MIR30C-2 (microRNA mir-30c-2) - Rat Genome Database

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Gene: MIR30C-2 (microRNA mir-30c-2) Sus scrofa
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Symbol: MIR30C-2 (Ensembl: ssc-mir-30c-2)
Name: microRNA mir-30c-2 (Ensembl:ssc-mir-30c-2)
RGD ID: 13998808
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA 30c-2; MIR30C; ssc-mir-30c; ssc-mir-30c-2
RGD Orthologs
Human
Mouse
Rat
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl151,383,782 - 51,383,861 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1151,383,782 - 51,383,861 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2157,721,688 - 57,721,767 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:15885146   PMID:16381832   PMID:19196471   PMID:19917043   PMID:20180025   PMID:21312241   PMID:24499489   PMID:30382935  


Genomics

Comparative Map Data
MIR30C-2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl151,383,782 - 51,383,861 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1151,383,782 - 51,383,861 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2157,721,688 - 57,721,767 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MIR30C2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38671,376,960 - 71,377,031 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl671,376,960 - 71,377,031 (-)EnsemblGRCh38hg38GRCh38
GRCh37672,086,663 - 72,086,734 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36672,143,383 - 72,143,454 (-)NCBINCBI36Build 36hg18NCBI36
Celera672,475,116 - 72,475,187 (-)NCBICelera
Cytogenetic Map6q13NCBI
HuRef669,285,020 - 69,285,091 (-)NCBIHuRef
CHM1_1672,252,905 - 72,252,976 (-)NCBICHM1_1
T2T-CHM13v2.0672,557,564 - 72,557,635 (-)NCBIT2T-CHM13v2.0
Mir30c-2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39123,330,782 - 23,330,865 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl123,330,782 - 23,330,865 (+)EnsemblGRCm39 Ensembl
GRCm38123,291,701 - 23,291,784 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl123,291,701 - 23,291,784 (+)EnsemblGRCm38mm10GRCm38
MGSCv37123,298,540 - 23,298,623 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera123,141,402 - 23,141,485 (+)NCBICelera
Cytogenetic Map1A5NCBI
cM Map19.54NCBI
Mir30c2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8933,253,682 - 33,253,765 (+)NCBIGRCr8
mRatBN7.2925,757,342 - 25,757,425 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl925,757,342 - 25,757,425 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx934,260,256 - 34,260,339 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0939,383,558 - 39,383,641 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0937,688,313 - 37,688,396 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0929,562,376 - 29,562,459 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl929,562,376 - 29,562,459 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0928,397,564 - 28,397,647 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera923,305,349 - 23,305,432 (+)NCBICelera
Cytogenetic Map9q13NCBI
MIR30C-2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11233,757,899 - 33,757,960 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1233,757,890 - 33,757,969 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1233,616,846 - 33,616,907 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01234,298,119 - 34,298,180 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1234,298,110 - 34,298,189 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11233,833,565 - 33,833,626 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01233,871,623 - 33,871,684 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01233,982,418 - 33,982,479 (-)NCBIUU_Cfam_GSD_1.0


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system
High
Medium 2 1 2 4 2 1
Low 3 1 2 1 1 15
Below cutoff

Sequence


RefSeq Acc Id: ENSSSCT00000021115
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl151,383,782 - 51,383,861 (-)Ensembl
RefSeq Acc Id: NR_038510
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1151,383,782 - 51,383,861 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000019520 Ensembl, ENTREZGENE
Ensembl Transcript ENSSSCT00000021115 ENTREZGENE
miRBase MI0002461 ENTREZGENE
NCBI Gene MIR30C-2 ENTREZGENE
RNAcentral URS000019907A RNACentral
  URS0000527228 RNACentral
  URS00007E46D5 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR30C-2  microRNA mir-30c-2    microRNA 30c-2  Symbol and/or name change 5135510 APPROVED