RNF125 (ring finger protein 125) - Rat Genome Database

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Gene: RNF125 (ring finger protein 125) Sus scrofa
Analyze
Symbol: RNF125
Name: ring finger protein 125
RGD ID: 13894823
Description: ENCODES a protein that exhibits ubiquitin-protein transferase activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); Tenorio Syndrome (ortholog); FOUND IN Golgi membrane (inferred); intracellular membrane-bounded organelle (inferred); VCP-NPL4-UFD1 AAA ATPase complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase RNF125
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6115,857,721 - 115,903,677 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16115,857,697 - 115,905,550 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26108,515,308 - 108,583,425 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
RNF125
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6115,857,721 - 115,903,677 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16115,857,697 - 115,905,550 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26108,515,308 - 108,583,425 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNF125
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381832,018,825 - 32,088,144 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1832,018,825 - 32,073,219 (+)EnsemblGRCh38hg38GRCh38
GRCh371829,598,788 - 29,653,182 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361827,852,443 - 27,907,152 (+)NCBINCBI36Build 36hg18NCBI36
Build 341827,852,442 - 27,903,161NCBI
Celera1826,404,874 - 26,460,130 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
HuRef1826,455,131 - 26,510,081 (+)NCBIHuRef
CHM1_11829,525,999 - 29,580,720 (+)NCBICHM1_1
T2T-CHM13v2.01832,209,216 - 32,280,737 (+)NCBIT2T-CHM13v2.0
Rnf125
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391821,077,672 - 21,120,416 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1821,077,682 - 21,116,919 (+)EnsemblGRCm39 Ensembl
GRCm381820,944,615 - 20,987,359 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1820,944,625 - 20,983,862 (+)EnsemblGRCm38mm10GRCm38
MGSCv371821,103,126 - 21,142,349 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361821,087,635 - 21,126,858 (+)NCBIMGSCv36mm8
Celera1821,440,322 - 21,479,523 (+)NCBICelera
Cytogenetic Map18A2NCBI
Rnf125
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81812,528,995 - 12,550,646 (+)NCBIGRCr8
mRatBN7.21812,254,066 - 12,275,719 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1812,253,852 - 12,275,983 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1812,444,325 - 12,465,962 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01813,231,979 - 13,253,612 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01812,503,627 - 12,525,258 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01815,193,226 - 15,225,454 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1815,192,962 - 15,225,427 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01814,972,530 - 15,004,384 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41812,726,187 - 12,747,639 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11812,738,496 - 12,774,725 (+)NCBI
Celera1812,252,978 - 12,274,631 (+)NCBICelera
Cytogenetic Map18p12NCBI
Rnf125
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540219,295,809 - 19,309,987 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540219,276,157 - 19,310,605 (+)NCBIChiLan1.0ChiLan1.0
RNF125
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21749,395,711 - 49,450,141 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11835,088,307 - 35,159,003 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01825,227,353 - 25,297,186 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11828,823,807 - 28,873,667 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1828,824,183 - 28,873,068 (+)Ensemblpanpan1.1panPan2
RNF125
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1757,570,779 - 57,607,485 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl757,574,738 - 57,608,017 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha757,004,743 - 57,041,487 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0757,552,615 - 57,589,372 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl757,552,619 - 57,589,286 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1757,229,577 - 57,266,076 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0757,248,867 - 57,285,615 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0757,544,766 - 57,581,517 (-)NCBIUU_Cfam_GSD_1.0
Rnf125
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494453,226,460 - 53,267,389 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366821,231,823 - 1,268,657 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366821,228,903 - 1,268,651 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF125
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11848,665,694 - 48,712,371 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1848,666,554 - 48,711,604 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605023,218,377 - 23,265,573 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf125
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624770909,808 - 942,386 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RNF125
900 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 5 1
Low 10 2 3 2 23 2 3 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000004129   ⟹   ENSSSCP00000004036
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl6115,857,881 - 115,898,504 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000035939   ⟹   ENSSSCP00000028585
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl6115,857,721 - 115,903,675 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000072361   ⟹   ENSSSCP00000069247
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl6115,858,359 - 115,903,677 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000080973   ⟹   ENSSSCP00000062653
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl6115,857,739 - 115,903,676 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000083559   ⟹   ENSSSCP00000073490
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl6115,857,084 - 115,903,678 (+)Ensembl
RefSeq Acc Id: XM_003127888   ⟹   XP_003127936
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.16115,857,697 - 115,904,579 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005665329   ⟹   XP_005665386
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.16115,857,698 - 115,898,735 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013999274   ⟹   XP_013854728
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.16115,857,698 - 115,905,550 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021096213   ⟹   XP_020951872
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.16115,857,698 - 115,899,008 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021096214   ⟹   XP_020951873
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.16115,858,294 - 115,904,579 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003127936   ⟸   XM_003127888
- Peptide Label: isoform X1
- UniProtKB: A0A4X1VMZ1 (UniProtKB/TrEMBL),   F1SAL7 (UniProtKB/TrEMBL),   A0A8D0W5K1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013854728   ⟸   XM_013999274
- Peptide Label: isoform X3
- UniProtKB: A0A8D1AQE6 (UniProtKB/TrEMBL),   K7GL56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020951872   ⟸   XM_021096213
- Peptide Label: isoform X2
- UniProtKB: A0A5G2QEN7 (UniProtKB/TrEMBL),   A0A8D1L1F5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005665386   ⟸   XM_005665329
- Peptide Label: isoform X4
- UniProtKB: A0A8D1AQE6 (UniProtKB/TrEMBL),   K7GL56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020951873   ⟸   XM_021096214
- Peptide Label: isoform X5
- UniProtKB: A0A5G2REF6 (UniProtKB/TrEMBL),   A0A8D0W7H2 (UniProtKB/TrEMBL),   A0A8D1Z530 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000073490   ⟸   ENSSSCT00000083559
RefSeq Acc Id: ENSSSCP00000062653   ⟸   ENSSSCT00000080973
RefSeq Acc Id: ENSSSCP00000028585   ⟸   ENSSSCT00000035939
RefSeq Acc Id: ENSSSCP00000004036   ⟸   ENSSSCT00000004129
RefSeq Acc Id: ENSSSCP00000069247   ⟸   ENSSSCT00000072361
Protein Domains
C2HC RNF-type   RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000003729 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005021292 UniProtKB/TrEMBL
  ENSSSCG00015034184 UniProtKB/TrEMBL
  ENSSSCG00025041886 UniProtKB/TrEMBL
  ENSSSCG00030025451 UniProtKB/TrEMBL
  ENSSSCG00035067212 UniProtKB/TrEMBL
  ENSSSCG00040064753 UniProtKB/TrEMBL
  ENSSSCG00045024516 UniProtKB/TrEMBL
  ENSSSCG00050071069 UniProtKB/TrEMBL
  ENSSSCG00055002581 UniProtKB/TrEMBL
  ENSSSCG00060060054 UniProtKB/TrEMBL
  ENSSSCG00065045650 UniProtKB/TrEMBL
  ENSSSCG00070025075 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000004129 ENTREZGENE
  ENSSSCT00000004129.5 UniProtKB/TrEMBL
  ENSSSCT00000035939 ENTREZGENE
  ENSSSCT00000035939.4 UniProtKB/TrEMBL
  ENSSSCT00000072361 ENTREZGENE
  ENSSSCT00000072361.2 UniProtKB/TrEMBL
  ENSSSCT00000080973 ENTREZGENE
  ENSSSCT00000080973.2 UniProtKB/TrEMBL
  ENSSSCT00005033584.1 UniProtKB/TrEMBL
  ENSSSCT00005033599.1 UniProtKB/TrEMBL
  ENSSSCT00015045295.1 UniProtKB/TrEMBL
  ENSSSCT00015045335.1 UniProtKB/TrEMBL
  ENSSSCT00015045574.1 UniProtKB/TrEMBL
  ENSSSCT00025056732.1 UniProtKB/TrEMBL
  ENSSSCT00025056824.1 UniProtKB/TrEMBL
  ENSSSCT00025057048.1 UniProtKB/TrEMBL
  ENSSSCT00030035537.1 UniProtKB/TrEMBL
  ENSSSCT00030035549.1 UniProtKB/TrEMBL
  ENSSSCT00030035557.1 UniProtKB/TrEMBL
  ENSSSCT00030035567.1 UniProtKB/TrEMBL
  ENSSSCT00035090626.1 UniProtKB/TrEMBL
  ENSSSCT00035090632.1 UniProtKB/TrEMBL
  ENSSSCT00035090651.1 UniProtKB/TrEMBL
  ENSSSCT00040088414.1 UniProtKB/TrEMBL
  ENSSSCT00040088506.1 UniProtKB/TrEMBL
  ENSSSCT00040088600.1 UniProtKB/TrEMBL
  ENSSSCT00040088672.1 UniProtKB/TrEMBL
  ENSSSCT00045041741.1 UniProtKB/TrEMBL
  ENSSSCT00045041808.1 UniProtKB/TrEMBL
  ENSSSCT00045041964.1 UniProtKB/TrEMBL
  ENSSSCT00050096923.1 UniProtKB/TrEMBL
  ENSSSCT00050096931.1 UniProtKB/TrEMBL
  ENSSSCT00055004926.1 UniProtKB/TrEMBL
  ENSSSCT00055004935.1 UniProtKB/TrEMBL
  ENSSSCT00055004952.1 UniProtKB/TrEMBL
  ENSSSCT00060081939.1 UniProtKB/TrEMBL
  ENSSSCT00060081947.1 UniProtKB/TrEMBL
  ENSSSCT00060081958.1 UniProtKB/TrEMBL
  ENSSSCT00060081966.1 UniProtKB/TrEMBL
  ENSSSCT00065062467.1 UniProtKB/TrEMBL
  ENSSSCT00065062471.1 UniProtKB/TrEMBL
  ENSSSCT00065062476.1 UniProtKB/TrEMBL
  ENSSSCT00065062478.1 UniProtKB/TrEMBL
  ENSSSCT00070050121.1 UniProtKB/TrEMBL
  ENSSSCT00070050122.1 UniProtKB/TrEMBL
  ENSSSCT00070050124.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro Di19_Zn_binding_dom UniProtKB/TrEMBL
  ZF_C2HC_RNF UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report ssc:100517591 UniProtKB/TrEMBL
NCBI Gene RNF125 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE RNF125 UniProtKB/TrEMBL
  ZINC FINGER, RING/FYVE/PHD-TYPE UniProtKB/TrEMBL
Pfam zf-C3HC4_2 UniProtKB/TrEMBL
  zf-Di19 UniProtKB/TrEMBL
  zf_C2HC_14 UniProtKB/TrEMBL
PROSITE ZF_C2HC_RNF UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A4X1VG49_PIG UniProtKB/TrEMBL
  A0A4X1VK73_PIG UniProtKB/TrEMBL
  A0A4X1VMZ1 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QEN7 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2REF6 ENTREZGENE
  A0A8D0W5K1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0W7H2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1AQE6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1L1F5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1Z530 ENTREZGENE, UniProtKB/TrEMBL
  F1SAL7 ENTREZGENE, UniProtKB/TrEMBL
  K7GL56 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A5G2REF6 UniProtKB/TrEMBL
VGNC ID VGNC:92352 ENTREZGENE