S100A6 (S100 calcium binding protein A6) - Rat Genome Database

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Gene: S100A6 (S100 calcium binding protein A6) Sus scrofa
Analyze
Symbol: S100A6
Name: S100 calcium binding protein A6
RGD ID: 13996444
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); monoatomic ion transmembrane transporter activity (ortholog); INVOLVED IN cellular response to virus; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN cytoplasm; nucleus; cytoplasmic side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: calcyclin; protein S100-A6
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl496,098,525 - 96,099,684 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1496,098,264 - 96,099,686 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:15679890   PMID:16971568   PMID:17145712   PMID:22301074   PMID:25480733   PMID:30032202  


Genomics

Comparative Map Data
S100A6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl496,098,525 - 96,099,684 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1496,098,264 - 96,099,686 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
S100A6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381153,534,599 - 153,535,991 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1153,534,599 - 153,536,244 (-)EnsemblGRCh38hg38GRCh38
GRCh371153,507,075 - 153,508,467 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361151,773,700 - 151,775,341 (-)NCBINCBI36Build 36hg18NCBI36
Build 341150,320,148 - 150,321,790NCBI
Celera1126,578,337 - 126,579,978 (-)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1124,870,339 - 124,871,980 (-)NCBIHuRef
CHM1_11154,903,041 - 154,904,682 (-)NCBICHM1_1
T2T-CHM13v2.01152,671,855 - 152,673,247 (-)NCBIT2T-CHM13v2.0
S100a6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39390,520,491 - 90,531,797 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl390,520,189 - 90,531,488 (+)EnsemblGRCm39 Ensembl
GRCm38390,612,894 - 90,614,414 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl390,612,882 - 90,624,181 (+)EnsemblGRCm38mm10GRCm38
MGSCv37390,416,816 - 90,418,336 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36390,699,111 - 90,700,341 (+)NCBIMGSCv36mm8
Celera390,654,296 - 90,655,816 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map339.35NCBI
S100a6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82178,398,189 - 178,399,763 (+)NCBIGRCr8
mRatBN7.22176,100,619 - 176,102,181 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2176,100,899 - 176,102,180 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2183,241,176 - 183,242,401 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02181,263,442 - 181,264,667 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02175,863,300 - 175,864,525 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02190,007,013 - 190,008,512 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2190,007,216 - 190,008,511 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02209,441,142 - 209,442,605 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42182,895,080 - 182,896,305 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12182,845,185 - 182,846,411 (+)NCBI
Celera2170,035,682 - 170,036,907 (+)NCBICelera
Cytogenetic Map2q34NCBI
S100A6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2196,297,611 - 96,299,362 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1196,032,847 - 96,034,544 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01128,889,749 - 128,891,425 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11132,518,834 - 132,520,499 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1132,518,834 - 132,520,499 (-)Ensemblpanpan1.1panPan2
S100A6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1743,501,430 - 43,503,100 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl743,501,989 - 43,541,604 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha742,994,834 - 42,995,982 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0743,451,601 - 43,452,754 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1743,153,876 - 43,155,021 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0743,207,730 - 43,208,875 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0743,491,387 - 43,492,538 (+)NCBIUU_Cfam_GSD_1.0
S100a6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505824,316,803 - 24,317,471 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365803,347,152 - 3,348,105 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365803,347,185 - 3,347,878 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
S100A6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12010,267,708 - 10,269,361 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2010,267,556 - 10,269,405 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660389,659,199 - 9,660,869 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in S100A6
28 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 1 14 2 3 3
Low 4 3 4 2 9
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000030184   ⟹   ENSSSCP00000020154
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl496,098,525 - 96,099,684 (+)Ensembl
RefSeq Acc Id: NM_001044557   ⟹   NP_001038022
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1496,098,264 - 96,099,685 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021088752   ⟹   XP_020944411
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1496,098,271 - 96,099,686 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021088753   ⟹   XP_020944412
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1496,098,668 - 96,099,686 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001038022   ⟸   NM_001044557
- UniProtKB: Q2EN75 (UniProtKB/Swiss-Prot),   A0A8D1BF98 (UniProtKB/TrEMBL),   A0A8D1WLC3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020944411   ⟸   XM_021088752
- Peptide Label: isoform X1
- UniProtKB: A0A4X1VVF5 (UniProtKB/TrEMBL),   I3L7Z6 (UniProtKB/TrEMBL),   A0A8D1BF98 (UniProtKB/TrEMBL),   A0A8D1WLC3 (UniProtKB/TrEMBL),   A0A4X1W002 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020944412   ⟸   XM_021088753
- Peptide Label: isoform X1
- UniProtKB: A0A4X1VVF5 (UniProtKB/TrEMBL),   I3L7Z6 (UniProtKB/TrEMBL),   A0A8D1BF98 (UniProtKB/TrEMBL),   A0A8D1WLC3 (UniProtKB/TrEMBL),   A0A4X1W002 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000020154   ⟸   ENSSSCT00000030184
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000021084 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005017442 UniProtKB/TrEMBL
  ENSSSCG00015022077 UniProtKB/TrEMBL
  ENSSSCG00025019381 UniProtKB/TrEMBL
  ENSSSCG00030057331 UniProtKB/TrEMBL
  ENSSSCG00035079907 UniProtKB/TrEMBL
  ENSSSCG00040029801 UniProtKB/TrEMBL
  ENSSSCG00045018100 UniProtKB/TrEMBL
  ENSSSCG00050019906 UniProtKB/Swiss-Prot
  ENSSSCG00055000005 UniProtKB/TrEMBL
  ENSSSCG00060070161 UniProtKB/TrEMBL
  ENSSSCG00065076468 UniProtKB/TrEMBL
  ENSSSCG00070027985 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000030184 ENTREZGENE
  ENSSSCT00000030184.4 UniProtKB/TrEMBL
  ENSSSCT00005027511.1 UniProtKB/TrEMBL
  ENSSSCT00015029274.1 UniProtKB/TrEMBL
  ENSSSCT00025026269.1 UniProtKB/TrEMBL
  ENSSSCT00030079938.1 UniProtKB/TrEMBL
  ENSSSCT00030079962.1 UniProtKB/TrEMBL
  ENSSSCT00035109326.1 UniProtKB/TrEMBL
  ENSSSCT00035109339.1 UniProtKB/TrEMBL
  ENSSSCT00040040078.1 UniProtKB/TrEMBL
  ENSSSCT00045030843.1 UniProtKB/TrEMBL
  ENSSSCT00050026870.1 UniProtKB/Swiss-Prot
  ENSSSCT00055000006.1 UniProtKB/TrEMBL
  ENSSSCT00060095749.1 UniProtKB/TrEMBL
  ENSSSCT00065105614.1 UniProtKB/TrEMBL
  ENSSSCT00070056161.1 UniProtKB/TrEMBL
  ENSSSCT00070056162.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S-100A6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S100/CaBP-9k_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S100_Ca-bd_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:733608 UniProtKB/Swiss-Prot
NCBI Gene S100A6 ENTREZGENE
PANTHER PROTEIN S100-A6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S100 CALCIUM-BINDING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam S_100 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S100_CABP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART EFh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S_100 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A4X1VVF5 ENTREZGENE
  A0A4X1W002 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1BF98 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1WLC3 ENTREZGENE, UniProtKB/TrEMBL
  I3L7Z6 ENTREZGENE, UniProtKB/TrEMBL
  Q2EN75 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A0A4X1VVF5 UniProtKB/TrEMBL
VGNC ID VGNC:92545 ENTREZGENE