE
PANTHER SEC14 RELATED PROTEIN UniProtKB/TrEMBL
  SEC14-LIKE PROTEIN 1 UniProtKB/TrEMBL
Pfam CRAL_TRIO UniProtKB/TrEMBL
  CRAL_TRIO_N UniProtKB/TrEMBL
  PRELI UniProtKB/TrEMBL
PROSITE CRAL_TRIO UniProtKB/TrEMBL
  GOLD UniProtKB/TrEMBL
  PRELI_MSF1 UniProtKB/TrEMBL
SMART CRAL_TRIO_N UniProtKB/TrEMBL
  SEC14 UniProtKB/TrEMBL
Superfamily-SCOP SSF101576 UniProtKB/TrEMBL
  SSF46938 UniProtKB/TrEMBL
  SSF52087 UniProtKB/TrEMBL
UniProt A0A480J515 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0NTK0 ENTREZGENE, UniProtKB/TrEMBL
  F1RZ70_PIG UniProtKB/TrEMBL
VGNC ID VGNC:92669 ENTREZGENE