PANK2 (pantothenate kinase 2) - Rat Genome Database

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Gene: PANK2 (pantothenate kinase 2) Sus scrofa
Analyze
Symbol: PANK2
Name: pantothenate kinase 2
RGD ID: 13856672
Description: ENCODES a protein that exhibits ATP binding (inferred); pantothenate kinase activity (inferred); INVOLVED IN aerobic respiration (ortholog); coenzyme A biosynthetic process (ortholog); mitochondrion organization (ortholog); ASSOCIATED WITH cone-rod dystrophy (ortholog); dystonia (ortholog); genetic disease (ortholog); FOUND IN mitochondrial intermembrane space (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pantothenate kinase 2, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1731,798,785 - 31,828,496 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11731,797,604 - 31,844,301 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21736,139,594 - 36,169,170 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IBA,IEA)
mitochondrial intermembrane space  (IEA,ISO)
mitochondrion  (IEA,ISO)
nucleus  (IBA,IEA)

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PANK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1731,798,785 - 31,828,496 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11731,797,604 - 31,844,301 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21736,139,594 - 36,169,170 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PANK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38203,888,781 - 3,929,887 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl203,888,839 - 3,929,887 (+)EnsemblGRCh38hg38GRCh38
GRCh37203,869,428 - 3,910,534 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36203,817,486 - 3,852,502 (+)NCBINCBI36Build 36hg18NCBI36
Build 34203,818,456 - 3,852,501NCBI
Celera203,931,353 - 3,966,375 (+)NCBICelera
Cytogenetic Map20p13NCBI
HuRef203,818,171 - 3,853,155 (+)NCBIHuRef
CHM1_1203,869,486 - 3,904,501 (+)NCBICHM1_1
T2T-CHM13v2.0203,919,717 - 3,960,811 (+)NCBIT2T-CHM13v2.0
Pank2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392131,103,928 - 131,141,108 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2131,104,415 - 131,141,108 (+)EnsemblGRCm39 Ensembl
GRCm382131,262,008 - 131,299,188 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2131,262,495 - 131,299,188 (+)EnsemblGRCm38mm10GRCm38
MGSCv372131,088,236 - 131,124,924 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,953,941 - 130,988,132 (+)NCBIMGSCv36mm8
Celera2132,488,862 - 132,525,361 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.31NCBI
Pank2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83138,936,448 - 138,974,196 (+)NCBIGRCr8
mRatBN7.23118,483,382 - 118,519,551 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3118,483,444 - 118,518,320 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3122,377,611 - 122,412,651 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,977,021 - 131,011,891 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03128,633,718 - 128,668,758 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03123,807,911 - 123,841,797 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,807,952 - 123,841,797 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03130,303,253 - 130,340,189 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,970,527 - 119,004,728 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,874,080 - 118,910,207 (+)NCBI
Celera3117,291,291 - 117,326,233 (+)NCBICelera
Cytogenetic Map3q36NCBI
Pank2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541514,723,087 - 14,751,423 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541514,722,951 - 14,752,493 (+)NCBIChiLan1.0ChiLan1.0
PANK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2214,851,394 - 4,886,600 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1204,848,256 - 4,883,409 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0203,924,054 - 3,959,393 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1203,723,211 - 3,757,748 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl203,723,211 - 3,757,748 (+)Ensemblpanpan1.1panPan2
PANK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12417,461,406 - 17,475,248 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2417,463,447 - 17,490,360 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2417,289,857 - 17,319,601 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02417,878,250 - 17,908,675 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2417,881,208 - 17,908,663 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12417,473,257 - 17,503,635 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02417,585,849 - 17,614,588 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02417,912,622 - 17,942,441 (-)NCBIUU_Cfam_GSD_1.0
Pank2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640166,353,587 - 166,381,146 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648514,785,467 - 14,811,117 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648514,785,050 - 14,804,258 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PANK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1234,577,859 - 34,612,258 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl234,578,207 - 34,611,987 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660719,839,672 - 9,873,822 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pank2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247414,966,260 - 5,007,207 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247414,966,136 - 5,025,465 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PANK2
1311 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3 2 19 1
Low 10 4 3 2 4 2 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000007814   ⟹   ENSSSCP00000007604
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1731,798,776 - 31,828,496 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000040048   ⟹   ENSSSCP00000050618
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1731,798,785 - 31,828,496 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000088825   ⟹   ENSSSCP00000063441
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1731,802,490 - 31,828,481 (-)Ensembl
RefSeq Acc Id: XM_005672769   ⟹   XP_005672826
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11731,799,219 - 31,828,243 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005672770   ⟹   XP_005672827
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11731,799,219 - 31,828,481 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013985149   ⟹   XP_013840603
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11731,799,219 - 31,820,696 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021078058   ⟹   XP_020933717
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11731,799,219 - 31,844,252 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021078059   ⟹   XP_020933718
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11731,797,604 - 31,822,196 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021078060   ⟹   XP_020933719
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11731,797,604 - 31,844,301 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021078061   ⟹   XP_020933720
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11731,797,604 - 31,828,155 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020933719   ⟸   XM_021078060
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_020933720   ⟸   XM_021078061
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_020933718   ⟸   XM_021078059
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_020933717   ⟸   XM_021078058
- Peptide Label: isoform X1
- UniProtKB: A0A4X1V6T8 (UniProtKB/TrEMBL),   A0A8D1KDY2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005672827   ⟸   XM_005672770
- Peptide Label: isoform X3
- UniProtKB: A0A5G2QHT0 (UniProtKB/TrEMBL),   A0A8D1CSY6 (UniProtKB/TrEMBL),   A0A8D1GJ90 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005672826   ⟸   XM_005672769
- Peptide Label: isoform X3
- UniProtKB: A0A5G2QHT0 (UniProtKB/TrEMBL),   A0A8D1CSY6 (UniProtKB/TrEMBL),   A0A8D1GJ90 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013840603   ⟸   XM_013985149
- Peptide Label: isoform X2
- UniProtKB: A0A8D1CSY6 (UniProtKB/TrEMBL),   A0A8D1GJ90 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000050618   ⟸   ENSSSCT00000040048
RefSeq Acc Id: ENSSSCP00000063441   ⟸   ENSSSCT00000088825
RefSeq Acc Id: ENSSSCP00000007604   ⟸   ENSSSCT00000007814


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000007142 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005045302 UniProtKB/TrEMBL
  ENSSSCG00015016747 UniProtKB/TrEMBL
  ENSSSCG00025056311 UniProtKB/TrEMBL
  ENSSSCG00030044241 UniProtKB/TrEMBL
  ENSSSCG00035033939 UniProtKB/TrEMBL
  ENSSSCG00040049403 UniProtKB/TrEMBL
  ENSSSCG00045003887 UniProtKB/TrEMBL
  ENSSSCG00050076544 UniProtKB/TrEMBL
  ENSSSCG00055020323 UniProtKB/TrEMBL
  ENSSSCG00060020327 UniProtKB/TrEMBL
  ENSSSCG00065055536 UniProtKB/TrEMBL
  ENSSSCG00070022190 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000040048.3 UniProtKB/TrEMBL
  ENSSSCT00000088825 ENTREZGENE
  ENSSSCT00000088825.2 UniProtKB/TrEMBL
  ENSSSCT00005073161.1 UniProtKB/TrEMBL
  ENSSSCT00015022182.1 UniProtKB/TrEMBL
  ENSSSCT00015022273.1 UniProtKB/TrEMBL
  ENSSSCT00015022366.1 UniProtKB/TrEMBL
  ENSSSCT00025077046.1 UniProtKB/TrEMBL
  ENSSSCT00025077212.1 UniProtKB/TrEMBL
  ENSSSCT00025077312.1 UniProtKB/TrEMBL
  ENSSSCT00030061698.1 UniProtKB/TrEMBL
  ENSSSCT00030061720.1 UniProtKB/TrEMBL
  ENSSSCT00030061749.1 UniProtKB/TrEMBL
  ENSSSCT00035044991.1 UniProtKB/TrEMBL
  ENSSSCT00035044997.1 UniProtKB/TrEMBL
  ENSSSCT00035045008.1 UniProtKB/TrEMBL
  ENSSSCT00040066586.1 UniProtKB/TrEMBL
  ENSSSCT00040066750.1 UniProtKB/TrEMBL
  ENSSSCT00040066902.1 UniProtKB/TrEMBL
  ENSSSCT00045006440.1 UniProtKB/TrEMBL
  ENSSSCT00045006459.1 UniProtKB/TrEMBL
  ENSSSCT00045006464.1 UniProtKB/TrEMBL
  ENSSSCT00045006478.1 UniProtKB/TrEMBL
  ENSSSCT00050105174.1 UniProtKB/TrEMBL
  ENSSSCT00050105175.1 UniProtKB/TrEMBL
  ENSSSCT00050105176.1 UniProtKB/TrEMBL
  ENSSSCT00055039844.1 UniProtKB/TrEMBL
  ENSSSCT00055039936.1 UniProtKB/TrEMBL
  ENSSSCT00055040108.1 UniProtKB/TrEMBL
  ENSSSCT00060027511.1 UniProtKB/TrEMBL
  ENSSSCT00060027513.1 UniProtKB/TrEMBL
  ENSSSCT00060027517.1 UniProtKB/TrEMBL
  ENSSSCT00065076027.1 UniProtKB/TrEMBL
  ENSSSCT00065076036.1 UniProtKB/TrEMBL
  ENSSSCT00070044110.1 UniProtKB/TrEMBL
  ENSSSCT00070044117.1 UniProtKB/TrEMBL
  ENSSSCT00070044123.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.420.40 UniProtKB/TrEMBL
  3.30.420.510 UniProtKB/TrEMBL
InterPro ATPase_NBD UniProtKB/TrEMBL
  Type_II_PanK UniProtKB/TrEMBL
KEGG Report ssc:100520054 UniProtKB/TrEMBL
NCBI Gene PANK2 ENTREZGENE
PANTHER PANTOTHENATE KINASE 2, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR12280 UniProtKB/TrEMBL
Pfam Fumble UniProtKB/TrEMBL
Superfamily-SCOP SSF53067 UniProtKB/TrEMBL
UniProt A0A287B3C3_PIG UniProtKB/TrEMBL
  A0A4X1V384_PIG UniProtKB/TrEMBL
  A0A4X1V6T8 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V6U7_PIG UniProtKB/TrEMBL
  A0A5G2QHT0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1CSY6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1GJ90 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1KDY2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:95695 ENTREZGENE