SLITRK2 (SLIT and NTRK like family member 2) - Rat Genome Database

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Gene: SLITRK2 (SLIT and NTRK like family member 2) Sus scrofa
Analyze
Symbol: SLITRK2
Name: SLIT and NTRK like family member 2
RGD ID: 13954847
Description: INVOLVED IN axonogenesis (ortholog); positive regulation of synapse assembly (ortholog); ASSOCIATED WITH autistic disorder (ortholog); intellectual disability (ortholog); non-syndromic X-linked intellectual developmental disorder 111 (ortholog); FOUND IN GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog); postsynaptic membrane (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SLIT and NTRK-like protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX118,830,086 - 118,834,307 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X118,826,531 - 118,837,134 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X136,058,440 - 136,066,217 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLITRK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX118,830,086 - 118,834,307 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X118,826,531 - 118,837,134 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X136,058,440 - 136,066,217 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLITRK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X145,817,829 - 145,829,856 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX145,817,829 - 145,829,856 (+)EnsemblGRCh38hg38GRCh38
GRCh37X144,899,347 - 144,911,374 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X144,707,042 - 144,715,052 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X144,604,895 - 144,612,904NCBI
CeleraX145,211,704 - 145,219,715 (+)NCBICelera
Cytogenetic MapXq27.3NCBI
HuRefX133,868,009 - 133,873,011 (+)NCBIHuRef
CHM1_1X144,810,593 - 144,818,604 (+)NCBICHM1_1
T2T-CHM13v2.0X144,074,860 - 144,086,894 (+)NCBIT2T-CHM13v2.0
Slitrk2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X65,692,535 - 65,705,008 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX65,692,924 - 65,704,999 (+)EnsemblGRCm39 Ensembl
GRCm38X66,648,951 - 66,661,402 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX66,649,318 - 66,661,393 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X63,902,493 - 63,914,577 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X62,913,672 - 62,917,110 (+)NCBIMGSCv36mm8
CeleraX55,108,474 - 55,120,526 (-)NCBICelera
Cytogenetic MapXA7.1NCBI
cM MapX34.81NCBI
Slitrk2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X150,287,418 - 150,299,832 (+)NCBIGRCr8
mRatBN7.2X145,246,448 - 145,259,983 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX145,246,460 - 145,271,220 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX147,450,931 - 147,454,371 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X150,975,813 - 150,979,253 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X148,525,830 - 148,529,270 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X151,099,388 - 151,111,816 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX151,103,576 - 151,107,016 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X151,095,085 - 151,108,778 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X152,668,556 - 152,671,996 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX141,105,289 - 141,108,729 (+)NCBICelera
Cytogenetic MapXq37NCBI
Slitrk2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955585479,798 - 486,363 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955585479,798 - 488,046 (-)NCBIChiLan1.0ChiLan1.0
SLITRK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X145,142,571 - 145,154,591 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X145,146,178 - 145,158,193 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X134,853,269 - 134,865,281 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X145,230,940 - 145,238,949 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX145,235,542 - 145,238,079 (+)Ensemblpanpan1.1panPan2
SLITRK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X114,576,526 - 114,584,471 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX114,581,070 - 114,583,607 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX100,438,007 - 100,445,960 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X116,597,295 - 116,605,248 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX116,597,210 - 116,609,305 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X113,722,487 - 113,730,439 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X115,929,087 - 115,937,038 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X115,659,264 - 115,667,220 (+)NCBIUU_Cfam_GSD_1.0
Slitrk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X112,644,721 - 112,656,767 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365132,961,983 - 2,966,439 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365132,961,842 - 2,969,938 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLITRK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X120,640,216 - 120,649,434 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX120,646,022 - 120,648,559 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606558,182,578 - 58,192,619 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slitrk2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248081,311,247 - 1,319,087 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248081,307,229 - 1,319,063 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLITRK2
120 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system nervous system
High
Medium 3
Low 1 3 20
Below cutoff 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000013911   ⟹   ENSSSCP00000013528
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX118,825,631 - 118,834,291 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000035609   ⟹   ENSSSCP00000030271
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX118,830,086 - 118,834,307 (+)Ensembl
RefSeq Acc Id: XM_013986477   ⟹   XP_013841931
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X118,827,143 - 118,837,134 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013986478   ⟹   XP_013841932
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X118,826,531 - 118,837,134 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021079739   ⟹   XP_020935398
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X118,827,142 - 118,837,134 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021079740   ⟹   XP_020935399
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X118,826,531 - 118,837,134 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_013841932   ⟸   XM_013986478
- UniProtKB: F1RQ61 (UniProtKB/TrEMBL),   A0A8D1DP42 (UniProtKB/TrEMBL),   A0A8D0VAY0 (UniProtKB/TrEMBL),   A0A8D0YC58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020935399   ⟸   XM_021079740
- UniProtKB: A0A8D1DP42 (UniProtKB/TrEMBL),   F1RQ61 (UniProtKB/TrEMBL),   A0A8D0VAY0 (UniProtKB/TrEMBL),   A0A8D0YC58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020935398   ⟸   XM_021079739
- UniProtKB: A0A8D1DP42 (UniProtKB/TrEMBL),   F1RQ61 (UniProtKB/TrEMBL),   A0A8D0VAY0 (UniProtKB/TrEMBL),   A0A8D0YC58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013841931   ⟸   XM_013986477
- UniProtKB: F1RQ61 (UniProtKB/TrEMBL),   A0A8D1DP42 (UniProtKB/TrEMBL),   A0A8D0VAY0 (UniProtKB/TrEMBL),   A0A8D0YC58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000030271   ⟸   ENSSSCT00000035609
RefSeq Acc Id: ENSSSCP00000013528   ⟸   ENSSSCT00000013911
Protein Domains
LRRCT   LRRNT


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000012724 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005045626 UniProtKB/TrEMBL
  ENSSSCG00015071206 UniProtKB/TrEMBL
  ENSSSCG00025075334 UniProtKB/TrEMBL
  ENSSSCG00030005171 UniProtKB/TrEMBL
  ENSSSCG00035002992 UniProtKB/TrEMBL
  ENSSSCG00040016668 UniProtKB/TrEMBL
  ENSSSCG00045021580 UniProtKB/TrEMBL
  ENSSSCG00050074174 UniProtKB/TrEMBL
  ENSSSCG00060005561 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000035609 ENTREZGENE
  ENSSSCT00000035609.4 UniProtKB/TrEMBL
  ENSSSCT00005073762.1 UniProtKB/TrEMBL
  ENSSSCT00015095488.1 UniProtKB/TrEMBL
  ENSSSCT00025103875.1 UniProtKB/TrEMBL
  ENSSSCT00025103901.1 UniProtKB/TrEMBL
  ENSSSCT00030007065.1 UniProtKB/TrEMBL
  ENSSSCT00030007068.1 UniProtKB/TrEMBL
  ENSSSCT00035003709.1 UniProtKB/TrEMBL
  ENSSSCT00035003711.1 UniProtKB/TrEMBL
  ENSSSCT00040022430.1 UniProtKB/TrEMBL
  ENSSSCT00040022439.1 UniProtKB/TrEMBL
  ENSSSCT00045036874.1 UniProtKB/TrEMBL
  ENSSSCT00045036916.1 UniProtKB/TrEMBL
  ENSSSCT00050101529.1 UniProtKB/TrEMBL
  ENSSSCT00050101535.1 UniProtKB/TrEMBL
  ENSSSCT00060007018.1 UniProtKB/TrEMBL
  ENSSSCT00060007019.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
  Slitrk UniProtKB/TrEMBL
KEGG Report ssc:100511615 UniProtKB/TrEMBL
NCBI Gene SLITRK2 ENTREZGENE
PANTHER PTHR45773 UniProtKB/TrEMBL
  SLIT AND NTRK-LIKE PROTEIN 2 UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
SMART LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A8D0VAY0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0YC58 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1DP42 ENTREZGENE, UniProtKB/TrEMBL
  F1RQ61 ENTREZGENE
UniProt Secondary F1RQ61 UniProtKB/TrEMBL
VGNC ID VGNC:93207 ENTREZGENE