RGS14 (regulator of G protein signaling 14)

Gene: RGS14 (regulator of G protein signaling 14) Sus scrofa

Analyze

Symbol:

RGS14

Name:

regulator of G protein signaling 14

RGD ID:

13964865

Description:

ENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); protein kinase binding (ortholog); signaling receptor complex adaptor activity (ortholog); INVOLVED IN mitotic cell cycle (ortholog); negative regulation of ERK1 and ERK2 cascade (ortholog); platelet-derived growth factor receptor signaling pathway (ortholog); ASSOCIATED WITH Chromosome 5, Trisomy 5q (ortholog); Ehlers-Danlos syndrome dermatosparaxis type (ortholog); Ehlers-Danlos syndrome spondylodysplastic type 2 (ortholog); FOUND IN dendrite (ortholog); glutamatergic synapse (ortholog); postsynaptic density (ortholog); INTERACTS WITH deoxynivalenol

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

regulator of G-protein signaling 14

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	80,574,415 - 80,590,003 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	80,574,411 - 80,589,998 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	82,278,839 - 82,294,432 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chromosome 5, Trisomy 5q (ISO)

Ehlers-Danlos syndrome dermatosparaxis type (ISO)

Ehlers-Danlos syndrome spondylodysplastic type 2 (ISO)

Marfanoid Mental Retardation Syndrome, Autosomal (ISO)

nephrolithiasis (ISO)

Sotos syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

deoxynivalenol (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell division (IBA,IEA)

chromosome segregation (IEA)

learning (IEA)

long-term memory (IEA)

long-term synaptic potentiation (IEA)

mitotic cell cycle (IEA,ISO)

modulation of chemical synaptic transmission (IEA)

negative regulation of ERK1 and ERK2 cascade (ISO)

negative regulation of G protein-coupled receptor signaling pathway (IEA)

negative regulation of synaptic plasticity (IEA)

nucleocytoplasmic transport (IEA)

platelet-derived growth factor receptor signaling pathway (ISO)

positive regulation of neurogenesis (ISO)

regulation of G protein-coupled receptor signaling pathway (IBA,IEA,ISO)

response to oxidative stress (ISO)

signal transduction (IEA)

spindle organization (IBA,IEA)

visual learning (ISO)

zygote asymmetric cell division (IEA)

Cellular Component

centrosome (IEA)

cytoplasm (IBA,IEA)

dendrite (IEA,ISO)

dendritic spine (IEA)

glutamatergic synapse (IEA,ISO)

nuclear body (IEA)

nucleus (IBA,IEA)

plasma membrane (IBA,IEA)

postsynaptic density (IEA,ISO)

spindle (IEA)

spindle pole (ISO)

Molecular Function

G-protein alpha-subunit binding (IEA,ISO)

GDP-dissociation inhibitor activity (IEA)

GTPase activating protein binding (IEA)

GTPase activator activity (IBA,IEA)

microtubule binding (IEA)

protein binding (ISO)

protein kinase binding (ISO)

signaling receptor complex adaptor activity (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

RGS14
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	80,574,415 - 80,590,003 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	80,574,411 - 80,589,998 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	82,278,839 - 82,294,432 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RGS14
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	177,357,924 - 177,372,596 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	177,357,924 - 177,372,596 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	176,784,925 - 176,799,597 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	176,717,450 - 176,732,205 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	176,717,449 - 176,732,204	NCBI
Celera	5	171,701,669 - 171,716,413 (-)	NCBI		Celera
Cytogenetic Map	5	q35.3	NCBI
HuRef	5	171,705,499 - 171,720,237 (+)	NCBI		HuRef
CHM1_1	5	176,217,893 - 176,232,649 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	177,901,146 - 177,915,812 (+)	NCBI		T2T-CHM13v2.0

Rgs14
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	55,517,269 - 55,532,504 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	55,517,545 - 55,532,500 (+)	Ensembl		GRCm39 Ensembl
GRCm38	13	55,369,732 - 55,384,687 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	55,369,732 - 55,384,687 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	55,471,093 - 55,486,048 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	54,849,935 - 54,864,851 (+)	NCBI		MGSCv36	mm8
MGSCv36	13	55,379,393 - 55,394,309 (+)	NCBI		MGSCv36	mm8
Cytogenetic Map	13	B1	NCBI
cM Map	13	29.8	NCBI

Rgs14
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	9,254,112 - 9,268,233 (-)	NCBI		GRCr8
mRatBN7.2	17	9,248,982 - 9,263,104 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	9,249,019 - 9,263,104 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	9,265,278 - 9,279,405 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	10,795,224 - 10,809,305 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	9,261,669 - 9,275,796 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	9,777,925 - 9,792,007 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	9,777,842 - 9,792,007 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	11,887,270 - 11,901,352 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	15,293,100 - 15,307,162 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	17	15,293,099 - 15,307,162 (-)	NCBI
Celera	17	9,327,534 - 9,341,623 (-)	NCBI		Celera
Cytogenetic Map	17	p14	NCBI

Rgs14
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	29,602,820 - 29,616,210 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955408	29,602,654 - 29,616,793 (+)	NCBI	ChiLan1.0	ChiLan1.0

RGS14
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	172,441,892 - 172,456,648 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	170,581,431 - 170,596,187 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	172,659,323 - 172,674,084 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	179,721,876 - 179,736,608 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	179,721,876 - 179,739,453 (+)	Ensembl	panpan1.1		panPan2

RGS14
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	35,984,970 - 35,999,386 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	35,985,132 - 35,999,294 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	35,952,393 - 35,966,792 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	36,351,200 - 36,365,605 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	36,310,038 - 36,365,601 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	36,176,431 - 36,190,828 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	36,362,626 - 36,377,029 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	36,871,876 - 36,886,282 (-)	NCBI		UU_Cfam_GSD_1.0

Rgs14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	122,617,771 - 122,633,949 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936597	1,643,616 - 1,658,638 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936597	1,650,480 - 1,658,823 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RGS14
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	79,370,320 - 79,385,355 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	79,370,087 - 79,387,192 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666075	10,559,155 - 10,573,950 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rgs14
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	12,707,825 - 12,723,279 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624733	12,705,392 - 12,722,919 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in RGS14
234 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium						3	1
Low	10	2		5	1	13	1	1	3
Below cutoff		2	3		1	7		2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005661452	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013994866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK394244	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU915382	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01027004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000015336 ⟹ ENSSSCP00000014928

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	2	80,574,416 - 80,590,003 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000100663 ⟹ ENSSSCP00000074920

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	2	80,574,415 - 80,589,890 (-)	Ensembl

RefSeq Acc Id:

XM_005661452 ⟹ XP_005661509

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	2	80,574,411 - 80,589,998 (-)	NCBI

Sequence:

show sequence

TGTAGGAAGAAGCATTCGCTCTCTTAGACCTTGCTTCTTTCTGTGGTTCGGTTTCTATAGAGAC
GCTTCCTGTGGCAGAGAAAAGAGGTAGTGAGCTGGTGTTTCAGGATGTGAGGGCCCGCAGGAGC
GGAGCTGGGCTCTCTCTGCCGCCTGCCCATCACCGTGAAAGCTCTGACCGGCGCTGCCCGAAGT
CCCCATGGTGGGCGCCTCCCGTGGCAGGGACCCGTGAAGAGCAGCGGCATGCCGGGGAAGCCCA
AGCACCTGGGCGTCCCCAACGGACGCATGGTTCTGGCTGTCTCTGATGGAGAGCTAAGCAGCAC
GGCAGGGCCCCAGGGCCAGGGCGAGGGCCGAGGCAGCTCCCTCAGCATCCACAGCCTCCCCAGT
GGCCCCAGCAGCCCCTACCCCACCGAGGAGCAGCCTGTGGCCAGCTGGGGCCTGTCCTTCGAGC
GGCTGCTGCAGGACCCGCTGGGCCTGGCTTACTTCACTGAGTTCCTGAAGAAGGAGTTCAGTGC
CGAGAACGTGACTTTCTGGAAGGCCTGCGAGCGCTTCCAGCAGATCCCAGCCAGCGACACCCAG
CAGTTAGCTCAGGAGGCCCGCAACATCTACCAGGAGTTCCTGTCCAGCCAGGCGCTGAGCCCGG
TGAATATCGACCGGCAGGCCTGGCTCGGCGAGGAGGTGCTGGCGGAGCCCCGACCGGACATGTT
CCGGGAACAGCAGCTTCAGATCTTCAACTTGATGAAGTTCGACAGCTATGCGCGCTTCGTCAAA
TCCCCGATGTACCGCGAGTGCCTCCTAGCGGAGGCCGAGGGTCGCCCCCTGCGGGAACCTGGAT
CCTCGCGCCTCGGCAGCCCTGAAGCCACAAGGAAGAAACCTAAGCTGAAGCCTGGGAAGTCGCT
GCCGCTGGGTGTGGAGGAGTTGGGGCAGCAGCCGCAGGCTGAGGGCCCTGGGGGCCGCCCTCTC
CGCAAGTCCTTCCGCAAGGAACAAGGTGGGGCAGCAAATTCAGCCTTGCGCAGAGAGTCTCAGG
GATCTCTCAACTCCTCCGCCAGCTTGGACCTCGGCTTCCTTGCCTTTGTCAGCAGCAAGTCTGA
AAGCCACCGGAAGAGCCTTGGGAGCTCAGAAGGTGAGAGTGAAAGCCGGCCAGGGAAGTACTGC
TGCGTGTACCTGCCTGATGGCACAGCCTCCTTGGCCCTAGCCCGACCTGGCCTCACTATCCGTG
ACATGCTGGCAGGCATCTGTGAGAAACGAGGCCTCTCTCTACCTGACATCAAGGTCTACCTGGT
GGGCAATGAGCAGAAGGCCCTGGTCTTGGATCAGGACTGCACCGTGCTGGCGGACCAGGAAGTG
CGACTGGAGAACAGGATCACCTTCGAGCTGGAGTTGGCGGCGCTGGAGCGCGTGGTGCGGATCT
CCGCCAAGCCCACCAAGCGGCTGCAGGACGCGCTGCAGCCCATCCTGGCGAAGCATGGCCTCAG
CCCGCAACAGGTGGCGCTGCGCCTGCCAGGTGAGAAGCAGCCGCTGGATCTAGGGAAGCTGGTG
AGCTCCGTGGCGGCCCAGAGACTGGTGTTGGACACTCTCCCAGGTGTGAAGATCCCTGAAGCTG
GCGACGTACCCCCCTGCCGCAGCCAGGGTGGCCCCCCCAGGATCCAGGACAAAGCCACCCACCC
CCCTTCACAGTCCCTGAACTCACTGGCCCAGACATCCAGTAGTATCACTGGGAAGCGGCAGACC
TGTGACATTGAAGGCCTGGTGGAGCTGTTGAACCGGGTGCAGAGCAGCGGAGCCCATGATCAGA
GGGGCCTTCTGCGCAAAGAGGACCTGGTGCTTCCAGAATTTCTGCAGCTGCCTGTCCAAGGAAA
TAACTCCCAGGAGGCCCCAGCACAGACTGAATCAGCGGCCCAGCCTAAGGGGGCCCCCTCAGAC
TCCACTGCCCACTCAGCCCTCTGACAGCTGCCCAGAAGTCCAAGCCAGCTGCATGGCACCTGGC
GGGCCAAGCATGCCACGGGCCCGCTCTGCATGCCCTGTCTGTGCCATGAATATCCCTGGCCCCT
TCCTGCCACGGGCGGGCCCGCAGGAGGAGCTGGGAGAGGGTGGAGAGGGGACTCAGAGGAGTGA
CACTCCACGGCGGCCACCACATGATCCCTTACAGGCTTGCTCACCCATCCCCCGCCGCCACGCC
ACAGCAGGGAGGTGGGCCTAGTTCTCAGTGCAGGTGTGCCCAACACGGAGGGATGGCGTTGGCA
GTGCCAGCCTCCCCACCATGTGTCAGCTTTCAGCTGGGAGCAGGAGGAGGGGCTGGTCCCTCCT
AGAGGAGCTGGAATGAGCAAGGCCTGGGGGTGCAGGCAGGCAGCCCCTCCCTCTACCCACAGAG
ACACAACTGGAATTAAGGATTTTGCAGTGGGCTTGGGACAGCTAGATTTGTCCTGAATGTATAT
TGTTATAATGATAATTATTATTATTCTGCCATGAGGCATGTTCCTTGTGCGCCACCCCTACCCC
CCAAACTGCACTGCCTTTGTCACCAAGGTCAGTGCCAGGAAGTTCTTGGGGACCTCAGGATGTG
CCCCCCTGGCTTCCTGTTGTCAGAACCTCTCTTCCTGACTGCACAGAGTCATGGGTGTGAGTGT
GAGAGAGACAAAGACAGAGACAGCCCAAGAGAAGGAGGGAGGGAAAGAGGAAGCGGGGGAGGGA
GGGAGGAAGGCAGGGGAGGGGTAGATCCCTCTGGAGAGCTAGGCCTCCGTCGGTGTCACTGTGC
TGTTCCTTGATCTCTGGATCCGAGTGCAGTGTTTGGTCACGGTGCTCTGCTTCTGCTCGGGGCT
GAGTGTGACTCTGTAGACATGGTGCTGGGCTCCTATGGATGAATCAAAGGCCTTGAGGAGAGCG
CTGGTCTTCGTGGCAGGGGGCAGGGGGAAGTTCTGCCCCTTGCCTGCTTTGGCTGTGTAATCTC
TGTCCCCAGGAGGCAGCCAGGGAAGCCTGGAGCCCCTGTGGGAAGGGGGAGCAGAGAAGACCCC
AGACTGAGGGCCCCAACCTGCAGGCAGAGAAGCCAGACTTAGTGGTTTAGAAGCCAGACTAAGC
CACTAAGTGCCCAGACTGCTGTGACAGAGGAAACCAGGGAATGCAGGAGCCTTGAGAAGGAACC
TGGGGAGTGAGGGGCCCACTTGACCACCCTCAACAGGTCAGGCTCTCTTCCCCAGGCCAGCTCT
GCACTTGCTGTCCCTCGTCCACCCCCTATCTTATAACTGGGTCCTGAAATTTGGGGGAGAGAAC
GTGAGAAAAAAATTGCTGTCTAAAACCTGTAAGAGGGTCCTCACCAGAACCTGACCACGTTGGC
ACCCTGATCTTGGACTTCTGACCTCTAGAACTCTGAGAAATAAAGTTTTTTGTTGTTTACAA

hide sequence

RefSeq Acc Id:

XM_013994866 ⟹ XP_013850320

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	2	80,574,411 - 80,589,957 (-)	NCBI

Sequence:

show sequence

TGTGGTTCGGTTTCTATAGAGACGCTTCCTGTGGCAGAGAAAAGAGGTAGTGAGCTGGTGTTTC
AGGATGTGAGGGCCCGCAGGAGCGGAGCTGGGCTCTCTCTGCCGCCTGCCCATCACCGTGAAAG
CTCTGACCGGCGCTGCCCGAAGTCCCCATGGTGGGCGCCTCCCGTGGCAGGGACCCGTGAAGAG
CAGCGGCATGCCGGGGAAGCCCAAGCACCTGGGCGTCCCCAACGGACGCATGGTTCTGGCTGTC
TCTGATGGAGGAGTTCCTGAAGAAGGAGTTCAGTGCCGAGAACGTGACTTTCTGGAAGGCCTGC
GAGCGCTTCCAGCAGATCCCAGCCAGCGACACCCAGCAGTTAGCTCAGGAGGCCCGCAACATCT
ACCAGGAGTTCCTGTCCAGCCAGGCGCTGAGCCCGGTGAATATCGACCGGCAGGCCTGGCTCGG
CGAGGAGGTGCTGGCGGAGCCCCGACCGGACATGTTCCGGGAACAGCAGCTTCAGATCTTCAAC
TTGATGAAGTTCGACAGCTATGCGCGCTTCGTCAAATCCCCGATGTACCGCGAGTGCCTCCTAG
CGGAGGCCGAGGGTCGCCCCCTGCGGGAACCTGGATCCTCGCGCCTCGGCAGCCCTGAAGCCAC
AAGGAAGAAACCTAAGCTGAAGCCTGGGAAGTCGCTGCCGCTGGGTGTGGAGGAGTTGGGGCAG
CAGCCGCAGGCTGAGGGCCCTGGGGGCCGCCCTCTCCGCAAGTCCTTCCGCAAGGAACAAGGTG
GGGCAGCAAATTCAGCCTTGCGCAGAGAGTCTCAGGGATCTCTCAACTCCTCCGCCAGCTTGGA
CCTCGGCTTCCTTGCCTTTGTCAGCAGCAAGTCTGAAAGCCACCGGAAGAGCCTTGGGAGCTCA
GAAGGTGAGAGTGAAAGCCGGCCAGGGAAGTACTGCTGCGTGTACCTGCCTGATGGCACAGCCT
CCTTGGCCCTAGCCCGACCTGGCCTCACTATCCGTGACATGCTGGCAGGCATCTGTGAGAAACG
AGGCCTCTCTCTACCTGACATCAAGGTCTACCTGGTGGGCAATGAGCAGAAGGCCCTGGTCTTG
GATCAGGACTGCACCGTGCTGGCGGACCAGGAAGTGCGACTGGAGAACAGGATCACCTTCGAGC
TGGAGTTGGCGGCGCTGGAGCGCGTGGTGCGGATCTCCGCCAAGCCCACCAAGCGGCTGCAGGA
CGCGCTGCAGCCCATCCTGGCGAAGCATGGCCTCAGCCCGCAACAGGTGGCGCTGCGCCTGCCA
GGTGAGAAGCAGCCGCTGGATCTAGGGAAGCTGGTGAGCTCCGTGGCGGCCCAGAGACTGGTGT
TGGACACTCTCCCAGGTGTGAAGATCCCTGAAGCTGGCGACGTACCCCCCTGCCGCAGCCAGGG
TGGCCCCCCCAGGATCCAGGACAAAGCCACCCACCCCCCTTCACAGTCCCTGAACTCACTGGCC
CAGACATCCAGTAGTATCACTGGGAAGCGGCAGACCTGTGACATTGAAGGCCTGGTGGAGCTGT
TGAACCGGGTGCAGAGCAGCGGAGCCCATGATCAGAGGGGCCTTCTGCGCAAAGAGGACCTGGT
GCTTCCAGAATTTCTGCAGCTGCCTGTCCAAGGAAATAACTCCCAGGAGGCCCCAGCACAGACT
GAATCAGCGGCCCAGCCTAAGGGGGCCCCCTCAGACTCCACTGCCCACTCAGCCCTCTGACAGC
TGCCCAGAAGTCCAAGCCAGCTGCATGGCACCTGGCGGGCCAAGCATGCCACGGGCCCGCTCTG
CATGCCCTGTCTGTGCCATGAATATCCCTGGCCCCTTCCTGCCACGGGCGGGCCCGCAGGAGGA
GCTGGGAGAGGGTGGAGAGGGGACTCAGAGGAGTGACACTCCACGGCGGCCACCACATGATCCC
TTACAGGCTTGCTCACCCATCCCCCGCCGCCACGCCACAGCAGGGAGGTGGGCCTAGTTCTCAG
TGCAGGTGTGCCCAACACGGAGGGATGGCGTTGGCAGTGCCAGCCTCCCCACCATGTGTCAGCT
TTCAGCTGGGAGCAGGAGGAGGGGCTGGTCCCTCCTAGAGGAGCTGGAATGAGCAAGGCCTGGG
GGTGCAGGCAGGCAGCCCCTCCCTCTACCCACAGAGACACAACTGGAATTAAGGATTTTGCAGT
GGGCTTGGGACAGCTAGATTTGTCCTGAATGTATATTGTTATAATGATAATTATTATTATTCTG
CCATGAGGCATGTTCCTTGTGCGCCACCCCTACCCCCCAAACTGCACTGCCTTTGTCACCAAGG
TCAGTGCCAGGAAGTTCTTGGGGACCTCAGGATGTGCCCCCCTGGCTTCCTGTTGTCAGAACCT
CTCTTCCTGACTGCACAGAGTCATGGGTGTGAGTGTGAGAGAGACAAAGACAGAGACAGCCCAA
GAGAAGGAGGGAGGGAAAGAGGAAGCGGGGGAGGGAGGGAGGAAGGCAGGGGAGGGGTAGATCC
CTCTGGAGAGCTAGGCCTCCGTCGGTGTCACTGTGCTGTTCCTTGATCTCTGGATCCGAGTGCA
GTGTTTGGTCACGGTGCTCTGCTTCTGCTCGGGGCTGAGTGTGACTCTGTAGACATGGTGCTGG
GCTCCTATGGATGAATCAAAGGCCTTGAGGAGAGCGCTGGTCTTCGTGGCAGGGGGCAGGGGGA
AGTTCTGCCCCTTGCCTGCTTTGGCTGTGTAATCTCTGTCCCCAGGAGGCAGCCAGGGAAGCCT
GGAGCCCCTGTGGGAAGGGGGAGCAGAGAAGACCCCAGACTGAGGGCCCCAACCTGCAGGCAGA
GAAGCCAGACTTAGTGGTTTAGAAGCCAGACTAAGCCACTAAGTGCCCAGACTGCTGTGACAGA
GGAAACCAGGGAATGCAGGAGCCTTGAGAAGGAACCTGGGGAGTGAGGGGCCCACTTGACCACC
CTCAACAGGTCAGGCTCTCTTCCCCAGGCCAGCTCTGCACTTGCTGTCCCTCGTCCACCCCCTA
TCTTATAACTGGGTCCTGAAATTTGGGGGAGAGAACGTGAGAAAAAAATTGCTGTCTAAAACCT
GTAAGAGGGTCCTCACCAGAACCTGACCACGTTGGCACCCTGATCTTGGACTTCTGACCTCTAG
AACTCTGAGAAATAAAGTTTTTTGTTGTTTACAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005661509	(Get FASTA)	NCBI Sequence Viewer
	XP_013850320	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000014928
	ENSSSCP00000014928.4
	ENSSSCP00000074920.1
	ENSSSCP00015019953.1
	ENSSSCP00015020092.1
	ENSSSCP00025040153.1
	ENSSSCP00030024723.1
	ENSSSCP00030024752.1
	ENSSSCP00035016734.1
	ENSSSCP00035016738.1
	ENSSSCP00035016742.1
	ENSSSCP00040032301.1
	ENSSSCP00045045237.1
	ENSSSCP00045045283.1
	ENSSSCP00045045326.1
	ENSSSCP00050032016.1
	ENSSSCP00055023977.1
	ENSSSCP00065042299.1
	ENSSSCP00065042318.1
	ENSSSCP00065042324.1
	ENSSSCP00070000678.1
	ENSSSCP00070000689.1

RefSeq Acc Id:	XP_005661509 ⟸ XM_005661452
- Peptide Label:	isoform X1
- UniProtKB:	A0A4X1SFA4 (UniProtKB/TrEMBL), F1S3D6 (UniProtKB/TrEMBL), A0A8D0WR97 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPGKPKHLGVPNGRMVLAVSDGELSSTAGPQGQGEGRGSSLSIHSLPSGPSSPYPTEEQPVASW GLSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTQQLAQEARNIYQEFLSS QALSPVNIDRQAWLGEEVLAEPRPDMFREQQLQIFNLMKFDSYARFVKSPMYRECLLAEAEGRP LREPGSSRLGSPEATRKKPKLKPGKSLPLGVEELGQQPQAEGPGGRPLRKSFRKEQGGAANSAL RRESQGSLNSSASLDLGFLAFVSSKSESHRKSLGSSEGESESRPGKYCCVYLPDGTASLALARP GLTIRDMLAGICEKRGLSLPDIKVYLVGNEQKALVLDQDCTVLADQEVRLENRITFELELAALE RVVRISAKPTKRLQDALQPILAKHGLSPQQVALRLPGEKQPLDLGKLVSSVAAQRLVLDTLPGV KIPEAGDVPPCRSQGGPPRIQDKATHPPSQSLNSLAQTSSSITGKRQTCDIEGLVELLNRVQSS GAHDQRGLLRKEDLVLPEFLQLPVQGNNSQEAPAQTESAAQPKGAPSDSTAHSAL hide sequence

RefSeq Acc Id:	XP_013850320 ⟸ XM_013994866
- Peptide Label:	isoform X2
- UniProtKB:	A0A8D0WR97 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEEFLKKEFSAENVTFWKACERFQQIPASDTQQLAQEARNIYQEFLSSQALSPVNIDRQAWLGE EVLAEPRPDMFREQQLQIFNLMKFDSYARFVKSPMYRECLLAEAEGRPLREPGSSRLGSPEATR KKPKLKPGKSLPLGVEELGQQPQAEGPGGRPLRKSFRKEQGGAANSALRRESQGSLNSSASLDL GFLAFVSSKSESHRKSLGSSEGESESRPGKYCCVYLPDGTASLALARPGLTIRDMLAGICEKRG LSLPDIKVYLVGNEQKALVLDQDCTVLADQEVRLENRITFELELAALERVVRISAKPTKRLQDA LQPILAKHGLSPQQVALRLPGEKQPLDLGKLVSSVAAQRLVLDTLPGVKIPEAGDVPPCRSQGG PPRIQDKATHPPSQSLNSLAQTSSSITGKRQTCDIEGLVELLNRVQSSGAHDQRGLLRKEDLVL PEFLQLPVQGNNSQEAPAQTESAAQPKGAPSDSTAHSAL hide sequence

RefSeq Acc Id:

ENSSSCP00000014928 ⟸ ENSSSCT00000015336

RefSeq Acc Id:

ENSSSCP00000074920 ⟸ ENSSSCT00000100663

Protein Domains

RBD RGS

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000014039	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015037515	UniProtKB/TrEMBL
	ENSSSCG00025066615	UniProtKB/TrEMBL
	ENSSSCG00030038883	UniProtKB/TrEMBL
	ENSSSCG00035031582	UniProtKB/TrEMBL
	ENSSSCG00040055550	UniProtKB/TrEMBL
	ENSSSCG00045037156	UniProtKB/TrEMBL
	ENSSSCG00050054463	UniProtKB/TrEMBL
	ENSSSCG00055015281	UniProtKB/TrEMBL
	ENSSSCG00065070338	UniProtKB/TrEMBL
	ENSSSCG00070000412	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000015336	ENTREZGENE
	ENSSSCT00000015336.5	UniProtKB/TrEMBL
	ENSSSCT00000100663.1	UniProtKB/TrEMBL
	ENSSSCT00015049992.1	UniProtKB/TrEMBL
	ENSSSCT00015050369.1	UniProtKB/TrEMBL
	ENSSSCT00025091483.1	UniProtKB/TrEMBL
	ENSSSCT00030054130.1	UniProtKB/TrEMBL
	ENSSSCT00030054187.1	UniProtKB/TrEMBL
	ENSSSCT00035041825.1	UniProtKB/TrEMBL
	ENSSSCT00035041841.1	UniProtKB/TrEMBL
	ENSSSCT00035041852.1	UniProtKB/TrEMBL
	ENSSSCT00040075265.1	UniProtKB/TrEMBL
	ENSSSCT00045064075.1	UniProtKB/TrEMBL
	ENSSSCT00045064136.1	UniProtKB/TrEMBL
	ENSSSCT00045064194.1	UniProtKB/TrEMBL
	ENSSSCT00050074275.1	UniProtKB/TrEMBL
	ENSSSCT00055030096.1	UniProtKB/TrEMBL
	ENSSSCT00065096620.1	UniProtKB/TrEMBL
	ENSSSCT00065096654.1	UniProtKB/TrEMBL
	ENSSSCT00065096666.1	UniProtKB/TrEMBL
	ENSSSCT00070000769.1	UniProtKB/TrEMBL
	ENSSSCT00070000782.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.167.10	UniProtKB/TrEMBL
	1.10.196.10	UniProtKB/TrEMBL
InterPro	GoLoco_motif	UniProtKB/TrEMBL
	RBD1_RGS14	UniProtKB/TrEMBL
	RBD2_RGS14	UniProtKB/TrEMBL
	RBD_dom	UniProtKB/TrEMBL
	RGS	UniProtKB/TrEMBL
	RGS10/12/14-like	UniProtKB/TrEMBL
	RGS14_RGS	UniProtKB/TrEMBL
	RGS_sf	UniProtKB/TrEMBL
	RGS_subdom1/3	UniProtKB/TrEMBL
	RGS_subdomain_2	UniProtKB/TrEMBL
	Ubiquitin-like_domsf	UniProtKB/TrEMBL
KEGG Report	ssc:100524790	UniProtKB/TrEMBL
NCBI Gene	RGS14	ENTREZGENE
PANTHER	PTHR45945:SF2	UniProtKB/TrEMBL
	REGULATOR OF G-PROTEIN SIGNALING LOCO	UniProtKB/TrEMBL
Pfam	GoLoco	UniProtKB/TrEMBL
	RBD	UniProtKB/TrEMBL
	RGS	UniProtKB/TrEMBL
PRINTS	RGSPROTEIN	UniProtKB/TrEMBL
PROSITE	GOLOCO	UniProtKB/TrEMBL
	RBD	UniProtKB/TrEMBL
	RGS	UniProtKB/TrEMBL
SMART	GoLoco	UniProtKB/TrEMBL
	RBD	UniProtKB/TrEMBL
	RGS	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48097	UniProtKB/TrEMBL
	SSF54236	UniProtKB/TrEMBL
UniProt	A0A4X1SFA4	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1SFS5_PIG	UniProtKB/TrEMBL
	A0A8D0WR97	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0WSZ2_PIG	UniProtKB/TrEMBL
	A0A8D1CSC6_PIG	UniProtKB/TrEMBL
	A0A8D1JA81_PIG	UniProtKB/TrEMBL
	A0A8W4F6U0_PIG	UniProtKB/TrEMBL
	F1S3D6	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:92261	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar