DCAF7 (DDB1 and CUL4 associated factor 7) - Rat Genome Database

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Gene: DCAF7 (DDB1 and CUL4 associated factor 7) Sus scrofa
Analyze
Symbol: DCAF7
Name: DDB1 and CUL4 associated factor 7
RGD ID: 13950166
Description: ASSOCIATED WITH Craniofacial Abnormalities (ortholog); genetic disease (ortholog); myeloid leukemia associated with Down Syndrome (ortholog); FOUND IN Cul4-RING E3 ubiquitin ligase complex (inferred); cytosol (inferred); nuclear body (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DDB1- and CUL4-associated factor 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1215,319,593 - 15,350,976 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11215,319,578 - 15,350,996 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21215,306,441 - 15,337,836 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DCAF7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1215,319,593 - 15,350,976 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11215,319,578 - 15,350,996 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21215,306,441 - 15,337,836 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DCAF7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381763,550,477 - 63,594,266 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1763,550,222 - 63,594,286 (+)EnsemblGRCh38hg38GRCh38
GRCh371761,627,838 - 61,671,628 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361758,981,554 - 59,025,373 (+)NCBINCBI36Build 36hg18NCBI36
Celera1756,015,912 - 56,059,721 (+)NCBICelera
Cytogenetic Map17q23.3NCBI
HuRef1756,994,245 - 57,039,588 (+)NCBIHuRef
CHM1_11761,692,209 - 61,736,041 (+)NCBICHM1_1
T2T-CHM13v2.01764,421,091 - 64,464,885 (+)NCBIT2T-CHM13v2.0
Dcaf7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911105,927,698 - 105,950,150 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11105,927,698 - 105,950,150 (+)EnsemblGRCm39 Ensembl
GRCm3811106,036,872 - 106,059,324 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11106,036,872 - 106,059,324 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711105,898,186 - 105,920,638 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611105,852,962 - 105,875,414 (+)NCBIMGSCv36mm8
Celera11117,763,101 - 117,789,853 (+)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1168.89NCBI
Dcaf7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81091,473,900 - 91,496,080 (+)NCBIGRCr8
mRatBN7.21090,974,095 - 90,996,275 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1090,974,095 - 90,996,275 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1096,028,650 - 96,050,983 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01095,491,821 - 95,514,154 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01090,902,753 - 90,925,082 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01094,231,585 - 94,254,046 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1094,231,585 - 94,254,046 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01093,982,501 - 94,005,038 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41095,425,072 - 95,451,229 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11095,439,418 - 95,465,808 (+)NCBI
Celera1089,651,905 - 89,673,959 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
Dcaf7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554788,217,848 - 8,241,298 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554788,213,679 - 8,241,214 (-)NCBIChiLan1.0ChiLan1.0
DCAF7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21979,720,535 - 79,766,017 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11784,538,038 - 84,583,490 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01757,630,512 - 57,674,149 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11762,776,734 - 62,820,495 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1762,776,734 - 62,815,390 (+)Ensemblpanpan1.1panPan2
DCAF7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1911,562,676 - 11,593,419 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl911,562,686 - 11,593,391 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha912,523,164 - 12,553,530 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0913,226,220 - 13,256,707 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl913,226,124 - 13,256,707 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1912,170,815 - 12,201,270 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0915,330,674 - 15,361,032 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0915,333,654 - 15,364,013 (-)NCBIUU_Cfam_GSD_1.0
Dcaf7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560214,941,478 - 14,971,592 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365414,222,944 - 4,253,120 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365414,222,997 - 4,253,120 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCAF7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11657,695,930 - 57,731,444 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607728,309,828 - 28,345,335 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dcaf7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248491,065,834 - 1,098,039 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248491,066,194 - 1,098,039 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DCAF7
948 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1 3 2 12
Low 9 3 3 2 11 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000055375   ⟹   ENSSSCP00000056420
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1215,319,593 - 15,350,976 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000092098   ⟹   ENSSSCP00000079044
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1215,319,594 - 15,350,744 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000093143   ⟹   ENSSSCP00000081101
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1215,319,594 - 15,350,747 (-)Ensembl
RefSeq Acc Id: XM_003131294   ⟹   XP_003131342
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11215,319,578 - 15,350,996 (-)NCBI
Sequence:
RefSeq Acc Id: XR_306464
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11215,319,582 - 15,350,973 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003131342   ⟸   XM_003131294
- UniProtKB: A0A8D1X9S7 (UniProtKB/TrEMBL),   A0A287BIR3 (UniProtKB/TrEMBL),   A0A4X1T4J1 (UniProtKB/TrEMBL),   A0A8D1XAH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000056420   ⟸   ENSSSCT00000055375
RefSeq Acc Id: ENSSSCP00000079044   ⟸   ENSSSCT00000092098
RefSeq Acc Id: ENSSSCP00000081101   ⟸   ENSSSCT00000093143


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000017294 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005002633 UniProtKB/TrEMBL
  ENSSSCG00015003960 UniProtKB/TrEMBL
  ENSSSCG00025033780 UniProtKB/TrEMBL
  ENSSSCG00030006464 UniProtKB/TrEMBL
  ENSSSCG00035011462 UniProtKB/TrEMBL
  ENSSSCG00040043340 UniProtKB/TrEMBL
  ENSSSCG00050068642 UniProtKB/TrEMBL
  ENSSSCG00055014023 UniProtKB/TrEMBL
  ENSSSCG00060075938 UniProtKB/TrEMBL
  ENSSSCG00065004613 UniProtKB/TrEMBL
  ENSSSCG00070006228 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000055375 ENTREZGENE
  ENSSSCT00000055375.3 UniProtKB/TrEMBL
  ENSSSCT00000092098.1 UniProtKB/TrEMBL
  ENSSSCT00000093143.1 UniProtKB/TrEMBL
  ENSSSCT00005004010.1 UniProtKB/TrEMBL
  ENSSSCT00005004020.1 UniProtKB/TrEMBL
  ENSSSCT00005004028.1 UniProtKB/TrEMBL
  ENSSSCT00005004034.1 UniProtKB/TrEMBL
  ENSSSCT00005004040.1 UniProtKB/TrEMBL
  ENSSSCT00015005222.1 UniProtKB/TrEMBL
  ENSSSCT00015005237.1 UniProtKB/TrEMBL
  ENSSSCT00025046007.1 UniProtKB/TrEMBL
  ENSSSCT00030008689.1 UniProtKB/TrEMBL
  ENSSSCT00030008701.1 UniProtKB/TrEMBL
  ENSSSCT00035014414.1 UniProtKB/TrEMBL
  ENSSSCT00035014419.1 UniProtKB/TrEMBL
  ENSSSCT00040058041.1 UniProtKB/TrEMBL
  ENSSSCT00040058139.1 UniProtKB/TrEMBL
  ENSSSCT00050093684.1 UniProtKB/TrEMBL
  ENSSSCT00055027643.1 UniProtKB/TrEMBL
  ENSSSCT00060104088.1 UniProtKB/TrEMBL
  ENSSSCT00060104109.1 UniProtKB/TrEMBL
  ENSSSCT00060104154.1 UniProtKB/TrEMBL
  ENSSSCT00065006333.1 UniProtKB/TrEMBL
  ENSSSCT00065006335.1 UniProtKB/TrEMBL
  ENSSSCT00070011853.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro DCAF7-like UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report ssc:100514182 UniProtKB/TrEMBL
NCBI Gene DCAF7 ENTREZGENE
PANTHER DDB1- AND CUL4-ASSOCIATED FACTOR 7 UniProtKB/TrEMBL
  PTHR19919 UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A287BIR3 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1T4J1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0HPV2_PIG UniProtKB/TrEMBL
  A0A8D0I0H4_PIG UniProtKB/TrEMBL
  A0A8D0MEZ8_PIG UniProtKB/TrEMBL
  A0A8D1X9S7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1XAH7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FHX3_PIG UniProtKB/TrEMBL
  A0A8W4FRA5_PIG UniProtKB/TrEMBL
VGNC ID VGNC:87178 ENTREZGENE