PCBD2 (pterin-4 alpha-carbinolamine dehydratase 2) - Rat Genome Database

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Gene: PCBD2 (pterin-4 alpha-carbinolamine dehydratase 2) Sus scrofa
Analyze
Symbol: PCBD2
Name: pterin-4 alpha-carbinolamine dehydratase 2
RGD ID: 14034352
Description: ENCODES a protein that exhibits identical protein binding (ortholog); phenylalanine 4-monooxygenase activity (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pterin-4-alpha-carbinolamine dehydratase 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.12137,082,920 - 137,135,175 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PCBD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.12137,082,920 - 137,135,175 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PCBD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385134,905,131 - 134,962,644 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5134,905,120 - 135,007,959 (+)EnsemblGRCh38hg38GRCh38
GRCh375134,240,821 - 134,298,334 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365134,268,709 - 134,326,235 (+)NCBINCBI36Build 36hg18NCBI36
Build 345134,268,708 - 134,333,243NCBI
Celera5130,369,123 - 130,422,077 (+)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5129,426,903 - 129,486,276 (+)NCBIHuRef
CHM1_15133,673,459 - 133,730,983 (+)NCBICHM1_1
T2T-CHM13v2.05135,432,093 - 135,489,611 (+)NCBIT2T-CHM13v2.0
Pcbd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391355,874,957 - 55,924,643 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1355,875,181 - 55,924,643 (+)EnsemblGRCm39 Ensembl
GRCm381355,727,097 - 55,776,830 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1355,727,368 - 55,776,830 (+)EnsemblGRCm38mm10GRCm38
MGSCv371355,828,729 - 55,878,191 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361355,736,990 - 55,786,452 (+)NCBIMGSCv36mm8
Celera1356,782,245 - 56,831,727 (+)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1330.06NCBI
Pcbd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,850,349 - 8,902,420 (-)NCBIGRCr8
mRatBN7.2178,845,161 - 8,896,343 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,845,084 - 8,910,539 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx178,860,830 - 8,911,884 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01710,390,105 - 10,441,472 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0178,857,211 - 8,908,265 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0178,929,675 - 8,980,712 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl178,929,810 - 8,980,571 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01711,094,438 - 11,145,446 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera178,927,317 - 8,977,982 (-)NCBICelera
Cytogenetic Map17p14NCBI
Pcbd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540830,090,808 - 30,137,964 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540830,090,808 - 30,137,894 (+)NCBIChiLan1.0ChiLan1.0
PCBD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24130,199,520 - 130,260,300 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15128,338,958 - 128,399,860 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05130,303,900 - 130,364,899 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15136,446,464 - 136,497,528 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5136,446,730 - 136,497,011 (+)Ensemblpanpan1.1panPan2
PCBD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11122,998,005 - 23,015,572 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1122,951,201 - 23,015,572 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1121,711,021 - 21,765,150 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01123,768,358 - 23,822,149 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1123,768,124 - 23,822,149 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11122,467,615 - 22,521,350 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01122,333,522 - 22,387,288 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01122,976,012 - 23,030,046 (+)NCBIUU_Cfam_GSD_1.0
Pcbd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213123,089,793 - 123,136,422 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365972,119,136 - 2,161,379 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365972,113,428 - 2,161,329 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PCBD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12337,689,451 - 37,737,997 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2337,689,506 - 37,738,161 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603440,178,570 - 40,227,682 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pcbd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473312,113,915 - 12,162,222 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473312,113,915 - 12,162,224 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PCBD2
1898 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 4 3 5 2 22 2 2 3
Low 1 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: XM_021084778   ⟹   XP_020940437
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12137,082,920 - 137,135,175 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020940437   ⟸   XM_021084778
- UniProtKB: A0A4X1V3R6 (UniProtKB/TrEMBL),   A0A481C1I2 (UniProtKB/TrEMBL),   A0A480Y9L7 (UniProtKB/TrEMBL),   A0A8D1ZMZ2 (UniProtKB/TrEMBL)
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00015027484 UniProtKB/TrEMBL
  ENSSSCG00030004923 UniProtKB/TrEMBL
  ENSSSCG00035055989 UniProtKB/TrEMBL
  ENSSSCG00040014888 UniProtKB/TrEMBL
  ENSSSCG00045016199 UniProtKB/TrEMBL
  ENSSSCG00050077360 UniProtKB/TrEMBL
  ENSSSCG00055011894 UniProtKB/TrEMBL
  ENSSSCG00065058684 UniProtKB/TrEMBL
  ENSSSCG00070021193 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00015036822.1 UniProtKB/TrEMBL
  ENSSSCT00030006647.1 UniProtKB/TrEMBL
  ENSSSCT00030006651.1 UniProtKB/TrEMBL
  ENSSSCT00035074714.1 UniProtKB/TrEMBL
  ENSSSCT00040019984.1 UniProtKB/TrEMBL
  ENSSSCT00045027559.1 UniProtKB/TrEMBL
  ENSSSCT00050106460.1 UniProtKB/TrEMBL
  ENSSSCT00055023296.1 UniProtKB/TrEMBL
  ENSSSCT00065080297.1 UniProtKB/TrEMBL
  ENSSSCT00070042097.1 UniProtKB/TrEMBL
  ENSSSCT00070042102.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1360.20 UniProtKB/TrEMBL
InterPro PCD_sf UniProtKB/TrEMBL
  Pterin_deHydtase UniProtKB/TrEMBL
NCBI Gene PCBD2 ENTREZGENE
PANTHER PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE 2 UniProtKB/TrEMBL
  PTHR12599 UniProtKB/TrEMBL
Pfam Pterin_4a UniProtKB/TrEMBL
Superfamily-SCOP SSF55248 UniProtKB/TrEMBL
UniProt A0A480Y9L7 ENTREZGENE, UniProtKB/TrEMBL
  A0A481C1I2 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V3R6 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V3R9_PIG UniProtKB/TrEMBL
  A0A8D0VA15_PIG UniProtKB/TrEMBL
  A0A8D1ZMZ2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:100319 ENTREZGENE