UOX (urate oxidase) - Rat Genome Database

Name: UOX
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: UOX (urate oxidase) Sus scrofa

Analyze

Symbol:

UOX

Name:

urate oxidase

RGD ID:

13876724

Description:

ENCODES a protein that exhibits oxidoreductase activity (inferred); urate oxidase activity (inferred); INVOLVED IN adenosine catabolic process (inferred); allantoin metabolic process (inferred); amide catabolic process (inferred); FOUND IN peroxisome (inferred)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

uricase

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	129,343,592 - 129,375,724 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	129,343,632 - 129,374,833 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenosine catabolic process (IEA)

allantoin metabolic process (IEA)

amide catabolic process (IEA)

AMP catabolic process (IEA)

dAMP catabolic process (IEA)

deoxyadenosine catabolic process (IEA)

deoxyguanosine catabolic process (IEA)

deoxyinosine catabolic process (IEA)

dGMP catabolic process (IEA)

GMP catabolic process (IEA)

guanine catabolic process (IEA)

hypoxanthine catabolic process (IEA)

IMP catabolic process (IEA)

inosine catabolic process (IEA)

purine nucleobase catabolic process (IBA,IEA)

purine nucleobase metabolic process (IEA)

urate catabolic process (IBA,IEA)

xanthine catabolic process (IEA)

Cellular Component

peroxisome (IBA,IEA)

Molecular Function

oxidoreductase activity (IEA)

urate oxidase activity (IBA,IEA)

References

Additional References at PubMed

PMID:2594778	PMID:3344434	PMID:8785609	PMID:14681463	PMID:17145712	PMID:22301074	PMID:30032202

Genomics

Variants

Variants in UOX
319 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	nervous system	renal system	reproductive system	respiratory system
High
Medium
Low			3	2	13	2	2
Below cutoff	4	2		3	9			1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_214270	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK346310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01049009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M19733	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M27697	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000024132 ⟹ ENSSSCP00000024781

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	6	129,343,592 - 129,375,724 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000057198 ⟹ ENSSSCP00000052033

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	6	129,247,176 - 129,254,859 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000086239 ⟹ ENSSSCP00000060831

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	6	129,343,589 - 129,374,881 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000089288 ⟹ ENSSSCP00000063912

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	6	129,353,341 - 129,375,724 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000090873 ⟹ ENSSSCP00000062344

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	6	129,247,354 - 129,375,720 (+)	Ensembl

RefSeq Acc Id:

NM_214270 ⟹ NP_999435

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	6	129,343,632 - 129,374,833 (+)	NCBI

Sequence:

show sequence

GCAAAGGGAAATGGCTCATTACCGTAATGACTACAAAAAGAATGATGAGGTAGAGTTTGTCCGA
ACTGGCTATGGGAAGGATATGATAAAAGTTCTCCATATTCAGCGAGATGGAAAATATCACAGCA
TTAAAGAGGTGGCAACTTCAGTGCAACTGACTTTGAGCTCCAAAAAAGATTACCTGCATGGAGA
CAATTCAGATGTCATCCCTACAGACACCATCAAGAACACAGTTAATGTCCTGGCGAAGTTCAAA
GGCATCAAAAGCATAGAAACTTTTGCTGTGACTATCTGTGAGCATTTCCTTTCTTCCTTCAAGC
ATGTCATCAGAGCTCAAGTCTATGTGGAAGAAGTTCCTTGGAAGCGTTTTGAAAAGAATGGAGT
TAAGCATGTCCATGCATTTATTTATACTCCTACTGGAACGCACTTCTGTGAGGTTGAACAGATA
AGGAATGGACCTCCAGTCATTCATTCTGGAATCAAAGACCTAAAAGTCTTGAAAACAACCCAGT
CTGGCTTTGAAGGATTCATCAAGGACCAGTTCACCACCCTCCCTGAGGTGAAGGACCGGTGCTT
TGCCACCCAAGTGTACTGCAAATGGCGCTACCACCAGGGCAGAGATGTGGACTTTGAGGCCACC
TGGGACACTGTTAGGAGCATTGTCCTGCAGAAATTTGCTGGGCCCTATGACAAAGGCGAGTACT
CGCCCTCTGTCCAGAAGACACTCTATGACATCCAGGTGCTCACCCTGGGCCAGGTTCCTGAGAT
AGAAGATATGGAAATCAGCCTGCCAAATATTCACTACTTAAACATAGACATGTCCAAAATGGGA
CTGATCAACAAGGAAGAGGTCTTGCTACCTTTAGACAATCCATATGGCAGGATTACTGGTACAG
TCAAGAGGAAGCTGACTTCAAGGCTGTGATGTTATGGCCC

hide sequence

Protein Sequences


Protein RefSeqs	NP_999435	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA31140	(Get FASTA)	NCBI Sequence Viewer
	AAA31141	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000024781
	ENSSSCP00000024781.2
	ENSSSCP00000063912.1
	ENSSSCP00005028656.1
	ENSSSCP00015035726.1
	ENSSSCP00025008679.1
	ENSSSCP00030027373.1
	ENSSSCP00035014752.1
	ENSSSCP00040008566.1
	ENSSSCP00045044403.1
	ENSSSCP00050029895.1
	ENSSSCP00055029335.1
	ENSSSCP00060008810.1
	ENSSSCP00065035195.1
	ENSSSCP00070034126.1
	ENSSSCP00070034130.1
	ENSSSCP00070034139.1
	ENSSSCP00070034143.1
	ENSSSCP00070034147.1
	ENSSSCP00070034155.1
GenBank Protein	P16164	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_999435 ⟸ NM_214270
- Peptide Label:	precursor
- UniProtKB:	P16164 (UniProtKB/Swiss-Prot), A0A4X1UZG8 (UniProtKB/TrEMBL), I3LL15 (UniProtKB/TrEMBL), A0A8D1R1Z2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAHYRNDYKKNDEVEFVRTGYGKDMIKVLHIQRDGKYHSIKEVATSVQLTLSSKKDYLHGDNSD VIPTDTIKNTVNVLAKFKGIKSIETFAVTICEHFLSSFKHVIRAQVYVEEVPWKRFEKNGVKHV HAFIYTPTGTHFCEVEQIRNGPPVIHSGIKDLKVLKTTQSGFEGFIKDQFTTLPEVKDRCFATQ VYCKWRYHQGRDVDFEATWDTVRSIVLQKFAGPYDKGEYSPSVQKTLYDIQVLTLGQVPEIEDM EISLPNIHYLNIDMSKMGLINKEEVLLPLDNPYGRITGTVKRKLTSRL hide sequence

RefSeq Acc Id:

ENSSSCP00000063912 ⟸ ENSSSCT00000089288

RefSeq Acc Id:

ENSSSCP00000062344 ⟸ ENSSSCT00000090873

RefSeq Acc Id:

ENSSSCP00000060831 ⟸ ENSSSCT00000086239

RefSeq Acc Id:

ENSSSCP00000024781 ⟸ ENSSSCT00000024132

RefSeq Acc Id:

ENSSSCP00000052033 ⟸ ENSSSCT00000057198

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000022206	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00005029188	UniProtKB/TrEMBL
	ENSSSCG00015065247	UniProtKB/Swiss-Prot
	ENSSSCG00025015676	UniProtKB/TrEMBL
	ENSSSCG00030042839	UniProtKB/Swiss-Prot
	ENSSSCG00035027951	UniProtKB/Swiss-Prot
	ENSSSCG00040015135	UniProtKB/Swiss-Prot
	ENSSSCG00045036383	UniProtKB/Swiss-Prot
	ENSSSCG00050051079	UniProtKB/Swiss-Prot
	ENSSSCG00055018859	UniProtKB/TrEMBL
	ENSSSCG00060016087	UniProtKB/Swiss-Prot
	ENSSSCG00065059057	UniProtKB/Swiss-Prot
	ENSSSCG00070020442	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000024132	ENTREZGENE
	ENSSSCT00000024132.3	UniProtKB/TrEMBL
	ENSSSCT00000089288.1	UniProtKB/TrEMBL
	ENSSSCT00005046622.1	UniProtKB/TrEMBL
	ENSSSCT00015087661.1	UniProtKB/Swiss-Prot
	ENSSSCT00025021106.1	UniProtKB/TrEMBL
	ENSSSCT00030059752.1	UniProtKB/Swiss-Prot
	ENSSSCT00035036996.1	UniProtKB/Swiss-Prot
	ENSSSCT00040020425.1	UniProtKB/Swiss-Prot
	ENSSSCT00045063004.1	UniProtKB/Swiss-Prot
	ENSSSCT00050069554.1	UniProtKB/Swiss-Prot
	ENSSSCT00055036900.1	UniProtKB/TrEMBL
	ENSSSCT00060021426.1	UniProtKB/Swiss-Prot
	ENSSSCT00065080836.1	UniProtKB/Swiss-Prot
	ENSSSCT00070040667.1	UniProtKB/TrEMBL
	ENSSSCT00070040672.1	UniProtKB/TrEMBL
	ENSSSCT00070040682.1	UniProtKB/TrEMBL
	ENSSSCT00070040689.1	UniProtKB/TrEMBL
	ENSSSCT00070040693.1	UniProtKB/TrEMBL
	ENSSSCT00070040701.1	UniProtKB/TrEMBL
Gene3D-CATH	Urate Oxidase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Uricase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Uricase_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	ssc:397510	UniProtKB/Swiss-Prot
NCBI Gene	UOX	ENTREZGENE
PANTHER	PTHR42874	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	URICASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Uricase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF	Urate_oxidase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	URICASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	URICASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Tetrahydrobiopterin biosynthesis enzymes-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A4X1UZ22_PIG	UniProtKB/TrEMBL
	A0A4X1UZG8	ENTREZGENE
	A0A4X1V0F7_PIG	UniProtKB/TrEMBL
	A0A4X1V0H1_PIG	UniProtKB/TrEMBL
	A0A5G2QGL7_PIG	UniProtKB/TrEMBL
	A0A8D0JS72_PIG	UniProtKB/TrEMBL
	A0A8D1R1Z2	ENTREZGENE, UniProtKB/TrEMBL
	I3LL15	ENTREZGENE, UniProtKB/TrEMBL
	P16164	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	A0A4X1UZG8	UniProtKB/TrEMBL
VGNC ID	VGNC:109166	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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