LAMA1 (laminin subunit alpha 1) - Rat Genome Database

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Gene: LAMA1 (laminin subunit alpha 1) Sus scrofa
Analyze
Symbol: LAMA1
Name: laminin subunit alpha 1
RGD ID: 13921673
Description: ENCODES a protein that exhibits extracellular matrix structural constituent (inferred); glycosphingolipid binding (inferred); signaling receptor binding (inferred); INVOLVED IN branching involved in salivary gland morphogenesis (ortholog); cell surface receptor signaling pathway (ortholog); epithelial tube branching involved in lung morphogenesis (ortholog); PARTICIPATES IN glypican signaling pathway; syndecan signaling pathway; ASSOCIATED WITH chromosome 18p deletion syndrome (ortholog); Colorectal Neoplasms (ortholog); genetic disease (ortholog); FOUND IN basement membrane (inferred); cell-cell junction (inferred); extracellular matrix (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: laminin subunit alpha-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6100,332,956 - 100,468,454 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16100,332,843 - 100,468,457 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LAMA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6100,332,956 - 100,468,454 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16100,332,843 - 100,468,457 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LAMA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38186,941,742 - 7,117,797 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl186,941,742 - 7,117,797 (-)EnsemblGRCh38hg38GRCh38
GRCh37186,941,741 - 7,117,796 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36186,931,885 - 7,107,813 (-)NCBINCBI36Build 36hg18NCBI36
Build 34186,931,887 - 7,107,813NCBI
Celera186,802,111 - 7,003,045 (-)NCBICelera
Cytogenetic Map18p11.31NCBI
HuRef186,905,118 - 7,080,842 (-)NCBIHuRef
CHM1_1186,941,780 - 7,117,762 (-)NCBICHM1_1
T2T-CHM13v2.0187,102,299 - 7,278,323 (-)NCBIT2T-CHM13v2.0
Lama1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391768,004,129 - 68,129,640 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1768,004,254 - 68,129,642 (+)EnsemblGRCm39 Ensembl
GRCm381767,697,127 - 67,822,645 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1767,697,259 - 67,822,647 (+)EnsemblGRCm38mm10GRCm38
MGSCv371768,046,605 - 68,171,985 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361767,602,232 - 67,727,594 (+)NCBIMGSCv36mm8
Celera1771,993,823 - 72,120,045 (+)NCBICelera
Cytogenetic Map17E1.1NCBI
cM Map1738.8NCBI
Lama1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89115,139,548 - 115,263,620 (+)NCBIGRCr8
mRatBN7.29107,692,770 - 107,816,847 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9107,692,770 - 107,817,478 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9116,084,681 - 116,208,750 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09121,206,911 - 121,330,979 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09119,550,575 - 119,674,645 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.09115,916,907 - 116,042,123 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9115,916,907 - 116,042,123 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09115,406,905 - 115,531,632 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49106,855,708 - 106,980,651 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.19107,065,234 - 107,189,814 (+)NCBI
Celera9104,852,718 - 104,977,464 (+)NCBICelera
Cytogenetic Map9q38NCBI
Lama1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554024,285,492 - 4,400,348 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554024,281,415 - 4,397,158 (+)NCBIChiLan1.0ChiLan1.0
LAMA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21731,326,443 - 31,501,876 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11817,019,078 - 17,194,469 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0187,159,568 - 7,335,363 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1189,482,878 - 9,656,942 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl189,482,895 - 9,656,800 (+)Ensemblpanpan1.1panPan2
LAMA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1773,309,383 - 73,438,543 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl773,309,388 - 73,448,151 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha772,704,162 - 72,859,440 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0773,362,093 - 73,517,591 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl773,362,098 - 73,517,567 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1773,065,788 - 73,221,046 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0773,094,647 - 73,250,187 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0773,389,565 - 73,544,837 (-)NCBIUU_Cfam_GSD_1.0
Lama1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494469,843,440 - 69,995,263 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936670359,582 - 484,539 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936670359,343 - 511,126 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LAMA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11865,996,233 - 66,162,510 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605040,913,097 - 41,078,945 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lama1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477016,359,255 - 16,462,817 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477016,358,952 - 16,490,986 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LAMA1
3631 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 3 2 23 2 2 1
Below cutoff 3 4 3 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021096069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000050627   ⟹   ENSSSCP00000042818
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl6100,332,956 - 100,468,454 (+)Ensembl
RefSeq Acc Id: XM_021096069   ⟹   XP_020951728
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.16100,332,843 - 100,468,457 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020951728 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000042818
  ENSSSCP00000042818.3
  ENSSSCP00015018372.1
  ENSSSCP00035037036.1
  ENSSSCP00045038766.1
  ENSSSCP00055024714.1
  ENSSSCP00055024943.1
  ENSSSCP00070044430.1
Reference Protein Sequences
RefSeq Acc Id: XP_020951728   ⟸   XM_021096069
- UniProtKB: A0A4X1VLN1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000042818   ⟸   ENSSSCT00000050627
Protein Domains
Laminin EGF-like   Laminin G   Laminin IV type A   Laminin N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000034767 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015034815 UniProtKB/TrEMBL
  ENSSSCG00035065777 UniProtKB/TrEMBL
  ENSSSCG00045032536 UniProtKB/TrEMBL
  ENSSSCG00055015764 UniProtKB/TrEMBL
  ENSSSCG00070026199 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000050627 ENTREZGENE
  ENSSSCT00000050627.3 UniProtKB/TrEMBL
  ENSSSCT00015046428.1 UniProtKB/TrEMBL
  ENSSSCT00035088620.1 UniProtKB/TrEMBL
  ENSSSCT00045055581.1 UniProtKB/TrEMBL
  ENSSSCT00055031044.1 UniProtKB/TrEMBL
  ENSSSCT00055031328.1 UniProtKB/TrEMBL
  ENSSSCT00070052489.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
  Tie2 ligand-binding domain superfamily UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  Galactose-bd-like_sf UniProtKB/TrEMBL
  Laminin_aI UniProtKB/TrEMBL
  Laminin_dom_II UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_G UniProtKB/TrEMBL
  Laminin_IV UniProtKB/TrEMBL
  Laminin_N UniProtKB/TrEMBL
NCBI Gene LAMA1 ENTREZGENE
PANTHER LAMININ SUBUNIT ALPHA-1 UniProtKB/TrEMBL
  LAMININ SUBUNIT GAMMA-1 UniProtKB/TrEMBL
  NETRIN/LAMININ-RELATED UniProtKB/TrEMBL
  PIKACHURIN-LIKE PROTEIN UniProtKB/TrEMBL
Pfam Laminin_B UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_G_1 UniProtKB/TrEMBL
  Laminin_I UniProtKB/TrEMBL
  Laminin_II UniProtKB/TrEMBL
  Laminin_N UniProtKB/TrEMBL
PRINTS EGFLAMININ UniProtKB/TrEMBL
PROSITE EGF_LAM_1 UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/TrEMBL
  LAM_G_DOMAIN UniProtKB/TrEMBL
  LAMININ_IVA UniProtKB/TrEMBL
  LAMININ_NTER UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_Lam UniProtKB/TrEMBL
  LamB UniProtKB/TrEMBL
  LamG UniProtKB/TrEMBL
  LamNT UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  Methyl-accepting chemotaxis protein (MCP) signaling domain UniProtKB/TrEMBL
  SSF49785 UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
UniProt A0A287AG36_PIG UniProtKB/TrEMBL
  A0A4X1VLN1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0NM36_PIG UniProtKB/TrEMBL
  A0A8D1ANC0_PIG UniProtKB/TrEMBL
  A0A8D1IXC4_PIG UniProtKB/TrEMBL
  A0A8D1QRG4_PIG UniProtKB/TrEMBL
  A0A8D1QTS2_PIG UniProtKB/TrEMBL
VGNC ID VGNC:89619 ENTREZGENE