ZHX3 (zinc fingers and homeoboxes 3) - Rat Genome Database

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Gene: ZHX3 (zinc fingers and homeoboxes 3) Sus scrofa
Analyze
Symbol: ZHX3
Name: zinc fingers and homeoboxes 3
RGD ID: 13918047
Description: ENCODES a protein that exhibits RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH coronary artery disease (ortholog); focal epilepsy (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: zinc fingers and homeoboxes protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1743,848,352 - 43,962,992 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11743,848,345 - 43,963,084 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21749,248,058 - 49,252,810 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA)
nucleus  (IBA,IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ZHX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1743,848,352 - 43,962,992 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11743,848,345 - 43,963,084 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21749,248,058 - 49,252,810 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZHX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382041,178,455 - 41,317,731 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2041,178,448 - 41,317,731 (-)EnsemblGRCh38hg38GRCh38
GRCh372039,807,095 - 39,946,371 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362039,240,503 - 39,362,153 (-)NCBINCBI36Build 36hg18NCBI36
Build 342039,240,502 - 39,362,153NCBI
Celera2036,517,656 - 36,639,406 (-)NCBICelera
Cytogenetic Map20q12NCBI
HuRef2036,545,141 - 36,666,992 (-)NCBIHuRef
CHM1_12039,711,487 - 39,833,056 (-)NCBICHM1_1
T2T-CHM13v2.02042,910,141 - 43,049,531 (-)NCBIT2T-CHM13v2.0
Zhx3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392160,612,367 - 160,714,910 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2160,590,628 - 160,714,918 (-)EnsemblGRCm39 Ensembl
GRCm382160,770,447 - 160,872,990 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2160,748,708 - 160,872,998 (-)EnsemblGRCm38mm10GRCm38
MGSCv372160,596,183 - 160,698,726 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362160,461,888 - 160,564,431 (-)NCBIMGSCv36mm8
Celera2166,702,506 - 166,803,659 (-)NCBICelera
Cytogenetic Map2H2NCBI
cM Map280.97NCBI
Zhx3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83169,837,497 - 169,968,371 (-)NCBIGRCr8
mRatBN7.23149,417,787 - 149,548,671 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3149,417,818 - 149,527,079 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3153,230,920 - 153,328,717 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03161,730,305 - 161,828,105 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03159,469,934 - 159,567,975 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03156,759,820 - 156,868,173 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3156,764,751 - 156,777,999 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03162,989,355 - 163,095,228 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43151,560,440 - 151,574,257 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13151,478,388 - 151,479,956 (-)NCBI
Celera3148,096,662 - 148,110,463 (-)NCBICelera
Cytogenetic Map3q42NCBI
Zhx3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544515,632,995 - 15,785,238 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544515,632,723 - 15,785,238 (+)NCBIChiLan1.0ChiLan1.0
ZHX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22146,920,289 - 47,059,855 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12046,913,383 - 47,052,950 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02037,518,569 - 37,659,417 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12038,617,878 - 38,738,631 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2038,621,651 - 38,755,797 (-)Ensemblpanpan1.1panPan2
ZHX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12429,217,434 - 29,343,475 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2429,223,236 - 29,282,171 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2428,862,936 - 28,988,759 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02429,923,064 - 30,048,336 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2429,923,070 - 30,048,272 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12429,191,952 - 29,317,181 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02429,295,800 - 29,420,657 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02429,792,021 - 29,917,169 (-)NCBIUU_Cfam_GSD_1.0
Zhx3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640178,152,880 - 178,285,053 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936561506,142 - 590,595 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936561464,443 - 596,604 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZHX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1222,455,121 - 22,508,182 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl222,456,123 - 22,590,134 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
ChlSab1.1 Ensembl222,456,123 - 22,590,134 (+)NCBIChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605071,273,983 - 71,414,095 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zhx3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249191,808,819 - 1,971,778 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249191,802,708 - 1,972,676 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ZHX3
2616 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 9 4 3 5 2 23 2 3 3
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000040153   ⟹   ENSSSCP00000044175
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1743,851,295 - 43,962,992 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000057467   ⟹   ENSSSCP00000047888
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1743,848,352 - 43,858,921 (-)Ensembl
RefSeq Acc Id: NM_001258405   ⟹   NP_001245334
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11743,854,173 - 43,858,921 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021077228   ⟹   XP_020932887
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11743,848,345 - 43,962,631 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021077229   ⟹   XP_020932888
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11743,848,349 - 43,963,084 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021077230   ⟹   XP_020932889
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11743,848,346 - 43,900,255 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021077231   ⟹   XP_020932890
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11743,848,349 - 43,963,084 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021077232   ⟹   XP_020932891
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11743,848,346 - 43,962,629 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021077233   ⟹   XP_020932892
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11743,848,346 - 43,962,631 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020932887   ⟸   XM_021077228
- Peptide Label: isoform X1
- UniProtKB: A0A287BCP2 (UniProtKB/TrEMBL),   A0A8D1RPA7 (UniProtKB/TrEMBL),   A0A287AVE4 (UniProtKB/TrEMBL),   A0A8D1KV27 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020932892   ⟸   XM_021077233
- Peptide Label: isoform X2
- UniProtKB: A0A287AVE4 (UniProtKB/TrEMBL),   A0A8D1KV27 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020932891   ⟸   XM_021077232
- Peptide Label: isoform X1
- UniProtKB: A0A287BCP2 (UniProtKB/TrEMBL),   A0A8D1RPA7 (UniProtKB/TrEMBL),   A0A287AVE4 (UniProtKB/TrEMBL),   A0A8D1KV27 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020932889   ⟸   XM_021077230
- Peptide Label: isoform X1
- UniProtKB: A0A287BCP2 (UniProtKB/TrEMBL),   A0A8D1RPA7 (UniProtKB/TrEMBL),   A0A287AVE4 (UniProtKB/TrEMBL),   A0A8D1KV27 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020932890   ⟸   XM_021077231
- Peptide Label: isoform X1
- UniProtKB: A0A287BCP2 (UniProtKB/TrEMBL),   A0A8D1RPA7 (UniProtKB/TrEMBL),   A0A287AVE4 (UniProtKB/TrEMBL),   A0A8D1KV27 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020932888   ⟸   XM_021077229
- Peptide Label: isoform X1
- UniProtKB: A0A287BCP2 (UniProtKB/TrEMBL),   A0A8D1RPA7 (UniProtKB/TrEMBL),   A0A287AVE4 (UniProtKB/TrEMBL),   A0A8D1KV27 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001245334   ⟸   NM_001258405
- UniProtKB: A0A287BCP2 (UniProtKB/TrEMBL),   A0A8D1RPA7 (UniProtKB/TrEMBL),   A0A287AVE4 (UniProtKB/TrEMBL),   A0A8D1KV27 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000044175   ⟸   ENSSSCT00000040153
RefSeq Acc Id: ENSSSCP00000047888   ⟸   ENSSSCT00000057467
Protein Domains
Homeobox


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000032566 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025035013 UniProtKB/TrEMBL
  ENSSSCG00035064039 UniProtKB/TrEMBL
  ENSSSCG00045011808 UniProtKB/TrEMBL
  ENSSSCG00055024240 UniProtKB/TrEMBL
  ENSSSCG00065023127 UniProtKB/TrEMBL
  ENSSSCG00070011119 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000040153 ENTREZGENE
  ENSSSCT00000040153.2 UniProtKB/TrEMBL
  ENSSSCT00000057467.3 UniProtKB/TrEMBL
  ENSSSCT00025047792.1 UniProtKB/TrEMBL
  ENSSSCT00035086148.1 UniProtKB/TrEMBL
  ENSSSCT00035086154.1 UniProtKB/TrEMBL
  ENSSSCT00045020080.1 UniProtKB/TrEMBL
  ENSSSCT00055047782.1 UniProtKB/TrEMBL
  ENSSSCT00055047830.1 UniProtKB/TrEMBL
  ENSSSCT00065030777.1 UniProtKB/TrEMBL
  ENSSSCT00065030783.1 UniProtKB/TrEMBL
  ENSSSCT00070021599.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Homez_homeobox_dom UniProtKB/TrEMBL
  ZHX_Znf_C2H2 UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
KEGG Report ssc:100156548 UniProtKB/TrEMBL
NCBI Gene ZHX3 ENTREZGENE
PANTHER ZINC FINGERS AND HOMEOBOXES PROTEIN 3 UniProtKB/TrEMBL
  ZINC-FINGERS AND HOMEOBOXES RELATED UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
  Homez UniProtKB/TrEMBL
  zf_C2H2_ZHX UniProtKB/TrEMBL
PROSITE HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A287AVE4 ENTREZGENE, UniProtKB/TrEMBL
  A0A287BCP2 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TRN0_PIG UniProtKB/TrEMBL
  A0A8D1KV27 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1RPA7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:95717 ENTREZGENE