NAGLU (N-acetyl-alpha-glucosaminidase) - Rat Genome Database

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Gene: NAGLU (N-acetyl-alpha-glucosaminidase) Sus scrofa
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Symbol: NAGLU
Name: N-acetyl-alpha-glucosaminidase
RGD ID: 13906938
Description: ENCODES a protein that exhibits alpha-N-acetylglucosaminidase activity (inferred); hydrolase activity (inferred); INVOLVED IN adult behavior (inferred); amyloid precursor protein metabolic process (inferred); aorta development (inferred); FOUND IN extracellular exosome (inferred); lysosomal lumen (inferred); lysosome (inferred)
Type: protein-coding
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
NCBI Annotation Information: Genome Annotation Status: not in current annotation release
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,271,351 - 20,279,777 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21220,485,024 - 20,492,536 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adult behavior  (IEA)
amyloid precursor protein metabolic process  (IEA)
aorta development  (IEA)
aorta morphogenesis  (IEA)
astrocyte activation  (IEA)
astrocyte differentiation  (IEA)
autophagy  (IEA)
cardiac muscle cell development  (IEA)
cell surface receptor signaling pathway via STAT  (IEA)
cellular lipid catabolic process  (IEA)
cellular response to organic cyclic compound  (IEA)
cellular response to oxidative stress  (IEA)
cerebellar Purkinje cell layer development  (IEA)
collagen metabolic process  (IEA)
cone retinal bipolar cell differentiation  (IEA)
cytoplasm organization  (IEA)
determination of adult lifespan  (IEA)
endothelium development  (IEA)
exploration behavior  (IEA)
ganglioside metabolic process  (IEA)
gene expression  (IEA)
glycoprotein metabolic process  (IEA)
glycosaminoglycan metabolic process  (IEA)
Golgi organization  (IEA)
hair follicle morphogenesis  (IEA)
heart development  (IEA)
heart valve development  (IEA)
heparan sulfate proteoglycan catabolic process  (IEA)
heparan sulfate proteoglycan metabolic process  (IEA)
heparin metabolic process  (IEA)
hormone metabolic process  (IEA)
inflammatory response  (IEA)
inner ear receptor cell development  (IEA)
left ventricular cardiac muscle tissue morphogenesis  (IEA)
limb development  (IEA)
liver development  (IEA)
locomotor rhythm  (IEA)
locomotory behavior  (IEA)
lysosome organization  (IEA)
maintenance of blood-brain barrier  (IEA)
microglia differentiation  (IEA)
microglial cell activation  (IEA)
middle ear morphogenesis  (IEA)
mitral valve morphogenesis  (IEA)
motor behavior  (IEA)
multicellular organismal-level iron ion homeostasis  (IEA)
nerve development  (IEA)
neurogenesis  (IEA)
neuroinflammatory response  (IEA)
obsolete cellular response to organic substance  (IEA)
proteasome-mediated ubiquitin-dependent protein catabolic process  (IEA)
protein processing  (IEA)
proteoglycan metabolic process  (IEA)
response to disaccharide  (IEA)
response to lipopolysaccharide  (IEA)
response to wounding  (IEA)
retina development in camera-type eye  (IEA)
retinal rod cell development  (IEA)
rod bipolar cell differentiation  (IEA)
sequestering of iron ion  (IEA)
superoxide metabolic process  (IEA)
toll-like receptor 4 signaling pathway  (IEA)
vacuole organization  (IEA)
vasculature development  (IEA)
vesicle tethering  (IEA)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000067086   ⟹   ENSSSCP00000063969
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1220,271,351 - 20,279,777 (-)Ensembl
Protein Sequences
Ensembl Protein ENSSSCP00000063969.1
Reference Protein Sequences
RefSeq Acc Id: ENSSSCP00000063969   ⟸   ENSSSCT00000067086
Protein Domains
Alpha-N-acetylglucosaminidase C-terminal   Alpha-N-acetylglucosaminidase N-terminal   Alpha-N-acetylglucosaminidase tim-barrel


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000046466 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000067086.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.379.10 UniProtKB/TrEMBL
  Glycosidases UniProtKB/TrEMBL
  N-acetyl-b-d-glucoasminidase UniProtKB/TrEMBL
InterPro Glycoside_hydrolase_SF UniProtKB/TrEMBL
  Hex-like_dom2 UniProtKB/TrEMBL
  NAGLU UniProtKB/TrEMBL
  NAGLU_C UniProtKB/TrEMBL
  NAGLU_N UniProtKB/TrEMBL
  NAGLU_tim-barrel UniProtKB/TrEMBL
NCBI Gene NAGLU ENTREZGENE
PANTHER ALPHA-N-ACETYLGLUCOSAMINIDASE UniProtKB/TrEMBL
  PTHR12872 UniProtKB/TrEMBL
Pfam NAGLU UniProtKB/TrEMBL
  NAGLU_C UniProtKB/TrEMBL
  NAGLU_N UniProtKB/TrEMBL
Superfamily-SCOP SSF51445 UniProtKB/TrEMBL
UniProt A0A5G2QHV1_PIG UniProtKB/TrEMBL