KIR2DL1 (killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1) - Rat Genome Database

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Gene: KIR2DL1 (killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1) Sus scrofa
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Symbol: KIR2DL1
Name: killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
RGD ID: 14077926
Description: ENCODES a protein that exhibits MHC class Ib receptor activity (inferred); INVOLVED IN natural killer cell inhibitory signaling pathway (ortholog); ASSOCIATED WITH acquired immunodeficiency syndrome (ortholog); COVID-19 (ortholog); HIV Seropositivity (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: killer cell immunoglobulin-like receptor 2DL1; killer cell immunoglobulin-like receptor 2DL5A
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl659,056,794 - 59,067,573 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1659,056,497 - 59,068,225 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2653,980,484 - 53,991,258 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap6qNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:16738944   PMID:29931472  


Genomics

Comparative Map Data
KIR2DL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl659,056,794 - 59,067,573 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1659,056,497 - 59,068,225 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2653,980,484 - 53,991,258 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap6qNCBI
KIR2DL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381954,769,793 - 54,784,322 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1954,769,793 - 54,784,322 (+)EnsemblGRCh38hg38GRCh38
GRCh371955,281,245 - 55,295,774 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361959,973,077 - 59,987,590 (+)NCBINCBI36Build 36hg18NCBI36
Build 341959,973,091 - 59,987,590NCBI
Celera1952,321,969 - 52,336,480 (+)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1951,603,927 - 51,618,440 (+)NCBIHuRef
CHM1_11955,274,832 - 55,289,346 (+)NCBICHM1_1
T2T-CHM13v2.01957,864,064 - 57,878,595 (+)NCBIT2T-CHM13v2.0

Variants

.
Variants in KIR2DL1
81 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system
High
Medium
Low 1 1 2 1
Below cutoff 3 1 2 1

Sequence


RefSeq Acc Id: ENSSSCT00000054174   ⟹   ENSSSCP00000043861
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl659,056,794 - 59,067,573 (+)Ensembl
RefSeq Acc Id: NM_001113218   ⟹   NP_001106689
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1659,056,794 - 59,067,573 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021093201   ⟹   XP_020948860
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1659,056,497 - 59,068,225 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020948860   ⟸   XM_021093201
- Peptide Label: isoform X1
- UniProtKB: A0A8D0HYL9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001106689   ⟸   NM_001113218
- Peptide Label: precursor
- UniProtKB: A0A287AIY8 (UniProtKB/TrEMBL),   A0A4X1VJD4 (UniProtKB/TrEMBL),   A0A8D0HYL9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000043861   ⟸   ENSSSCT00000054174
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000033933 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005006094 UniProtKB/TrEMBL
  ENSSSCG00015003304 UniProtKB/TrEMBL
  ENSSSCG00025065725 UniProtKB/TrEMBL
  ENSSSCG00030022553 UniProtKB/TrEMBL
  ENSSSCG00035053089 UniProtKB/TrEMBL
  ENSSSCG00040062224 UniProtKB/TrEMBL
  ENSSSCG00045035508 UniProtKB/TrEMBL
  ENSSSCG00050065361 UniProtKB/TrEMBL
  ENSSSCG00055015070 UniProtKB/TrEMBL
  ENSSSCG00060044669 UniProtKB/TrEMBL
  ENSSSCG00065006269 UniProtKB/TrEMBL
  ENSSSCG00070024654 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000054174 ENTREZGENE
  ENSSSCT00000054174.1 UniProtKB/TrEMBL
  ENSSSCT00005009230.1 UniProtKB/TrEMBL
  ENSSSCT00015004193.1 UniProtKB/TrEMBL
  ENSSSCT00025090218.1 UniProtKB/TrEMBL
  ENSSSCT00030031313.1 UniProtKB/TrEMBL
  ENSSSCT00035070834.1 UniProtKB/TrEMBL
  ENSSSCT00040084718.1 UniProtKB/TrEMBL
  ENSSSCT00045060967.1 UniProtKB/TrEMBL
  ENSSSCT00050089018.1 UniProtKB/TrEMBL
  ENSSSCT00055029712.1 UniProtKB/TrEMBL
  ENSSSCT00060060579.1 UniProtKB/TrEMBL
  ENSSSCT00065008444.1 UniProtKB/TrEMBL
  ENSSSCT00070049199.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/TrEMBL
KEGG Report ssc:100127456 UniProtKB/TrEMBL
NCBI Gene KIR2DL1 ENTREZGENE
PANTHER KIR2DL PROTEIN-RELATED UniProtKB/TrEMBL
  MHC CLASS I NK CELL RECEPTOR UniProtKB/TrEMBL
Pfam PF00047 UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A287AIY8 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1VJD4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0HYL9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1L7V1_PIG UniProtKB/TrEMBL