KCTD18 (potassium channel tetramerization domain containing 18) - Rat Genome Database

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Gene: KCTD18 (potassium channel tetramerization domain containing 18) Sus scrofa
Analyze
Symbol: KCTD18
Name: potassium channel tetramerization domain containing 18
RGD ID: 13999375
Description: INVOLVED IN protein homooligomerization (inferred); ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); Primary Pulmonary Hypertension, 1 (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BTB/POZ domain-containing protein KCTD18
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15104,071,268 - 104,099,188 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115104,070,208 - 104,099,300 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215115,343,268 - 115,371,296 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
KCTD18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15104,071,268 - 104,099,188 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115104,070,208 - 104,099,300 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215115,343,268 - 115,371,296 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCTD18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382200,488,958 - 200,510,068 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2200,488,958 - 200,519,784 (-)EnsemblGRCh38hg38GRCh38
GRCh372201,353,681 - 201,374,791 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362201,061,926 - 201,083,037 (-)NCBINCBI36Build 36hg18NCBI36
Build 342201,179,191 - 201,200,298NCBI
Celera2195,108,519 - 195,129,627 (-)NCBICelera
Cytogenetic Map2q33.1NCBI
HuRef2193,206,069 - 193,227,176 (-)NCBIHuRef
CHM1_12201,359,660 - 201,380,767 (-)NCBICHM1_1
T2T-CHM13v2.02200,972,443 - 200,993,548 (-)NCBIT2T-CHM13v2.0
Kctd18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39157,994,260 - 58,009,298 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl157,994,260 - 58,058,115 (-)EnsemblGRCm39 Ensembl
GRCm38157,955,101 - 57,970,141 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl157,955,101 - 58,018,956 (-)EnsemblGRCm38mm10GRCm38
MGSCv37158,011,945 - 58,026,928 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36157,904,600 - 57,914,598 (-)NCBIMGSCv36mm8
Celera158,468,917 - 58,483,900 (-)NCBICelera
Cytogenetic Map1C1.3NCBI
cM Map128.86NCBI
Kctd18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8966,996,440 - 67,061,069 (-)NCBIGRCr8
mRatBN7.2959,502,220 - 59,566,857 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl959,502,232 - 59,566,857 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx968,002,289 - 68,066,928 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0973,118,202 - 73,182,841 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0971,436,305 - 71,500,944 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0964,849,547 - 64,916,652 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl964,852,289 - 64,916,652 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0964,649,827 - 64,714,190 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4956,616,134 - 56,680,759 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera956,948,290 - 57,012,301 (-)NCBICelera
Cytogenetic Map9q31NCBI
Kctd18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955403913,621 - 923,631 (+)NCBIChiLan1.0ChiLan1.0
KCTD18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213103,111,729 - 103,132,969 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B103,126,709 - 103,147,919 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B87,742,323 - 87,763,530 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B205,900,029 - 205,920,776 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B205,900,032 - 205,920,776 (-)Ensemblpanpan1.1panPan2
KCTD18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1379,574,407 - 9,593,978 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl379,588,386 - 9,596,158 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3710,461,760 - 10,482,875 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0379,474,410 - 9,495,528 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl379,474,397 - 9,495,713 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1379,461,767 - 9,481,279 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0379,434,021 - 9,453,540 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0379,433,016 - 9,454,130 (-)NCBIUU_Cfam_GSD_1.0
Kctd18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303157,612,152 - 157,631,228 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936825398,875 - 413,993 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936825396,359 - 415,478 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCTD18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11085,986,243 - 86,005,518 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1085,987,397 - 86,002,429 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040113,362,357 - 113,453,417 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kctd18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624889572,064 - 589,386 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in KCTD18
961 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 10 4 3 5 2 23 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000017519   ⟹   ENSSSCP00000017047
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15104,071,268 - 104,099,188 (-)Ensembl
RefSeq Acc Id: XM_003133574   ⟹   XP_003133622
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115104,070,208 - 104,099,300 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001301538
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115104,071,268 - 104,099,300 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003133622   ⟸   XM_003133574
- UniProtKB: F1SI68 (UniProtKB/TrEMBL),   A0A8D1HRI4 (UniProtKB/TrEMBL),   A0A8D0PA96 (UniProtKB/TrEMBL),   A0A8D0VZ08 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000017047   ⟸   ENSSSCT00000017519
Protein Domains
BTB/POZ   Potassium channel tetramerisation-type BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016091 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015053569 UniProtKB/TrEMBL
  ENSSSCG00025077605 UniProtKB/TrEMBL
  ENSSSCG00030020171 UniProtKB/TrEMBL
  ENSSSCG00040034505 UniProtKB/TrEMBL
  ENSSSCG00045019521 UniProtKB/TrEMBL
  ENSSSCG00055007993 UniProtKB/TrEMBL
  ENSSSCG00060012764 UniProtKB/TrEMBL
  ENSSSCG00070023378 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017519 ENTREZGENE
  ENSSSCT00000017519.4 UniProtKB/TrEMBL
  ENSSSCT00015071347.1 UniProtKB/TrEMBL
  ENSSSCT00025107973.1 UniProtKB/TrEMBL
  ENSSSCT00030027885.1 UniProtKB/TrEMBL
  ENSSSCT00040046447.1 UniProtKB/TrEMBL
  ENSSSCT00045033229.1 UniProtKB/TrEMBL
  ENSSSCT00055015616.1 UniProtKB/TrEMBL
  ENSSSCT00060016760.1 UniProtKB/TrEMBL
  ENSSSCT00070046633.1 UniProtKB/TrEMBL
  ENSSSCT00070046636.1 UniProtKB/TrEMBL
InterPro KCTD18_C UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  T1-type_BTB UniProtKB/TrEMBL
KEGG Report ssc:100523334 UniProtKB/TrEMBL
NCBI Gene KCTD18 ENTREZGENE
PANTHER BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD18 UniProtKB/TrEMBL
  POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING UniProtKB/TrEMBL
Pfam BTB_2 UniProtKB/TrEMBL
  KCTD18_C UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/TrEMBL
UniProt A0A4X1VCJ7_PIG UniProtKB/TrEMBL
  A0A8D0PA96 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0VZ08 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1HRI4 ENTREZGENE, UniProtKB/TrEMBL
  F1SI68 ENTREZGENE, UniProtKB/TrEMBL