BEND6 (BEN domain containing 6) - Rat Genome Database

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Gene: BEND6 (BEN domain containing 6) Sus scrofa
Analyze
Symbol: BEND6
Name: BEN domain containing 6
RGD ID: 14007963
Description: ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); transcription corepressor activity (inferred); INVOLVED IN negative regulation of Notch signaling pathway (ortholog); positive regulation of neuron differentiation (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BEN domain-containing protein 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl728,769,902 - 28,811,933 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1728,769,888 - 28,811,923 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2733,231,064 - 33,273,079 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
BEND6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl728,769,902 - 28,811,933 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1728,769,888 - 28,811,923 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2733,231,064 - 33,273,079 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BEND6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38656,955,107 - 57,027,346 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl656,955,107 - 57,027,346 (+)EnsemblGRCh38hg38GRCh38
GRCh37656,819,905 - 56,892,144 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36656,927,732 - 57,000,103 (+)NCBINCBI36Build 36hg18NCBI36
Build 34656,928,048 - 57,000,099NCBI
Celera658,482,926 - 58,555,295 (+)NCBICelera
Cytogenetic Map6p12.1NCBI
HuRef656,653,688 - 56,725,834 (+)NCBIHuRef
CHM1_1656,820,114 - 56,892,458 (+)NCBICHM1_1
T2T-CHM13v2.0656,794,154 - 56,866,397 (+)NCBIT2T-CHM13v2.0
Bend6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39133,891,133 - 33,946,925 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl133,891,133 - 33,946,897 (-)EnsemblGRCm39 Ensembl
GRCm38133,852,052 - 33,907,933 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl133,852,052 - 33,907,816 (-)EnsemblGRCm38mm10GRCm38
MGSCv37133,908,897 - 33,964,466 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36133,796,598 - 33,852,167 (-)NCBIMGSCv36mm8
Celera133,626,568 - 33,682,229 (-)NCBICelera
Cytogenetic Map1BNCBI
cM Map112.85NCBI
Bend6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8943,576,982 - 43,631,437 (-)NCBIGRCr8
mRatBN7.2936,081,033 - 36,135,309 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl936,081,484 - 36,135,228 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx944,577,961 - 44,632,176 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0949,709,148 - 49,763,363 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0947,991,063 - 48,045,276 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0938,297,253 - 38,351,312 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl938,297,322 - 38,351,024 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0937,980,049 - 38,033,453 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4932,598,694 - 32,656,071 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1932,563,161 - 32,633,061 (-)NCBI
Celera933,873,992 - 33,927,321 (-)NCBICelera
Cytogenetic Map9q21NCBI
Bend6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555023,124,202 - 3,143,278 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555023,123,024 - 3,152,121 (-)NCBIChiLan1.0ChiLan1.0
BEND6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2571,452,447 - 71,498,338 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1667,307,286 - 67,379,764 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0656,513,496 - 56,586,227 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1658,144,948 - 58,216,965 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl658,144,948 - 58,216,965 (+)Ensemblpanpan1.1panPan2
BEND6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11224,195,068 - 24,254,098 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1224,195,899 - 24,253,229 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1224,084,247 - 24,143,298 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01224,693,267 - 24,752,305 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1224,693,165 - 24,752,298 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11224,190,941 - 24,249,996 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01224,291,978 - 24,351,309 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01224,423,435 - 24,482,648 (+)NCBIUU_Cfam_GSD_1.0
Bend6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494659,616,217 - 59,681,950 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364764,279,491 - 4,317,431 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364764,278,306 - 4,344,085 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BEND6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11714,576,290 - 14,651,878 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1714,576,080 - 14,651,671 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605820,682,525 - 20,758,355 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bend6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475318,795,568 - 18,823,842 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475318,778,611 - 18,848,599 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in BEND6
1573 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 14
Low 4 2 3 2 9 2 3
Below cutoff 6 2 3 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000001670   ⟹   ENSSSCP00000001626
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl728,769,902 - 28,811,933 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000052436   ⟹   ENSSSCP00000049810
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl728,786,151 - 28,811,933 (-)Ensembl
RefSeq Acc Id: XM_001925201   ⟹   XP_001925236
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1728,769,888 - 28,811,923 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005665866   ⟹   XP_005665923
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1728,769,888 - 28,811,899 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013977762   ⟹   XP_013833216
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1728,779,951 - 28,811,899 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_001925236   ⟸   XM_001925201
- Peptide Label: isoform X1
- UniProtKB: F1RZU9 (UniProtKB/TrEMBL),   A0A8D1CJF8 (UniProtKB/TrEMBL),   A0A480HTH1 (UniProtKB/TrEMBL),   A0A8D0SSP7 (UniProtKB/TrEMBL),   A0A8D1NVL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005665923   ⟸   XM_005665866
- Peptide Label: isoform X2
- UniProtKB: A0A480HTH1 (UniProtKB/TrEMBL),   A0A8D0SSP7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013833216   ⟸   XM_013977762
- Peptide Label: isoform X1
- UniProtKB: F1RZU9 (UniProtKB/TrEMBL),   A0A8D1CJF8 (UniProtKB/TrEMBL),   A0A480HTH1 (UniProtKB/TrEMBL),   A0A8D0SSP7 (UniProtKB/TrEMBL),   A0A8D1NVL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000001626   ⟸   ENSSSCT00000001670
RefSeq Acc Id: ENSSSCP00000049810   ⟸   ENSSSCT00000052436
Protein Domains
BEN


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000001498 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005042471 UniProtKB/TrEMBL
  ENSSSCG00015020125 UniProtKB/TrEMBL
  ENSSSCG00025056045 UniProtKB/TrEMBL
  ENSSSCG00030074994 UniProtKB/TrEMBL
  ENSSSCG00035023069 UniProtKB/TrEMBL
  ENSSSCG00040041184 UniProtKB/TrEMBL
  ENSSSCG00045039231 UniProtKB/TrEMBL
  ENSSSCG00050072474 UniProtKB/TrEMBL
  ENSSSCG00055030906 UniProtKB/TrEMBL
  ENSSSCG00060033484 UniProtKB/TrEMBL
  ENSSSCG00065040471 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000001670 ENTREZGENE
  ENSSSCT00000001670.5 UniProtKB/TrEMBL
  ENSSSCT00000052436.3 UniProtKB/TrEMBL
  ENSSSCT00005068087.1 UniProtKB/TrEMBL
  ENSSSCT00005068115.1 UniProtKB/TrEMBL
  ENSSSCT00005068165.1 UniProtKB/TrEMBL
  ENSSSCT00005068192.1 UniProtKB/TrEMBL
  ENSSSCT00015026608.1 UniProtKB/TrEMBL
  ENSSSCT00015026729.1 UniProtKB/TrEMBL
  ENSSSCT00025076679.1 UniProtKB/TrEMBL
  ENSSSCT00025076746.1 UniProtKB/TrEMBL
  ENSSSCT00030105434.1 UniProtKB/TrEMBL
  ENSSSCT00030105435.1 UniProtKB/TrEMBL
  ENSSSCT00030105436.1 UniProtKB/TrEMBL
  ENSSSCT00035030188.1 UniProtKB/TrEMBL
  ENSSSCT00035030190.1 UniProtKB/TrEMBL
  ENSSSCT00040055061.1 UniProtKB/TrEMBL
  ENSSSCT00040055128.1 UniProtKB/TrEMBL
  ENSSSCT00045068282.1 UniProtKB/TrEMBL
  ENSSSCT00045068285.1 UniProtKB/TrEMBL
  ENSSSCT00050098944.1 UniProtKB/TrEMBL
  ENSSSCT00050098945.1 UniProtKB/TrEMBL
  ENSSSCT00055061682.1 UniProtKB/TrEMBL
  ENSSSCT00055061683.1 UniProtKB/TrEMBL
  ENSSSCT00060045402.1 UniProtKB/TrEMBL
  ENSSSCT00060045408.1 UniProtKB/TrEMBL
  ENSSSCT00065055318.1 UniProtKB/TrEMBL
  ENSSSCT00065055321.1 UniProtKB/TrEMBL
Gene3D-CATH BEN domain UniProtKB/TrEMBL
InterPro BEN_domain UniProtKB/TrEMBL
  BEND6 UniProtKB/TrEMBL
KEGG Report ssc:100153820 UniProtKB/TrEMBL
NCBI Gene BEND6 ENTREZGENE
PANTHER BEN DOMAIN-CONTAINING PROTEIN 6 UniProtKB/TrEMBL
  PTHR35346 UniProtKB/TrEMBL
Pfam BEN UniProtKB/TrEMBL
PROSITE BEN UniProtKB/TrEMBL
SMART BEN UniProtKB/TrEMBL
UniProt A0A480HTH1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0LYY4_PIG UniProtKB/TrEMBL
  A0A8D0SSP7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1CJF8 ENTREZGENE
  A0A8D1NUJ9_PIG UniProtKB/TrEMBL
  A0A8D1NVL0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1SRS1_PIG UniProtKB/TrEMBL
  F1RZU9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A287B079 UniProtKB/TrEMBL
  A0A8D1CJF8 UniProtKB/TrEMBL
VGNC ID VGNC:85802 ENTREZGENE