PVR (PVR cell adhesion molecule) - Rat Genome Database

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Gene: PVR (PVR cell adhesion molecule) Sus scrofa
Analyze
Symbol: PVR
Name: PVR cell adhesion molecule
RGD ID: 13973926
Description: ENCODES a protein that exhibits dynein light chain binding (ortholog); virus receptor activity (ortholog); INVOLVED IN cell migration (ortholog); cell-cell adhesion (ortholog); positive regulation of natural killer cell mediated cytotoxicity (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); ethylmalonic encephalopathy (ortholog); orofacial cleft 1 (ortholog); FOUND IN cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100525346; poliovirus receptor homolog
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1651,161,320 - 51,178,464 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,020,048 - 47,038,024 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PVR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1651,161,320 - 51,178,464 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,020,048 - 47,038,024 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PVR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381944,643,910 - 44,666,162 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1944,643,798 - 44,666,162 (+)EnsemblGRCh38hg38GRCh38
GRCh371945,147,210 - 45,169,430 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361949,839,066 - 49,858,690 (+)NCBINCBI36Build 36hg18NCBI36
Build 341949,839,065 - 49,858,689NCBI
Celera1941,951,144 - 41,973,471 (+)NCBICelera
Cytogenetic Map19q13.31NCBI
HuRef1941,579,341 - 41,601,754 (+)NCBIHuRef
CHM1_11945,149,748 - 45,172,111 (+)NCBICHM1_1
T2T-CHM13v2.01947,468,632 - 47,490,944 (+)NCBIT2T-CHM13v2.0
Pvr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39719,637,503 - 19,655,068 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl719,637,503 - 19,655,085 (-)EnsemblGRCm39 Ensembl
GRCm38719,903,578 - 19,921,143 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,903,578 - 19,921,160 (-)EnsemblGRCm38mm10GRCm38
MGSCv37720,488,927 - 20,506,492 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36719,062,100 - 19,079,613 (-)NCBIMGSCv36mm8
Celera717,310,717 - 17,327,912 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.95NCBI
Pvr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,689,235 - 88,704,641 (-)NCBIGRCr8
mRatBN7.2179,561,294 - 79,576,700 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl179,546,879 - 79,576,715 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx184,955,696 - 84,971,120 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0193,505,836 - 93,521,203 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,710,813 - 86,726,237 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0180,820,306 - 80,835,712 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,820,050 - 80,835,701 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0182,085,555 - 82,100,961 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4179,213,654 - 79,229,063 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1179,291,499 - 79,307,163 (-)NCBI
Celera174,018,461 - 74,033,867 (-)NCBICelera
RH 3.4 Map1819.8RGD
Cytogenetic Map1q21NCBI
PVR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22050,803,497 - 50,823,257 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11952,675,478 - 52,695,282 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01941,592,042 - 41,614,397 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11950,196,980 - 50,216,832 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1950,196,980 - 50,217,006 (+)Ensemblpanpan1.1panPan2
PVR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11110,692,906 - 110,713,209 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1110,697,911 - 110,754,296 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1110,175,812 - 110,196,115 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01111,257,096 - 111,277,399 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1111,261,295 - 111,277,390 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11110,898,742 - 110,919,041 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01110,534,429 - 110,554,736 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01111,404,145 - 111,424,445 (-)NCBIUU_Cfam_GSD_1.0
Pvr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,009,613 - 17,022,236 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367061,356,690 - 1,369,547 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103234825
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1638,127,864 - 38,141,612 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023667612773 - 12,781 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in PVR
283 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 9 3 3 5 2 23 3 3
Below cutoff 1 1 2

Sequence


Reference Sequences
RefSeq Acc Id: XM_005653282   ⟹   XP_005653339
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1651,161,322 - 51,178,464 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005653283   ⟹   XP_005653340
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1651,161,320 - 51,176,182 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021094514   ⟹   XP_020950173
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1651,161,322 - 51,178,464 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021094515   ⟹   XP_020950174
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1651,161,322 - 51,178,464 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005653340   ⟸   XM_005653283
- Peptide Label: isoform X2
- UniProtKB: A0A4X1W2M6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005653339   ⟸   XM_005653282
- Peptide Label: isoform X1
- UniProtKB: A0A4X1VX78 (UniProtKB/TrEMBL),   A0A5K1UL34 (UniProtKB/TrEMBL),   A0A8D1RXF7 (UniProtKB/TrEMBL),   A0A8D0KEH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020950173   ⟸   XM_021094514
- Peptide Label: isoform X1
- UniProtKB: A0A4X1VX78 (UniProtKB/TrEMBL),   A0A5K1UL34 (UniProtKB/TrEMBL),   A0A8D1RXF7 (UniProtKB/TrEMBL),   A0A8D0KEH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020950174   ⟸   XM_021094515
- Peptide Label: isoform X1
- UniProtKB: A0A4X1VX78 (UniProtKB/TrEMBL),   A0A5K1UL34 (UniProtKB/TrEMBL),   A0A8D1RXF7 (UniProtKB/TrEMBL),   A0A8D0KEH8 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000003079 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005041236 UniProtKB/TrEMBL
  ENSSSCG00025051468 UniProtKB/TrEMBL
  ENSSSCG00035001772 UniProtKB/TrEMBL
  ENSSSCG00040025517 UniProtKB/TrEMBL
  ENSSSCG00045022188 UniProtKB/TrEMBL
  ENSSSCG00055025419 UniProtKB/TrEMBL
  ENSSSCG00065075585 UniProtKB/TrEMBL
  ENSSSCG00070028408 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000033534.4 UniProtKB/TrEMBL
  ENSSSCT00000084094 ENTREZGENE
  ENSSSCT00000084094.1 UniProtKB/TrEMBL
  ENSSSCT00005066258.1 UniProtKB/TrEMBL
  ENSSSCT00025070540.1 UniProtKB/TrEMBL
  ENSSSCT00035002200.1 UniProtKB/TrEMBL
  ENSSSCT00040034014.1 UniProtKB/TrEMBL
  ENSSSCT00045038091.1 UniProtKB/TrEMBL
  ENSSSCT00055050334.1 UniProtKB/TrEMBL
  ENSSSCT00065104319.1 UniProtKB/TrEMBL
  ENSSSCT00070056955.1 UniProtKB/TrEMBL
  ENSSSCT00070056957.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
KEGG Report ssc:100525346 UniProtKB/TrEMBL
NCBI Gene LOC100525346 ENTREZGENE
PANTHER NECTIN-2 UniProtKB/TrEMBL
  NECTIN-2 UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A4X1VX78 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1W2M6 ENTREZGENE, UniProtKB/TrEMBL
  A0A5K1UL34 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0KEH8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1RXF7 ENTREZGENE, UniProtKB/TrEMBL
  K7GR94_PIG UniProtKB/TrEMBL
UniProt Secondary M3VK20 UniProtKB/TrEMBL
VGNC ID VGNC:98546 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-05-04 PVR  PVR cell adhesion molecule  LOC100525346  poliovirus receptor homolog  Symbol and/or name change 19259463 PROVISIONAL