PASK (PAS domain containing serine/threonine kinase) - Rat Genome Database

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Gene: PASK (PAS domain containing serine/threonine kinase) Sus scrofa
Analyze
Symbol: PASK
Name: PAS domain containing serine/threonine kinase
RGD ID: 13927129
Description: ENCODES a protein that exhibits ATP binding (inferred); phosphatidylinositol binding (inferred); protein kinase activity (inferred); INVOLVED IN energy homeostasis (inferred); intracellular signal transduction (inferred); negative regulation of glycogen biosynthetic process (inferred); ASSOCIATED WITH autistic disorder (ortholog); Bethlem Myopathy 1A (ortholog); chromosome 2q37 deletion syndrome (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: PAS domain-containing serine/threonine-protein kinase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15139,890,178 - 139,917,069 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115139,887,439 - 139,917,887 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215155,006,110 - 155,031,416 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA)
cytosol  (IBA,IEA)
nucleus  (IBA,IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PASK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15139,890,178 - 139,917,069 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115139,887,439 - 139,917,887 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215155,006,110 - 155,031,416 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PASK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382241,106,099 - 241,150,347 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2241,106,099 - 241,150,264 (-)EnsemblGRCh38hg38GRCh38
GRCh372242,045,514 - 242,089,637 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,694,188 - 241,737,551 (-)NCBINCBI36Build 36hg18NCBI36
Build 342241,765,504 - 241,808,868NCBI
Celera2235,715,217 - 235,758,602 (-)NCBICelera
Cytogenetic Map2q37.3NCBI
HuRef2233,801,521 - 233,845,836 (-)NCBIHuRef
CHM1_12242,051,569 - 242,095,450 (-)NCBICHM1_1
T2T-CHM13v2.02241,605,207 - 241,649,447 (-)NCBIT2T-CHM13v2.0
Pask
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39193,237,165 - 93,271,237 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl193,236,492 - 93,271,204 (-)EnsemblGRCm39 Ensembl
GRCm38193,309,437 - 93,343,522 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl193,308,770 - 93,343,482 (-)EnsemblGRCm38mm10GRCm38
MGSCv37195,206,014 - 95,239,365 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36195,139,843 - 95,167,980 (-)NCBIMGSCv36mm8
Celera196,254,103 - 96,287,403 (-)NCBICelera
Cytogenetic Map1DNCBI
cM Map147.24NCBI
Pask
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89101,291,673 - 101,333,288 (-)NCBIGRCr8
mRatBN7.2993,844,275 - 93,886,036 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl993,844,278 - 93,885,111 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9102,279,835 - 102,320,665 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09107,415,644 - 107,456,467 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09105,771,786 - 105,812,609 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.09100,450,595 - 100,479,719 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9100,450,586 - 100,479,868 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09100,106,950 - 100,136,074 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4992,582,177 - 92,623,004 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1992,786,946 - 92,827,773 (-)NCBI
Celera991,379,229 - 91,420,042 (-)NCBICelera
Cytogenetic Map9q36NCBI
Pask
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955542555,030 - 578,227 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955542539,806 - 578,496 (+)NCBIChiLan1.0ChiLan1.0
PASK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213143,795,782 - 143,850,798 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B143,810,747 - 143,865,694 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B128,364,745 - 128,418,837 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B247,162,011 - 247,215,451 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B247,162,011 - 247,214,803 (-)Ensemblpanpan1.1panPan2
PASK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12551,145,094 - 51,181,040 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2551,144,912 - 51,177,818 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2551,358,398 - 51,393,714 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02551,340,211 - 51,375,472 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2551,338,043 - 51,375,448 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12551,187,899 - 51,223,198 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02550,927,406 - 50,962,618 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02551,203,734 - 51,238,468 (-)NCBIUU_Cfam_GSD_1.0
Pask
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303192,515,388 - 192,555,345 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936745664,062 - 704,027 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PASK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110127,156,577 - 127,206,745 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10127,156,558 - 127,199,845 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604072,175,714 - 72,226,448 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pask
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248475,216,441 - 5,238,908 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248475,215,626 - 5,246,540 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PASK
664 total Variants

Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000017833   ⟹   ENSSSCP00000017352
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15139,887,531 - 139,917,089 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000017835   ⟹   ENSSSCP00000017354
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15139,881,221 - 139,887,258 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000044949   ⟹   ENSSSCP00000034965
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15139,890,178 - 139,917,069 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000049526   ⟹   ENSSSCP00000034008
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15139,887,361 - 139,917,089 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000067000   ⟹   ENSSSCP00000064485
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15139,883,441 - 139,917,089 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000082636   ⟹   ENSSSCP00000067093
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15139,883,441 - 139,917,089 (-)Ensembl
RefSeq Acc Id: XM_021075708   ⟹   XP_020931367
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115139,889,965 - 139,915,501 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021075709   ⟹   XP_020931368
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115139,887,439 - 139,915,501 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021075710   ⟹   XP_020931369
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115139,889,965 - 139,917,887 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021075711   ⟹   XP_020931370
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115139,889,965 - 139,917,034 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021075712   ⟹   XP_020931371
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115139,889,965 - 139,917,102 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021075713   ⟹   XP_020931372
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115139,893,974 - 139,915,501 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021075714   ⟹   XP_020931373
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115139,889,965 - 139,912,518 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020931368   ⟸   XM_021075709
- Peptide Label: isoform X2
- UniProtKB: A0A8D1MI67 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020931369   ⟸   XM_021075710
- Peptide Label: isoform X3
- UniProtKB: A0A8D1HIX2 (UniProtKB/TrEMBL),   A0A8D0TGA7 (UniProtKB/TrEMBL),   A0A8D1FSF8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020931371   ⟸   XM_021075712
- Peptide Label: isoform X3
- UniProtKB: A0A8D1HIX2 (UniProtKB/TrEMBL),   A0A8D0TGA7 (UniProtKB/TrEMBL),   A0A8D1FSF8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020931370   ⟸   XM_021075711
- Peptide Label: isoform X3
- UniProtKB: A0A8D1HIX2 (UniProtKB/TrEMBL),   A0A8D0TGA7 (UniProtKB/TrEMBL),   A0A8D1FSF8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020931367   ⟸   XM_021075708
- Peptide Label: isoform X1
- UniProtKB: A0A8D0TGA7 (UniProtKB/TrEMBL),   A0A8D1FSF8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020931373   ⟸   XM_021075714
- Peptide Label: isoform X5
- UniProtKB: A0A8D1FSF8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020931372   ⟸   XM_021075713
- Peptide Label: isoform X4
- UniProtKB: A0A480RZ83 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000034965   ⟸   ENSSSCT00000044949
RefSeq Acc Id: ENSSSCP00000034008   ⟸   ENSSSCT00000049526
RefSeq Acc Id: ENSSSCP00000017352   ⟸   ENSSSCT00000017833
RefSeq Acc Id: ENSSSCP00000017354   ⟸   ENSSSCT00000017835
RefSeq Acc Id: ENSSSCP00000064485   ⟸   ENSSSCT00000067000
RefSeq Acc Id: ENSSSCP00000067093   ⟸   ENSSSCT00000082636
Protein Domains
PAS   Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016378 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025075378 UniProtKB/TrEMBL
  ENSSSCG00030019621 UniProtKB/TrEMBL
  ENSSSCG00035072201 UniProtKB/TrEMBL
  ENSSSCG00040065569 UniProtKB/TrEMBL
  ENSSSCG00045014459 UniProtKB/TrEMBL
  ENSSSCG00050040391 UniProtKB/TrEMBL
  ENSSSCG00065075062 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000044949 ENTREZGENE
  ENSSSCT00000044949.3 UniProtKB/TrEMBL
  ENSSSCT00025104127.1 UniProtKB/TrEMBL
  ENSSSCT00030027086.1 UniProtKB/TrEMBL
  ENSSSCT00035097689.1 UniProtKB/TrEMBL
  ENSSSCT00040089508.1 UniProtKB/TrEMBL
  ENSSSCT00040089721.1 UniProtKB/TrEMBL
  ENSSSCT00040089935.1 UniProtKB/TrEMBL
  ENSSSCT00045024671.1 UniProtKB/TrEMBL
  ENSSSCT00050054614.1 UniProtKB/TrEMBL
  ENSSSCT00050054639.1 UniProtKB/TrEMBL
  ENSSSCT00065103486.1 UniProtKB/TrEMBL
Gene3D-CATH PAS domain UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/TrEMBL
  PAS_fold UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene PASK ENTREZGENE
PANTHER MAP/MICROTUBULE AFFINITY-REGULATING KINASE UniProtKB/TrEMBL
  PAS DOMAIN-CONTAINING SERINE/THREONINE-PROTEIN KINASE UniProtKB/TrEMBL
Pfam PAS UniProtKB/TrEMBL
  PAS_9 UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PROSITE PAS UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART PAS UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF55785 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A286ZU04_PIG UniProtKB/TrEMBL
  A0A480RZ83 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0TGA7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1AYC7_PIG UniProtKB/TrEMBL
  A0A8D1FPF7_PIG UniProtKB/TrEMBL
  A0A8D1FS07_PIG UniProtKB/TrEMBL
  A0A8D1FSF8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1HIX2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1MI67 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:95840 ENTREZGENE