ENC1 (ectodermal-neural cortex 1) - Rat Genome Database

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Gene: ENC1 (ectodermal-neural cortex 1) Sus scrofa
Analyze
Symbol: ENC1
Name: ectodermal-neural cortex 1
RGD ID: 14061374
Description: INVOLVED IN positive regulation of neuron projection development (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Neurodevelopmental Disorders (ortholog); Sandhoff Disease, Infantile Type (ortholog); FOUND IN chromatin (ortholog); neuronal cell body (ortholog); nuclear matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ectoderm-neural cortex protein 1; ectodermal-neural cortex 1 (with BTB-like domain)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl283,678,521 - 83,691,400 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1283,678,518 - 83,691,812 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2285,271,292 - 85,284,204 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074  


Genomics

Comparative Map Data
ENC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl283,678,521 - 83,691,400 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1283,678,518 - 83,691,812 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2285,271,292 - 85,284,204 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ENC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38574,627,409 - 74,640,728 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl574,627,406 - 74,641,424 (-)EnsemblGRCh38hg38GRCh38
GRCh37573,923,234 - 73,936,553 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36573,958,990 - 73,972,273 (-)NCBINCBI36Build 36hg18NCBI36
Build 34573,958,990 - 73,972,273NCBI
Celera569,818,021 - 69,832,031 (-)NCBICelera
Cytogenetic Map5q13.3NCBI
HuRef569,128,052 - 69,142,065 (-)NCBIHuRef
CHM1_1573,355,796 - 73,369,813 (-)NCBICHM1_1
T2T-CHM13v2.0575,108,382 - 75,121,693 (-)NCBIT2T-CHM13v2.0
Enc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391397,377,613 - 97,389,548 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1397,377,613 - 97,389,542 (+)EnsemblGRCm39 Ensembl
GRCm381397,241,105 - 97,253,040 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1397,241,105 - 97,253,034 (+)EnsemblGRCm38mm10GRCm38
MGSCv371398,011,060 - 98,022,995 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361398,341,869 - 98,353,733 (+)NCBIMGSCv36mm8
Celera13100,873,931 - 100,885,879 (+)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1350.66NCBI
Enc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8230,285,274 - 30,297,194 (+)NCBIGRCr8
mRatBN7.2228,550,670 - 28,562,591 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl228,550,464 - 28,562,713 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx235,605,171 - 35,617,034 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0233,699,505 - 33,711,368 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0228,519,264 - 28,531,129 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0228,049,217 - 28,061,023 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl228,049,217 - 28,061,029 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0247,160,036 - 47,171,842 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4227,720,805 - 27,733,168 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1227,364,788 - 27,653,537 (+)NCBI
Celera224,591,966 - 24,603,770 (+)NCBICelera
Cytogenetic Map2q12NCBI
Enc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542526,017,684 - 26,029,262 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542526,017,684 - 26,029,262 (+)NCBIChiLan1.0ChiLan1.0
ENC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2440,671,223 - 40,684,243 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1538,824,858 - 38,837,878 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0540,668,899 - 40,682,887 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1541,276,022 - 41,290,189 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl541,281,115 - 41,282,884 (+)Ensemblpanpan1.1panPan2
ENC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1257,175,851 - 57,184,445 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl257,182,480 - 57,184,249 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha254,153,002 - 54,164,687 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0257,699,330 - 57,711,010 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl257,701,049 - 57,710,976 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1254,763,393 - 54,775,077 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0255,526,509 - 55,538,190 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0256,423,533 - 56,435,224 (-)NCBIUU_Cfam_GSD_1.0
Enc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213188,837,852 - 188,850,667 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365492,008,363 - 2,020,948 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365492,008,365 - 2,020,948 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ENC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1468,980,137 - 68,994,112 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl468,987,452 - 68,989,218 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604917,758,086 - 17,772,066 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Enc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624924281,327 - 294,248 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624924281,251 - 294,248 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ENC1
319 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 11
Low 9 4 3 5 10 2 2 1
Below cutoff 1 2 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000015372   ⟹   ENSSSCP00000014964
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl283,684,329 - 83,689,242 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000094800   ⟹   ENSSSCP00000074736
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl283,678,521 - 83,691,400 (-)Ensembl
RefSeq Acc Id: XM_003123701   ⟹   XP_003123749
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1283,678,518 - 83,691,812 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021084447   ⟹   XP_020940106
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1283,678,518 - 83,690,735 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003123749   ⟸   XM_003123701
- UniProtKB: A0A480LCH7 (UniProtKB/TrEMBL),   A0A4X1SNA4 (UniProtKB/TrEMBL),   F1S2J9 (UniProtKB/TrEMBL),   A0A8D1GF32 (UniProtKB/TrEMBL),   A0A8D1YME2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020940106   ⟸   XM_021084447
- UniProtKB: A0A480LCH7 (UniProtKB/TrEMBL),   A0A4X1SNA4 (UniProtKB/TrEMBL),   F1S2J9 (UniProtKB/TrEMBL),   A0A8D1GF32 (UniProtKB/TrEMBL),   A0A8D1YME2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000014964   ⟸   ENSSSCT00000015372
RefSeq Acc Id: ENSSSCP00000074736   ⟸   ENSSSCT00000094800
Protein Domains
BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014072 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005009103 UniProtKB/TrEMBL
  ENSSSCG00015017449 UniProtKB/TrEMBL
  ENSSSCG00025013594 UniProtKB/TrEMBL
  ENSSSCG00030067307 UniProtKB/TrEMBL
  ENSSSCG00035034534 UniProtKB/TrEMBL
  ENSSSCG00040072575 UniProtKB/TrEMBL
  ENSSSCG00045002801 UniProtKB/TrEMBL
  ENSSSCG00050033289 UniProtKB/TrEMBL
  ENSSSCG00055001322 UniProtKB/TrEMBL
  ENSSSCG00060001916 UniProtKB/TrEMBL
  ENSSSCG00065038310 UniProtKB/TrEMBL
  ENSSSCG00070002519 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000015372 ENTREZGENE
  ENSSSCT00000015372.4 UniProtKB/TrEMBL
  ENSSSCT00000094800 ENTREZGENE
  ENSSSCT00000094800.1 UniProtKB/TrEMBL
  ENSSSCT00005013884.1 UniProtKB/TrEMBL
  ENSSSCT00015023040.1 UniProtKB/TrEMBL
  ENSSSCT00015023086.1 UniProtKB/TrEMBL
  ENSSSCT00025018039.1 UniProtKB/TrEMBL
  ENSSSCT00025018072.1 UniProtKB/TrEMBL
  ENSSSCT00030094108.1 UniProtKB/TrEMBL
  ENSSSCT00030094128.1 UniProtKB/TrEMBL
  ENSSSCT00035045754.1 UniProtKB/TrEMBL
  ENSSSCT00035045760.1 UniProtKB/TrEMBL
  ENSSSCT00040099975.1 UniProtKB/TrEMBL
  ENSSSCT00045004397.1 UniProtKB/TrEMBL
  ENSSSCT00045004401.1 UniProtKB/TrEMBL
  ENSSSCT00050044629.1 UniProtKB/TrEMBL
  ENSSSCT00055002396.1 UniProtKB/TrEMBL
  ENSSSCT00055002409.1 UniProtKB/TrEMBL
  ENSSSCT00060002332.1 UniProtKB/TrEMBL
  ENSSSCT00065052362.1 UniProtKB/TrEMBL
  ENSSSCT00065052368.1 UniProtKB/TrEMBL
  ENSSSCT00070004687.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.420 UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/TrEMBL
InterPro BACK UniProtKB/TrEMBL
  BTB-kelch_protein UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/TrEMBL
  ENC1 UniProtKB/TrEMBL
  ENC1_BACK UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
KEGG Report ssc:100517459 UniProtKB/TrEMBL
NCBI Gene ENC1 ENTREZGENE
PANTHER ACTIN-BINDING PROTEIN IPP UniProtKB/TrEMBL
  KELCH PROTEIN UniProtKB/TrEMBL
Pfam BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
PIRSF Kelch-like_protein_gigaxonin UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
SMART BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch UniProtKB/TrEMBL
Superfamily-SCOP SSF117281 UniProtKB/TrEMBL
  SSF54695 UniProtKB/TrEMBL
UniProt A0A480LCH7 ENTREZGENE
  A0A4X1SNA4 ENTREZGENE
  A0A8D0Y142_PIG UniProtKB/TrEMBL
  A0A8D1GF32 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1YME2 ENTREZGENE, UniProtKB/TrEMBL
  F1S2J9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A480LCH7 UniProtKB/TrEMBL
  A0A4X1SNA4 UniProtKB/TrEMBL
VGNC ID VGNC:87696 ENTREZGENE